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Transforming nanoscale VO_(2)(B) into a scalable sodium-ion electrode

nano Research 2024年第10期17卷 8809-8818页

作者： Yunkai Luo Swetha Chandrasekaran Bintao Hu Randy Chen Marcus Worsley Bruce dunn Department of Materials Science and Engineering University of CaliforniaLos AngelesCA 90095USA Lawrence Livermore national Laboratory CA 94550USA

The intermittent nature of renewable energies requires highly reliable grid-level energy storage approaches.A critical consideration in developing this technology is the areal capacity which determines battery performance and influences the cost of battery *** related importance is finding new ways of developing scalable *** recent years,threedimensional(3D)printing of conductive scaffolds has emerged as an alternative to overcome the scalability limitations of commercial tape cast *** research carried out in the current study demonstrates a successful scalability pathway for nanoscale VO_(2)(B),a desirable cathode for sodium-ion batteries which has a nano-flower morphology with a crystallite sizeng VO_(2)(B)onto a graphene aerogel scaffold,we were able to achieve mass loading of over 100 mg·cm^(-2) and still possess an areal capacity of 10 mAh·cm^(-2) at a current density of 5 mA·cm^(-2).Moreover,after 1000 cycles,these electrodes retained 75% to 80% of their initial *** at high loading levels,the electrodeposited VO_(2)(B)exhibits pseudocapacitive material signatures such as a box-like voltammetry response,linear galvanostatic response,and no phase change upon *** scalability of the VO_(2)(B)electrode is demonstrated in a series of experiments which show the areal capacity to scale upon increase in both mass loading and electrode thickness,with only small changes in specific *** study establishes that nanoscale materials can be scaled up to achieve thick electrodes without compromising their electrochemical properties.

关键词： nano VO_(2)(B) sodium-ion battery scalable electrodes three-dimensional(3D)printed scaffold additive manufacturing

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Diabetic peripheral neuropathy and neuromodulation techniques:a systematic review of progress and prospects

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neural Regeneration Research 2025年第8期20卷 2218-2230页

作者： Rahul Mittal Keelin McKenna Grant Keith evan McKenna Joana R.n.Lemos Jeenu Mittal Khemraj Hirani Diabetes Research Institute University of Miami Miller School of MedicineMiamiFLUSA Department of Otolaryngology University of Miami Miller School of MedicineMiamiFLUSA Herbert Wertheim College of Medicine Florida International UniversityMiamiFLUSA School of Medicine and Public Health University of WisconsinMadisonWIUSA

neuromodulation for diabetic peripheral neuropathy represents a significant area of interest in the management of chronic pain associated with this *** peripheral neuropathy,a common complication of diabetes,is characterized by nerve damage due to high blood sugar levels that lead to symptoms,such as pain,tingling,and numbness,primarily in the hands and *** aim of this systematic review was to evaluate the efficacy of neuromodulatory techniques as potential therapeutic interventions for patients with diabetic peripheral neuropathy,while also examining recent developments in this *** investigation encompassed an array of neuromodulation methods,including frequency rhythmic electrical modulated systems,dorsal root ganglion stimulation,and spinal cord *** systematic review suggests that neuromodulatory techniques may be useful in the treatment of diabetic peripheral *** the advantages of these treatments will enable physicians and other healthcare providers to offer additional options for patients with symptoms refractory to standard pharmacologic *** these efforts,we may improve quality of life and increase functional capacity in patients suffering from complications related to diabetic neuropathy.

关键词： diabetes mellitus diabetic peripheral neuropathy neuromodulation neurostimulation therapy non-pharmacological treatment pain management

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Cumulative probability and risk analysis for nd:YAG laser capsulotomy

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World Journal of Ophthalmology 2014年第3期4卷 82-86页

作者： Anna K Junk evan n dunn Anat Galor Sarah R Wellik Jesse Pelletier ninel Gregori William Feuer Ophthalmology Bascom Palmer Eye Institute University of Miami Miller School of Medicine Ophthalmology Miami VAMC Bascom Palmer Eye Institute University of Miami Miller School of Medicine

