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崔林华五线七针运动疗法治疗脑卒中后肢体运动功能障碍探析

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河北中医药学报 2022年第6期37卷 33-37页

作者：闫泽昊高婷崔林华齐丛会刘山山段英民华北理工大学中医学院唐山063000 河北省人民医院石家庄050051

脑卒中是临床最为常见的脑血管疾病,发病率高,后遗症多,其中肢体运动功能障碍是影响患者生命健康和生活质量重要因素。崔林华主任中医师在焦氏头针、方氏头针和国标头针的长期应用基础上,结合临床开颅术后或头皮损伤患者存在取穴遇阻等... 详细信息

脑卒中是临床最为常见的脑血管疾病,发病率高,后遗症多,其中肢体运动功能障碍是影响患者生命健康和生活质量重要因素。崔林华主任中医师在焦氏头针、方氏头针和国标头针的长期应用基础上,结合临床开颅术后或头皮损伤患者存在取穴遇阻等实际难题,经过多年摸索、总结,创新性的提出了五线七针运动疗法治疗脑卒中后肢体运动功能障碍。该针法主要采用头部创新用穴、久留针刺、针刺运动、毫针点刺等方法,扩大了头针的覆盖面积,增加了对病灶侧脑部的影响,并不同程度避开了头皮损伤区域,通过适当延长留针时间和主被动运动,促进肢体恢复,具有操作简便、疗效突出、安全可靠的优势,目前在治疗脑卒中后肢体运动功能障碍方面疗效较佳。

关键词：五线七针针刺运动脑卒中中风肢体运动障碍崔林华取穴遇阻机理探析

CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng Wang Guo-cui Mao Hui-lin Jiang Bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： CO 2 methanation Metal hydride Ni catalysts Carbonate Metal-carbonate interface

Deciphering the role of mtH2O2 in hepatic ischemia-reperfusion injury mechanisms with low-background super-resolution fluorogenic probe

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Science China Chemistry 2025年第1期68卷 297-307页

作者： Bin Fang Limin Wang Haoqin Li Jiaxin Zhang Yang Ding Pan Pan Li Bo Peng hua Bai lin Li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

关键词： hepatic ischemia-reperfusion injury low-background mtH2O2-activatable super-resolution imaging fluorogenic probe

Efficacy comparison of different forms of dog-days acupoint application for prevention and treatment of chronic bronchitis

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Journal of Acupuncture and Tuina Science 2019年第3期17卷 168-173页

作者： Liu Yang cui lin-hua Li Qing Xing Xiao Qi Cong-hui Wang Shao-jin Lv Ying Hebei University of Chinese Medicine Shijiazhuang 050091 China Hebei General Hospital Shijiazhuang 050051 China The First Hospital of Shijiazhuang Shijiazhuang 050011 China 不详

Objective: To analyze the clinical effect of traditionaldog-days acupoint application and Magic Acupuncture Patch (Manji) in the prevention and treatment of chronic bronchitis (CB) in remission stage in the past five years, and explore the principle of action and effective stimulation, to provide the evidence for treating CB by acupoint application. Methods: A retrospective study was conducted on 405 patients with CB who met the inclusion criteria. All patients were treated with dog-days acupoint application or Magic Acupuncture Patch between 2013 and 2017. The clinical data of 405 patients were statistically analyzed to compare the prevention and treatment effects of dog-days acupoint application and Magic Acupuncture Patch, and different degrees of stimulation of dog-days acupoint application. Results: Among the dog-days acupoint application groups, the total effective rate was 63.6% in the light stimulation group, 93.1% in the moderate stimulation group, and 94.8% in the strong stimulation group. The differences in the total effective rate between the light stimulation group and the moderate stimulation group, as well as the strong stimulation group, were statistically significant (both P0.05). The total effective rate was 83.9% in the dog-days acupoint application group, versus 45.4% in the Magic Acupuncture Patch group, and there was a statistically significant difference between the two groups (P<0.05). Conclusion: The efficacy of dog-days acupoint application in the prevention and treatment of CB is better than that of Magic Acupuncture Patch;the degree of stimulation is the basis for the effect of dog-days acupoint application on prevention and treatment of CB, and the moderate and strong stimulations are more appropriate.

关键词： Acupoint Therapy Blistering Therapy Acupoint Sticking Therapy Application Therapy Winter Diseases Summer Treatment Bronchitis, Chronic

Efficacy observation of long-retaining scalp acupuncture plus interactive training for upper-extremity dysfunction after cerebral stroke

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Journal of Acupuncture and Tuina Science 2021年第1期19卷 43-48页

作者： Qi Cong-hui cui lin-hua Yuan Ye Tian Yao Yang Jie Xing Xiao Zhang Sha Chen Yuan-wu Department of Acupuncture Hebei General HospitalShijiazhuang 050051China Department of Rehabilitation Hebei General HospitalShijiazhuang 050051China Department of Rehabilitation Hebei Yiling HospitalShijiazhuang 050000China

Objective:To observe the efficacy of long-retaining scalp acupuncture plus interactive training in improving upper-extremity dysfunction in cerebral stroke ***:Ninety-five patients with upper-extremity dysfunction after cerebral stroke were randomized into two groups,with 48 cases in the treatment group and 47 cases in the control *** internal medicine treatment was offered to both *** both groups,Anterior Oblique line of Vertex-temporal(MS 6,the middle 2/5)and Posterior Oblique line of Vertex-temporal(MS 7,the middle 2/5)were selected from the same side of the brain lesion(the side apposing to the hemiplegic limb)for scalp acupuncture *** the treatment group,the scalp acupuncture needles were retained for 7 h,in combination with interactive training,while the needles were also retained for 7 h in the control group but without interactive *** to treatment and at 2-week and 4-week treatment,the two groups were scored using the functional test for the hemiplegic upper extremity-Hong Kong(FTHUE-HK)and simplified Fugl-Meyer assessment-upper extremity(FMA-UE).Results:The total effective rate was 97.9%in the treatment group,higher than 74.5%in the control group(P0.05),while the between

