检索结果-南通市图书馆

World Journal of Gastrointestinal Oncology 2018年第12期10卷 522-527页

作者： Jie Chen Lin Du dao-rong wang Department of Gastroenterology Northern Jiangsu Province People’s Hospital Department of Cardiovascular Affiliated Hospital of Yangzhou University

BACKGROUND Mesenteric lymphangioma(ML) in adults is a very rare disease. We report six hospitalized adult patients with ML in our hospital between January 2013 and July 2018 to investigate the characteristics and prognosis of ML in *** SUMMARY The male-to-female ratio was 3:3, and the median age at diagnosis was 55.2 years. Clinical manifestations varied; however, most were acute cases(5/6). No history of trauma was reported. None(0/6) of the patients were accurately diagnosed with ML in the emergency and outpatient departments. Mesenteric cysts were identified in four patients(66.7%) by abdominal ultrasound and in five patients(83.3%) by computed tomography. ML was postoperatively confirmed by pathology. Most MLs(4/6) were associated with infection of other systems. ML was located in the mesentery of the small intestine(n = 4), ileum(n = 1) and rectum(n = 1). Cyst fluid was clear(n = 4), chylous(n = 1) and bloody(n = 1). Surgical procedures included complete tumor removal and partial intestinal excision(n = 6). Recurrence and adhesive intestinal obstruction were not observed during the 3-12 mo follow-up *** ML in adults is a rare benign acquired disease that can be cured by surgical treatment. Infection may be a cause of ML.

关键词： Mesenteric lymphangioma Mesenteric cyst Adults Acute abdominal pain Case report

Safety of fast-track rehabilitation after gastrointestinal surgery:Systematic review and meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第41期20卷 15423-15439页

作者： Liu-Hua wang Chun-Ming Lu Fang Fang dao-rong wang Ping Li Yan wang Department of General Surgery Yizheng People’s Hospital Department of General Surgery Armed Police Corps Hospital of Jiangsu Department of Gastrointestinal Surgery Subei People’s Hospital of Jiangsu Province the First Affiliated Hospital of Yang Zhou University

AIM: To compare the safety of fast-track rehabilitation protocols (FT) and conventional care strategies (CC), or FT and laparoscopic surgery (LFT) and FT and open surgery (OFT) after gastrointestinal surgery.

关键词： Fast-track rehabilitation protocols Laparoscopic surgery Open surgery Enhanced recovery Gastrointestinal surgery Complications Readmission Anastomotic leak Wound infection Obstruction

Impact of postoperative complications on long-term survival after radical resection for gastric cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第25期19卷 4060-4065页

作者： Qing-Guo Li Ping Li Dong Tang Jie Chen dao-rong wang Department of Gastrointestinal Surgery Subei People's Hospital of Jiangsu Province (the First Affiliated Hospital of Yangzhou University)

AIM: To investigate the potential impact of complications in gastric cancer patients who survive the initial postoperative period. METHODS: Between January 1, 2005 and December 31, 2006, 432 patients who received curative gastrectomy with D2 lymph node dissection for gastric cancer at our department were studied. Associations between clinicopathological factors [age, sex, American Society of Anesthesiologists grade, body mass index, tumornode-metastases (TNM) stage and tumor grade], including postoperative complications (defined as any deviation from an uneventful postoperative course within 30 d of the operation and survival rates) and treatment-specific factors (blood transfusion, neoadjuvant therapy and duration of surgery). Patients were divided into 2 groups: with (n = 54) or without (n = 378) complications. Survival curves were compared between the groups, and univariate and multivariate models were conducted to identify independent prognostic factors. RESULTS: Among the 432 patients evaluated, 61 com-plications occurred affecting 54 patients (12.50%).Complications included anastomotic leakages, gastric motility disorders, anastomotic block, wound infections, intra-abdominal abscesses, infectious diarrhea, bleeding, bowel obstructions, arrhythmias, angina pectoris, pneumonia, atelectasis, thrombosis, unexplained fever, delirium, ocular fungal infection and multiple organ failure. American Society of Anesthesiologists grade, body mass index, combined organ resection and median duration of operation were associated with higher post-operative complications. The 1-, 3- and 5-year survival rates were 83.3%, 53.2% and 37.5%, respectively. In the univariate analysis, the size of lesions, TNM stage, blood transfusion, lymphovascular invasion, perineural invasion, neoadjuvant chemotherapy, and postoperative complications were significant predictors of overall survival. In the multivariate analysis, only TNM stage and the presence of complications remained significant p

