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Steel slag carbonation in a flow-through reactor system:The role of fluid-flux

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journal of Environmental Sciences 2015年第1期27卷 266-275页

作者： eleanor j.Berryman anthony E.Williams-jones Artashes A.Migdisov Department of Earth and Planetary Sciences McGill University Technische Universitat Berlin Los Alamos National Laboratory

Steel production is currently the largest industrial source of atmospheric CO2. As annual steel production continues to grow, the need for effective methods of reducing its carbon footprint increases correspondingly. The carbonation of the calcium-bearing phases in steel slag generated during basic oxygen furnace（BOF） steel production, in particular its major constituent, larnite {Ca2SiO4}, which is a structural analogue of olivine {（MgFe）2SiO4}, the main mineral subjected to natural carbonation in peridotites, offers the potential to offset some of these emissions. However, the controls on the nature and efficiency of steel slag carbonation are yet to be completely understood. Experiments were conducted exposing steel slag grains to a CO2–H2O mixture in both batch and flow-through reactors to investigate the impact of temperature, fluid flux, and reaction gradient on the dissolution and carbonation of steel slag. The results of these experiments show that dissolution and carbonation of BOF steel slag are more efficient in a flow-through reactor than in the batch reactors used in most previous studies. Moreover, they show that fluid flux needs to be optimized in addition to grain size, pressure, and temperature, in order to maximize the efficiency of carbonation. Based on these results, a two-stage reactor consisting of a high and a low fluid-flux chamber is proposed for CO2 sequestration by steel slag carbonation,allowing dissolution of the slag and precipitation of calcium carbonate to occur within a single flow-through system.

关键词： CO2sequestration Steel slag carbonation Flow-through reactor Fluid flux

A quasi-crystal model of collagen microstructure based on SHG microscopy

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Chinese Optics Letters 2010年第2期8卷 213-216页

作者： Pu Xu eleanor Kable Colin j. R. Sheppard Guy Cox Australian Key Centre for Microscopy and MicroanMysis University of Sydney NSW 2006 Australia Division of Bioengineering National University of Singapore Singapore 117576 Key Laboratory of Ecophysics Department of Physics Shihezi University Shihezi 832000 China

Second harmonic generation （SHG） results from molecules which are polarized by an external electric field often provided by an intense laser beam. The polarizability depends on firstly the intrinsic structural properties of the substance and hence the second-order nonlinear susceptibility, and secondly the intensity and polarization direction of the incident light. The polarization characteristics of the beam are therefore of interest. In this letter, we discuss some considerations in SHG microscopy of collagen when the incoming beam is circularly polarized, and present some supporting results as well as a numerical analysis. We propose a quasi-crystal model of collagen microstructure in an effort to further our understanding on this protein.

关键词： Collagen Electric fields Harmonic generation Nonlinear optics Numerical analysis Polarization Quasicrystals

Immunomodulation as a neuroprotective strategy after spinal cord injury

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Neural Regeneration Research 2018年第3期13卷 423-424页

作者： Susana Monteiro antónio j. Salgado Nuno A. Silva Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoCampus de GualtarBragaPortugal ICVS/3B's-PT Government Associate Laboratory Braga/GuimaraesPortugal

The initial trauma to the spinal cord is just the starting point for a cascade of endogenous events that will collectively determine the injury extension. These secondary events include, but are not limited to： glutamate excitoxicity, induction of apoptotic pathways, ionic imbalances and the development of a strong and dysfunctional inflammatory response. The secondary injury is associated to an aggravation of neuronal damage increasing the extent of neurological deficits （Ek et al., 2010）.

关键词： Immunomodulation as a neuroprotective strategy after spinal cord injury SCI

Combinatorial therapies for spinal cord injury: strategies to induce regeneration

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Neural Regeneration Research 2019年第1期14卷 69-71页

作者： Eduardo D.Gomes Nuno A.Silva antónio j. Salgado Life and Health Sciences Research Institute (ICVS) School of Medicine University of Minho Campus de Gualtar ICVS/3B’s–PT Government Associate Laboratory

Spinal cord injury(SCI)is a condition without treatment,mainly characterized by the loss of motor and sensory function below the level of *** is accompanied by several complications such as cardiac and respiratory compromise,and often patients present psychological ailments associated with the drastic alteration of their normal *** pathophysiology derives from a massive damage to the spinal cord tissue,which is propagated

关键词：损害绳索新生治疗感觉功能生活方式星形细胞并发症

Small dams/reservoirs site location analysis in a semi-arid region of Mozambique

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International Soil and Water Conservation Research 2021年第3期9卷 381-393页

作者： antònio dos Anjos Luís Pedro Cabral Department of GIS and Regional Planning Universidade Catdlica de MozambiqueBeiraSofalaMozambique NOVA Information Management School(NOVA IMS) Universidade Nova de Lisboa1070-312LisboaPortugal

