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双能CT评估转移性淋巴结和非转移性淋巴结碘摄取量和分布的差异

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国际医学放射学杂志 2018年第2期 247-247页

作者： R.Stefania R.davide F.Marco D.M.Paolo O.Daniela P.Lorenzo 王习 Department of Radiology European Institute of Oncology

摘要目的采用双能CT评估转移性淋巴结和非转移性淋巴结中碘摄取量,并分析碘的分布是否与淋巴结的病理结构有关。方法回顾分析37例病人共90个淋巴结(其中23

关键词：淋巴结转移性摄取量 CT

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灵动灯饰:空间的点睛之笔

现代装饰（家居） 2016年第12期 64-71页

作者： davide G.Aquini Kazuhiro Yamanaka Kristina Dam Marleen Kaplein LucidiPevere Jordi Lopez Aguilo Maria Novozhilova OWL paperlamps OOO My Design Vasileios Roumeliotis Moreno Ratti Satoshi Itasaka/h22O430 Marcel Wanders 彭佳 MEJD Studio Studio Drift Jordi Lopez Aguilo-kutarq design studio

夜幕降临，华灯初上，混浊的黑夜渐渐放出了光亮。望着远方忽明忽暗的点点星火，行走的旅人是否感受到了家的温暖……一盏小小的灯，虽然只是一种照明工具，却被寄予了亘古不变的情怀。不管是昏黄老旧的煤油灯，还是再普通不过的白炽灯... 详细信息

夜幕降临，华灯初上，混浊的黑夜渐渐放出了光亮。望着远方忽明忽暗的点点星火，行走的旅人是否感受到了家的温暖……一盏小小的灯，虽然只是一种照明工具，却被寄予了亘古不变的情怀。不管是昏黄老旧的煤油灯，还是再普通不过的白炽灯，都会让我们在黑暗中寻到温暖的家的气息，给予我们燃烧着的希望。

关键词：灯饰空间煤油灯白炽灯温暖

Same-day 2-L PEG-citrate-simethicone plus bisacodyl vs split 4-L PEG: Bowel cleansing for late-morning colonoscopy

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World Journal of Gastrointestinal Endoscopy 2013年第9期5卷 433-439页

作者： Annalisa de Leone Darina Tamayo Giancarla Fiori davide Ravizza Cristina Trovato Giuseppe De Roberto Linda Fazzini Marco Dal Fante Cristiano Crosta Division of Endoscopy European Institute of Oncology Gastroenterology and Endoscopy Department

AIM: To evaluate the efficacy, tolerability, acceptability and feasibility of bisacodyl plus low volume polyethyleneglycol-citrate-simeticone(2-L PEG-CS) taken the same day as compared with conventional split-dose 4-L PEG for late morning colonoscopy. METHODS: Randomised, observer-blind, parallel group, comparative trial carried out in 2 centres. Out patients of both sexes, aged between 18 and 85 years, undergoing colonoscopy for diagnostic investigation, colorectal cancer screening or follow-up were eligible. The PEG-CS group received 3 bisacodyl tablets(4 tablets for patients with constipation) at bedtime and 2-L PEG-CS in the morning starting 5 h before colonoscopy. The control group received a conventional 4-L PEG formulation given as split regimen; the morning dose was taken with the same schedule of the low volume preparation. The Ottawa Bowel Preparation Scale(OBPS) score was used as the main outcome ***: A total of 164 subjects were enrolled and 154 completed the study; 78 in the PEG-CS group and 76 in the split 4-L PEG group. The two groups were comparable at baseline. The OBPS score in the PEG-CS group(3.09 ± 2.40) and in the PEG group(2.39 ± 2.55) were equivalent(difference +0.70; 95%CI:-0.09-1.48). This was confirmed by the rate of successful bowel cleansing in the PEG-CS group(89.7%) and in the PEG group(92.1%)(difference-2.4%; 95%CI:-11.406.70). PEG-CS was superior in terms of mucosa visibility compared to PEG(85.7% vs 72.4%, P = 0.042). There were no significant differences in caecum intubation rate, time to reach the caecum and withdrawal time between the two groups. The adenoma detection rate was similar(PEG-CS 43.6% vs PEG 44.7%). No serious adverse events occurred. No difference was found in tolerability of the bowel preparations. Compliance was equal in both groups: more than 90% of subjects drunk the whole solution. Willingness to repeat the same bowel preparations was about 90% for both regimes. CONCLUSION: Same-day PEG-CS is feasib

关键词： Bowel preparation Polyethyleneglycol Simethicone Ottawa Bowel Preparation Scale Colonoscopy

