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Getting ready for the next inforuses

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hLife 2024年第2期2卷 94-95页

作者： Andrécosta lobato Institute of Economics Federal University of Rio de JaneiroRio de JaneiroBrazil

With the end of Corona Virus Disease 2019(COVID-19)as a global health emergency in May 2023[1],experts can now meet face-to-face to discuss what people were saying and doing behind the keyboards during our first global‘paninfodemic’,the term used to describe the abundance of information[2],helpful or dangerous,during a disease outbreak.

关键词： global info

打造友善合作空间:中国和巴西基于多学科领域的全球健康合作

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Science Bulletin 2023年第20期68卷 2293-2294页

作者： Andre costa lobato Carlos Medicis Morel George Fu Gao Institute of Economics Federal University of Rio de JaneiroRio de Janeiro 22290-902Brazil Center for Technology Development in Health Oswaldo Cruz FoundationRio de Janeiro 21040-361Brazil Federal University of Rio de Janeiro Rio de Janeiro 22290-902Brazil CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China University of the Chinese Academy of Sciences Beijing 100049China

Brazilian president Luiz Inacio Lula da Silva’s visit to China in April 2023 was an opportunity to elevate health cooperation between the two countries to scientific and technological cooperation standards,exemplified by the China-Brazil Earth Resources Satellite(CBERS).The satellite programme can be traced back to the Basic Agreement on Scientific and Technological Cooperation signed by the two nations in 1982(https://***/ccivil03/decreto/1990-1994/***).This framework serves as a reference for health cooperation between Chinese science and health institutions and the Oswaldo Cruz Foundation(Fiocruz),the Brazilian Minister of Health’s core industrial and research facility.

关键词： cooperation Basic Brazil

International cooperation in science,technology,and health,challenges and perspective

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hLife 2024年第5期2卷 207-210页

作者： Andrécosta lobato Carlos Medicis Morel Yi Shen Institute of Economics Federal University of Rio de JaneiroRio de JaneiroBrazil Center for Technology Development in Health Oswaldo Cruz FoundationRio de JaneiroBrazil Federal University of Rio de Janeiro Rio de JaneiroBrazil International Research Institution of Global Cyberspace Governance Fudan UniversityShanghaiChina

International cooperation in science and technology is a major challenge for developing countries such as Brazil and *** the“safari research,”in which poor countries enter with the disease and the rich countries with technology,to new frameworks such as the BRICS,professors Carlos Medicis Morel,from Brazil’s Oswaldo Cruz Foundation,and Yi Shen,from China’s Fudan University,have a dialogue mediated by Andrécosta lobato,on the challenges and perspectives for cooperation in the global *** the bottom-up process usually leads to fruitful cooperation,the top–down political support is relevant to provide a proper environment for *** dialogue explored the differences in scientific structures between Brazil and China,language barriers,and the need for effective *** discussed the evolution of BRICS beyond economic cooperation,emphasizing its role in global governance,science,technology,and *** professors addressed the benefits of international collaboration,including knowledge exchange,exposure to different cultures,and solving common problems.

关键词： cooperation Brazil technology

Support Vector Machine and Artificial Neural Networks for Hydrological Cycles Classifications of a Water Reservoir in the Amazon

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通讯和计算机（中英文版） 2014年第2期11卷 111-117页

作者： Jean Carlos Arouche Freire Tarcisio da costa lobato Jefferson Magalhaes de Morais Terezinha Ferreira de Oliveira Rachel Anne Hauser-davis Augusto Cesar Fonseca Saraiva Faculty of Computing Federal University of Pard City Belem 66. 075-110 Brazil Faculty of Mathematics and Statistics Federal University of Para Belem 66. 075-110 Brazil Departament of Chemmistry Pontifical Catholic University of Rio de Janeiro Rio de Janeiro 22451-900 Brazil Technology Center Eletrobras-Eletronorte Belem 66115-000 Brazil

Serological surveillance for SARS-CoV-2 antibodies among students,faculty and staff within a large university system during the pandemic

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World Journal of Virology 2025年第1期14卷 99-107页

