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Storylines of family medicine Ⅲ:core principles—primary care,systems and family

Family Medicine and Community Health 2024年第S3期12卷 23-32页

作者： William B Ventres Leslie A Stone Timothy A Joslin John W Saultz Sommer Aldulaimi Paul R Gordon John C Lane eric R lee Jacob Prunuske Limor Gildenblatt Michael H Friedman Colleen T Fogarty Susan H McDaniel Tessa Rohrberg Amy Odom Family and Preventive Medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medicine Oregon Health&Science UniversityPortlandOregonUSA Family and Community Medicine University of Arizona Medical Center–South CampusTucsonArizonaUSA Family and Community Medicine University of Arizona Medical Center–University CampusTucsonArizonaUSA UAMS West Regional Campus Family Medicine Residency Program Fort SmithArkansasUSA Medical College of Wisconsin–Central Wisconsin Campus WausauWisconsinUSA Family and Community Medicine Medical College of Wisconsin–Central Wisconsin CampusWausauWisconsinUSA Family Medicine Advocate Illinois Masonic Medical CenterChicagoIllinoisUSA Family Medicine Presence Saints Mary and Elizabeth Medical CenterChicagoIllinoisUSA Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA Psychiatry and Family Medicine University of Rochester Medical CenterRochesterNew YorkUSA Family and Community Medicine University of Kansas School of Medicine-WichitaWichitaKansasUSA Sparrow/Michigan State University Family Medicine Residency Program LansingMichiganUSA

Storylines of Family Medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅲ:core principles—primary care,systems,and family’,authors address the following themes:‘Continuity of care—building therapeutic relationships over time’,‘Comprehensiveness—combining breadth and depth of scope’,‘Coordination of care—managing multiple realities’,‘Access to care—intersectional,systemic,and personal’,‘Systems theory—a core value in patient-centered care’,‘Family-oriented practice—supporting patients’health and well-being’,‘Family physician as family member’and‘Family in the exam room’.May readers develop new understandings from these essays.

关键词： individual Storyline principles

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Growth and Patterning of Pt Nanowires on Silicon Substrates

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Nano Research 2008年第2期1卷 129-137页

作者： eric P.lee Younan Xia Department of Biomedical Engineering Washington UniversitySt.LouisMissouri 63130USA

This paper describes a simple procedure for growing dense fi lms of Pt nanowires directly on silicon substrates by modifying the surface through chemical or physical *** the former,a self-assembled monolayer of(3-mercaptopropyl)-trimethoxysilane(MPTMS)is applied which can strongly bind Pt(0)nuclei to the surface through Pt S *** attached,the Pt(0)nuclei can act as catalytic sites for the growth of Pt nanowires along the〈111〉***,relief features are physically created on the surface in order to generate nucleation and binding sites for Pt(0)nuclei,due to the higher free energy associated with a rough ***,Pt nanowires have been successfully produced in well-defined patterns by scouring grooves on the silicon surface or by photochemically patterning the MPTMS monolayers with a shadow *** have also measured the electrochemical properties of these immobilized or patterned Pt *** results provide an effective route to producing dense fi lms of Pt nanowires with high surface areas for various electrochemical applications.

关键词： Platinum nanowires silicon patterned array high surface area electrochemistry

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Epidemiology of inflammatory bowel disease in South America: A systematic review

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World Journal of Gastroenterology 2019年第47期25卷 6866-6875页

作者： Sriharan Selvaratnam Santiago Gullino Lisa Shim eric lee Alice lee Sudarshan Paramsothy Rupert W Leong Department of Gastroenterology and Hepatology Macquarie University Hospital

