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Insect Science 2018年第6期25卷 1102-1107页

作者： Stanislas Talaga Alain Dejean clémence Mouza Yves Dumont Céline Leroy lnsUtut Pasteur de la Guyane Unitéd'Entomologie MédicaleCayenne cedexFrance CNRS UMR EcoFoGAgroParisTechCiradINRAUniversitédes AntillesUniversitéde GuyaneKourouFrance CNRS INPTUPSEcolabUniversitéde ToulouseToulouseFrance AMAP CIRADCNRSINRAIRDUniversit6MontpellierMontpellierFrance

Interspecific competition with native species during biological invasions can sometimes limit alien *** aimed to determine the potential ecological effects of Limatus durhamii Theobald 1901,a native Neotropical mosquito (Diptera:Culicidae) species,on the invasive species Aedes (Stegomyia)aegypti (Linnaeus 1762)that breeds in the same artificial water *** time and adult dry mass were measured in 3 rearing conditions:control (a single larva),intraspecific competition (2 conspecific larvae),and interspecific competition (2 heterospecific larvae).Food was provided ad libitum to eliminate exploitative *** ***,development time was not affected by interspecific interference competition (nonsignificant differences with the control)and the adult dry mass was significantly higher,meaning that individual fitness likely ***,because previous studies showed longer development time and lighter adults during competition with other invasive mosquitoes,it is likely that *** can express a different phenotype depending on the competing *** similar pattern found for *** females and the nonsignificant difference with the control for males explain in part why this species can compete with ***.

关键词： Aedes aegypti increased fitness interference competition Limatus durhamii phenotypic plasticity resistance to invasion

Role of nickel-regulated small RNA in modulation of Helicobacter pylori virulence factors

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World Journal of clinical Cases 2022年第31期10卷 11283-11291页

作者： Fabrício Freire de Melo Hanna Santos Marques Fabian Fellipe Bueno Lemos Marcel Silva Luz Samuel Luca Rocha Pinheiro Lorena Sousa de Carvalho cláudio Lima Souza Márcio Vasconcelos Oliveira Institution Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094Brazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900Brazil

Helicobacter pylori(***)is a Gram-negative bacterium that infects about half of the world's *** infection prevails by several mechanisms of adaptation of the bacteria and by its virulence factors including the cytotoxin associated antigen A(CagA).CagA is an oncoprotein that is the protagonist of gastric carcinogenesis associated with prolonged *** *** this sense,small regulatory RNAs(sRNAs)are important macromolecules capable of inhibiting and activating gene *** function allows sRNAs to act in adjusting to unstable environmental conditions and in responding to cellular stresses in bacterial *** discoveries have shown that nickelregulated small RNA(NikS)is a post-transcriptional regulator of virulence properties of ***,including the oncoprotein ***,high concentrations of nickel cause the reduction of NikS expression and consequently this increases the levels of *** addition,NikS expression appears to be lower in clinical isolates from patients with gastric cancer when compared to patients *** that in mind,this minireview approaches,in an accessible way,the most important and current aspects about the role of NikS in the control of virulence factors of *** and the potential clinical repercussions of this modulation.

关键词： Helicobacter pylori Small regulatory RNAs Nickel-regulated small RNA Virulence factors Cytotoxin associated antigen A Gastric cancer

Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

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Journal of Sport and Health Science 2024年第4期13卷 548-558,F0003页

作者： Hugo de Luca Correa Lysleine Alves Deus Dahan da Cunha Nascimento Nicholas Rolnick Rodrigo Vanerson Passos Neves Andrea Lucena Reis Thais Branquinho de Araujo Carmen Tzanno-Martins Fernanda Silveira Tavares Luiz Sinesio Silva Neto claudio Avelino Rodrigues Santos Paolo Lucas Rodrigues-Silva Fernando Honorato Souza Vitoria Marra da Motta Vilalva Mestrinho Rafael Lavarini dos Santos Rosangela Vieira Andrade Jonato Prestes Thiago dos Santos Rosa Post-graduate Program of Physical Education Catholic University of BrasıliaBrasılia 71966-700Brazil The Human Performance Mechanic Lehman CollegeNew YorkNY 10011USA clinical Group Home Dialysis Center and Renalclass Sao Paulo 01239-040Brazil Department of Medicine Catholic University of BrasıliaBrasılia 71966-700Brazil Faculty of Medicine Federal University of TocantinsTocantins 77001-090Brazil Embrapa Genetic Resources and Biotechnology Brasılia 70770-917Brazil Graduate Program of Genomic Sciences and Biotechnology Brasılia 71966-700Brazil