AIM: To estimate the cumulative probability of nd:YAG capsulotomy at a teaching institution and evaluate secondary risk ***: The records of all patients who underwent phacoemulsification with intraocular lens(IOL) placement between 2005-2010 were retrospectively reviewed. The cumulative probability of nd:YAG capsulotomy(capsulotomy) was calculated using KaplanMeier survival analysis and secondary risk factors were evaluated using the Cox proportional hazards regression model. RESULTS: One thousand three hundred and fifty four charts were reviewed. A total of 70 capsulotomies wereperformed. The mean follow-up was 19.4 mo(standard deviation 17 mo). The cumulative probability of capsulotomy was 4% at 1 year, 5% at 2 year, and 9% at 3 year. Multivariate analysis demonstrated an increased risk with younger age(HR = 1.03, CI 1.01-1.05, P = 0.007), placement of sulcus IOL(HR = 2.57, CI 1.32-4.99, P = 0.005), ocular trauma(HR = 2.34, CI 1.13-4.83, P = 0.02), and phacoemulsification by a more experienced surgeon(HR = 4.32, CI 1.89-9.87, P = 0.001).COnCLUSIOn: Cumulative probability of capsulotomy was lower than previously reported. Posterior capsule opacification was strongly associated with younger age and factors associated with high-risk cataract surgery. Surgeon awareness to the risk factors that correlate with posterior capsulotomy may allow for more thorough pre-operative disclosure and enhance patient satisfaction.

关键词： YAG capsulotomy Posterior capsule opacification Cataract surgery Risk factor Surgeon experience Cumulative probability Teaching institution

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The Effects of Zinc Sulfate on the in Vitro Digestibility of Feeds in Cervids

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Open Journal of Animal Sciences 2024年第3期14卷 157-167页

作者： Reese J. Thibodeaux Philip M. Urso Stanley F. Kelley Marcy M. Beverly Chris R. Stewart Ian C. dunn Gentech Diagnostics Dallas Texas USA Department of Animal Science South Dakota State University Brookings South Dakota USA School of Agricultural Sciences Sam Houston State University Huntsville Texas USA 3-S Texas Outdoors/3-S Whitetails Bedias Texas USA

The captive white-tailed deer industry has an estimated impact of 1.6 billion USD in the state of Texas alone. However, nutritional requirements for cervids are determined through research based on sheep and goats. The objective of this study was to determine the effects of zinc on differences in dry matter digestibility in vitro for white-tailed does (Odocoileus virginianus). Deer (n = 2) were ethically harvested, rumens were collected, and placed into a cooler containing warm water. Rumen contents were agitated, and fluid was filtered using cheese cloth while applying CO2. Fluid was placed into four separate incubator jars with filter bags containing a 1:1 alfalfa to coastal hay blend. Zinc doses of 0.073 mg/kg/d equivalents were added to two of the jars ( Zn), and the additional two jars received 0.00 mg/kg/d (COn). Following 48 h of incubation, in vitro true digestibility (IVTD) showed no significant differences between the control and the treatment groups. Average dry matter digested in vitro was 91.87% and 95.13%, respectively. There were no differences detected in ADF, nDF, IVTD, or OM between the treatment groups. While no detectable differences were observed in this study, this methodology did prove to be viable and functional for microbial digestion in vitro. This study can be replicated with multiple experimental units to confirm the observations of increased digestibility. Formal nutritional guidelines can be created to allow for more efficient feeding of cervids thereby reducing feed costs and continuing the growth of the captive deer industry.

关键词： Zinc IVDMD In Vitro Cervids

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Mitochondria as a therapeutic:a potential new frontier in driving the shift from tissue repair to regeneration

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Regenerative Biomaterials 2023年第1期10卷 1332-1355页

作者： evan n.Main Thaiz M.Cruz Gary L.Bowlin Department of Biomedical Engineering University of Memphis330 Engineering Technology BuildingMemphisTN 38152USA

Fibrosis,or scar tissue development,is associated with numerous pathologies and is often considered a worst-case scenario in terms of wound healing or the implantation of a *** that remains is a disorganized,densely packed and poorly vascularized bundle of connective tissue,which was once functional *** creates a significant obstacle to the restoration of tissue function or integration with any ***,it is of paramount importance in tissue engineering and regenerative medicine to emphasize regeneration,the successful recovery of native tissue function,as opposed to repair,the replacement of the native tissue(often with scar tissue).A technique dubbed‘mitochondrial transplantation’is a burgeoning field of research that shows promise in in vitro,in vivo and various clinical applications in preventing cell death,reducing inflammation,restoring cell metabolism and proper oxidative balance,among other reported ***,there is currently a lack of research regarding the potential for mitochondrial therapies within tissue engineering and regenerative ***,this review explores these promising findings and outlines the potential for mitochondrial transplantation-based therapies as a new frontier of scientific research with respect to driving regeneration in wound healing and host-biomaterial interactions,the current successes of mitochondrial transplantation that warrant this potential and the critical questions and remaining obstacles that remain in the field.

