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Multimodal cardiac imaging assisted tumor characterization and surgical planning of a patient with rare primary cardiac paraganglioma

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Journal of Geriatric Cardiology 2024年第2期21卷 246-250页

作者： shu-Yu MENG Li-Qun WANG Hao-dan danG Lin ZHANG sheng-Li JIANG Bo-Han LIU Department of Ultrasound Diagnosis the First Medical CenterChinese PLA General HospitalBeijingChina Department of Nuclear Medicine the First Medical CenterChinese PLA General HospitalBeijingChina Department of Pathology the First Medical CenterChinese PLA General HospitalBeijingChina Department of Cardiovascular Surgery the First Medical CenterChinese PLA General HospitalBeijingChina

Paragangliomas,also known as pheochromocytomas(1–9 cases per million),arise in the paraganglia.[1]Pheochromocytomas occur in the adrenal glands,while paragangliomas occur elsewhere.[2]Paragangliomas originate from paraganglion cells,which are derived from the neural ectoderm of the nerves and migrate along both sides of the median axis from the base of the skull to the pelvis during embryonic development.

关键词： glioma cardiac nerves

Microphase Separation of Semiflexible Ring Diblock Copolymers

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Chinese Journal of Polymer Science 2024年第2期42卷 267-276,I0011页

作者： dan-Yan Qin sheng-Da Zhao Zhi-Xin Liu Jing Zhang Xing-Hua Zhang School of Physical Science and Engineering Beijing Jiaotong UniversityBeijing100044China

Aiming at the difficult problem of solving the conformation statistics of complex polymers, this study presents a novel and concise conformation statistics theoretical approach based on Monte Carlo and Neural Network method. This method offers a new research idea for investigating the conformation statistics of complex polymers, characterized by its simplicity and practicality. It can be applied to more complex topological structure, more higher degree of freedom polymer systems with higher dimensions, theory research on dynamic self-consistent field theory and polymer field theory, as well as the analysis of scattering experimental data. The conformation statistics of complex polymers determine the structure and response properties of the system. Using the new method proposed in this study, taking the semiflexible ring diblock copolymer as an example, Monte Carlo simulation is used to sample this ring conformation to construct the dataset of polymer. The structure factor describing conformation statistics are expressed as continuous functions of structure parameters by neural network supervised learning. This is the innovation of this work. As an application, the structure factors represented by neural networks were introduced into the random phase approximation theory to study the microphase separation of semiflexible ring diblock copolymers. The influence of the ring's topological properties on the phase transition behavior was pointed out.

关键词： Ring copolymer Diblock copolymers Semiflexible The order-disorder transition

Aflatoxin B1 decreased flesh flavor and inhibited muscle development in grass carp(Ctenopharyngodon idella)

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Animal Nutrition 2024年第3期18卷 27-38页

作者： Xiang Ning He Zhen Zhen Zeng Wei dan Jiang Pei Wu Yang Liu sheng Yao Kuang Ling Tang shu Wei Li Lin Feng Xiao Qiu Zhou Animal Nutrition Institute Sichuan Agricultural UniversityChengdu 611130China Fish Nutrition and Safety Production University Key Laboratory of Sichuan Province Sichuan Agricultural UniversityChengdu 611130China Key Laboratory for Animal Disease-Resistance Nutrition Ministry of EducationMinistry of Agriculture and Rural AffairsKey Laboratory of Sichuan ProvinceChengdu 611130China Animal Nutrition Institute Sichuan Academy of Animal ScienceChengdu 610066China