作者： Marcos G Pinheiro Gabriela G O Alves Maria Eduarda R Conde Sofia L costa Regina C S Sant’Anna Isa M F Antunes Mônica C Carneiro Fabio S Ronzei Julia C Scaffo Felipe R Pinheiro Lialyz S Andre Helvecio C Povoa Valéria T Baltar Fabíola Giordani Eduarda S Hemerly Gisele C Alexandre Karla C de Paula Márcio Watanabe Antonio Claudio L da Nóbrega Jackeline Christiane P lobato Fabio Aguiar-Alves Laboratory of Molecular Epidemiology and Biotechnology Rodolpho Albino University LaboratoryFluminense Federal UniversityNiterói 24241000Rio de JaneiroBrazil Estácio de SáUniversity Nova Friburgo 28611135Rio de JaneiroBrazil Pathology Program Medicine schoolFluminense Federal UniversityNiterói 24070090Rio de JaneiroBrazil Department of Pharmaceutical Sciences Lloyd L.Gregory School of PharmacyPalm Beach Atlantic UniversityWest Palm BeachFL 33401United States Health Institute of Nova Friburgo Fluminense Federal UniversityNova Friburgo 28613001Rio de JaneiroBrazil Department of Epidemiology and Biostatistics Institute of Collective Health(ISC)Fluminense Federal UniversityNiterói 24033900Rio de JaneiroBrazil Institute of Physical Education Fluminense Federal UniversityNiterói 24020005Rio de JaneiroBrazil Department of Statistics Fluminense Federal UniversityNiterói 24210200Rio de JaneiroBrazil Department of Physiology and Pharmacology Fluminense Federal UniversityNiterói 24210130Rio de JaneiroBrazil

BACKGROUND At the end of December 2019,the world faced severe acute respiratory syndrome-coronavirus 2(SARS-CoV-2),which led to the outbreak of coronavirus disease 2019(COVID-19),associated with respiratory *** virus has shown significant challenges,especially for senior citizens,patients with other underlying illnesses,or those with a sedentary *** tests conducted early on have helped identify how the virus is transmitted and how to curb its *** study hypothesis was that the rapid serological test for SARS-CoV-2 antibodies could indicate the immunoreactive profile during the COVID-19 pandemic in a university *** To conduct active surveillance for serological expression of anti-SARS-CoV-2 antibodies in individuals within a university setting during the COVID-19 *** This sectional study by convenience sampling was conducted in a large university in Niteroi-RJ,Brazil,from March 2021 to July *** study population consisted of students,faculty,and administrative staff employed by the university.A total of 3433 faculty members,60703 students,and 3812 administrative staff were invited to *** were gathered through rapid serological tests to detect immunoglobulin(Ig)M and IgG against ***χ²or Fisher's exact test was used to conduct statistical analysis.A 0.20 significance level was adopted for variable selection in a multiple logistic regression model to evaluate *** A total of 1648 individuals were enrolled in the *** proportion of COVID-19 positivity was 164/1648(9.8%).The adjusted logistic model indicate a positive association between the expression of IgM or IgG and age[odds ratio(OR)=1.16,95%CI:1.02-1.31](P<0.0024),individuals who had been in contact with a COVID-19-positive case(OR=3.49,95%CI:2.34-5.37)(P<0.001),those who had received the COVID-19 vaccine(OR=2.33,95%CI:1.61-3.35)(P<0.001)and social isolation(OR=0.59,95%CI:0.41-0.84)(P<0.004).The likelihood of sho

关键词： Serological surveillance SARS-CoV-2 antibodies COVID-19 Serological rapid test Risk factors for COVID-19

Selection of Strains Producing Lipase with Transesterification Activity and Its Characterization

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Journal of Chemistry and Chemical Engineering 2016年第2期10卷 68-76页

作者： Gabriel Luls Castighoni Jorge Alberto Vieira costa Giovana da Silva Padilha Ranulfo Monte-Alegre Department of Food Engineering School of Agronomy Federal University of Goi6s Rodovia Goifnia/Nova Veneza Km O Goiania GO 74690-900 Brazil Department of Chemical Engineering Federal University of Rio Grande Rua Engenheiro Alfredo Huch Rio Grande 96201-900 Brazil Department of Food Engineering University of the State of Campinas Rua Monteiro Lobato 80 Campinas 13083-862 Brazil

The interest for lipase production is due to the ability of this enzyme to catalyze some reactions, such as the transesterification. Although industrial biodiesel is produced chemically, there are several problems associated with this technology that can be prevented through the use of lipases. The present work aimed to select microorganisms with potential for production of lipase with transesterification activity. The lipase from Burkholderia cepacia was the one with the most promising results for this type of reaction, showing results of hydrolytic activity at 37 ℃and pH 8.0. The pH and volume of crude enzyme extract that showed favorable for synthesis ofbiodiesel is at about pH 6.0 and 3.75 mL, respectively, which represents approximately 42% of water in the system, ensuring the conversion of nearly 60% to biodiesel.