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大都会及杜嘉班纳总部大楼意大利米兰

世界建筑导报 2018年第5期33卷 72-75页

作者： Luca Lazzerotti Micaela Bonomessi Silvia Calzetti Laura Cassani Gabriele Coi Marco Dragoni davide Fascione Suewoo Kim Magali Roig Liverato Michele Megna Elena Migliorati Gianni Mollo Andrea Palaia Salvatore Seggio 布鲁克.泰勒 Andrea Martiradonna Piuarch

大都会（Metrop01）项目是对米兰一座著名的地标建筑——可追溯到20世纪40年代的大都会影院进行的翻新。影院坐落于市中心的维亚尔皮亚韦（viale Piave）繁华地段，玛丽亚·卡拉斯（Maria Callas）曾在这里进行歌剧《诺玛》的录制。项... 详细信息

大都会（Metrop01）项目是对米兰一座著名的地标建筑——可追溯到20世纪40年代的大都会影院进行的翻新。影院坐落于市中心的维亚尔皮亚韦（viale Piave）繁华地段，玛丽亚·卡拉斯（Maria Callas）曾在这里进行歌剧《诺玛》的录制。项目对原建筑进行了全面改造，并扩建1，000平方米左右，现总占地面积约为3，500平方米。可以用于举办各类活动和接待宾客等。设计采用了建筑师和公司共同制定的常见主题：线性结构为主，采用地中海式材料，如浮石和暗乳白玻璃等，表面光鲜亮丽．灯光效果尤佳，完全符合杜嘉班纳（Dolce＆Gabbana）的风格。

关键词：大都会米兰意大利大楼地标建筑占地面积线性结构乳白玻璃

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百子湾公租房

建筑实践 2022年第2期5卷 54-61页

作者：无何晓康郑程文尚立徐琛李广崇王德元郑芳童尚仁 Mujung Kang 张庭辅张龙张凯 Kazushi Miyamoto Yukan Yanagawa 余志鹏 Tomasz Czarnecki davide Signorato Natalia Giacomino Sear Nee 袁铁雯 Steven Chaffer Park Dookee Chung Hiroki Fujino 姜雪竹陈曼 Dina Khaki 杨雪兵 MAD建筑事务所不详

百子湾公租房是MAD建筑事务所的第一个社会住宅项目,MAD希望能够在具体实践中突破常规,用设计推动中国社会住宅创新,让空间和建筑服务于人,使庞大的社区消融于城市和居民的生活,唤醒住宅的社会性,解决目前中国城市快速发展中关于居住的... 详细信息

百子湾公租房是MAD建筑事务所的第一个社会住宅项目,MAD希望能够在具体实践中突破常规,用设计推动中国社会住宅创新,让空间和建筑服务于人,使庞大的社区消融于城市和居民的生活,唤醒住宅的社会性,解决目前中国城市快速发展中关于居住的一系列具体问题。

关键词：公租房建筑事务所社会住宅住宅项目城市快速发展社会性

免疫疗法联合立体定向放疗治疗非小细胞肺癌脑转移:一项AIRO多中心回顾性研究

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中国肺癌杂志 2022年第4期25卷 I0007-I0022页

