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INHERITANCE OF PRECIPITATED V_4C_3 IN MARTENSITIC TRANSFORMATION

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Acta Metallurgica Sinica(English Letters) 1992年第2期5卷 82-88页

作者： XIE Changsheng sun Peizhen ZHAO Jiansheng sun desheng Huazhong University of Science and Technology,Wuhan,China Huazhong Univ of Science and Technology Wuhan China

The inheritance phenomenon of precipitated V_4C_3 in martensitic transformation has been in- vestigated by means of electron diffraction and matrix analysis.A crystallographic orientation relation among austenite,martensite and V_4C_3 carbide was found to be. (010)_A∥( 10)_M∥(010)_(v_4c_3), [10 ]∥[11 ]_M [10 ]_(v_4c_3) The V_4C_3 first precipitated in austenite,and then was inherited to *** cer- tain orientation relation was kept between V_4C_3 and martensite,the interfacial structural ana- lysis pointed out that the biphase interfacial energy is higher than that determined by Baker-Nutting relation,thus it is *** the V_4C_3 precipitated along the crystalline defects in austenite,they could be inherited to martensite.

关键词： V_4C_3 transformation inheritance orientation

Shikonin alleviates collagen-induced arthritis mice by inhibiting M1 macrophage polarization

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Journal of Traditional Chinese Medicine 2022年第6期42卷 932-939页

作者： HE Lianhua LUAN Huijie QIN Qingxia HE Juan CHEN Jian HU Yiping CAI Yueming sun desheng SHI Yu WANG Qingwen Department of Rheumatism and Immunology Peking University Shenzhen HospitalShenzhen 518036China Shenzhen China Resources Sanjiu Pharmaceutical Trading Co. Ltd.Shenzhen 518029China The Key Laboratory of Inflammatory and Immunology Diseases Shenzhen 518036China Department of ultrasound Peking University Shenzhen HospitalShenzhen 518036China

OBJECTIVE: To investigate the effects of shikonin(SKN) on M1 and M2 polarization of macrophages both in vitro and in vivo. METHODS: Collagen-induced arthritis(CIA) in male DBA/1 mice were treated with a dose of 4 mg/kg/day of SKN for 23 d(n = 6/group). The histopathology of inflamed joints in CIA mice was evaluated to test the antiarthritic effect of SKN. M1/M2 polarization of macrophages induced by lipopolysaccharide(LPS) and interferon(IFN)-γ or interleukin(IL)-4 and IL-13, were used to assess the effect of SKN(0.05, 0.1, and 0.2 μM). The effect of SKN on the protein expression of nitric oxide synthase, arginase, CD68, and CD206 was evaluated using western blot analysis. RESULTS: The results of this study revealed that SKN delayed the arthritis feet symptom score, reduced the incidence rate of arthritis, and relieved the inflammation of joints in CIA mice. SKN inhibited M1 macrophage polarization but did not affect M2 macrophage polarization in the joints of CIA mice. Moreover, SKN inhibited M1 polarization induced by LPS and IFN-γ, but did not affect M2 polarization induced by IL-4 and IL-13. CONCLUSION: These findings suggest that SKN alleviated CIA through inhibiting M1 macrophage polarization and has great potential as a new drug for RA treatment.

关键词： Shikonin arthritis rheumatoid macrophages M1 polarization

Blocking CCL20 can attenuate the impact of dendritic cells on COPD

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Blocking CCL20 can attenuate the impact of dendritic cells o...

中华医学会呼吸病学年会——2013（第十四次全国呼吸病...

作者： desheng sun Yao Ouyang Yanhui Gu Department of Respiratory Medicine Affiliated Hospital of Zunyi Medical College

Objectives To investigate the expressions of dendritic cells(DCs) and its chemokine receptors in this rat model of COPD and the therapeutic effect of anti-CCL20 therapy on it. Methods 18 Wistar rats were randomized into a control group,a COPD model group and a CCL20 monoclonal antibody treated *** the latter two groups,COPD was induced by established cigarette smoke inhalation about four weeks and intratracheal 200ug/200ul of LPS solution twice ***20 monoclonal antibody was

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高管团队与企业社会责任:高阶理论的视角

科学学与科学技术管理 2009年第4期30卷 188-193页

作者：孙德升南开大学商学院天津300071

整合了相关的文献,从高阶理论的视角提出了一个高管团队特征与企业社会责任关系的分析框架,认为高层管理者的背景特征能在一定程度上预测企业的社会责任行为,并对主要自变量与企业社会责任之间可能存在的关系进行了考察。

关键词：企业社会责任高阶理论高管团队特征

Application of Wireless Transmission Technology in Weapon setting

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Application of Wireless Transmission Technology in Weapon se...

Advances in microbubble-assisted ultrasound-guided gene therapy:Mechanisms and applications

第37届中国控制会议

作者： Bo Zhao Jing Wang desheng sun Hua Zhou Beijing Aerospace Automatic Control Institute National Key Laboratory of Science and Technology on Aerospace Intelligence Control

It takes time to insert and pull out the plug in the wired way to settle the key parameters to a weapon before *** order to shorten the setting time and communicate with multiple shells or missiles at one time, the wireless setting system had been designed, which consisted of the wireless communication system and the wireless power system. The wireless communication system in which chip CC2530 was used had been designed on the basis of Simplici TI. The wireless power system includes the transmitter module which uses chip bq500210 and the receiver module which uses chip bq51013 A. The comprising and function of the system, the design of the hardware and software had been introduced. The experiments showed that the good capability of the wireless setting system could shorten the setting time compared to the wired setting ways.

