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Stability and transferability assessment of the cotton fiber strength QTL qFS-c7-1 on chromosome A07

The crop Journal 2021年第2期9卷 380-386页

作者： David D.Fang Linghe Zeng Gregory N.Thyssen christopher D.Delhom Efrem Bechere don c.jones Ping Li cotton Fiber Bioscience Research Unit USDA-ARS-SRRCNew OrleansLA 70124USA crop Genetics Research Unit USDA-ARSStonevilleMS 38776USA cotton chemistry&Utilization Unit USDA-ARS-SRRCNew OrleansLA 70124USA cotton Structure and Quality Research Unit USDA-ARS-SRRCNew OrleansLA 70124USA cotton Incorporated CaryNC 27513USA

Previously we identified a major cotton fiber strength QTL(qFS-c7-1)on chromosome A07 using a multiparent advanced generation intercross(MAGIc)*** assess the stability and transferability of this QTL and its utility in cotton breeding,we made ten new *** populations were developed from crosses between MAGIc recombinant inbred lines,or between cotton cultivars that are different from the MAGIc parents.A total of 2801 F_(2) plants were grown and their fiber quality traits were *** also selected a subset of F_(3) seeds from two populations,and grew F_(3) progeny plots to further evaluate the stability of this *** results showed that the peak of qFS-c7-1 is at 70–72 Mb *** QTL had a major effect on fiber strength explaining 21.9%phenotypic *** effect on other fiber quality attributes such as micronaire,short fiber content,length and uniformity varied between populations,and no effect on fiber elongation was *** QTL effects were stable in the populations analyzed,and in different generations of the same *** SSR and SNP markers near and within the QTL peak reported herein will assist selecting superior fiber quality traits in breeding,with a recommendation that the parental cotton lines should be analyzed using the seven DNA markers within the QTL peak before fully implementing marker assisted selection in a cotton breeding program.

关键词： cotton Fiber quality Fiber strength MAGIc population qFS-c7-1

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Process development for the direct solvent extraction of nickel and cobalt from nitrate solution:aluminum,cobalt,and nickel separation using cyanex 272

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International Journal of Minerals,Metallurgy and Materials 2017年第1期24卷 37-46页

作者： Zela T.Ichlas don c.lbana Leaching and Separation Technologies Group Department of Mining Engineering and Metallurgical EngineeringWA School of MinesCurtin UniversityKalgoorlieWA 6430Australia

A direct solvent extraction（DSX） process for purifying nickel and cobalt from the nitric acid leach solution of nickel laterite ores was conceived and experimentally probed. The proposed process consists of two solvent extraction（SX） steps but with only one extractant - bis（2,4,4-trimethylpentyl）phosphinic acid（cyanex？ 272） - used in both steps. The first extraction step involved the removal of aluminum and zinc, whereas the second extraction step involved the separation of cobalt along with manganese from nickel. The experimental results showed essentially quantitative removal of aluminum（〉97%） and zinc（〉99%） in a single extraction stage using 20vol% cyanex 272 at pH 2.1. Some cobalt（32%） and manganese（55%） were co-extracted but were easily scrubbed out completely from the loaded organic phase using dilute sulfuric acid at pH ≤ 1.38. cobalt and manganese in the first extraction raffinate were extracted completely in four extraction stages at staggered pH values of 4.0, 4.4, 4.5, and 4.0 in the first, second, third, and fourth stages, respectively, using also 20vol% cyanex 272. A small amount of nickel（up to 6.6%） was co-extracted but was easily scrubbed out completely with dilute sulfuric acid at pH 2.0. A flow diagram showing the input and output conditions and the metals separated under the deduced optimum conditions is presented.

关键词： solvent extraction aluminum cobalt nickel nickel laterite ores

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Pandemic influenza: A global challenge for social marketing marketing

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Health 2012年第10期4卷 955-962页

作者： Sandra c. jones don Iverson centre for Health Initiatives University of Wollongong Wollongong Australia

Recent years have seen increased attention and concern regarding the potential for pandemic influenza, following large-scale outbreaks of swine flu and bird flu. Governments and health agencies have time to develop social marketing strategies and specific messages that have the potential to minimize fear, refute or inoculate against misinformation that the public may encounter, and enhance the likelihood of the public taking the recommended preventive and remedial actions should these become necessary. This paper presents an overview of how social marketing can be used to tackle the global challenge of pandemic influenza. The potential pandemic influenza poses a major challenge for social marketers (along with governments, health services, and businesses). There are a number of critical factors about a potential pandemic influenza that make it fundamentally different to the majority of issues to which social marketing has previously been applied. The underlying principles of social marketing are equally applicable to a global infectious disease outbreak (such as pandemic influenza). Even if the current strains do not become pandemic, social marketers should use this impetus to develop the skills and resources to address future communicable disease outbreaks. This paper applies the concepts of social marketing to a unique health issue which has the potential to become one of the largest global public health crises in history, but which can be tackled with effective global social marketing.

