检索结果-南通市图书馆

Metabolic shift in liver: Correlation between perfusion temperature and hypoxia inducible factor-1α

World Journal of Gastroenterology 2015年第4期21卷 1108-1116页

作者： Andrea ferrigno Laura Giuseppina Di Pasqua Alberto bianchi Plinio Richelmi Mariapia VairettiAndrea ferrigno Unit of Cellular and Molecular Pharmacology and Toxicology Department of Interna Medicine and TherapeuticsUniversity of PaviaPavia 27100 Italy

AIM: To study at what temperature the oxygen carried by the perfusate meets liver requirements in a model of organ perfusion. METHODS: in this study, we correlated hypoxia induciblefactor(Hi f)-1α expression to the perfusion temperature and the hepatic oxygen uptake in a model of isolated perfused rat liver. Livers from Wistar rats were perfused for 6 h with an oxygenated medium at 10, 20, 30 and 37 ℃. Oxygen uptake was measured by an oxygen probe; lactate dehydrogenase activity, lactate release and glycogen were measured spectrophotometrically; bile flow was gravitationally determined; p H of the perfusate was also evaluated; Hi f-1α m RNA and protein expression were analyzed by real time-polymerase chain reaction and ELi SA, respectively. RESULTS: Livers perfused at 10 and 20 ℃ showed no difference in lactate dehydrogenase release after 6 h of perfusion(0.96 ± 0.23 vs 0.93 ± 0.09 m U/min per g) and had lower hepatic damage as compared to 30 and 37 ℃(5.63 ± 0.76 vs 527.69 ± 45.27 m U/min per g, respectively, P s fter 6 h, tissue ATP was significantly higher in livers perfused at 10 and 20 ℃than in livers perfused at 30 and 37 ℃(0.89 ± 0.06 and 1.16 ± 0.05 vs 0.57 ± 0.09 and 0.33 ± 0.08 nmol/mg, respectively, P s f hypoxia was observed at 10 and 20 ℃, as highlighted by low lactate release respect to livers perfused at 30 and 37 ℃(121.4 ± 12.6 and 146.3 ± 7.3 vs 281.8 ± 45.3 and 1094.5 ± 71.7 nmol/m L, respectively, P s f-1α m RNA(0.40 ± 0.08 and 0.20 ± 0.03 vs 0.60 ± 0.20 and 1.47 ± 0.30, respectively, P s fused at 10 and 20 ℃ show no sign of liver injury or anaerobiosis, in contrast to livers perfused at 30 and 37 ℃.

关键词： Anaerobiosis Hypoxia inducible factor-1 α ischemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mepolizumab induced palmoplantar psoriasis:A case report

引用

World Journal of Clinical Cases 2023年第26期11卷 6154-6158页

作者： fabio Artosi Laura Diluvio Martina Vultaggio Elena Campione Luca bianchi Department of Systems Medicine University of Rome“Tor Vergata”Rome 00133Italy Department of Dermatology Dermatology UnitPoliclinico Tor VergataRome 00133Italy Department of Dermatology University Roma Tor VergataRome 00133Italy

BACKGROUND Atopic dermatitis and asthma are two diseases whose pathogenesis is largely attributable to the activation,at least in the initial stages,of T helper(Th)-2 Lymphocytes,the related cytokine axis,and B lymphocytes with antibody *** is conversely a pathology resulting from a recruitment of Th-17 and Th-1 lymphocytes,after an initial role of innate *** is a humanized monoclonal antibody directed against interleukin(IL)-5,a central cytokine in the Th-2 axis,therefore involved in the pathogenesis of *** authors have described the appearance of psoriatic lesions in patients with asthma or atopic dermatitis following the therapy with dupilumab,a monoclonal antibody that blocks the interleukin(IL)-4,another Th-2 *** SUMMARY We present the case of a 59-year-old patient who developed psoriasiform lesions on the palms after mepolizumab therapy for asthma,for the activation of the parallel cytokine cascade after the blockade of *** successfully treated the patient with a topical calcipotriol and betamethasone *** We should investigate with further attention the possible impact on the human immunological ecosystem put in place by the inhibition of the activity of individual inflammatory mediators,so as to be able to recognize the initial adverse effects early.