作者： Silvia SCOCCIANTI Emanuela OLMETTO Valentina PINZI Mattia Falchetto OSTI Rossella Di FRANCO Saverio CAINI Paola ANSELMO Paolo MATTEUCCI davide FRANCESCHINI Cristina MANTOVANI Giancarlo BELTRAMO Francesco PASQUALETTI Alessio BRUNI Paolo TINI Emilia GIUDICE Patrizia CIAMMELLA Anna MERLOTTI Sara PEDRETTI Marianna TRIGNANI Marco KRENGLI NiccolòGIAJ-LEVRA Isacco DESIDERI Guido PECCHIOLI Paolo MUTO Ernesto MARANZANO Laura FARISELLI Pierina NAVARRIA Umberto RICARDI Vieri SCOTTI Lorenzo LIVI 王绿化(翻译/校对) Radiation Oncology Unit Ospedale Santa Maria AnnunziataDepartment of OncologyBagno a RipoliFlorenceItaly Radiation Oncology Unit Azienda Ospedaliero Universitaria CareggiDepartment of Experimental and Clinical Biomedical Sciences"Mario Serio"FlorenceItaly U.O Radioterapia Fondazione IRCCS Istituto Neurologico Carlo BestaDepartment of NeurosurgeryMilanItaly U.O.C Radioterapia A.O.U Sant'Andrea Facolta Medicina e Psicologia Universita SapienzaDepartment of MedicineSurgery and Translational MedicineRomeItaly Istituto Nazionale Tumori IRCCS Fondazione G.PascaleDepartment of RadiotherapyNaplesItaly Institute for Cancer Research Prevention and Clinical Network(ISPRO)Cancer Risk Factors and Life-Style Epidemiology UnitFlorenceItaly Radiotherapy Oncology Center S.Maria HospitalDepartment of OncologyTerniItaly Humanitas Research Hospital Radiotherapy and Radiosurgery DepartmentRozzanoItaly Radiotherapy Unit Department of OncologyTurinItaly Cyberknife Centro Diagnostico Italiano Department of RadiologyMilanItaly Radiation Oncology Azienda Ospedaliero Universitaria PisanaDepartment of Translational MedicinePisaItaly Radiotherapy Unit University Hospital of ModenaDepartment of Oncology and HematologyModenaItaly Radiotherapy Unit University of SienaDepartment of Radiotherapy and OncologySienaItaly UOC di Radioterapia Policlinico Universitario Tor VergataDepartment of Onco-HaematologyRomeItaly Radioterapia Oncologica"G.Prodi "AO-IRCCS Arcispedale S.Maria NuovaDepartment of Oncology and Advanced TechnologyReggio EmiliaItaly Radiation Oncology A.S.O.S.Croce e Carle Department of Radiation OncologyCuneoItaly U.O.Radioterapia Oncologica Department of Radiation OncologyASST Spedali Civili di Brescia e Universita degli studi di BresciaBresciaItaly U.O.C.Radioterapia Oncologica Ospedale Clinicizzato SS Annunziata-Universita Chieti G.D'AnnunzioDepartment of Radiation OncologyChietiItaly Radiation Oncology University Hospital Maggiore della CaritdDepartment of Translational Medicine

背景与目的通过意大利放射治疗和临床肿瘤学学会(Italian Association of Radiotherapy and Clinical Oncology, AIRO)的一项多中心回顾性研究,明确免疫疗法(immunotherapy, IT)和立体定向放疗(stereotactic radiotherapy,SRT)包括放射外科治疗(radiosurgery, RS)或大分割立体定向放疗(hypofractionated stereotactic radiotherapy, HFSRT)治疗非小细胞肺癌(non-small cell lung cancer, NSCLC)脑转移的疗效和毒性。方法对来自19个意大利中心接受SRT+IT的NSCLC伴脑转移患者进行分析,并与单独接受SRT的对照组患者进行比较。结果共纳入SRT+IT组100例和单独SRT组50例。接受SRT+IT的患者有更长的颅内局部无进展生存期(intracranial local progression-free survival, i LPFS)(经倾向性评分调整后,P=0.007)。在诊断为脑转移时接受IT合并有颅外进展的患者中(n=24),接受SRT后再进行IT与较好的总生存期(overall survival, OS)相关(P=0.037)。多因素分析显示组织学类型为非腺癌、卡氏体能状态(Karnofsky performance status,KPS)评分=70分以及接受HFSRT与显著减少的生存期相关(P值分别为0.019、0.017和0.007)。与SRT和IT治疗间隔>7天(n=10)相比,治疗间隔≤7天(n=90)与更长的OS相关(经倾向性评分调整后,P=0.008)。联合治疗耐受性良好。在放射性坏死方面,接受SRT+IT的患者与单独SRT的患者无显著差异。SRT和IT的治疗间隔对毒性发生率无影响。结论 SRT+IT是一种安全的联合治疗方法,与单独SRT相比,具有更长的i LPFS。

关键词：立体定向放疗回顾性研究脑转移倾向性评分临床肿瘤学免疫疗法放射治疗

Negative association between trunk fat, insulin resistance and skeleton in obese women

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World Journal of Diabetes 2013年第2期4卷 31-39页

作者： Emanuela A Greco davide Francomano Rachele Fornari Chiara Marocco Carla Lubrano Vincenza Papa Francesca Wannenes Luigi Di Luigi Lorenzo M Donini Andrea Lenzi Antonio Aversa Silvia Migliaccio Department of Experimental Medicine Section of Medical Pathophysiology Endocrinology and Nutrition University "Sapienza"of Rome Department of Experimental Medicine Section of Medical Pathophysiology Endocrinology and Nutrition University "Sapienza" of Rome Unit of Endocrinology Department of Health Sciences University "Foro Italico" of Rome