Background:Hemodialysis(HD) per se is a risk factor for *** the growing body of evidence on blood-flow restriction(BFR) exercise in HD patients,identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training *** aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise(RE) with BFR on this ***:Two hundred and six HD patients volunteered for this study(all with a glomerular filtration rate of clusion pressure during 50 min sessions of HD(intradialytic exercise).RE repetitions included concentric and eccentric lifting phases(each lasting 2 s) and were supervised by a strength and conditioning ***:Several variables were associated with elevated levels of D-dimer,including higher blood glucose,citrate use,recent cardiovascular events,recent intercurrents,higher inflammatory status,catheter as vascular access,older patients(>70 years old),and HD ***,RE+BFR significantly increases D-dimer after 4 *** with borderline baseline D-dimer levels(400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range(≥500 ng/mL).Conclusion:These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE+BFR.D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE+BFR.

关键词： Blood-flow restriction Chronic kidney disease Coagulation Hemodialysis Vascular occlusion exercises

Convulsive Seizures Revealing Hashimoto’s Encephalopathy

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World Journal of Neuroscience 2022年第3期12卷 105-111页

作者： Djikoldinguem Marschall Mouandilmadji Coudjou Josue Dieu-donne Ghislain de Chacus Kawtar Jamil Maureen Vanessa Ngo Biem Pape Amadou Niane Fatou Bintou Thiam Mame Pathé Diakhate Nafy Ndiaye Abdoulaye Leye Department of Internal Medicine/Endocrinology-Diabetology and Nutrition Pikine National Hospital Center Dakar Senegal Hann Maristes Health Center Dakar Senegal Neuroscience clinic Ibrahima Pierre Ndiaye National University Hospital of Fann Dakar Senegal

Introduction: Hashimoto encephalopathy (HE) is an autoimmune disease with different neurological and psychiatric characteristics. It is associated with increased thyroperoxidase autoantibodies. The diagnosis of HE is clinical and involves the detection of serum thyroperoxidase (TPO) antibodies and the exclusion of other etiologies. A clinical response to corticosteroid therapy supports the diagnosis. We report a case of HE revealed by convulsive seizures and cognitive and behavioral disorders. Observation: She is a 7-year-old child followed in a neurology unit for convulsive seizures for one year. clinical examination performed in the endocrinology unit later found tachycardia without goiter, behavioral disorders, difficulties to concentrate as well as psychomotor agitation. Biological work up revealed subclinical hypothyroidism, positive anti-TPO antibodies with normal thyroid ultrasound and brain MRI. The cerebrospinal fluid was clear, normotensive and absence of pleocytosis. The sleep-wake electroencephalogram was well organized for her age with a paroxysmal discharge in the left parieto-temporal region. Based on these clinical, biological and morphological data, the diagnosis of HE was retained. Corticosteroid therapy with prednisone at 1 mg/kg/day was initiated for 6 weeks while reducing the dose progressively. There was a good clinical and biological progress under treatment. Conclusion: Hashimoto’s encephalopathy is a rare, but probably unrecognized entity. Over the past decades, knowledge about thyroid, brain, immunity interactions has increased. This indicates the importance of a multidisciplinary approach of endocrinologists, neurologists, psychiatrists and pediatricians for early recognition and treatment.