关键词： mitochondrial transplantation host-biomaterial integration biomaterials wound healing fibrosis

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Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows

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Journal of Animal Science and Biotechnology 2016年第3期7卷 423-435页

作者： Elda Dervishi Guanshi Zhang Dagnachew Hailemariam Suzana M.dunn Burim n.Ametaj Department of Agricultural Food and Nutritional ScienceUniversity of Alberta

Background： Failure to expel fetal membranes within 24 h of calving is a pathological condition defined as retained placenta（RP）. The objective of this investigation was to evaluate whether there are alterations in several selected serum variables related to innate immunity and carbohydrate and lipid metabolism that precede occurrence of RP in transition Holstein dairy ***： One hundred multiparous Holstein dairy cows were involved in the study. Blood samples were collected from the coccygeal vein during the-8 to ＋4 wks around parturition, once per week before the morning *** healthy control cows（COn） and 6 cows with RP were selected and serum samples at-8,-4, time of diagnosis of disease, and ＋4 wks relative to parturition were used for analyses. All samples were analyzed for lactate, nonesterified fatty acids（nEFA）, β-hydroxybutyrate（BHBA）, interleukin-1（IL-1）, interleukin-6（IL-6）, tumor necrosis factor（TnF）, haptoglobin（Hp）, and serum amyloid A（SAA）.Results： Cows with RP had greater concentrations of serum lactate, IL-1, IL-6, TnF, and SAA in comparison with COn cows. Intriguingly, elevated concentrations of all five variables were observed at-8 and-4 wks before the occurrence of RP compared to healthy cows. Cows with RP also had lower DMI and milk production vs COn animals; however milk composition was not affected by ***： Cows with RP showed an activated innate immunity 8 wks prior to diagnosis of disease. Overall results suggest that serum IL-1, IL- 6, and TnF, and lactate can be used as screening biomarkers to indicate cows that might have health issues during the transition period.

关键词： Innate immunity Retained placenta Serum metabolites Transition dairy cows

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Method of cells-based multiscale modeling of elastic properties of filament wound C/C-SiC including free Si and matrix porosity

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Journal of Materials Science & Technology 2019年第12期35卷 2906-2918页

作者： evan J.Pineda Marek Fassin Stefanie Reese Jaan-Willem Simon nASA Glenn Research Center 21000 Brookpark RoadMS 49/7ClevelandOH 44135United States Institute for Applied Mechanics RWTH Aachen UniversityMies-van-der-Rohe-Str.152074 AachenGermany

Three different multiscale models, based on the method of cells(generalized and high fidelity) micromechanics models were developed and used to predict the elastic properties of C/C-SiC composites. In particular, the following multiscale modeling strategies were employed: Concurrent modeling of all phases using the generalized method of cells, synergistic(two-way coupling in space) multiscale modeling with the generalized method of cells, and hierarchical(one-way coupling in space) multiscale modeling with the high fidelity generalized method of cells. The three models are validated against data from a hierarchical multiscale finite element model in the literature for a repeating unit cell of C/***, the multiscale models are used in conjunction with classical lamination theory to predict the stiffness of C/C-SiC plates manufactured via a wet filament winding and liquid silicon infiltration process recently developed by the German Aerospace Institute. Finally, un-reacted Si(or free Si) and porosity in the C matrix are included in the multiscale model, and the effect of these new phases on the stiffness and local stresses are considered.

关键词： Multiscale modeling C/C-SiC Ceramic matrix composites

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A Revised Checklist of Amphibians and Reptiles in Camiguin Sur,Misamis Oriental,Mindaanao,Philippines

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Asian Herpetological Research 2020年第1期11卷 28-43页

作者： Russell evan L·VEnTURInA Ynigo Luis C·DEL PRADO Rhim Ayyah C·KAMIR Marlon n·BALMORES Arvin C·DIESMOS Department of Biology College of ScienceDe La Salle UniversityTaft AvenueManila The Graduate School University of Santo TomasEsparaManila Mindanao State Uniersity-ligan Institute of Technology Iligan CityMindanao Herpetology Section Zoology DivisionNational Museum of Natural HistoryPhilippines

The Philippines is listed as one of the world's megadiverse countries despite its small ***,it is also on the list of global biodiversity conservation *** the threat of extinction at an all-time high,better understa nding of the archipelago's biodiversity will provide invalua ble baseline information for proper conservation *** we provide an upda ted checklist on the herpetological biodiversity of Ca miguin Sur,Misa mis Oriental,Minda nao,*** surveys and specimen collection from the municipality of Mambajao resulted in a total of 28 species(13 anurans,11 lizards,and four snakes)-all well represented by voucher *** data provides seven additional species records,upda ting the island's total amphibian and reptile species count to 57,with about half Philippine *** in the new records are three invasive alien species of amphibians:The Cane Toad Rhinella marina,the Greenhouse Frog Eleutherodatylus planirstris,and the Asiatic Painted narrowmouth Toad Kaloula pulchra.

