Surfing the nano-wave:Emerging trends in cancer diagnostics and therapy
作者机构：Laboratory of Medical GeneticsHarbin Medical UniversityHarbin 150081China Key Laboratory of Preservation of Human Genetics Resources and Disease Control in China(Harbin Medical University)Ministry of EducationHarbin 150081China Beijing Key Laboratory for Optical Materials and Photonic DevicesDepartment of ChemistryCapital Normal UniversityBeijing 100048China College of Materials and Chemical EngineeringKey Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Washington University School of Medicine in St.LouisSt.LouisMO 63110USA Ningbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Aix-Marseille CollegeWuhan University of TechnologyWuhan 430070China
出 版 物：《Nano Research》 (纳米研究（英文版）)
年 卷 期：2025年第18卷第1期
页 面：520-544页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by the Open Project of the Key Laboratory of Genetic Resources Protection and Disease Prevention and Control of the Ministry of Education of China(No.LPHGRDC2020-002) the Major Marshal List Project of Harbin Medical University(No.HMUMIF-21007) the National Natural Science Foundation of China(No.22305051) the member of Youth Innovation Promotion Association Foundation of CAS,China(No.2023310)
主 题：nanoparticles drug delivery gastric cancer glioma glioblastoma
摘 要：Facing the growing global challenge posed by cancer,the quest for more accurate and potent cancer diagnostic and therapeutic strategies continues to require a multidisciplinary integration *** review firstly summarizes various types of nanoparticles in cancer ***,it offers a comprehensive overview of signalenhancing techniques for visualizing in situ tumors,along with multimodal diagnostic methods for detecting *** for tumor therapy,cutting-edge drug delivery methods that can cross biological barriers and the pinpoint targeting of tumor lesions for precise medical intervention are *** the domain of therapeutic diagnostics,we elucidate the theoretical underpinnings and structural paradigms that underlie a spectrum of advanced diagnostic and therapeutic ***,we present a compendium of publications delineating the clinical applications of each nano-based theragnostic integration ***,this comprehensive review discusses the safety concerns pertaining to the clinical application of nanoparticles and proposes some strategic recommendations to enhance the precision and safety of theragnostic-guided,nanotechnology-based clinical practices.A deeper understanding of nanomaterials,together with intimate interdisciplinary collaborations,nano-wave will most probably guide human beings to win the battle against cancers.
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