In nature,aflatoxins,especially aflatoxin B1(AFB1),are the common mycotoxins,which cause serious health problems for humans and *** paper aimed to study the effects of AFB1 on flesh flavor and muscle development of grass carp(Ctenopharyngodon idella)and its *** were 1440 individual fish in total,with 6 treatments and each treatment replicated 3 *** 6 treatments were fed a control diet with different doses of AFB1(0.04,29.48,58.66,85.94,110.43 and 146.92μg/kg diet)for 60 ***1 increased myofiber diameter,as well as decreased myofiber density of grass carp muscle(Pdant enzyme(glutathione peroxidase,glutathione,glutathione reductase,total antioxidant capacity,anti-superoxide anion,and anti-hydroxyl radical)were decreased(P<0.05)with the dietary AFB1 *** addition,dietary AFB1 decreased the content of collagen,and downregulated the mRNA and protein levels of transforming growth factor-β(TGF-β)/Smads signaling pathway in grass carp muscle(P<0.05).The mRNA and protein levels of myogenic regulatory factors were downregulated in grass carp muscle(P<0.05).Furthermore,the activities of matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-9(MMP-9)were increased(P<0.05),and the protein levels of phosphorylate-38 mitogen-activated protein kinase(p-p38MAPK),phosphorylate-c-Jun N-terminal kinase,urokinase-type plasminogen activator(uPA),MMP-2 and MMP-9 were upregulated(P<0.05),but collagenⅠ,lamininβ1 and fibronectin were downregulated(P<0.05)with the dietary AFB1 increased in the muscle of grass *** on the results of this study,we can draw the following conclusion:dietary AFB1 might damage flesh flavor and inhibit the muscle development through MAPK/uPA/MMP/extrac

关键词： Aflatoxin B1 Flesh flavor Muscle development Grass carp

Energy saving analysis for CO_(2)–O_(2)mixed injection technology in converter steelmaking

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Journal of Iron and Steel Research International 2024年第5期31卷 1095-1103页

作者： Bao-chen Han Chun-liang Gao Ya-qiang Li dan Liu Guang-sheng Wei Rong Zhu Hebei Key Laboratory of Material Near-Net Forming Technology School of Material Science and EngineeringHebei University of Science and TechnologyShijiazhuang050018HebeiChina Department of Automotive Engineering Hebei Vocational University of Technology and EngineeringXingtai054000HebeiChina School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing100083China

Energy-saving in China's iron and steel industry still relies on the development and improvement of short-term energy saving ***,a special converter smelting technology incorporating energy saving was *** evaluate the energy-saving potential of the CO_(2)–O_(2)mixed injection(COMI)technology,collected production data were used to develop an improved techno-economic *** reveal that the technology can save energy through auxiliary material consumption,sensible heat of solid by-product,iron loss reduction,and energy *** application of COMI technology in an enterprise is cost effective,involving the energy saving potential of 0.206 GJ/t,the cost of conserved energy of−48.83 yuan/GJ,and a simple payback period of 0.35 year for a 60-million-yuan *** analysis shows that the investment cost and discount rate primarily influence the cost of conserved energy of the *** the discount rate increased,the cost of conserved energy also gradually ***,the COMI technology is an energy-saving technology with good development prospects.

关键词： Converter steelmaking COMI technology Energy saving Techno-economic model Investment cost

Vibration Suppression for Active Magnetic Bearings Using Adaptive Filter with Iterative Search Algorithm

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CES Transactions on Electrical Machines and Systems 2024年第1期8卷 61-71页

作者： Jin-Hui Ye dan Shi Yue-sheng Qi Jin-Hui Gao Jian-Xin Shen IEEE Department of Electrical Engineering Zhejiang UniversityHangzhou 310027China CES and IEEE

Active Magnetic Bearing(AMB) is a kind of electromagnetic support that makes the rotor movement frictionless and can suppress rotor vibration by controlling the magnetic force. The most common approach to restrain the rotor vibration in AMBs is to adopt a notch filter or adaptive filter in the AMB controller. However, these methods cannot obtain the precise amplitude and phase of the compensation current. Thus, they are not so effective in terms of suppressing the vibrations of the fundamental and other harmonic orders over the whole speed range. To improve the vibration suppression performance of AMBs,an adaptive filter based on Least Mean Square(LMS) is applied to extract the vibration signals from the rotor displacement signal. An Iterative Search Algorithm(ISA) is proposed in this paper to obtain the corresponding relationship between the compensation current and vibration signals. The ISA is responsible for searching the compensating amplitude and shifting phase online for the LMS filter, enabling the AMB controller to generate the corresponding compensation force for vibration suppression. The results of ISA are recorded to suppress vibration using the Look-Up Table(LUT) in variable speed range. Comprehensive simulations and experimental validations are carried out in fixed and variable speed range, and the results demonstrate that by employing the ISA, vibrations of the fundamental and other harmonic orders are suppressed effectively.