关键词： Psoriasis Interleukin-5 Mepolizumab Asthma Immunology Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Evidence for e^+e^-→γχ_(c1,2) at center-of-mass energies from 4.009 to 4.360 GeV

引用

Chinese Physics C 2015年第4期39卷 1-9页

作者：麦迪娜 M.N.Achasov 艾小聪 O.Albayrak M.Albrecht D.J.Ambrose A.Amoroso 安芬芬安琪白景芝 R.Baldini ferroli 班勇 D.W.Bennett J.V.Bennett M.Bertani D.Bettoni 边渐鸣 f.bianchi E.Boger O.Bondarenko I.Boyko R.A.Briere 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈海云陈江川陈玛丽陈申见谌炫陈旭荣陈元柏程和平褚新坤 G.Cibinetto D.Cronin-Hennessy 代洪亮代建平 A.Dbeyssi D.Dedovich 邓子艳 A.Denig I.Denysenko M.Destefani f.De Mori 丁勇董超董静董燎原董明义杜书先段鹏飞范荆州方建房双世方馨方易 L.fava f.feldbauer G.felici 封常青 E.fioravanti M.fritsch 傅成栋高清高原宁高榛 I.Garzia K.Goetzen 龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭墩郭玥 Y.P.Guo Z.Haddadi A.Hafner 韩爽韩艳良 f.A.Harris 何康林何振亚 T.Held 衡月昆侯治龙胡琛胡海明胡继峰胡涛胡誉黄光明黄光顺黄海鹏黄金书黄性涛黄勇 T.Hussain 纪全姬清平季晓斌季筱璐姜丽丽姜鲁文江晓山焦健斌焦铮金大鹏金山 T.Johansson A.Julin N.Kalantar-Nayestanaki 康晓琳康晓珅 M.Kavatsyuk B.C.Ke R.Kliemt B.Kloss O.B.Kolcu B.Kopf M.Kornicer W.Kuehn A.Kupsc 赖蔚 J.S.Lange M.Lara P.Larin 李春花李澄李德民李飞李刚李海波李家才李瑾李康李科李培荣李腾李卫东李卫国李晓玲李小梅李小男李学潜李志兵梁昊梁勇飞梁羽铁廖广睿 Lin 刘北江 C.L.Liu 刘春秀刘福虎刘芳刘峰刘宏邦刘汇慧刘欢欢刘怀民刘杰刘觉平刘晶译刘凯刘魁勇刘兰雕刘佩莲刘倩刘树彬刘翔刘晓霞刘玉斌刘振安刘志强 Zhiqiang Liu H.Loehner 娄辛丑吕海江吕军光鲁睿其卢宇卢云鹏罗成林罗民兴 T.Luo 罗小兰吕蒙吕晓睿马凤才马海龙马连良马秋梅马斯马天马旭宁马骁妍 f.E.Maas M.Maggiora Q.A.Malik 冒亚军毛泽普 S.Marcello J.G.Messchendorp 闵建闵天觉 R.E.Mitchell 莫晓虎莫玉俊 C.Morales Morale K.Moriya N.Yu.Muchnoi H.Muramatsu Y.Nefedov f.Nerling I.B.Nikolaev 宁哲 S.Nisar 牛顺利牛讯伊马鹏欧阳群 S.Pacetti P.Patteri M.Pelizaeus 彭海平 K.Peters 平加伦平荣刚 R.Poling 濮亚男祁鸣钱森乔从丰秦丽清覃拈秦小帅秦瑶秦中华邱进发 K.H.Rashid C.f.Redmer 任海龙 M.Ripka 荣刚阮向东 V.Santoro A.Sarantsev M.Savrié K.Schoenning S.Schumann 单葳邵明沈成平沈培迅沈肖雁盛华义 M.R.Shepherd 宋维民宋欣颖 S.Sosio S.Spataro B.Spruck 孙功星孙俊峰孙胜森孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thorndike M.Tiemens D.Toth M.Ullrich I.Uman G.S.Varner 王斌王滨龙王东王大勇王科王亮亮王灵淑王萌王平王佩良王庆娟王思广王炜王雄飞 Yadi 王贻芳王亚乾王铮王志刚王志宏王至勇 T.Weber 魏代会韦江波 P.Weidenkaff 文硕频 U.Wiedner M.Wolke 伍灵慧吴智夏力钢夏宇肖栋肖振军谢宇广许国发徐雷徐庆君徐庆年徐新平严亮鄢文标闫文成颜永红杨洪勋杨柳杨迎杨永栩叶桦叶梅叶铭汉殷俊昊俞伯祥喻纯旭于海旺俞洁晟苑长征袁文龙袁野 A.Yuncu A.A.Zafar A.Zallo 曾云张丙新张炳云张驰张长春张达华张宏浩章红宇张佳佳张杰 Institute of High Energy Physics Chinese Academy of Sciences G.I. Budker Institute of Nuclear Physics SB RAS (BINP) the Novosibirsk State University Carnegie Mellon University Bochum Ruhr-University University of Rochester University of Turin INfN University of Science and Technology of China INfN Laboratori Nazionali di frascati Peking University Indiana University INfN Sezione di ferrara University of Minnesota Joint Institute for Nuclear Research the Moscow Institute of Physics and Technology KVI-CART University of Groningen Wuhan University Istanbul Aydin University Ankara University Dogus University the functional Electronics Laboratory Tomsk State University Beihang University Nanjing University Lanzhou University Huangshan College Shanghai Jiao Tong University Helmholtz Institute Mainz Johannes Gutenberg University of Mainz Liaoning University Nankai University Zhengzhou University Tsinghua University University of Eastern Piedmont GSI Helmholtzcentre for Heavy Ion Research Gmb H D-64291 Darmstadt Germany Guangxi University Nanjing Normal University University of Hawaii Central China Normal University Henan Normal University Shandong University University of the Punjab Uppsala University Currently at Istanbul Arel University Justus Liebig University Giessen Ⅱ. Physikalisches Institut Seoul National University Hangzhou Normal University University of Chinese Academy of Sciences Sun Yat-Sen University Sichuan University Guangxi Normal University Shanxi University Henan University of Science and Technology University of Texas at Dallas Hunan University Zhejiang University COMSATS Institute of Information Technology INfN and University of Perugia GSI Helmholtzcentre for Heavy Ion Research Gmb H the PNPI University of ferrara Indiana University Bloomington Uludag University Soochow University China Center of Advanced Science and Technology Bogazici University University of South China