关键词： Pandemic Influenza Global Social Marketing communication Planning

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Hg and As Minerals in Fluid Inclusions from the Williams Mine, Hemlo, and Their Genetic Implications

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chinese Journal Of Geochemistry 2002年第1期21卷 1-18页

作者：卢焕章 JAYANTA.GUHA don.c.HARRIS Sciences de la Terre Universite du Quebec a chicoutimi chicoutimi Quebec Canada G7H 2B 1 Geological Survey of canada 601 Booth Street Ottawa Ont. Canada K1A 0E8

The Hemlo mineralization is enigmatic compared to general Archean lode gold deposits based on the fact that it is characterized by an exotic mineralogy containing elements such as As, Hg, Sb, Ba, V and Mo. The genetic concepts range from syngenetic to epigenetic types of mineralization. This reconnaissance study was designed to examine the relationship of Hg-As minerals with respect to fluid inclusions in the Williams mine (formerly known as the Page Williams mine) covering the A and c ore zones.

关键词：流体包裹体含汞矿物含砷矿物矿化作用金矿床

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The cellular microenvironment and cytoskeletal actin dynamics in liver fibrogenesis

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BIOcELL 2022年第9期46卷 2003-2007页

作者： NOUR HIJAZI don c.ROcKEY ZENGDUN SHI Medical University of South carolina Charleston29425USA

Hepatic stellate cells(HScs)are the primary effector cells in liver *** the normal liver,HScs serve as the primary vitamin A storage cells in the body and retain a“quiescent”***,after liver injury,they transdifferentiate to an“activated”myofibroblast-like phenotype,which is associated with dramatic upregulation of smooth muscle specific actin and extracellular matrix *** result is a fibrotic,stiff,and dysfunctional ***,understanding the molecular mechanisms that govern HSc function is essential for the development of anti-fibrotic *** actin cytoskeleton has emerged as a key component of the fibrogenic response in wound *** data indicate that the cytoskeleton receives signals from the cellular microenvironment and translates them to cellular function—in particular,increased type I collagen *** in nature,the actin cytoskeleton continuously polymerizes and depolymerizes in response to changes in the cellular *** this viewpoint,we discuss the recent developments underlying cytoskeletal actin dynamics in liver fibrosis,including how the cellular microenvironment affects HSc function and the molecular mechanisms that regulate the actininduced increase in collagen expression typical of activated HScs.

关键词： Extracellular matrix Actin dynamics Transcriptional regulation Signaling

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One step at a time:new insights into double-stranded ribonucleic acid virus assembly

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Signal Transduction and Targeted Therapy 2024年第10期9卷 4160-4161页

作者： Virgile Rat Alexander Borodavka don c.Lamb Department of chemistry LMU MünchenMünchen GermanyButenandtstrasse 5-1381377MunichGermany Department of chemical Engineering and Biotechnology University of CambridgePhilippa Fawcett DriveCB30ASCambridgeUK

In a recent paper published in cell,Xia et al.1 carried out 3D reconstructions of Blue Tongue Virus(BTV)particles and their assembly intermediates using a combination of cellular cryo-electron tomography(cryo-ET)and single-particle cryo-electron microscopy(cryo-EM).They were able to identify 11 structures,allowing them to refine our understanding of how double-stranded ribonucleic acid(dsRNA)viruses replicate in cells.