关键词： Active Magnetic Bearing(AMB) Adaptive filter Iterative search algorithm Least mean square(LMS) Vibration suppression

A small D-A molecule with highly heat-resisting room temperature phosphorescence for white emission and anti-counterfeiting

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Ti_(3)C_(2)T_(x)/SnO_(2)P–N heterostructure construction boosts room-temperature detecting formaldehyde

结构化学 2024年第3期43卷 3-9页

作者： Kun Zhang Ni dan dan-dan Ren Ruo-Yu Zhang Xiaoyan Lu Ya-Pan Wu Li-Lei Zhang Hong-Ru Fu Dong-sheng Li College of Materials and Chemical Engineering China Three Gorges UniversityYichang443002PR China College of Chemistry and Chemical Engineering Luoyang Normal UniversityLuoyang471934PR China College of Chemistry and Chemical Engineering Luoyang Normal UniversityLuoyang471934PR China College of Materials and Chemical Engineering China Three Gorges UniversityYichang443002PR China

Achieving high heat-resisting room temperature phosphorescence(RTP)performance and robust white emission from pure small molecules is a meaningful but challenging ***,a simple donor-acceptor(D-A)molecule,9-(1H-benzotriazol-1-ylmethyl)-9H-carbazole(CzBtrz),was *** simple molecule not only exhibits multiple emissions including white light,thermally activated delayed fluorescence(TADF)and ultralong RTP with a lifetime of 988.54 ms at 545 nm,but also shows superhigh heat-resisting phosphorescence property which can maintain stability in a large temperature region from 77 to 350 K(ΔT=273 K),exceeding those of other RTP ***,this molecule shows the time-evolved dynamic *** experimental and theoretical an-alyses from CzBtrz crystal demonstrate that the intramolecular charge transfer(ICT)interaction and molecular stacking play an important role in the generation of ***,this work provides an efficient strategy to design ultrahigh heat-resistant RTP,ultralong RTP and single-phased white-light emitting materials.

关键词： Ultralong RTP TADF D-A molecule Heat-resisting White light

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Rare Metals 2024年第1期43卷 267-279页

作者： Yue Zhang Ming-Yue Wang Xiao-Guang San Yan-Bai Shen Guo-sheng Wang Lei Zhang dan Meng College of Chemical Engineering Shenyang University of Chemical TechnologyShenyang 110142China Institute for Superconducting and Electronic Materials(ISEM) Australian Institute for Innovative Materials(AIIM)University ofWollongongWollongongNSW2500Australia College of Resources and Civil Engineering Northeastern UniversityShenyang 110819China

Formaldehyde is a common atmospheric pollutant produced in industrial production and daily ***,the traditional semiconductor formaldehyde gas sensor cannot work at room temperature,which limits its practical ***,developing high-performance gas sensors for rapidly and accurately detecting formaldehyde at room temperature is an important *** this study,Ti_(3)C_(2)Tx/SnO_(2)heterostructures were constructed,which could selectively detect formaldehyde at room temperature with a response value of 29.16%(10×10^(-6)).In addition,the sensor shows a remarkable theoretical detection limit of 5.09×10^(-9)and good longterm *** functional theory(DFT)simulations reveal that SnO_(2)nano spheres provide the majority of adsorption sites that strongly interact with ***,Ti_(3)C_(2)T_(x)acting as a conductive layer facilitates the transfer of charge carriers so that they show a sensing response to formaldehyde at room ***,the formation of p-n heterostructures between SnO_(2)and Ti_(3)C_(2)T_(x)boosts the Schottky barrier at the interface,which is the critical factor in enhancing the sensing properties by turning the Schottky barrier upon introducing formaldehyde *** perspective is expected to provide instructive guidance for utilizing MXene/metal oxide nanocomposites to improve the gas sensing performance at room temperature.