关键词： Camiguin Sur amphibians and reptiles biodiversity Conservation

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Theoretical potential for low energy consumption phase change memory utilizing electrostatically-induced structural phase transitions in 2D materials

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npj Computational Materials 2018年第1期4卷 653-661页

作者： Daniel A.Rehn Yao Li Eric Pop evan J.Reed Department of Mechanical Engineering Stanford UniversityStanfordCA 94305USA Department of Applied Physics Stanford UniversityStanfordCA 94305USA Department of Electrical Engineering Stanford UniversityStanfordCA 94305USA Department of Materials Science and Engineering Stanford UniversityStanfordCA 94305USA

Structural phase-change materials are of great importance for applications in information storage *** driven structural phase transitions are employed in phase-change memory to achieve lower programming voltages and potentially lower energy consumption than mainstream nonvolatile memory ***,the waste heat generated by such thermal mechanisms is often not optimized,and could present a limiting factor to widespread *** potential for electrostatically driven structural phase transitions has recently been predicted and subsequently reported in some two-dimensional materials,providing an athermal mechanism to dynamically control properties of these materials in a nonvolatile fashion while achieving potentially lower energy *** this work,we employ DFT-based calculations to make theoretical comparisons of the energy required to drive electrostatically-induced and thermally-induced phase *** theoretical limits in monolayer MoTe2 and thin films of Ge_(2)Sb_(2)Te_(5),we find that the energy consumption per unit volume of the electrostatically driven phase transition in monolayer MoTe2 at room temperature is 9% of the adiabatic lower limit of the thermally driven phase transition in Ge_(2)Sb_(2)Te_(5).Furthermore,experimentally reported phase change energy consumption of Ge_(2)Sb_(2)Te_(5) is 100–10,000 times larger than the adiabatic lower limit due to waste heat flow out of the material,leaving the possibility for energy consumption in monolayer MoTe2-based devices to be orders of magnitude smaller than Ge_(2)Sb_(2)Te_(5)-based devices.

关键词： transitions phase structural

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The Correlation between n-Terminal Pro-Brain natriuretic Peptide and Diastolic Function in Asymptomatic Patients at Risk of Developing Heart Failure

The Correlation between N-Terminal Pro-Brain Natriuretic Pep...

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作者： evan Jim Gunawan 重庆医科大学

学位级别：硕士

Objective: to identify the correlation between n-terminal pro-brainnatriuretic peptide （nT-proBnP） with diastolic function in asymptomaticpatients at risk of developing heart failure, and the role of nT-proBnP inidentifying diastolic dysfunction. Methods: eighty patients （age45–70years） were selected based onhistory of hypertension, diabetes mellitus, and coronary artery *** with at least one risk factor for HF were selected in this *** were enrolled in this study from January to July2011in FirstAffiliated Hospital of Chongqing Medical University. Left ventricular （LV）diastolic function was measured by conventional Doppler and TissueDoppler imaging （TDI） echocardiography of mitral annulus. PlasmanT-proBnP concentration was measured by immunoassay. Results: There were36men and44women in this study. The mean age ofpatients was58.8years old. Hypertension was present in78/80patients（97.5%）;diabetes in32/80patients （40%）;and coronary artery disease in 25/80（31.3%）. In transmitral pulsed-wave Doppler velocity measurement,there was no significant difference of nT-proBnP between normal andimpaired relaxation （mild diastolic dysfunction）. Patients withpseudonormal filling （262.2±55.63pg/ml） and restrictive like pattern（781.5±152pg/ml） had significantly higher nT-proBnP level （p＜0.0005）.In TDI measurement, patients were grouped into3groups based on E/E’ratio ＜8（group1）, E/E’ ratio8-15（group2）, E/E’ ratio＞15（group3）. ThenT-proBnP level in group1was47.54±34.08pg/ml, group2was94.98±78.88pg/ml, and group3was781.5±152pg/ml. There was goodcorrelation between nT-proBnP and E/E’lateral （r=063;p＜0.0005）. Conclusion: nT-proBnP level increases as left ventricular diastolicfunction decreases, and there was good correlation between nT-proBnPwith E/E’ ratio. Patient with moderate-severe diastolic dysfunction hadhigher nT-proBnP level. nT-proBnP cannot be used for identification ofmild diastolic dysfunction in patient at risk of developing heart failure.

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