BACKGROUND The worldwide epidemiology of inflammatory bowel disease(IBD)is rapidly *** Crohn’s disease(CD)and ulcerative colitis(UC)incidence and prevalence have been recorded in developing regions such as Asia,Africa and Eastern Europe where it was previously thought to be *** this is also the case in South America is not well *** that developing regions worldwide have increasing IBD incidence would indicate that environmental change plays a significant role in the development of *** To report the incidence,prevalence and disease characteristics of CD and UC within the South American *** A systematic review was conducted by searching published studies in major international and regional databases(MEDLINE,EMBASE and Scopus)between January 1990 and December *** considered were incidence,prevalence,phenotype,environmental and genetic factors,ethnicity and gender.A pair of independent reviewers screened and reviewed all identified *** One hundred and sixty two citations were initially retrieved with 18 studies included in this systematic *** majority of included studies were from Brazil(n=13,72%).The incidence of UC ranged from 4.3-5.3/100000 personyears whilst the incidence of CD ranged from 0.74-3.5/100000 *** ranged from 15.0-24.1/100000 inhabitants for UC and from 2.4-14.1/100000 inhabitants for *** incidence and prevalence of both UC and CD has increased significantly in Brazil over the past 21 *** was the most common disease distribution in patients with UC whilst colonic involvement was the most common distribution in *** residing in urban areas were at higher risk of developing both CD and *** The IBD burden in South America is increasing at a rate possibly even greater than other developing regions around the *** is a paucity of highquality epidemiological studies and further robust and representative data are

关键词： Inflammatory bowel disease Crohn’s disease Ulcerative colitis South America Epidemiology

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Spatial memory enhances the evacuation efficiency of virtual pedestrians under poor visibility condition

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Chinese Physics B 2018年第3期27卷 560-567页

作者： Yi Ma eric Wai Ming lee Meng Shi Richard Kwok Kit Yuen Institute for Disaster Management and Reconstruction Sichuan University Chengdu 610207 China Department of Architecture and Civil Engineering City University of Hong Kong Kowloon Hong Kong China

Spatial memory is a critical navigation support tool for disoriented evacuees during evacuation under adverse environ-mental conditions such as dark or smoky conditions. Owing to the complexity of memory, it is challenging to understand the effect of spatial memory on pedestrian evacuation quantitatively. In this study, we propose a simple method to quan- titatively represent the evacuee＇s spatial memory about the emergency exit, model the evacuation of pedestrians under the guidance of the spatial memory, and investigate the effect of the evacuee＇s spatial memory on the evacuation from theoretical and physical perspectives. The result shows that （i） a good memory can significantly assist the evacuation of pedestrians under poor visibility conditions, and the evacuation can always succeed when the degree of the memory exceeds a threshold （φ〉 0.5）; （ii） the effect of memory is superior to that of ＂follow-the-crowd＂ under the same environmental conditions; （iii） in the case of multiple exits, the difference in the degree of the memory between evacuees has a significant effect （the greater the difference, the faster the evacuation） for the evacuation under poor visibility conditions. Our study provides a new quantitative insight into the effect of spatial memory on crowd evacuation under poor visibility conditions.

关键词： crowd evacuation memory visibility social force model

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The prediction of exit choice using cumulative prospect value

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Journal of Safety Science and Resilience 2023年第1期4卷 20-25页

作者： Dongli Gao Wei Xie Ruifeng Cao eric Wai Ming lee Richard Kwok Kit Yuen Jingwen Weng Department of Architecture and Civil Engineering City University of Hong KongHong KongChina State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei230026China

Exit choice is essential for pedestrian safety and evacuation efficiency during the context of an emergency. Cumulative prospect theory is a widespread realistic decision-making theory that can transform choice outcomes and probabilities into subjective terms and integrate them as a parameter of cumulative prospect value (CPV), which determines the decision. The main contribution of this paper is the use of the CPV to predict exit choice. Furthermore, the different decision-making rules including Max, exponential(Expo), and Ratio (i.e., the three variable choice functions) were summarized and examined. This study used a confusion matrix to compare the predicted results with experimental data. Consequently, the parameters of Accuracy and F1-score showed that the predictions from Max and Expo were significantly more realistic while the results from Ratio were much more robust.