Using data samples collected at center-of-mass energies of √s=4.009, 4.230, 4.260, and 4.360 GeV with the BES0 detector operating at the BEPC/ collider, we perform a search for the process e＋e-→γχc,j （J =0, 1, 2） and find evidence for e＋e-→γχc1 and e＋e-→γχc2 with statistical significances of 3.0σ and 3.4σ, respectively. The Born cross sections σB（e＋e-→γχc,j）, as well as their upper limits at the 90% con dence level （C.L.） are determined at each center-of-mass energy.

关键词： heavy quarkonia decays of hadronic electron-positron collisions hadron production by

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Liver involvement in the course of thymoma-associated multiorgan autoimmunity:The first histological description

引用

Hepatobiliary & Pancreatic Diseases International 2022年第1期21卷 86-89页

作者： fabrizio Citarella Umberto Vespasiani-Gentilucci Anna Crescenzi Antonella bianchi Vladimir Virzì Giuseppe Tonini Department of Medical Oncology Policlinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy Area of Internal Medicine Unit of HepatologyPoliclinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy Unit of Pathology Policlinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy

To the Editor:Thymoma-associated multiorgan autoimmunity(TAMA)is a rare paraneoplastic syndrome described in patients with thymoma and characterized by multiorgan failure and graft-versus-host dis-ease(GVHD)like pathology affecting the skin,the gastrointestinal tract,and the *** date,only 21 cases are reported in liter-ature[1],with some patients presenting gastrointestinal and hep-atic manifestations,mainly colitis,diarrhea,and abnormal liver en-zymes,but the hepatic involvement has not been histologically characterized yet.