关键词： Wireless Setting Wireless communication Wireless Power

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Science China Materials 2024年第9期67卷 2749-2766页

作者： Zhen Tie Shuhao Zhang Yunfeng Qu Mengxuan Wang Renfa Liu desheng sun Zhifei Dai Department of Biomedical Engineering College of Future TechnologyNational Biomedical Imaging CenterState Key Laboratory of Vascular Homeostasis and RemodelingPeking UniversityBeijing 100871China Department of Ultrasonic Imaging Peking University Shenzhen HospitalShenzhen 518035China

Gene therapy,as one of the popular therapies nowadays,has been applied with great success in various ***,there are also concerns about the safety,therapeutic efficacy,and applicability of gene ***crobubble-assisted ultrasound-guided gene therapy offers the following incomparable advantages over conventional meth***,this strategy enables the therapeutic nucleic acids to effectively cross the barriers like cell membrane,blood-brain barrier,and blood-retinal barrier that exist in the body and reach regions that cannot be accessed by conventional methods,which extends the scope of applications of gene ***,it is possible to restrict the zone of gene transfection to the lesion area by controlling the irradiation coverage of ultrasound,hence effectively controlling the risk of ***,with the support of various imaging techniques like ultrasound imaging and magnetic resonance imaging,the procedure of gene therapy can be under image guidance,which will dramatically improve the safety of gene *** review will highlight on the advances in ultrasound-enhanced gene delivery strategy,attention to the relevant mechanisms of the strategy,the derived technologies and the related cutting-edge ***,we will also have a discussion on the limitations and future prospects associated with this gene delivery strategy.

关键词： gene therapy microbubble ultrasound cavitation image-guided gene therapy

变温带地下仓埋深对长期储粮过程粮堆温度影响的模拟研究

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中国粮油学报 2015年第5期30卷 78-83页

作者：陈雁孙德胜河南工业大学土木建筑学院郑州450001 河南职业技术学院郑州450000

为研究我国不同区域采用地下仓储粮的温度适宜性,基于有限容积法和交替方向隐式迭代法对变温带地下仓系统的守恒方程进行了离散求解。考虑粮食呼吸热、环境气温变化和地下仓埋深等因素的影响,经过机械通风和人工制冷2种不同降温方式后,... 详细信息

为研究我国不同区域采用地下仓储粮的温度适宜性,基于有限容积法和交替方向隐式迭代法对变温带地下仓系统的守恒方程进行了离散求解。考虑粮食呼吸热、环境气温变化和地下仓埋深等因素的影响,经过机械通风和人工制冷2种不同降温方式后,得到了5个代表城市长期储藏过程中地下仓粮堆内的温度分布及变化。结果表明:上层粮堆温度受气温影响,呈现滞后气温的正弦规律性,下部取决于恒温带温度水平,整体呈现与地上储仓类似的"热皮冷心"趋势,但在2种降温方式下"热皮"区温度较平房仓分别降低了约4℃和9℃。冬季粮食通风后储藏,即使埋深较浅(1 m),华中和华北仍可实现低温储粮的目标。

关键词：地下仓低温储粮粮堆温度埋深

空气源热泵-太阳能组合系统在寒冷地区运行特性的模拟研究

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暖通空调 2011年第7期41卷 123-127页

作者：陈雁孙德胜河南工业大学河南职业技术学院

对郑州某办公楼的空气源热泵供暖系统进行了供暖性能实验,分析了室外气温和供暖负荷率对机组运行效果的影响,结果表明,寒冷地区冬季采用空气源热泵进行供暖具有技术可行性但并不经济。基于实验数据,对空气源热泵-太阳能组合系统进行了... 详细信息

对郑州某办公楼的空气源热泵供暖系统进行了供暖性能实验,分析了室外气温和供暖负荷率对机组运行效果的影响,结果表明,寒冷地区冬季采用空气源热泵进行供暖具有技术可行性但并不经济。基于实验数据,对空气源热泵-太阳能组合系统进行了模拟研究,分析了不同供暖面积下,冷凝温度、蒸发温度、集热器面积及供水温度等对热泵供暖运行性能的影响,提出较为合理的匹配及运行方式。

关键词：空气源热泵太阳能供暖平板空气集热器

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中国制造业转型升级与新微笑曲线理论

科技进步与对策 2017年第15期34卷 49-54页

作者：孙德升刘峰陈志南开大学经济与社会发展研究院与中国科学技术发展战略研究院联合博士后工作站北京100038 天津社会科学院京津冀及城市群发展研究中心天津300191 中国科学技术发展战略研究院北京100038

鉴于中国制造业转型升级支持理论的不足,将科技水平变量引入传统微笑曲线模型,发现传统微笑曲线理论和倒微笑曲线理论仅描述了产业链附加值分布图的一部分,只有两者结合才能构成完整的微笑曲线理论,即新微笑曲线理论。此外,基于新微笑... 详细信息

鉴于中国制造业转型升级支持理论的不足,将科技水平变量引入传统微笑曲线模型,发现传统微笑曲线理论和倒微笑曲线理论仅描述了产业链附加值分布图的一部分,只有两者结合才能构成完整的微笑曲线理论,即新微笑曲线理论。此外,基于新微笑曲线理论,提出对中国制造业转型升级的3个重要启示:(1)无论选择哪一条转型升级路径,加大科技投入、进行科技创新及提升科技水平均是中国制造业实现转型升级的根本路径;(2)价值链高端和低端的划分实际上是一个动态变化的概念,只要加大生产制造环节的科技投入,积极进行科技创新,大幅提升其科技水平,在一定条件下,产业链生产制造环节也能处于价值链高端;(3)对于当前大多数中国制造企业而言,其转型升级路径是直接在生产制造环节进行转型升级而非沿着产业链向两端攀升。

关键词：中国制造业转型升级新微笑曲线理论