关键词： Decision-making behavior Exit choice Evacuation model Cumulative prospect value

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Study on single-group dynamics in evacuation considering pre-defined and undeclared leadership

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Journal of Safety Science and Resilience 2023年第1期4卷 52-60页

作者： Wei Xie Dongli Gao Ruifeng Cao eric Wai Ming lee Richard Kwok Kit Yuen Jingwen Weng Department of Architecture and Civil Engineering City University of Hong KongKowloon TongHong KongChina State Key Laboratory of Fire Science University of Science and Technology of ChinaHefei 230026China

Grouping is a common phenomenon that occurs *** leader-follower relationship inside groups has often been qualitatively characterized in previous models using simple ***,a general method is lacking to quantitatively explain leadership in an evacuating *** understand the evolution of single-group dynamics throughout an evacuation,we developed an extended social force model integrated with a group force.A series of single-group evacuations from a room were *** information-theoretic method,transfer entropy(TE),was applied to detect predefined and undeclared leadership among *** results showed that the predefined leader was correctly detected by TE,suggesting its capability in measuring leadership based on time series of evacuees’movement information(e.g.,velocity and acceleration).When evacuees were grouped together,TE was higher than when they were *** presented a monotonically increasing cumulative influence curve over the investigated period,whereas followers showed a diminishing *** found that leadership emergence correlated with evacuees’spatial *** individual located in the foremost part of the group was most likely to become a leader of those in the rear,which concurred with the experimental *** observed how a large group split into smaller ones with undeclared leadership during *** observations were quantitatively verified by TE *** study provides novel insights into quantifying leadership and understanding single-group dynamics during evacuations.

关键词： Evacuation Social force model Group behavior Leadership Transfer entropy

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A Phonetic Study of the Tones in Meixian Hakka

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客家研究辑刊 2010年第2期 151-158页

作者： Wai - Sum lee eric Zee Phonetics Lab Department of Chinese Translation and Linguistics City University of Hong Kong

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Anthracycline-induced cardiotoxicity:A case report and review of literature

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World Journal of Cardiology 2021年第1期13卷 28-37页

作者： Esther G Chong eric H lee Reena Sail Laura Denham Gayathri Nagaraj Chung-Tsen Hsueh Department of Medicine Loma Linda UniversityLoma LindaCA 92350United States Department of Hematology/Oncology Compassionate Cancer Care Medical GroupFountain ValleyCA 92708United States Department of Hematology/Oncology Scripps MD Anderson Cancer CenterSan DiegoCA 92121United States Department of Pathology and Human Anatomy Loma Linda UniversityLoma LindaCA 92350United States Division of Medical Oncology and Hematology Department of MedicineLoma Linda UniversityLoma LindaCA 92350United States

BACKGROUND Doxorubicin and other anthracycline derivatives inhibit topoisomerase II and is an important class of cytotoxic chemotherapy in cancer *** use of anthracycline is limited by dose-dependent cardiotoxicity,which may manifest initially as asymptomatic cardiac dysfunction with subsequent progression to congestive heart *** baseline assessment and periodic monitoring of cardiac function for patients receiving anthracycline agents,there are unmet needs in prediction and prevention of anthracycline-induced cardiotoxicity(AIC).CASE SUMMARY A 35-year-old African American female was found to have a 9-cm high-grade osteosarcoma of right femur and normal baseline cardiac function with left ventricular ejection fraction of approximately 60%-70%determined by transthoracic and dobutamine stress *** underwent perioperative doxorubicin and cisplatin chemotherapy with 3 cycles before surgery and 3 cycles after surgery,and received a total of 450 mg/m2 doxorubicin at the end of her treatment *** was evaluated regularly during chemotherapy without any cardiac or respiratory *** two months after her last chemotherapy,the patient presented to the emergency department with dyspnea for one week and was intubated for acute hypoxic respiratory *** showed an ejection fraction of 5%-10%with severe biventricular *** attempts to optimize cardiac function,the patient’s hemodynamic status continued to decline,and resuscitation was not successful on the seventh day of *** autopsy showed no evidence of osteosarcoma,and the likely cause of death was cardiac failure with the evidence of pulmonary congestion,liver congestion,and multiple body cavity *** We present a case of 35-year-old African American female developing cardiogenic shock shortly after receiving a cumulative dose of 450 mg/m2 doxorubicin over 9 *** monitoring and management of patients receivin