关键词： Gastric cancer Perioperative complication Surgical resection Complications

Fast-track rehabilitation vs conventional care in laparoscopic colorectal resection for colorectal malignancy: A meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第47期19卷 9119-9126页

作者： Ping Li Fang Fang Jia-Xun Cai Dong Tang Qing-Guo Li dao-rong wang Department of Gastrointestinal Surgery Subei People’s Hospital of Jiangsu Province the First Affiliated Hospital of Yang Zhou University Department of Colorectal Surgery Cancer Hospital Fudan University Department of Oncology Shanghai Medical CollegeFudan University

AIM:To evaluate the fast-track rehabilitation protocol and laparoscopic surgery(LFT)vs conventional care strategies and laparoscopic surgery(LCC).METHODS:Studies and relevant literature comparing the effects of LFT and LCC for colorectal malignancy were identified in MEDLINE,the Cochrane Central Register of Controlled Trials and *** complications and re-admission after approximately 1 mo were ***:Six recent randomized controlled trials(RCTs)were included in this meta-analysis,which related to 655 enrolled *** studies demonstrated that compared with LCC,LFT has fewer complications and a similar incidence of re-admission after approximately 1 *** had a pooled RR of 0.60(95%CI:0.46-0.79,P0.5)for ***:LFT for colorectal malignancy is safe and *** prospective RCTs should be conducted to further compare the efficacy and safety of this approach.

关键词： Laparoscopic surgery Fast-track rehabilitation Enhanced recovery Colorectal surgery Complications Readmission

Safety and efficacy of single-incision laparoscopic surgery for appendectomies: A meta-analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第25期19卷 4072-4082页

作者： Ping Li Zong-Hui Chen Qing-Guo Li Tang Qiao You-Yong Tian dao-rong wang Department of Gastrointestinal Surgery Subei People's Hospital of Jiangsu Province (the First Affiliated Hospital of Yangzhou University) Department of Neurology Nanjing First Hospital (the Third Affiliated Hospital of Nanjing Medical University)

AIM: To compare single incision laparoscopic surgery for an appendectomy (SILS-A) with conventional laparoscopic appendectomy (C-LA) when implemented by experienced surgeons. METHODS: Studies and relevant literature regarding the performance of single-incision laparoscopic surgery vs conventional laparoscopic surgery for appendectomy were searched for in the Cochrane Central Register of Controlled Clinical Trials, MEDLINE, EMBASE and World Health Organization international trial register. The operation time (OR time), complications, wound infection and postoperative day using SILS-A or C-LAwere pooled and compared using a meta-analysis. The risk ratios and mean differences were calculated with 95%CIs to evaluate the effect of SILS-A. RESULTS: Sixteen recent studies including 1624 patients were included in this meta-analysis. These studies demonstrated that, compared with C-LA, SILS-A has a similar OR time in adults but needs a longer OR time in children. SILS-A has similar complications, wound infection and length of the postoperative day in adults and children, and required similar doses of narcotics in children, the pooled mean different of -0.14 [95%CI: -2.73-(-2.45), P > 0.05], the pooled mean different of 11.47 (95%CI: 10.84-12.09, P 0.05), a pooled RR of 1.9 (95%CI: 0.92-3.91, P > 0.05), a pooled RR of 1.01 (95%CI: 0.51-2.0, P > 0.05) a pooled RR of 1.86 (95%CI: 0.77-4.48, P > 0.05), the pooled mean different of -0.25 (95%CI: -0.50-0, P = 0.05) the pooled mean different of -0.01 (95%CI: -0.05-0.04, P > 0.05) the pooled mean different of -0.13 (95%CI: -0.49-0.23, P > 0.05) respectively. CONCLUSION: SILS-A is a technically feasible and reliable approach with short-term results similar to those obtained with the C-LA procedure.

关键词： Single incision Laparoscopy Appendicitis Children Adult

Unusual early-stage pancreatic sarcomatoid carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第43期19卷 7820-7824页

作者： Chuan-Li Ren Ping Jin Chong-Xu Han Qin Xiao dao-rong wang Lin Shi Da-Xin wang Hui Chen Laboratory Medicine and Pathology Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University Pathology Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University Abdominal Surgery Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University Transonogram Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University Laboratory Medicine Centre Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University Geratology Department Northern Jiangsu People’s Hospital and Clinical Medical College of Yangzhou University