关键词： involvement gastrointestinal diarrhea

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Determination of the number of J/ψ events with inclusive J/ψ decays

引用

Chinese Physics C 2017年第6期41卷 1-10页

作者：麦迪娜 M.N.Achasov 艾小聪 O.Albayrak M.Albrecht D.J.Ambrose A.Amoroso 安芬芬安琪白景芝 R.Baldini ferroli 班勇 D.W.Bennett J.V.Bennett M.Bertani D.Bettoni 边渐鸣 f.bianchi E.Boger I.Boyko R.A.Briere 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 S.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈海云陈江川陈玛丽陈申见谌炫陈旭荣陈元柏程和平褚新坤 G.Cibinetto 代洪亮代建平 A.Dbeyssi D.Dedovich 邓子艳 A.Denig I.Denysenko M.Destefanis f.De Mori 丁勇董超董静董燎原董明义豆正磊杜书先段鹏飞范荆州方建房双世方馨方易 R.farinelli L.fava O.fedorov f.feldbauer G.felici 封常青 E.fioravanti M.fritsch 傅成栋高清高鑫磊高旭阳高原宁高榛 I.Garzia K.Goetzen 龚丽龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭玥郭玉萍 Z.Haddadi A.Hafner 韩爽郝喜庆 f.A.Harris 何康林 T.Held 衡月昆侯治龙胡琛胡海明胡继峰胡涛胡誉黄光顺黄金书黄性涛黄勇 T.Hussain 纪全姬清平季晓斌季筱璐姜鲁文江晓山蒋兴雨焦健斌焦铮金大鹏金山 T.Johansson A.Julin N.Kalantar-Nayestanaki 康晓琳康晓珅 M.Kavatsyuk 柯百谦 P.Kiese R.Kliemt B.Kloss 0.B.Kolcu B.Kopf M.Kornicer A.Kupsc W.Kuhn J.S.Lange M.Lara P.Larin C.Leng 李翠李澄李德民李飞李峰云李刚李海波李家才李瑾李科李康李蕾李培荣李启云李腾李卫东李卫国李晓玲李小男李学潜李志兵梁昊梁勇飞梁羽铁廖广睿林德旭刘北江刘春秀刘栋刘福虎刘芳刘峰刘宏邦刘欢欢刘慧慧刘怀民刘杰刘建北刘觉平刘晶译刘凯刘魁勇刘兰雕刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘智青 H.Loehner 娄辛丑吕海江吕军光卢宇卢云鹏罗成林罗民兴 T.Luo 罗小兰吕晓睿马凤才马海龙马连良马秋梅马天马旭宁马骁妍马玉明 f.E.Maas M.Maggiora 冒亚军毛泽普 S.Marcello J.G.Messchendorp 闵建闵天觉 R.E.Mitchell 莫晓虎莫玉俊 C.Morales Morales N.Yu.Muchnoi H.Muramatsu Y.Nefedov f.Nerling I.B.Nikolaev 宁哲 S.Nisar 牛顺利牛讯伊马鹏欧阳群 S.Pacetti 潘越 P.Patteri M.Pelizaeus 彭海平 K.Peters J.Pettersson 平加伦平荣刚 R.Poling V.Prasad 漆红荣祁鸣钱森乔从丰秦丽清覃拈秦小帅秦中华邱进发 K.H.Rashid C.f.Redmer M.Ripka 荣刚 Ch.Rosner 阮向东 V.Santoro A.Sarantsev M.Savrie K.Schoenning S.Schumann 单葳邵明沈成平沈培迅沈肖雁盛华义宋维民宋欣颖 S.Sosio S.Spataro 孙功星孙俊峰孙胜森孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.Tapan E.H.Thorndike M.Tiemens M.Ullrich I.Uman G.S.Varner 王斌王滨龙王东王大勇王科王亮亮王灵淑王萌王平王佩良王炜王维平王雄飞王雅迪王贻芳王亚乾王铮王志刚王志宏王至勇 T.Weber 魏代会 P.Weidenkaff 文硕频 U.Wiedner M.Wolke 伍灵慧吴智夏磊夏力钢夏宇肖栋肖浩肖振军谢宇广修青磊许国发徐雷徐庆君徐庆年徐新平严亮鄢文标闫文成颜永红杨海军杨洪勋杨柳杨永栩叶梅叶铭汉殷俊昊俞伯祥喻纯旭俞洁晟苑长征袁文龙袁野 A.Yuncu A.A.Zafar A.Zallo 