关键词： Biodiesel Burkholderia cepacia characterization lipase transesterification.

Resolutive Results with Oral Corticosteroids for Patients with COVID-19 in Pulmonary Inflammatory Phase. Successful Outpatient Experience during the Collapse of Belem Do Para Health System—Brazil

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Health 2021年第8期13卷 830-838页

作者： Roberto S. Zeballos Luciana N. L. Cruz Vânia C. R. Brilhante Adriana V. Lima Carlliane L. L. P. Martins Karla N. A. Lima Michele C. G. L. Leão Belinete L. Cruz Alessandra B. Dysarz Paulo C. B. lobato Erika S. Almeida Rute A. P. costa Klevison C. Araújo Augusto C. C. Almeida Leônidas B. D. Junior Kathia O. Harada Rita H. V. S. Araújo Elaine X. Prestes Ivete M. S. Souza Avany M. P. Pereira Antônio B. M. A. Rocha Iracema A. Estevão Fagnei I. C. Carvalho Paulo M. P. Melo Clinical Care Sao Paulo Brazil Instituto de Ciencias da Saude Faculdade de Medicina Universidade Federal do Para Belem Brazil Fundacao Publica Estadual Hospital de Clinicas Gaspar Vianna Belem Brazil Hospital da Policia Militar do Para Belem Brazil Imunoclinic Belem Brazil Universidade Estadual do Para Fundacao Santa Casa de Misericordia do Para Belem Brazil Clinica Barros Cirurgia Plastica Belem Brazil Secretaria de Estado de Saude Publica Castanhal Brazil Centro de Tratamento Oncologico Belem Brazil Sociedade Brasileira de Valorizaç ã o das Sociedades Medicas—SOBEMED S&#227 o Paulo Brazil Clinica de Nutrologia Sao Luiz Brazil Hospital Nipo Brasileiro de Olhos Belem Brazil Centro de Ciencias Biologicas e da Saude Universidade do Estado do Para Belem Brazil Hospital Regional do Baixo Amazonas Santarem Brazil Clinica Vallinoto Secretaria de Saude de Barcarena Barcarena Brazil Estrategia Saude da Familia Secretaria Municipal de Saude de Ananindeua Centro Universitario do Estado do Para Belem Brazil A. M. P. Endocrinologia Belem Brazil Instituto Avertano Rocha Belem Brazil Departamento de Neurocirurgia Hospital Militar de Area De Sao Paulo Sao Paulo Brazil

In the face of new diseases, medicine needs to reinvent itself in order to contain and control epidemics, such as the one we have recently faced, COVID-19, a disease with a wide spectrum of clinical severity. A new moment has been established, since the application of well-known, effective and safe medications for other diseases, has shown high success rates in the treatment of COVID-19. Thereunto, studies with early intervention are needed, which can change the unfavorable outcome of patients. In this article, we report the successful experience using an oral strategy during the collapse of Belem (Para, Brazil) Health System. Two hundred and ten patients were diagnosed with respiratory failure due to COVID-19, with no option of hospital treatment due to lack of beds and resources. These patients were then started on therapeutic regimen consisting of 40 mg prednisolone, 40 mg enoxaparin and macrolides (500 mg clarithromycin, 500 mg axetylcefuroxime) associated and followed in outpatient facilities. Two hundred and eight patients had an excellent therapeutic response and there were only two fatalities. These results push research boundaries, valuing outpatient treatment with early use of prednisolone in the initial pulmonary phase, preventing severe COVID-19 pneumonitis. Adoption of the proposed treatment intends to reduce the need for hospitalization, as well as lethality, with social robust benefits and incalculable economic savings since involves the use of accessible, safe and not expensive medications.

关键词： COVID-19 Corticosteroids Pulmonary Inflammatory Phase Collapse Brazil