关键词： Hypothyroidism Encephalopathy Hashimoto’s Thyroiditis Antithyroperoxidase Antibody

Assessment of resting energy expenditure in patients with cirrhosis

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World Journal of Hepatology 2022年第4期14卷 802-811页

作者： Shaiane Ferreira cláudio Augusto Marroni Jessica Taina Stein Roberta Rayn Ana Cristhina Henz Natália P Schmidt Randhall B Carteri Sabrina Alves Fernandes Postgraduate Program in Hepatology Federal University of Health Sciences of Porto Alegre(UFCSPA)Porto Alegre 90050-170Brazil Department of Nutrition Centro Universitário Metodista-IPAPorto Alegre 90420-060Brazil Department of Health and Behavior Catholic University of PelotasPelotas 96015-560Brazil

BACKGROUND Malnutrition affects 20%to 50%of patients with *** may be associated with serious complications and has a direct impact on *** energy expenditure(REE)is an important parameter to guide the optimization of therapy and recovery of nutritional status in patients with ***,the REE of patients with cirrhosis is still unclear,casting doubt upon the optimal nutritional management *** To identify the best method that predicts the REE of cirrhotic patients,using indirect calorimetry(IC)as the gold *** An observational study was performed on 90 patients with *** was assessed by IC,bioelectrical impedance analysis(BIA),and predictive formulas,which were compared using Bland-Altman plots and the Student’s *** REE values measured by IC(1607.72±257.4 kcal)differed significantly from those determined by all other methods(BIA:1790.48±352.1 kcal;Harris&Benedict equation:2373.54±254.9 kcal;IOM equation:1648.95±185.6 kcal;Cunningham equation:1764.29±246.2 kcal),except the Food and Agriculture Organization of the United Nations,World Health Organization,and United Nations University(FAO/WHO/UNU)(1616.07±214.6 kcal)and McArdle(1611.30±241.8 kcal)*** found no significant association when comparing IC and 24-h dietary recall among different Child-Pugh classes of *** The IOM and FAO/WHO/UNU equations have the best agreement with the *** results indicate a possibility of different tools for the clinical practice on cirrhotic patients.

关键词： Liver cirrhosis Calorimetry Indirect Energy metabolism Malnutrition

Preparation and Characterization of Bonded Stationary Phase Containing Monoaza Crown Ether for High-Performance Liquid Chromatography

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Chinese Chemical Letters 1997年第6期8卷 519-522页

作者： You, JM Xie, GH Wang, HE Wang, GJ Zhou, cl Su, JX CHINESE ACAD SCI LANZHOU INST CHEM PHYSLANZHOU 730000PEOPLES R CHINA SHANDONG UNIV DEPT CHEMJINAN 273165PEOPLES R CHINA

Silica gel bonded stationary phases containing monoaza crown ether was synthesized via a series of solid-liquid phase reactions. The bonded molecular structure was characterized by chemical and instrumental analyses. The bonded stationary phase was provided with complexing ability with copper ion as well as hydrophobic property. The chromatographic retention behaviours of some substituted polar phenol derivatives, organic acids and bases on the bonded stationary phase were studied using methanol and/or aqueous solution of dibasic potassium phosphate buffer as mobile phase. When copper ion was added to the mobile phase at pH 5.4, the retention of substituted phenols became strong.

关键词： INORGANIC ANIONS CATIONS

DEVELOPMENT　OF　Sr_0．69La_0．31F_2．31＋SrSSOLID　ELECTROLYTE　SENSOR　AND　ITS　APPLICATION

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中国有色金属学会会刊：英文版 1995年第1期5卷 49-52页

作者： ZHAI, YC MA, P TIAN, YW XIAO, F JI, cl NORTHEASTERN UNIV SHENYANG 110006PEOPLES R CHINA

ＤＥＶＥＬＯＰＭＥＮＴＯＦＳｒ０．６９Ｌａ０．３１Ｆ２．３１＋ＳｒＳＳＯＬＩＤＥＬＥＣＴＲＯＬＹＴＥＳＥＮＳＯＲＡＮＤＩＴＳＡＰＰＬＩＣＡＴＩＯＮＺｈａｉ；ＹｕｃｈｕｎＭａ；ＰｉｎｇＴｉａｎ；ＹａｎｗｅｎＸｉａｏ；Ｆ... 详细信息

ＤＥＶＥＬＯＰＭＥＮＴＯＦＳｒ０．６９Ｌａ０．３１Ｆ２．３１＋ＳｒＳＳＯＬＩＤＥＬＥＣＴＲＯＬＹＴＥＳＥＮＳＯＲＡＮＤＩＴＳＡＰＰＬＩＣＡＴＩＯＮＺｈａｉ；ＹｕｃｈｕｎＭａ；ＰｉｎｇＴｉａｎ；ＹａｎｗｅｎＸｉａｏ；ＦｅｉＪｉ；Ｃｈｕｎ?..

