Cumulative probability and risk analysis for Nd:YAG laser capsulotomy

作     者：Anna K Junk Evan N Dunn Anat Galor Sarah R Wellik Jesse Pelletier Ninel Gregori William Feuer 

作者机构：Ophthalmology Bascom Palmer Eye Institute University of Miami Miller School of Medicine OphthalmologyMiami VAMC Bascom Palmer Eye Institute University of Miami Miller School of Medicine 

出 版 物：《World Journal of Ophthalmology》 (世界眼科杂志)

年 卷 期：2014年第4卷第3期

页      面：82-86页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：Supported by In part by NEI Core Center,No.P30 EY014801 Research to Prevent Blindness (RPB) Unrestricted Award and Department of Defense No.#W81XWH-09-1-0675 VA Career Development Award(CDA2) and Stanley Glaser UM to Dr.Anat Galor 

主　　题：YAG capsulotomy Posterior capsule opacification Cataract surgery Risk factor Surgeon experience Cumulative probability Teaching institution 

摘      要：AIM: To estimate the cumulative probability of Nd:YAG capsulotomy at a teaching institution and evaluate secondary risk ***: The records of all patients who underwent phacoemulsification with intraocular lens(IOL) placement between 2005-2010 were retrospectively reviewed. The cumulative probability of Nd:YAG capsulotomy(capsulotomy) was calculated using KaplanMeier survival analysis and secondary risk factors were evaluated using the Cox proportional hazards regression model. RESULTS: One thousand three hundred and fifty four charts were reviewed. A total of 70 capsulotomies wereperformed. The mean follow-up was 19.4 mo(standard deviation 17 mo). The cumulative probability of capsulotomy was 4% at 1 year, 5% at 2 year, and 9% at 3 year. Multivariate analysis demonstrated an increased risk with younger age(HR = 1.03, CI 1.01-1.05, P = 0.007), placement of sulcus IOL(HR = 2.57, CI 1.32-4.99, P = 0.005), ocular trauma(HR = 2.34, CI 1.13-4.83, P = 0.02), and phacoemulsification by a more experienced surgeon(HR = 4.32, CI 1.89-9.87, P = 0.001).CONCLUSION: Cumulative probability of capsulotomy was lower than previously reported. Posterior capsule opacification was strongly associated with younger age and factors associated with high-risk cataract surgery. Surgeon awareness to the risk factors that correlate with posterior capsulotomy may allow for more thorough pre-operative disclosure and enhance patient satisfaction.