曾云曾哲张丙新张炳云张驰张长春张达华张宏浩章红宇张佳佳张杰磊张敬庆张家文张建勇张景芝张坤张磊张学尧张瑶张银鸿张宇宁张亚腾 Institute of High Energy Physics G.I. Budker Institute of Nuclear Physics SB RAS (BINP) the Novosibirsk State University Carnegie Mellon University Bochum Ruhr-University University of Rochester University of Turin INfN University of Science and Technology of China State Key Laboratory of Particle Detection and Electronics INfN Laboratori Nazionali di frascati Peking University Indiana University INfN Sezione di ferrara University of Minnesota Joint Institute for Nuclear Research the Moscow Institute of Physics and Technology Wuhan University Ankara University Istanbul Bilgi University the functional Electronics Laboratory Tomsk State University Beihang University Nanjing University Lanzhou University Huangshan College Shanghai Jiao Tong University Helmholtz Institute Mainz Johannes Gutenberg University of Mainz Liaoning University Nankai University Zhengzhou University Tsinghua University University of ferrara University of Eastern Piedmont GSI Helmholtzcentre for Heavy Ion Research GmbH Guangxi University Nanjing Normal University KVI-CART University of Groningen Henan Normal University University of Hawaii Shandong University University of the Punjab Uppsala University Istanbul Arel University Justus-Liebig-Universitaet Giessen Ⅱ. Physikalisches Institut Seoul National University Hangzhou Normal University Beijing Institute of Petrochemical Technology University of Chinese Academy of Sciences Sun Yat-Sen University Sichuan University Guangxi Normal University Shanxi University Central China Normal University Henan University of Science and Technology University of Texas at Dallas Zhejiang University COMSATS Institute of Information Technology INfN and University of Perugia Goethe University frankfurt the NRC "Kurchatov Institute PNPI Uludag University Near East University Hunan University University of South China Soochow University Institute of Nuclear and Particle Physics Shanghai Key Laboratory for Particle Physics and Cosmology China Center of Advanced Science and Technology Bogazici University Univers