关键词： Anthracycline Cardiotoxicity Doxorubicin Troponin Brain natriuretic peptide Case report

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Description of a novel robotic early post-prostatectomy anastomotic repair technique and institutional outcomes

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Asian Journal of Urology 2024年第3期11卷 366-372页

作者： David Strauss eric Cho Matthew Loecher Matthew lee Daniel Eun Department of Urology Lewis Katz School of MedicineTemple UniversityPhiladelphiaPAUSA

Objective:A vesicourethral anastomotic leak(VUAL)is a known complication following robotic-assisted radical *** natural history of a VUAL has been well described and is frequently managed with prolonged *** increasing emphasis on patient reported outcomes,catheter duration and VUAL are associated with significant short-term quality of life *** aimed to present a case series of our robotic early post-prostatectomy anastomotic repair technique,defined as revision within 6 weeks from index ***:A single institution prospective database identified eleven patients with a VUAL from July 2016 to October 2022 who underwent robotic early post-prostatectomy anastomotic repair by a single *** were diagnosed with a VUAL on pre-operative CT urogram or CT/fluoroscopic *** primary outcome was resolution of the anastomotic leak,defined as no contrast extravasation on post-operative *** outcomes included post-repair catheter duration and continence on the last follow-up defined as pad(s)per ***:The mean time to intervention after robotic-assisted radical prostatectomy was 21 *** of the eleven(72.7%)patients had no evidence of extravasation on postrepair *** range from intervention to first cystogram was 7e20 *** median catheter duration for those with successful intervention was 10 *** median catheter duration for those with the leak on initial post-operative cystogram was 20 *** a mean follow-up time of 25 months,eight(72.7%)patients reported using no pads per day,and three(27.3%)patients reported one pad per ***:Management of a VUAL has traditionally relied on prolonged catheter drainage and the tincture of *** the role of robotic reconstruction has been shown to be a viable modality for management of bladder neck contracture,it is important to reconsider prior dogmas of urologic *** case series suggests that an early repair is saf

关键词： Minimallyinvasive surgery Vesicourethral anastomotic leak Robotic-assisted laparoscopic reconstruction

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Development of an agent-based indoor evacuation model for local fire risks analysis

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Journal of Safety Science and Resilience 2023年第1期4卷 75-92页

作者： Rui Feng Cao eric Wai Ming lee Wei Xie Dong Li Gao Qian Chen Anthony Chun Yin Yuen Guan Heng Yeoh Richard-Kwok-Kit Yuen Department of Architecture and Civil Engineering City University of Hong KongKowloon TongHong KongChina School of Mechanical and Manufacturing Engineering University of New South WalesSydneyNSW 2052Australia

Evidence suggests that in the event of a fire accident, a certain number of building occupants escape through smoke-filled environments. Consequently, evaluating the corresponding evacuation performance under such life-threatening conditions is important for advancing fire safety analyses. This study aimed to develop a fire-integrated evacuation model to consider the effects of spreading fire hazards (i.e., radiation, temperature, toxic gas, visibility) on evacuees in a room fire evacuation scenario. Furthermore, a novel quantitative approach was introduced to evaluate evacuees’ local fire risks and stress levels according to their egress paths. The escape characteristics at various stages of fire development were studied as well. The results demonstrate that evacuation performance varies considerably depending on the severity of evacuees’ confronted fire hazard conditions, which emphasizes the importance of minimizing the pre-evacuation time in fire evacuation emergencies.

关键词： Fire emergency Indoor evacuation modeling Local fire risks Evacuation dynamics

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