关键词： Acupuncture Therapy Scalp Acupuncture Scalp Stimulation Areas Needle Retaining Stroke Poststroke Syndrome Upper Extremity Shoulder Pain

Strategies for achieving fast-charge and high-voltage polymer-based solid-state lithium metal batteries

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Science China Chemistry 2025年

作者： Zitian lin Sucheng Liu Ce cui Wuhua Liu Yufeng Su Huiyu Song Li Du Jianqiang Hu Zhiming cui Guangdong Provincial Key Laboratory of Fuel Cell Technology School of Chemistry and Chemical Engineering South China University of Technology

Solid-state polymer electrolytes hold the potential for market application due to the combination of advantageous properties,such as flexibility,ease of processing and low ***,the sluggish ion transport and poor high-voltage stability pose significant challenges for the practical application of polymer-based solid-state lithium metal batteries (SSLMBs).Therefore,the design and development of polymer-based SSLMBs toward fast-charge and high-voltage is of great significance in high-energydensity ***,this review deeply analyzes the mechanism of ion transport and anti-oxidation of polymer-based solidstate ***,we also systematically and comprehensively summarize the factors that affect ionic conductivity and the electrochemical ***,we outline the solution strategies for simultaneously enhancing both ionic conductivity and high-voltage ***,we discuss the main challenges and the future prospects of polymer-based SSLMBs for further *** is hoped that this review can provide both advances and fundamentals to the research community and pave the way for the development of SSLMBs

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Infiltration by monocytes of the central nervous system and its role in multiple sclerosis: reflections on therapeutic strategies

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Neural Regeneration Research 2025年第3期20卷 779-793页

作者： Guangyong Zhang Qing Yao Chubing Long Pengcheng Yi Jiali Song Luojia Wu Wei Wan Xiuqin Rao Yue lin Gen Wei Jun Ying Fuzhou hua Department of Anesthesiology the Second Affiliated Hospital of Nanchang UniversityNanchangJiangxi ProvinceChina Key Laboratory of Anesthesiology of Jiangxi Province NanchangJiangxi ProvinceChina

Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in the neuroinflammatory process. Monocytes play a significant role in neuroinflammation, and managing neuroinflammation by manipulating peripheral monocytes stands out as an effective strategy for the treatment of multiple sclerosis, leading to improved patient outcomes. This review outlines the steps involved in the entry of myeloid monocytes into the central nervous system that are targets for effective intervention: the activation of bone marrow hematopoiesis, migration of monocytes in the blood, and penetration of the blood–brain barrier by monocytes. Finally, we summarize the different monocyte subpopulations and their effects on the central nervous system based on phenotypic differences. As activated microglia resemble monocyte-derived macrophages, it is important to accurately identify the role of monocyte-derived macrophages in disease. Depending on the roles played by monocyte-derived macrophages at different stages of the disease, several of these processes can be interrupted to limit neuroinflammation and improve patient prognosis. Here, we discuss possible strategies to target monocytes in neurological diseases, focusing on three key aspects of monocyte infiltration into the central nervous system, to provide new ideas for the treatment of neurodegenerative diseases.

关键词： blood–brain barrier macrophages monocytes multiple sclerosis neuroinflammation review therapy

Observation on instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method for primary headache

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Journal of Acupuncture and Tuina Science 2017年第5期15卷 366-370页

作者：邢潇张莉芳崔林华刘卫华王艳君洪珏 Acupuncture Department of Hebei General Hospital Rehabilitation and Physiotherapy Center First Hospital of Shijiazhuang City Traditional Chinese Medicine Department Laishui County Hospital Acupuncture Department Affiliated Hospital of Hebei University of Chinese Medicine

Objective： To observe the instant analgesic effect of Governor Vessel-regulating and collateral-unblocking acupuncture method in treating primary headache and to inherit and carry forward the academic achievements of Gao＇s acupuncture school in Yanzhao （Hebei Province） area. Methods： Eighty eligible primary headache patients were randomized into an observation group and a control group following their visiting sequence, 40 patients in each group. The observation group was intervened by Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture, and the control group was intervened by ordinary acupuncture method. The visual analogue scale （VAS） was used to evaluate the headache intensity before and after the first treatment session in the two groups, to compare the instant analgesic effect of the two acupuncture methods. Results： After the first treatment session, the VAS scores dropped significantly in both groups （both P〈0.05）. The change of VAS score after the initial treatment in the observation group was significantly different from that in the control group （P〈0.05）. The percentage of patients with headache completely vanished instantly after the first treatment was markedly higher in the observation group than that in the control group （P〈0.05）. Conclusion： The two acupuncture methods both can produce a significant instant analgesic effect in treating primary headache, while Yanzhao Gao＇s Governor Vessel-regulating and collateral-unblocking acupuncture method is superior to ordinary acupuncture method.

关键词： Acupuncture Therapy Acupuncture Analgesia Headache Governor Vessel Gao's Acupuncture Academic School in Yanzhao Area Visual Analogue Scale

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氧漂稳定剂的稳定性理论及其制备

潍坊学院学报 2005年第6期5卷 101-104页

作者：孙晓日林翠花潍坊学院山东潍坊261061

本文详细讨论了双氧水漂白原理、氧漂稳定剂稳定机理及制备方法,指出了研究高效氧漂稳定剂的方向。

关键词：双氧水氧漂稳定剂漂白稳定性理论制备方法