A measurement of the number of J/ψ events collected with the BESⅢ detector in 2009 and 2012 is performed using inclusive decays of the J/ψ. The number of J/ψ events taken in 2009 is recalculated to be（223.7±1.4）×10^6, which is in good agreement with the previous measurement, but with significantly improved precision due to improvements in the BESⅢ software. The number of J/ψ events taken in 2012 is determined to be（1086.9±6.0）×10^6. In total, the number of J/ψ events collected with the BESⅢ detector is measured to be（1310.6±7.0）×10^6, where the uncertainty is dominated by systematic effects and the statistical uncertainty is negligible.

关键词： number of J/ψ events BESⅢ detector inclusive J/ψ events

来源：

维普期刊数据库

同方期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

＂Principal Components＂ for the Calculation of the Best Estimate Liability of future Discretionary Benefits under Solvency II

引用

Journal of Mathematics and System Science 2013年第6期3卷 271-278页

作者： Luca bianchi Appointed Actuary for the Life Entities belonging to Aviva Italia Holding Via Scarsellini 14 - 20161 - Milano Italy

The core of the presentation that I propose treats about the application of principal component analysis for the estimation of the future earnings of the Segregated funds. The Segregated funds are the pools of assets which have been using in the Italian Insurance Market since mid 80＇s for managing the ＂with profit＂ business, also known as business with ＂discretionary participation feature＂ according to IfRS4 since the income attributable to the policyholders is composed by the net realised gains less a fee and by a minimum guarantee, if any. The discretion of the Management of the Entity lays on the decision on whether and when to realise both the financial gains and the financial losses of the underlying investments. This strategy is tied by the need to manage an appropriate ALM, from the rules included in the local legislation as well as by the policy about the solvency margin （for example a minimum solvency ratio to fulfil that is conditional upon the value of income attributed that year）. The fee can not be changed, i.e., is not discretionary, the minimum granted could be fixed on annual basis-sometimes paid on cash recurrently-or could be promised only at expiration or sometimes promised at expiration or in advance only for death and disability. In case of years so adverse that the Entity is not able to avoid earnings too low, sometimes the entity delivers an additional bonus, in order to compensate their policyholders, which is based above a full discretion. Principal components are used in finance as well as in other fields such as genetic. You can see some of these applications in two of the references advised below. The purposes of the technique of principal components are （1） to increase objectivity of results and their verifiability by third parties such as auditors, （2） make speeder the time spent for the analytical calculations （i.e., runs of the actuarial models） and （3） to render the relationship between the asset composition and the their earnings ef

关键词： Liabilities in solvency II future discretionary benefits principal components.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Therapeutic strategies in Crohn’s disease in an emergency surgical setting

引用

World Journal of Gastroenterology 2022年第18期28卷 1902-1921页

作者： Maria Michela Chiarello Gilda Pepe Valeria fico Valentina bianchi Giuseppe Tropeano Gaia Altieri Giuseppe Brisinda Department of Surgery San Giovanni in Fiore HospitalAzienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Surgery Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Medical and Surgical Science UniversitàCattolica del Sacro CuoreRome 00168Italy

Crohn’s disease(CD)remains a chronic,incurable disorder that presents unique challenges to the *** factors must be considered to allow development of an appropriate treatment *** therapy often precedes or complements the surgical *** indications for operative management of CD include acute and chronic disease complications and failed medical *** surgery comes into play when patients are refractory to medical treatment if they have an obstructive *** colitis,acute obstruction,perforation,acute abscess,or massive hemorrhage represent indications for emergency *** patients are generally in critical conditions and present with intra-abdominal sepsis and a preoperative status of immunosuppression and malnutrition that exposes them to a higher risk of complications and mortality.A multidisciplinary team including surgeons,gastroenterologists,radiologists,nutritional support services,and enterostomal therapists are required for optimal patient care and decision *** of each emergency should be individualized based on patient age,disease type and duration,and patient goals of ***,the recurrent nature of disease mandates that we continue searching for innovative medical therapies and operative techniques that reduce the need to repeat surgical *** this review,we aimed to discuss the acute complications of CD and their treatment.

关键词： Crohn’s disease Intestinal obstruction free perforation Intra-abdominal sepsis Perineal sepsis Acute bleeding

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gut virome:New key players in the pathogenesis of inflammatory bowel disease

引用

World Journal of Methodology 2025年第2期15卷 27-43页

作者： Helal f Hetta Rehab Ahmed Yasmin N Ramadan Hayam fathy Mohammed Khorshid Mohamed M Mabrouk Mai Hashem Department of Medical Microbiology and Immunology Faculty of MedicineAssiut UniversityAssiut 71515Egypt Division of Microbiology Immunology and BiotechnologyFaculty of pharmacyUniversity of TabukTabuk 71491Saudi Arabia Division of Microbiology Immunology and BiotechnologyDepartment of Natural Products and Alternative MedicineFaculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Department of Internal Medicine Division HepatogastroenterologyAssiut UniversityAssiut 71515Egypt Department of Clinical Research Egyptian Developers of Gastroenterology and Endoscopy FoundationCairo 11936Egypt Department of Internal Medicine Faculty of Medicine.Tanta UniversityTanta 31527Egypt Department of Tropical Medicine Gastroenterology and HepatologyAssiut University HospitalAssiut 71515Egypt

Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the *** the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immunological response,environmental exposure,particularly the gut microbiota,and genetic suscept-ibility represents the major *** gut virome is a group of viruses found in great frequency in the gastrointestinal tract of *** gut virome varies greatly among individuals and is influenced by factors including lifestyle,diet,health and disease conditions,geography,and *** majority of research has focused on the significance of gut bacteria in the progression of IBD,although viral populations represent an important component of the *** conducted this review to highlight the viral communities in the gut and their expected roles in the etiopathogenesis of IBD regarding published research to date.