关键词： double assembly insight

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Predisposing factors’effects on mortality of oak (Quercus) and hickory (carya) species in mature forests undergoing mesophication in Appalachian Ohio

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Forest Ecosystems 2021年第1期8卷 81-94页

作者： don c.Radcliffe David M.Hix Stephen N.Matthews School of Environment and Natural Resources The Ohio State University2021 Coffey RoadColumbus OH 43210USA School of Environmental and Forest Sciences University of WashingtonBox 352100Seattle WA 98195-2100USA

Background:Mature oak(Quercus spp.)and hickory(carya spp.)trees are gradually being replaced by more shadetolerant tree species across the eastern U.S.,likely due to fire suppression and increased *** and hickories are highly valuable to wildlife;therefore,studying their mortality patterns can provide information on the longevity of habitat quality for many animal *** mortality has most often been studied following large oak decline events,but background mortality rates in forests with aging oak and hickory canopies warrant equal attention,especially in the context of widespread oak and hickory regeneration ***:We studied background mortality rates of five oak and one hickory species over a 23–25 year time period(1993–1995 to 2018),using 821/20th hectare permanent plots on the Marietta Unit of the Wayne National Forest in southeastern *** calculated mortality rates based on remeasurement of individual trees for white oak(Quercus alba),chestnut oak(Quercus montana),northern red oak(Quercus rubra),black oak(Quercus velutina),scarlet oak(Quercus coccinea),and pignut hickory(carya glabra).For each of these species other than scarlet oak,we also modeled the relationships of mortality probability with a priori topographic,soil,stand structural,and individual tree covariates,using a mixed-effects logistic regression ***:The species with the highest mortality rate was scarlet oak(61.3%),followed by northern red oak(41.4%),black oak(26.7%),pignut hickory(23.9%),white oak(23.4%),and chestnut oak(19.1%).In our models,northern red oak mortality was associated with more mesic slope positions,shallower solums,more acidic soils,and older stand *** hickory and chestnut oak mortality rates were associated with higher basal areas on the plot,while white oak mortality showed the opposite ***:Our data suggest that red oak subgenus trees in mature forests of our area will become increasingly uncommon relative t

关键词： Mortality Quercus carya Mesophication Wildlife habitat

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Liver alveolar echinococcosis in china: clinical aspect with relative basic research

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World Journal of Gastroenterology 2005年第30期11卷 4611-4617页

作者： ci-Peng Jiang McManus don Malcolm jones Hydatidosis Research Laboratory of Basic Medical School Lanzhou University Lanzhou 730000 Gansu Province China Post Office Royal Brisbane Hospital Q 4029 Australia

This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and *** review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TcM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.

关键词： Echinococcosis Alveolar echinococcosis Liver clinical aspect Basic research china

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Approximate equivalence in von Neumann algebras

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Science china Mathematics 2005年第2期48卷 239-247页

作者： DING Huiru don Hadwin Department of Mathematics University of New HampshireDurhamNH03824USA Department of MathematicsUniversity of New HampshireDurhamNH03824USA

One formulation of D. Voiculescu's theorem on approximate unitary equivalence is that two unital representations π and ρ of a separable c*-algebra are approximately unitarily equivalent if and only if rank οπ = rank ορ. We study the analog when the ranges of π and ρ are contained in a von Neumann algebra R, the unitaries inducing the approximate equivalence must come from R, and 'rank' is replaced with 'R -rank' (defined as the Murray-von Neumann equivalence of the range projection).

关键词： approximate equivalence, R-rank.

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What can computational modeling offer for studying the ca^(2+) dysregulation in Alzheimer's disease:current research and future directions

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Neural Regeneration Research 2018年第7期13卷 1156-1158页

作者： Jingyi Liang don Kulasiri centre for Advanced computational Solutions(c-fAcS) Lincoln University

ca^2＋ dysregulation is an early event observed in Alzheimer＇s disease（AD） patients preceding the presence of its clinical *** of neuronalca^2＋ will cause synaptic loss and neuronal death,eventually leading to memory impairments and cognitive *** targetingca^2＋ signaling pathways are potential therapeutic strategies against *** complicated interactions make it challenging and expensive to study the underlying mechanisms as to how ca^2＋ signaling contributes to the pathogenesis of *** modeling offers new opportunities to study the signaling pathway and test proposed *** this mini-review,we present some computational approaches that have been used to study ca^2＋ dysregulation of AD by simulating ca^2＋signaling at various *** also pointed out the future directions that computational modeling can be done in studying the ca^2＋ dysregulation in AD.

关键词： Alzheimer's disease amyloid-beta ca^2+ hypothesis ca^2+ dysregulation computational modeling computational neuroscience

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