The water crisis is one of the biggest human problems in developing countries,especially in semi-arid regions where it can form an obstacle to irrigation and cultivation,cattle raising and people's *** construction of small dams/reservoirs are a possible solution to remediate this *** infrastructures must be located in suitable areas to be *** study aimed to find the most suitable locations for small dams/reservoirs in the Tete province region,Mozambique,which has a pronounced water deficit A Geographical Information System(GIS)based approach was used to implement a multicriteria evaluation(MCE)analysis through an Analytic Hierarchical Process(AHP),which included local experts’*** main categories of suitability were identified:"Not suitable”(15%of total area),"Modestly suitable"(78%),and“Suitable"(7%).We found that 35 of the 38(92%)abandoned small dams/reservoirs were in areas classified as“Modestly suitable”confirming the robustness of our *** also found that most of the dams/reservoirs currently operating(78%)and planned(73%)are in modestly suitable *** finding suggests that the decision to construct dams/reservoirs may not have considered the most critical suitability factors identified in this *** data and/or additional criteria are required for the full understanding of finding out why so many dams/reservoirs failed before building new ones to address the population’s water needs in the region.

关键词： Water scarcity Multi-criteria evaluation Geographic information systems Remote sensing Mozambique

Hydro-wind Optimal Operation for joint Bidding in Day-ahead Market: Storage Efficiency and Impact of Wind Forecasting Uncertainty

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journal of Modern Power Systems and Clean Energy 2020年第1期8卷 142-149页

作者： antónio Cerejo Sílvio j.P.S.Mariano Pedro M.S.Carvalho Maria R.A.Calado Technical-Scientific Unity of Electrical and Industrial Engineering Polytechnic Institute of Castelo BrancoAvenida do Empresário6000-767 Castelo BrancoPortugal Department of Electromechanical Engineering University of Beira Interior and Instituto de TelecomunicacoesCalcada Fonte do Lameiro6201-001 CovilhaPortugal Department of Electrical and Computer Engineering Instituto Superior Técnicoand INESC-IDUniversity of LisbonAv.Rovisco Pais1049-001 LisbonPortuga

Wind power production is *** imbalance between committed and delivered energy in pool markets leads to the increase of system costs,which must be incurred by defaulting producers,thereby decreasing their *** avoid this situation,wind producers can submit their bids together with hydro *** the mismatches between the predicted and supplied wind power can be used by hydro producers,turbining or pumping such differences when *** study formulates the problem of hydro-wind production optimization in operation contexts of pool *** problem is solved for a simple three-reservoir cascade case to discuss optimization *** results show a depreciation in optimal revenues from hydro power when wind forecasting is *** depreciation is caused by an asymmetry in optimal revenues from positive and negative wind power *** problem of neutralizing the effect of forecasting uncertainty is subsequently formulated and solved for the three-reservoir *** results are discussed to conclude the impacts of uncertainty on joint bidding in pool market contexts.

关键词： Optimization hydro power wind power uncertainty joint bidding pool market

Evaluation of markers of outcome in realworld treatment of diabetic macular edema

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Eye and Vision 2018年第1期5卷 240-249页

作者： antónio Campos Elisa j Campos Anália do Carmo Francisco Caramelo joão Martins joão P Sousa antónio Francisco Ambrósio Rufino Silva Coimbra Institute for Clinical and Biomedical Research(iCbr) Faculty of MedicineUniversity of CoimbraAzinhaga de Santa CombaCelas3000-548 CoimbraPortugal CNC.iCbr Consortium University of CoimbraCoimbraPortugal Department of Ophthalmology Leiria HospitalLeiriaPortugal Clinical Pathology Department Centro Hospitalar Universitário de Coimbra(CHUC)CoimbraPortugal Laboratory of Biostatistics and Medical Informatics Faculty of MedicineUniversity of CoimbraCoimbraPortugal Medical Sciences Department Faculty of Health SciencesUniversity of Beira InteriorCovilhãPortugal Association for Innovation and Biomedical Research on Light and Image(AIBILI) CoimbraPortugal Department of Ophthalmology Centro Hospitalar Universitário de Coimbra(CHUC)CoimbraPortugal

