Safety of fast-track rehabilitation after gastrointestinal surgery:Systematic review and meta-analysis

作     者：Liu-Hua Wang Chun-Ming Lu Fang Fang Dao-Rong Wang Ping Li Yan Wang 

作者机构：Department of General SurgeryYizheng People’s Hospital Department of General SurgeryArmed Police Corps Hospital of Jiangsu Department of Gastrointestinal SurgerySubei People’s Hospital of Jiangsu Province the First Affiliated Hospital of Yang Zhou University 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第41期

页      面：15423-15439页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：Supported by The National Natural Science Foundation of China No.81172279 

主　　题：Fast-track rehabilitation protocols Lapa-roscopic 

摘      要：AIM:To compare the safety of fast-track rehabilitation protocols(FT) and conventional care strategies(CC),or FT and laparoscopic surgery(LFT) and FT and open surgery(OFT) after gastrointestinal ***:We searched MEDLINE,WHO International Trial Register,Embase and The Cochrane Central Register of Controlled Trials up to 2014 for randomized controlled trials(RCTs) comparing FT and CC or comparing LFT and OFT,with 10 or more randomized participants and about 30 d *** reviewers independently extracted data on complications,anastomotic leak,obstruction,wound infection,re-admission between FT and CC or LFT and OFT after gastrointestinal ***:Twenty-four RCTs of FT vs CC or LFT vs OFT were *** with CC,FT reduced overall complications and wound ***,anastomotic leak,obstruction and re-admission were not significantly *** pooled risk ratio(RR) of 0.69(95%CI:0.60-0.78; P 0.05),a pooled RR of 0.87(95%CI:0.67-1.15; P 0.05) and pooled RR of 0.94(95%CI:0.73-1.22; P 0.05) *** with OFT,LFT reduced complications,with a pooled RR of 0.66(95%CI:0.54-0.81; P 0.001).CONCLUSION:FTs are safe after gastrointestinal *** large,prospective RCTs should be conducted to establish further the safety of this approach.