One step at a time:new insights into double-stranded ribonucleic acid virus assembly

作     者：Virgile Rat Alexander Borodavka Don C.Lamb 

作者机构：Department of ChemistryLMU MünchenMünchen GermanyButenandtstrasse 5-1381377MunichGermany Department of Chemical Engineering and BiotechnologyUniversity of CambridgePhilippa Fawcett DriveCB30ASCambridgeUK 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2024年第9卷第10期

页      面：4160-4161页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

基　　金：Open Access funding enabled and organized by Projekt DEAL 

主　　题：double assembly insight 

摘      要：In a recent paper published in Cell,Xia et al.1 carried out 3D reconstructions of Blue Tongue Virus(BTV)particles and their assembly intermediates using a combination of cellular cryo-electron tomography(Cryo-ET)and single-particle cryo-electron microscopy(Cryo-EM).They were able to identify 11 structures,allowing them to refine our understanding of how double-stranded ribonucleic acid(dsRNA)viruses replicate in cells.