Sarcomatoid carcinoma of the pancreas(SCP)is a very rare pathological type of carcinoma that usually has a poor *** pathogenesis has not been *** herein report a case of an early-stage SCP involving successful treatment and a good *** patient was a 48-year-old Chinese man with a5-mo history of vague abdominal *** revealed a 93 mm×94 mm×75 mm mass of mixed echogenicity in the tail of the *** test results were within the normal range,with the exception of an obviously increased pretreatment neuron-specific enolase *** plasma transforming growth factor(TGF)β1 and interleukin-11 levels were obviously increased according to enzyme-linked immunosorbent ***,the excised tumor tissue comprised cancer cells and mesenchymal *** analysis was positive forα-1-antichymotrypsin,pan-cytokeratin,cytokeratin 19,cytokeratin 8/18,and vimentin and negative for CD68and *** pathogenetic mechanism of this case shows that TGFβ1 may regulate the epithelial-tomesenchymal transition in *** early eradication of the tumor and systemic therapy,this patient has been alive for more than 3 years without tumor recurrence or distant *** case is also the first to show that TGFβ1 may regulate the epithelial-tomesenchymal transition in early-stage SCP.

关键词： Sarcomatoid carcinoma of the pancreas Transforming growth factorβ1 Epithelial-to mesenchymal transition Interleukin-11 Vimentin

CD44v6 in peripheral blood and bone marrow of patients with gastric cancer as micro-metastasis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第1期12卷 36-42页

作者： dao-rong wang Guo-Yu Chen Xun-Liang Liu Yi Miao Jian-Guo Xia Lin-Hai Zhu Dong Tang Departmentof General Surgery the First Affiliated Hospital of YangzhouUniversity Yangzhou 225001 Jiangsu Province China Department of General Surgery the First Affiliated Hospital ofNanjing Medical University Nanjing 220029 Jiangsu ProvinceChina

AIM： To detect the expression of CD44 correlated with the ability of micro-metastasis in peripheral blood and bone marrow of patients with gastric cancer and to deduce its clinical significance. METHODS： Preoperative peripheral blood and bone marrow specimens from 46 patients with gastric cancer and 6 controls were studied by semi-quantitative RTPCR amplification of CD44v6mRNA. Preoperative and postoperative peripheral blood specimens from 40 patients with gastric cancer and 14 controls were studied by quantitative RT-PCR amplification of CD44v6mRNA in the corresponding period. RESULTS： Semi-quantitative RT-PCR amplification showed that CD44v6mRNA expression of peripheral blood and bone marrow was positive in 39 （84.8%） and 40 （86.9%） of 46 patients with gastric cancer, respectively. In peripheral blood, CD44v6mRNA expression was positive for diffuse type in 30 （93.8%） of 32 patients and for intestinal type in 9 （64.3%） of 14 patients. On the other hand, in bone marrow, CD44v6mRNA expression was positive for diffuse type in 31 （96.9%） of 32 patients and for intestinal type in 10 （71.4%） of 14 patients. There was a significant difference between the diffuse type and intestinal type. Quantitative RTopCR amplification demonstrated that CD44v6mRNA was not expressed in the peripheral blood of controls and CD44v6mRNA expression was positive for preoperative peripheral blood in 40 patients with gastric cancer, the expression levels being from 4.9 × 10^2 to 3.2× 10^5 copies/g RNA. The average expression level of CD44v6mRNA in peripheral blood was 3.9 × 10^10 copies/g RNA. The expression levels of CD44v6mRNA in peripheral blood in gastric cancer patients after curative operation increased from 5.5 × 100 to 7.6 × 10 copies/g RNA （P = 0.00496）. After curative operation, the expression level decreased markedly. CONCLUSION： Semi-quantitative and quantitative RTPCR amplification for CD44v6mRNA is a sensitive and specific method for the detection of micro-metastasis in periphera

关键词： Gastric cancer Micro-metastasis Peripheral blood Bone marrow CD44v6

Microbiota:a Sword that Breaks Through Diabetes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Nutritional Oncology 2020年第3期5卷 105-115页

作者： Zhu Jiang Dai Jing Qiu Zhang Qi Wu Hui Wen Fang Dong Tang dao rong wang Department of Clinical Medical College Yangzhou UniversityYangzhou 225001JiangsuChina Department of General Surgery Institute of General SurgeryClinical Medical CollegeYangzhou UniversityNorthern Jiangsu People’s HospitalYangzhou 225001JiangsuChina

Diabetes are a group of metabolic disorders characterized by persistent hyperglycemia that is a major public health ***-aged and elderly people are at the highest risk of type 2 diabetes,but younger cases are now being diagnosed with greater *** clinical studies have reported that the behavior of the intestinal microbiota may affect the development of metabolic disorders in humans,including obesity and *** review describes the relationship between the gut microbiota and diabetes,and discusses the possible mechanisms underlying their involvement in the development of type 1 diabetes,obesity,and type 2 *** better understanding the intestinal microbiota,it may become possible to treat diabetes and obesity by manipulating the gut microbes through probiotics and dietary changes,fecal microbiota transplantation,or surgical approaches.