关键词： Inflammatory bowel disease Pathogenesis Gut virome Bacteriophage Eukaryotic viruses

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Total mesorectal excision for mid and low rectal cancer: laparoscopic vs robotic surgery

引用

World Journal of Gastroenterology 2016年第13期22卷 3602-3610页

作者： francesco feroci Andrea Vannucchi Paolo Pietro bianchi Stefano Cantafio Alessia Garzi Giampaolo formisano Marco Scatizzi Department of General and Oncological Surgery Santo Stefano Hospital Department of General and Minimally Invasive Surgery Misericordia Hospital

AIM: To compare the short- and long-term outcomes of laparoscopic and robotic surgery for middle and low rectal ***: This is a retrospective study on a prospectively collected database containing 111 patients who underwent minimally invasive rectal resection with total mesorectal excision (TME) with curative intent between January 2008 and December 2014 (robot, n = 53; laparoscopy, n = 58). The patients all had a diagnosis of middle and low rectal adenocarcinoma with stage I-III disease. The median follow-up period was 37.4 mo. Perioperative results, morbidity a pathological data were evaluated and compared. The 3-year overall survival and disease-free survival rates were calculated and ***: Patients were comparable in terms of preoperative and demographic parameters. The median surgery time was 192 min for laparoscopic TME (L-TME) and 342 min for robotic TME (R-TME) (P fferences found in the rates of conversion to open surgery and morbidity. The patients who underwent laparoscopic surgery stayed in the hospital two days longer than the robotic group patients (8 d for L-TME and 6 d for R-TME, P f harvested lymph nodes in the robotic group (18 for R-TME, 11 for L-TME, P for laparoscopic patients (1.5 cm for L-TME, 2.5 cm for R-TME, P free survival rates were similar between ***: Both L-TME and R-TME achieved acceptable clinical and oncologic outcomes. The robotic technique showed some advantages in rectal surgery that should be validated by further studies.

关键词： Robotic surgery Laparoscopic surgery Rectal cancer Total mesorectal excision Minimally invasive surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

SARS-CoV-2 and the pancreas: What do we know about acute pancreatitis in COVID-19 positive patients?

引用

World Journal of Gastroenterology 2022年第36期28卷 5240-5249页

作者： Giuseppe Brisinda Maria Michela Chiarello Giuseppe Tropeano Gaia Altieri Caterina Puccioni Pietro fransvea Valentina bianchi Department of Medical and Surgical Sciences Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy Department of Medicine and Surgery UniversitàCattolica del Sacro CuoreRome 00168Italy Department of Surgery Azienda Sanitaria Provinciale di CosenzaCosenza 87100Italy Emergency Surgery and Trauma Center Fondazione Policlinico Universitario A Gemelli IRCCSRome 00168Italy

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)can cause pancreatic damage,both directly to the pancreas via angiotensin-converting enzyme 2 receptors(the transmembrane proteins required for SARS-CoV-2 entry,which are highly expressed by pancreatic cells)and indirectly through locoregional vasculitis and *** that,there is no clear evidence that SARS-CoV-2 is an etiological agent of acute *** pancreatitis in coronavirus disease 2019(COVID-19)positive patients often recognizes biliary or alcoholic *** prevalence of acute pancreatitis in COVID-19 positive patients is not exactly ***,COVID-19 positive patients with acute pancreatitis have a higher mortality and an increased risk of intensive care unit admission and necrosis compared to COVID-19 negative *** respiratory distress syndrome is the most frequent cause of death in COVID-19 positive patients and concomitant acute *** this article,we reported recent evidence on the correlation between COVID-19 infection and acute pancreatitis.

关键词： Acute pancreatitis SARS-CoV-2 Severe acute pancreatitis Multiparametric scores Infected necrosis Step-up approach

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：