Liver involvement in the course of thymoma-associated multiorgan autoimmunity:The first histological description

作     者：Fabrizio Citarella Umberto Vespasiani-Gentilucci Anna Crescenzi Antonella Bianchi Vladimir Virzì Giuseppe Tonini Fabrizio Citarella;Umberto Vespasiani-Gentilucci;Anna Crescenzi;Antonella Bianchi;Vladimir Virzì;Giuseppe Tonini

作者机构：Department of Medical OncologyPoliclinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy Area of Internal MedicineUnit of HepatologyPoliclinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy Unit of PathologyPoliclinico Universitario Campus Bio-Medicovia Alvaro del PortilloRome 00128Italy 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2022年第21卷第1期

页      面：86-89页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：involvement gastrointestinal diarrhea 

摘      要：To the Editor:Thymoma-associated multiorgan autoimmunity(TAMA)is a rare paraneoplastic syndrome described in patients with thymoma and characterized by multiorgan failure and graft-versus-host dis-ease(GVHD)like pathology affecting the skin,the gastrointestinal tract,and the *** date,only 21 cases are reported in liter-ature[1],with some patients presenting gastrointestinal and hep-atic manifestations,mainly colitis,diarrhea,and abnormal liver en-zymes,but the hepatic involvement has not been histologically characterized yet.