AIM: To evaluate the potential interference of trunk fat (TF) mass on metabolic and skeletal metabolism. METHODS: In this cross-sectional study, 340 obese women (mean age: 44.8 ± 14 years; body mass index: 36.0 ± 5.9 kg/m 2 ) were included. Patients were evaluated for serum vitamin D, osteocalcin (OSCA), inflammatory markers, lipids, glucose and insulin (homeostasis model assessment of insulin resistance, HOMA-IR) levels, and hormones profile. Moreover, all patients underwent measurements of bone mineral density (BMD;at lumbar and hip site) and body composition (lean mass, total and trunk fat mass) by dual-energy X-ray absorptiometry. RESULTS: Data showed that: (1) high TF mass was inversely correlated with low BMD both at lumbar (P < 0.001) and hip (P < 0.01) sites and with serum vitamin D (P < 0.0005), OSCA (P < 0.0001) and insulin-like growth factor-1 (IGF-1; P < 0.0001) levels; (2) a positive correlation was found between TF and HOMA-IR (P < 0.01), fibrinogen (P < 0.0001) and erythrocyte sedimentation rate (P < 0.0001); (3) vitamin D levels were directly correlated with IGF-1 (P < 0.0005), lumbar (P < 0.006) and hip (P < 0.01) BMD; and (4) inversely with HOMA-IR (P < 0.001) and fibrinogen (P < 0.0005). Multivariate analysis demonstrated that only vitamin D was independent of TF variable. CONCLUSION: In obese women, TF negatively correlates with BMD independently from vitamin D levels. Reduced IGF-1 and increased inflammatory markers might be some important determinants that account for this relationship.

关键词： Obesity Skeleton Vitamin D Osteocalcin Insulin resistance Trunk fat Inflammation

危机管理中的政府间否决点:面对新冠肺炎疫情的意大利与西班牙

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国际行政科学评论（中文版） 2021年第3期 173-191页

作者：萨尔瓦多·帕拉多达维德·加利(译) 刘晓宇熊缨(审校) 西班牙国立远程教育大学(UNED) 意大利圣心天主教大学中国人事科学研究院人事教育处不详

意大利和西班牙是受新冠肺炎疫情影响的第一批西方国家,在新冠肺炎疫情的第一波爆发中,新型冠状病毒在看起来相似的社会环境中迅速传播——均有相对较多的病例与死亡人数,且采取了相似的严厉封锁措施。两国中央政府陷入了不稳定的政治... 详细信息

意大利和西班牙是受新冠肺炎疫情影响的第一批西方国家,在新冠肺炎疫情的第一波爆发中,新型冠状病毒在看起来相似的社会环境中迅速传播——均有相对较多的病例与死亡人数,且采取了相似的严厉封锁措施。两国中央政府陷入了不稳定的政治平衡中,国家由最近成立的国家政治联盟管理,但这些联盟不仅不断遭受质疑,并且面临着大量的公共债务。两国在行政部门相对于立法部门的作用,以及中央协调和区域离心力之间的紧张关系方面存在差异。为了提高对新冠肺炎疫情如何影响决策和危机管理的理解,本文解释了机构否决点的相关性,以及两个国家之间的差异。通过更多的合作治理,国家能够有空间来对协调、政策能力和共同责任进行匹配。

关键词：问责制新型冠状病毒肺炎意大利西班牙否决点

Production of Aflatoxins from Aspergillus flavus in Liquid Medium

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Journal of Life Sciences 2013年第4期7卷 377-381页

作者： Maria Edite Bezerra da Rocha Francisco das Chagas Oliveira Freire Icaro Gusmao Pinto Vieira Jose Mariados Santos Filho Fabio Erlan Feitosa Maia Maria Izabel Florindo Guedes davide Rondina Universidade Estadual do Ceara Avenida Paranjana 1700 CEP: 60740-000 Fortaleza Ceara Brasil Embrapa Agroindustria Tropical Rua Dra. Sara Mesquita 2270 CEP: 60.511-110 Fortaleza-CE Brasil

Aflatoxins are produced mainly by Aspergillus flavus and Aspergillus parasiticus, and can be found in many grains such as peanuts, soybeans and corn. This study aimed to qualitatively and quantitatively evaluate the production of aflatoxin in liquid media using strains of Aspergillus flavus obtained from peanuts marketed in the city of Fortaleza, CE. Strains of Aspergillus flavus were inoculated into a liquid medium malt extract and after 2 days inoculated into a second medium containing sucrose 5%, MgSO4·7H2O 0.1%, KH2PO4 1%, ZnSO4·7H2O 0.0176 g, and cultured for 3 more days. The media were kept at room temperature ranging from 24 oC to 32 oC with agitation of 130 rpm and aeration of 4.17 L/min. Qualitative analysis was performed by thin layer chromatography and quantitatively by high performance liquid chromatography with fluorescence detection, demonstrating the production of aflatoxin B1 (588 mg/L) and B2 (929 mg/L).

关键词：黄曲霉毒素液体培养基生产高效液相色谱法麦芽提取物薄层色谱法寄生曲霉定量评估