Analysis of 472,688 Severe Cases of COVID-19 in Brazil Showed Lower Mortality in Those Vaccinated against Influenza

作     者：Daniele Melo Sardinha Diana da Costa Lobato Ana Lú cia da Silva Ferreira Karla Valé ria Batista Lima Ricardo José de Paula Souza e Guimarã es Luana Nepomuceno Gondim Costa Lima Daniele Melo Sardinha;Diana da Costa Lobato;Ana Lúcia da Silva Ferreira;Karla Valéria Batista Lima;Ricardo Joséde Paula Souza e Guimarães;Luana Nepomuceno Gondim Costa Lima

作者机构：Post-graduate Program in Epidemiology and Health Surveillance of the Instituto Evandro Chagas (PPGEVS/IEC) Ananindeua Pará  Brazil State Coordinator of the Reference Center for Special Immunobiologicals from the Pará State Public Health Department (CRIE/SESPA) Belé m Pará  Brazil Post-Graduation Program in Parasite Biology in the Amazon University of state of Pará  Instituto Evandro Chagas (PPGBPA/UEPA/IEC) Belé m Pará  Brazil 

出 版 物：《World Journal of Vaccines》 (疫苗（英文）)

年 卷 期：2021年第11卷第3期

页      面：28-32页

学科分类：0401[教育学-教育学] 04[教育学] 

主　　题：COVID-19 Pandemic Brazil Influenza Vaccine 

摘      要：Objective: To analyze the severe cases of COVID-19 in Brazil in 2020 and compare those vaccinated and unvaccinated against influenza in invasive ventilation, admission in Intensive Care Unit (ICU) and deaths. Method: Cross-sectional study with public data from the OpenDataSUS platform, regarding confirmed severe cases for COVID-19 in Brazil in the year 2020. Data were analyzed by SPSS, from the chi-square test of independence and binary logistic regression. Results: The population was 472,688 cases and 177,640 deaths, with a lethality of 37.58% in severe cases. The test of independence was highly significant in vaccinated survivors (0.0001), and regression showed an almost twofold odds ratio for invasive ventilation, ICU admission, and death in unvaccinated cases. Conclusion: We recommend mass influenza vaccination as an adjuvant in combating the COVID-19 pandemic in Brazil.