Objective:To evaluate short-term markers of outcome in diabetic macular edema(DME).Methods:Prospective interventional case series included 122 eyes of 122 patients with recently diagnosed *** were treated with a 3-monthly loading dose of ranibizumab or aflibercept and pro re nata *** enhanced deep imaging SD-OCT high resolution scans were used to measure subfoveal choroidal thickness(SFCT)and central retinal thickness(CRT).Anatomic(10%CRT decrease)and functional responses(best corrected visual acuity,BCVA gain≥5 letters)were assessed at 3 months and 6 months using univariate and multivariate *** tested were gender,duration of diabetes,HbA1c,hypertension,CRT,SFCT,BCVA,ellipsoid zone(EZ)status,subfoveal neuroretinal detachment(SND),anti-VEGF used and laser naivety.A logistic regression model was applied to find independent markers ***:BCVA increased,CRT and SFCT decreased at 3 months and 6 *** metabolic control(p=0.003),intact baseline EZ(p=0.030),EZ re-grading at 3 M(p<0.001)and laser naivety(p=0.001)were associated with better functional *** multivariate linear regression model showed that baseline SND and CRT are predictors of anatomic response,while lower baseline BCVA and intact EZ are predictors of functional ***:The presence of SND predicts anatomic response only,while an intact EZ is critical to achieve a good functional outcome in DME.

关键词： Diabetic macular edema Outcome factors Spectral-domain optical coherence tomography antivascular endothelial growth factor Laser

Measuring project performance by applying social network analyses

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International journal of Innovation Studies 2021年第2期5卷 35-55页

作者： Marco Nunes antónio Abreu jelena Bagnjuk jörn Tiedtke Industrial Engineering Department of University of Beira Interior 6201-001CovilhaPortugal Mechanical Engineering Department of Polytechnic Institute of Lisbon 1959-007LisbonPortugal CTS Uninova 2829-516CaparicaPortugal Project Management Department UKE(University Medical Center Hamburg-Eppendorf)Martinistraße 5220251HamburgGermany Project Management Department Hays&Tetra Pak Brandstwiete 120457HamburgGermany

It is often argued that the core of organizational success is efficient *** authors even posit that efficient collaboration is more important to organizational innovation and performance than individual skills or ***,the lack of efficient models to manage collaboration properly is a major constraint for organizations to profit from internal and external collaborative ***,much of the collaboration in organizations occurs through virtual network channels,such as e-mail,Yammer,jabber,Microsoft Teams,Skype,and *** are even more important in situations where different time zones and even threats of a pandemic constrain face-to-face human *** work introduces a multidisciplinary heuristic model developed based on project risk management and social network analysis centrality metrics graph-theory to quantitatively measure dynamic organizational collaboration in the project environment.A case study illustrates the proposed model’s implementation and application in a real virtual project organizational *** major benefit of applying this proposed model is that it enables organizations to quantitatively measure different collaborative,organizational,and dynamic behavioral patterns,which can later correlate with organizational *** model analyzes three collaborative project dimensions:network collaboration cohesion evolution,network collaboration degree evolution,and network team set variability *** provides organizations an innovative approach to understand and manage possible collaborative project risks that may emerge as projects are *** can use the proposed model to identify projects’critical success factors by comparing successful and unsuccessful delivered projects’dynamic behaviors if a substantial number of both project types are *** proposed model also enables organizations to make decisions with more information regarding the support for changes i

关键词： Project risk management Social network analysis Project performance Project outcome Project critical success factor Sustainability Innovation

From regenerative strategies to pharmacological approaches:can we fine-tune treatment for Parkinson's disease?

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Neural Regeneration Research 2022年第5期17卷 933-936页

作者： Rita Caridade Silva Helena Sofia Domingues antónio j.Salgado Fábio G.Teixeira Life and Health Sciences Research Institute(ICVS) School of MedicineUniversity of MinhoBragaPortugal ICVS/3B’s Associate Lab PT Government Associated LabBraga/GuimarãesPortugal

Parkinson's disease is the second most prevalent neurodegenerative disorder ***,it is characterized by severe motor complications caused by progressive degeneration of dopaminergic *** treatment is focused on mitigating the symptoms through the administration of levodopa,rather than on preventing dopaminergic neuronal ***,the use and development of neuroprotective/disease-modifying strategies is an absolute need that can lead to promising gains on translational research of Parkinson's *** instance,N-acetylcysteine,a natural compound with strong antioxidant effects,has been shown to modulate oxidative stress,preventing dopamine-induced cell *** the evidence of neuroprotective and modulatory effects of this drug,as far as we know,it does not induce per se any regenerative ***,it would be of interest to combine the latter with innovative therapies that induce dopaminergic neurons repair or even differentiation,as stem cell-based *** cells secretome has been proposed as a promising therapeutic approach for Parkinson's disease,given its ability to modulate cell viability/preservation of dopaminergic *** approach represents a shift in the paradigm,showing that cell-transplantation free therapies based on the use of stem cells secretome may represent a potential alternative for regenerative medicine of Parkinson's ***,in this review,we address the current understanding of the potential combination of stem cell free-based strategies and neuroprotective/disease-modifying strategies as a new paradigm for the treatment of central nervous system neurodegenerative diseases,like Parkinson's disease.

关键词： disease-modifying strategies mesenchymal stem cells N-acetylcysteine neuroprotection Parkinson's disease stem cells secretome