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肝星形细胞的研究进展

解剖学报 2010年第2期41卷 323-325页

作者：张永晶徐存拴河南师范大学生命科学学院河南省-科技部共建细胞分化调控国家重点实验室培育基地河南新乡453007

肝星形细胞(HSCs)是肝脏中具有储存脂质特别是维生素A、合成细胞外基质、调节肝窦微循环等功能的非肝实质细胞,它们与多种肝脏疾病,特别是肝纤维化密切相关。我们简要总结了近几年有关肝星形细胞的分离、鉴定、增殖及增殖调控、在肝再... 详细信息

肝星形细胞(HSCs)是肝脏中具有储存脂质特别是维生素A、合成细胞外基质、调节肝窦微循环等功能的非肝实质细胞,它们与多种肝脏疾病,特别是肝纤维化密切相关。我们简要总结了近几年有关肝星形细胞的分离、鉴定、增殖及增殖调控、在肝再生、肝病等中作用的研究进展。

关键词：肝星形细胞肝再生肝纤维化细胞分离鉴定

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宋金元时期心悸病证治特点探析

天津中医药 2024年第5期41卷 575-581页

作者：王哲高利东徐存王保和天津中医药大学第一附属医院天津300381 国家中医针灸临床医学研究中心天津300381 天津中医药大学天津301617

宋金元时期心悸病的证治理论得到极大的丰富和完善。北宋时期,心悸病的发展多承晋唐“类分”思想之遗风,医家们注重对前朝医药理论的整理和继承,但又有所发挥。北宋医者新提出时气热毒、热邪两种病因,补入心实热、心中风和肾虚3种脏腑证... 详细信息

宋金元时期心悸病的证治理论得到极大的丰富和完善。北宋时期,心悸病的发展多承晋唐“类分”思想之遗风,医家们注重对前朝医药理论的整理和继承,但又有所发挥。北宋医者新提出时气热毒、热邪两种病因,补入心实热、心中风和肾虚3种脏腑证型,扩充了他病致悸的种类,心悸的通用药物被首次提出,历代效验方在方书中也得到全面的总结和整理。南宋时期,医家们受理学影响本经典、重求理,对心悸的病名和分类方式进行规范,发挥火热、脾胃气虚、血虚、气郁、痰浊等病机,并对心悸方剂进行精简,创立诸多名方,同时注重用药的次第问题,丰富了心悸的治法治则。纵观宋金元时期,心悸病的部分用药存在古今变迁,需要给予足够的重视;对病机的理解及治法用药亦与当代不同,值得学习与借鉴。

关键词：宋金元时期心悸中医证治特点

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库普弗细胞的研究进展

解剖学报 2010年第2期41卷 331-332页

作者：张强伟徐存拴河南师范大学生命科学学院河南省-科技部共建细胞分化调控国家重点实验室培育基地河南新乡453007

库普弗细胞(KCs)是肝脏的非实质细胞。具有分泌细胞因子及吞噬、免疫等功能,亦与多种肝脏疾病,如肝损伤、肝纤维化、肝硬化等密切相关。本文简要总结了近几年有关库普弗细胞的生理功能及与肝病关系等方面的研究进展。

关键词：库普弗细胞细胞因子

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肝陷窝细胞的研究进展

解剖学报 2010年第2期41卷 326-327页

作者：和春肖徐存拴河南师范大学生命科学学院河南省-科技部共建细胞分化调控国家重点实验室培育基地河南新乡453007

肝陷窝细胞(PCs)是肝脏的自然杀伤细胞(HNKCs),具有抗肿瘤、抗病毒、调节肝细胞的生长、分化、抑制肝纤维化等作用。本文简要地总结了近几年肝陷窝细胞的研究进展。

关键词：肝脏陷窝细胞自然杀伤细胞

3D entangled fractional squeezing transformation and its quantura mechanical correspondence

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Frontiers of physics 2016年第3期11卷 81-87页

作者： Fang Jia shuang xu Cheng-Zhi Deng cun-Jin Liu Li-Yun Hu Center for Quantum Science and Technology Jiangxi Normal University Nanchan9 330022 China Department of Material Science and Engineering University of Science and Technology of China Hefei 230026 China School of Information Engineering Nanchang Institute of Technology Nanchang 330099 China

A new type of entangled fractionaJ squeezing transformation （EFrST） has been theoretically pro- posed for 2D entanglement [Front. Phys. 10, 100302 （2015）]. In this paper, we shall extend this case to that of 3D entanglement by introducing a type of three-mode entangled state representation, which is not the product of tkrec 1D cases. Using the technique of integration within an ordered product of operators, we derive a compact unitary operator corresponding to the 3D fractional entangling transformation, which is an entangling operator that presents a clear transformation re- lation. We also verified that the additivity property of the novel 3D EFrST is of a Fourier character by using its quantum mechanical description. As an application of this representation, the EFrST of the three-mode number state is calculated using the quantum description of the EFrST.

关键词： entangled fractional squeezing transformation entangled state representation

Amphiphilic poly(ethylene glycol)-b-poly(ethylene brassylate)copolymers: One-pot synthesis, self-assembly, and controlled drug release

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Chinese Chemical Letters 2015年第10期26卷 1319-1321页

作者： Jiu-cun Chen Jun-Zhi Li Jian-Hua Liu Li-Qun xu Institute for Clean Energy & Advanced Materials Southwest University State Key Laboratory of Medicinal Chemical Biology Nankai University Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies

A set of amphiphilic poly（ethylene glycol）-b-poly（ethylene brassylate）（PEG-b-PEB） copolymers based on the PEB hydrophobic block was first synthesized by ring-opening polymerization of ethylene brassylate with an organic catalyst. The EB/PEG molar ratios and reaction times were adjusted to achieve different chain lengths of PEB. Block copolymers that were characterized by1 H NMR and GPC could selfassemble into multimorphological aggregates in aqueous solution, which were characterized by DLS and TEM. The hydrophobic doxorubicin（DOX） was chosen as a drug model and successfully encapsulated into the nanoparticles. The release kinetics of DOX were investigated.