关键词： Ti_(3)C_(2)T_(x)/SnO_(2)nanocomposites p-n heterostructures Formaldehyde sensing Room temperature DFT calculations

Association between glaucoma and stroke:A bidirectional mendelian randomization study

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Advances in Ophthalmology Practice and Research 2024年第3期4卷 147-155页

作者： Kai Wang Xueqi Lin Siting sheng dan Chen Xin Liu Ke Yao Eye Center of the Second Affiliated Hospital Zhejiang University School of MedicineHangzhouChina Department of Ophthalmology Zhongshan HospitalFudan UniversityShanghaiChina Shanghai Institute of Infectious Disease and Biosecurity Zhongshan HospitalFudan UniversityShanghaiChina

Purpose:Observational studies have reported positive associations between glaucoma and stroke;however,controversial results ***,the nature of the relationship remains unknown since previous studies were not designed to test ***,we aimed to investigate the possible causal relationships between glaucoma and ***:Our two-sample Mendelian randomization(MR)encompassed multi-ethnic large-scale genome-wide association studies with more than 20000 cases and 260000 controls for glaucoma,and more than 80000 cases and 630000 controls for *** effect estimates for each SNP were combined using the inverse-variance weighted(IVW)*** avoid potential pleiotropic effects,we adjusted the main results by excluding genetic variants associated with metabolic *** weighted median and MR-Egger methods were also used for the sensitivity ***:Our MR analysis revealed that glaucoma and its subtypes,including primary open-angle glaucoma and primary angle-closure glaucoma,exhibited no causal role in relation to any stroke(AS),any ischemic stroke(AIS),large-artery atherosclerotic stroke(LAS),small-vessel stroke(SVS),or cardioembolic stroke(CES)across MR analyses(all P>0.05).The null associations remained robust even after adjusting for metabolic-related traits and were consistent in both the European and Asian ***,reverse MR analyses also did not indicate any significant causal effects of AS,AIS,LAS,or CES on glaucoma ***:Evidence from our series of causal inference approaches using large-scale population-based MR an-alyses did not support causal effects between glaucoma and *** findings suggest that the relationship of glaucoma management and stroke risk prevention should be carefully evaluated in future *** turn,stroke diagnosis should not be simply applied to glaucoma risk prediction.

关键词： Glaucoma Stroke Mendelian randomization Causation Metabolic-related trait

Streptococcus anginosus in the development and treatment of precancerous lesions of gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3771-3780页

作者： Su-Ting Qian Hao-Yu Zhao Fei-Fei Xie Qing-sheng Liu dan-Li Cai Department of Digestive Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina Science and Education Section Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical UniversityHangzhou 310007Zhejiang ProvinceChina Intensive Care Unit The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou 311122Zhejiang ProvinceChina

The microbiota is strongly association with *** have shown significant differences in the gastric microbiota between patients with gastric cancer(GC)patients and noncancer patients,suggesting that the microbiota may play a role in the development of *** Helicobacter pylori(***)infection is widely recognized as a primary risk factor for GC,recent studies based on microbiota sequencing technology have revealed that *** microbes also have a significant impact on GC.A recent study discovered that Streptococcus anginosus(***)is more prevalent in the gastric mucosa of patients with GC than in that of those without *** infection can spontaneously induce chronic gastritis,mural cell atrophy,mucoid chemotaxis,and heterotrophic hyperplasia,which promote the development of precancerous lesions of GC(PLGC).*** also disrupts the gastric barrier function,promotes the proliferation of GC cells,and inhibits ***,*** is underrepresented in the *** reports suggest that it may cause precancerous lesions,indicating its emerging *** novel molecular diagnostic techniques,such as polymerase chain reaction,genetic testing,and Ultrasensitive Chromosomal Aneuploidy Detection,can be used to gastric precancerous lesions via microbial ***,we present a concise summary of the relationship between *** and *** aim was to further investigate new methods of preventing and treating PLGC by exploring the pathogenicity of *** on PLGC.

关键词： Streptococcus anginosus Gastric cancer Precancerous lesions of gastric cancer Microbiota Microbiota sequencing technology