关键词： Microbiota Type 1 diabetes Type 2 diabetes Obesity Inflammation Probiotics Fecal microbial transplantation Roux-En-Y gastric bypass Sleeve gastrectomy

Overexpression of lysine specific demethylase 1 predicts worse prognosis in primary hepatocellular carcinoma patients

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第45期18卷 6651-6656页

作者： Ze-Kun Zhao Hai-Feng Yu dao-rong wang Ping Dong Lei Chen Wen-Guang Wu WenJun Ding Ying-Bin Liu Department of General Surgery Xinhua Hospital Affiliated to Shanghai Jiaotong University Department of General Surgery Yixing People's Hospital Department of General Surgery Northern Jiangsu People's Hospital

AIM:To investigate the clinicopathological features and prognostic value of lysine specific demethylase 1(LSD1) in hepatocellular carcinoma(HCC).METHODS:We examined LSD1 expression in 60 paired liver cancer tissues and adjacent noncancerous tissues by quantitative real time polymerase chain reaction(qRT-PCR) and Western *** addition,we analyzed LSD1 expression in 198 HCC samples by *** relationship between LSD1 expression,clinicopathological features and patient survival was ***:Immunohistochemistry,Western blotting,and qRT-PCR consistently confirmed LSD1 overexpression in HCC tissues compared to adjacent non-neoplastic tissues(P < 0.01).Additionally,immunostaining showed more LSD1-positive cells in the higher tumor stage(T3-4) and tumor grade(G3) than in the lower tumor stage(T1-2,P < 0.001) and tumor grade(G1-2,P < 0.001),***,HCC patients with high LSD1 expression had significantly lower 5-year overall survival rates(P < 0.001) and lower 5-year disease-free survival rates(P < 0.001),respectively.A Cox proportional hazards model further demonstrated that LSD1 over-expression was an independent predictor of poor prognosis for both 5-year disease-free survival [hazards ratio(HR) = 1.426,95%CI:0.672-2.146,P < 0.001] and 5-year overall survival(HR = 2.456,95%CI:1.234-3.932,P < 0.001) in ***:Our data suggest for the first time that the overexpression of LSD1 protein in HCC tissues indicates tumor progression and predicts poor prognosis.

关键词： Hepatocellular carcinoma Lysine specificdemethylase 1 Tumor progression Prognosis

The Value of a Modified Colonic Transit Test in the Diagnosis of Chronic Constipation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Nutritional Oncology 2022年第3期7卷 153-160页

作者： Yu Ji Chen Bin Zhao Yi Qun Liao Chen Wei Yi Chao Ma Fei wang dao rong wang Dong Tang Department of General Surgery Clinical Medical CollegeYangzhou UniversityYangzhou 225001JiangsuChina Department of General Surgery The Yangzhou School of Clinical Medicine of Dalian Medical UniversityDalian 116044LiaoningChina Department of General Surgery Institute of General SurgeryClinical Medical CollegeYangzhou UniversityNorthern Jiangsu People's HospitalYangzhou 225001JiangsuChina

Objectives To explore the value of performing a modified colonic transit test in the diagnosis of chronic *** we retrospectively analyzed the results in 101 patients admitted to the MDT Outpatient Clinic of Subei People’s Hospital,Jiangsu Province,China,from July 1,2019,to July 31,*** were prohibited from using drugs and stimulant foods that could affect bowel motility for three days before and during the *** performed two abdominal X-rays at 6 and 72 hours after oral ingestion of the barium suspension to observe the residual condition of barium in the patient's *** then gave specific treatments based on the different types of constipation detected in the *** Compared with patients with normal transit,patients with slow transit(P<0.001)and patients with rectal evacuation disorders had a significantly reduced stool frequency(P<0.05).The kappa coefficient of the modified colonic transit test compared to anorectal manometry in the diagnosis of functional defecation disorders(FDDs)was 0.649,indicating substantial consistency between the two *** The modified colonic transit test not only assesses colonic transit function and provides an initial determination of the type of constipation,but also shows the colon morphology,providing a reference for possible subsequent treatments.

关键词： Chronic constipation Colonic transit test Radiopaque markers Barium suspension Abdominal plain film