关键词： solid electrolyte electrochemical sensor sulphur activity

Evaluation of parasitemia by qPCR in patients with chronic Chagas disease treated with benznidazole

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Asian Pacific Journal of Tropical Medicine 2023年第12期16卷 565-572页

作者： Tycha Bianca Sabaini Pavan Eros Antônio de Almeida Rodrigo Gonçalves de Lima Jamiro da Silva Wanderley Luiz cláudio Martins Sandra Cecília Botelho Costa Gláucia Elisete Barbosa Marcon Departamento de clínica Médica Faculdade de Ciências MédicasUniversidade Estadual de Campinas(Unicamp)CampinasSão PauloBrasil Fundação Oswaldo Cruz Fiocruz Mato Grosso do SulCampo GrandeMSBrasil

Objective:To evaluate parasitemia by qPCR in patients undergoing etiological treatment and followed in a Brazilian reference ***:Parasite load was quantified by qPCR in 32 participants with chronic Chagas disease who were treated with *** analyses were performed before and after the treatment and parasite loads were compared prior and 12/18 months post the ***:Thirty-two participants were recruited and treated with benznidazole,and 20 were *** events(AE)were observed in 22 out of 29 participants that had safety data(76%),and dermatological alterations were the most frequently observed *** the 20 participants analyzed,13 and 7 completed 12 and 18 months follow-up after the treatment,respectively.12 Months after the final treatment,Trypanosoma cruzi was detectable in 3 patients by qPCR;18 months after the final treatment,Trypanosoma cruzi was detectable per qPCR in 4 of the 7 ***,between 12 and 18 months,7 participants of the 20 initial follow-up cases showed positive qPCR,indicating treatment ***:qPCR can be used as an alternative method for evaluating the effectiveness of the etiological treatment of CD,and can be applied to analyze early therapeutic *** study showed that benznidazole therapy had limited effectiveness in treating chronic CD patients,thus emphasizing the importance of conducting continued research for developing more effective therapies and diagnosis for CD.

关键词： Trypanosoma cruzi Chagas disease Antitrypanosomal therapy Benznidazole qPCR Therapeutic failure

Influence of low energy ballistic electron on the transmittance properties of Au/Si interface studied by ballistic-electron-emission microscope

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Chinese Science Bulletin 1997年第15期42卷 1282-1286页

作者： Qiu, XH Shang, GY Wang, C Wang, NX Bai, cl CHINESE ACAD SCI INST CHEMBEIJING 100080PEOPLES R CHINA

METAL/SEMICONDUCTOR interfaces have attracted widespread interest for a long time. Tradi-tional techniques, such as photoelectric and capacitance-voltage method, are proved to beeffective in determining some electrical properties of interfaces. However, they usually providespatial average results over macroscopic dimensions. With the rapid development of microelec-tronics, there is an urgent need to investigate electrical properties of the M/S interfaces on ananometer scale.

关键词： Au/Si interface ballistic-electron-emission microscopy transmittance probability.

Conformational Analysis of Two Diosgenyl Saponins

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Chinese Chemical Letters 1997年第9期8卷 785-788页

作者： Liu, MZ Li, C Yu, B Cheng, MB Feng, cl Hui, YZ CHINESE ACAD SCI SHANGHAI INST ORGAN CHEMSTATE KEY LAB BIOORGAN & NAT PROD CHEMSHANGHAI 200032PEOPLES R CHINA

Diosgenyl alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1) and Diosgenyl alpha-L-rhamnopyranosyl-(1-->2)-beta-D-xylopyranoside (2) were shown to be fascinating ''facial amphiphi... 详细信息

关键词： DYNAMICS CALCULATIONS MOLECULAR-DYNAMICS NMR GLYCOSIDES