关键词： Poly(ethylene brassylate) Self-assembly Nanoparticles Controlled drug release

基于GWO-BPNN早期带伤混凝土冻后力学性能影响研究

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水电能源科学 2024年第9期42卷 93-97页

作者：徐存东曹骏陈家豪田俊姣韩文浩汪志航华北水利水电大学水利学院河南郑州450046 浙江省农村水利水电资源配置与调控关键技术重点实验室浙江杭州310018

为探究西北寒旱区水工混凝土结构早期受冻损伤后力学性能衰退的损伤规律和影响因素,设计混凝土早期受冻及冻融循环的室内加速试验,通过对混凝土试样进行冻融循环,探究温度为-10℃,起冻时刻为3.5 h的混凝土结构冻融损伤的劣化规律,研究... 详细信息

为探究西北寒旱区水工混凝土结构早期受冻损伤后力学性能衰退的损伤规律和影响因素,设计混凝土早期受冻及冻融循环的室内加速试验,通过对混凝土试样进行冻融循环,探究温度为-10℃,起冻时刻为3.5 h的混凝土结构冻融损伤的劣化规律,研究水胶比、粉煤灰和引气剂对早期带伤混凝土冻后力学性能的影响。构建灰狼优化算法改进的反向传播神经网络(GWO-BPNN)对早期带伤混凝土的力学性能及抗冻性能进行模拟预测,并对各影响因素进行敏感性分析。结果表明,低水胶比混凝土的抗冻效果明显更优,引气剂可提升早期抗冻性能,最佳掺量为0.01%,粉煤灰在冻融循环后期对混凝土抗冻性有明显的提高,其最佳替代量为20%;GWO-BPNN模型的四个回归评估指标均优于传统神经网络模型,能够更准确地预测早期带伤混凝土的力学性能,影响早期带伤混凝土耐久性的最大变量为水胶比,最小变量为引气剂。

关键词：灰狼优化算法神经网络早期带伤混凝土抗压强度影响因子分析

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Positron emission tomography/computerized tomography in the evaluation of primary non-Hodgkin's lymphoma of prostate

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World Journal of Gastroenterology 2013年第39期19卷 6699-6702页

作者： Bo Pan Jian-Kui Han Shi-cun Wang Ao xu PET/CT Center Qilu Hospitalthe First Affiliated Hospital of Shandong University PET/CT Center Affiliated Anhui Provincial Hospital of Anhui Medical University Department of Pathology Affiliated Anhui Provincial Hospital of Anhui Medical University

Primary malignant lymphoma of the prostate is exceedingly *** we report a case of a 65-year-old man who presented with increased urinary frequency,urinary urgency,and urinary incontinence for two *** prostatic hypertrophy was suspected at primary *** revealed a hypoechoic lesion of the *** total serum prostate-specific antigen was within normal *** emission tomography/computerized tomography(PET/CT)showed a hypermetabolic prostatic *** biopsy was consistent with a non-germinal center diffuse large B cell *** was complete remission of the prostatic lesion following six cycles of chemotherapy as shown on the second PET/CT imaging.18F-fluoro-deoxy glucose PET/CT is not only a complement to conventional imaging,but also plays a significant role in the diagnosis and evaluation of treatment response of prostatic lymphoma.

关键词： Fluoro-Deoxy-Glucose Positron emission tomography/computerized tomography Non-Hodgkin’s lymphoma Prostatic lymphoma Evaluation

Tribology of rotating band and gun barrel during engraving process under quasi-static and dynamic loading

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Friction 2014年第4期2卷 330-342页

作者： Bin WU Jing ZHENG Qing-tao TIAN Zhi-qiang ZOU xu-hua YU Kai-shuan ZHANG Army Officer Academy PLA No.451 Huangshan RoadHefei CityAnhui Province230031China

The engraving process of a projectile rotating band is one of the most basic research aspects in interior ballistics,which has not been thoroughly understood thus *** understanding of this process is of great importance from the viewpoints of optimal design,manufacturing,use,and maintenance of gun and *** this paper,the interaction of copper and nylon rotating bands with a CrNiMo gun barrel during engraving was studied under quasi‐static and dynamic loading *** quasi‐static engraving tests were performed on a CSS‐88500 electronic universal testing machine(EUTM)and a special gas‐gun‐based test rig was designed for dynamic impact engraving of the rotating *** mechanical behaviors of copper and nylon were investigated under strain rates of 10^(−3) s^(−1) and 2×10^(3) s^(−1) using an MTS 810 and a split Hopkinson pressure bar(SHPB),*** of the worn surfaces and cross‐sectional microstructures were observed with scanning electron microscope(SEM)and optical microscope(OM).It was found that large deformation and severe friction occur during *** surface layer is condensed and correlated with a hardness gradient along the depth from the top worn *** structure of the rotating band and gun bore,band material,and loading rate have great effects on band *** flow stress‐strain of the copper strongly depends on the applied strain *** is suggested that strain rate and temperature play significant roles in the deformation mechanism of rotating bands.

关键词： tribology sliding friction plastic deformation rotating band gun barrel engraving strain rate