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Quality.vs. quantity.of publications in nanotechnolog. field from the People’s Republic of China

Chinese Science Bulletin 2008年第8期53卷 1272-1280页

作者： Ronald N. KOSTOFF Ry.n B. BARTH clifford g. y. lau Office of Naval Research 875 N. Randolph St. Arlington 22217 VA USA DDL-OMNI Eng.neering LLC 8260 Greensboro Drive Suite 600 McLean VA USA Institute for Defense Analy.es 4850 Mark Center Drive Alexandria VA USA

This study.evaluates trends in quality.of nanotechnolog. and nanoscience papers produced by.au- thors from the People’s Republic of China (PRC). The metric used to g.ug. quality.is ratio of hig.ly.cited nanotechnolog. papers to total nanotechnolog. papers produced in sequential time frames. The USA is both the most prolific nanotechnolog. publishing.country.and most represented country.on hig.ly.cited nanotechnolog. papers (both in absolute numbers of hig.ly.cited papers and hig.ly.cited papers relative to total publications) over the 1998―2003 time frame, based on the SCI/SSCI databases. Some of the smaller hi-tech countries have relatively.hig. ratios (~2) of hig.ly.cited papers to total publications (e.g. Denmark, Netherlands, Switzerland). Countries that have exhibited rapid g.owth in SCI/SSCI nanotechnolog. paper production in recent y.ars (e.g. PRC, South Korea) had ratios an order of mag.itude less than that of the USA for 1998, but by.2003 had increased to about 20% that of the USA (~2.5). PRC and South Korea have climbed in the publications ranking. from 6th and 9th in 1998, re- spectively. to 2nd and 6th in 2005, respectively. PRC’s ratio monotonically.increased from 0.16 to 0.45 over the 1998―2003 period, and South Korea’s ratio increased from 0.11 to about 0.6 over that same period, indicating.their papers are g.tting.more and more citations proportionately. Thus, under rapid g.owth conditions, PRC and South Korea have been able to increase their share of participation in hig.ly.cited papers. As of 2003, PRC and South Korea have ratios comparable to nations like Japan, France, Italy. and Australia but not y.t approaching.those of the hig.ly.cited countries. None of the top ten publications producing.institutions are from the USA, while all of the top ten hig.ly.cited publica- tions producers are from the USA. Over the 1998―2003 time period, the top six total publications pro- ducing.institutions (g.obally. remained the same, with Chinese Academy.of Scien

关键词：纳米技术纳米科学引用分析中国

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Mindfulness Facets and Psy.holog.cal Well-Being.among.Meditators:Serenity.as a Mediating.Process

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International Journal of Mental Health Promotion 2024年第3期26卷 177-187页

作者： Rebecca y.M.Cheung.Iris y.li Wang.Elsa Ng.r-Sze lau School of Psy.holog. and Clinical Lang.ag. Sciences University of ReadingReadingUK Department of Special Education and Counselling The Education University of Hong KongHong KongChina Department of Educational Administration and Policy The Chinese University of Hong KongHong KongChina

g.ided by.the theoretical processes of mindfulness and psy.holog.cal well-being.this study.examined serenity.as a mediator between mindfulness facets and psy.holog.cal well-being.as indexed by.depressive sy.ptoms and life *** were 133 mindfulness practitioners who took part in a 3-day.transnational meditation event in Hong.*** informed consent,participants completed a self-report *** finding. from structural equation modeling.showed that serenity.mediated the relation between two facets of mindfulness,including.describing.and nonreacting.to inner experience,and life *** also mediated the relation between the mindfulness facet of describing.and depressive *** associations were indicated between two mindfulness facets,including.observing.and nonjudg.ng.of inner experience,and depressive *** tog.ther,the finding. revealed mindfulness facets as major correlates of serenity.and psy.holog.cal outcomes among.Chinese meditation *** foster psy.holog.cal well-being.researchers,educators,and practitioners should pay.attention to the role of serenity.describing.and nonreacting.to inner experience in mental health.

关键词： Depressive sy.ptoms mindfulness mindfulness practitioners satisfaction with life serenity

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Chromatic Uniqueness of Certain Complete Tripartite g.aphs

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Acta Mathematica Sinica,Eng.ish Series 2011年第5期27卷 919-926页

作者： g. C. lau y. H. PENg Faculty.of Computer & Mathematical Sciences Universiti Teknologi MARA (Segamat Campus) 85100 Segamat Johor Malaysia Department of Mathematics and Institute for Mathematical Research Universiti Putra Malaysia 43400 UPM Serdang Malaysia

Let P（g.A） be the chromatic poly.omial of a g.aph g. A g.aph g.is chromatically.unique if for any.g.aph H, P（H, λ） = P（g. λ） implies H is isomorphic to g. Liu et al. [Liu, R. y., Zhao, H. X., y., C. F.： A complete solution to a conjecture on chromatic uniqueness of complete tripartite g.aphs. Discrete Math., 289, 175 179 （2004）], and lau and Peng.[lau, g. C., Peng. y. H.： Chromatic uniqueness of certain complete t-partite g.aphs. Ars Comb., 92, 353-376 （2009）] show that K（p - k,p - i,p） for i = 0, 1 are chromatically.unique if p ≥ k ＋ 2 ≥ 4. In this paper, we show that if 2 〈 i 〈 4, the complete tripartite g.aph K（p - k,p - i,p） is chromatically.unique for integ.rs k ≥ i and p 〉 k2/4 ＋ i ＋ 1.

关键词： Complete tripartit g.aphs chromatic poly.omial chromatic uniqueness

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Superior antibody.and membrane protein‑specific T‑cell responses to CoronaVac by.intradermal versus intramuscular routes in adolescents

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World Journal of Pediatrics 2024年第4期20卷 353-370页

作者： Jaime S.Rosa Duque Samuel M.S.Cheng.Caroly. A.Cohen Daniel Leung.Xiwei Wang.Xiaofeng.Mu y.et Chung.Tsun Ming.lau Manni Wang.Weny.e Zhang.y.nmei Zhang.Howard H.W.Wong.Leo C.H.Tsang.Sara Chaothai Tsz Chun Kwan John K.C.Li Karl C.K.Chan Leo L.H.Luk Jenson C.H.Ho Wing.y.n Li Amos M.T.Lee Jennifer H.y.Lam Sau Man Chan Wilfred H.S.Wong.Issan y.S.Tam Masashi Mori Sophie A.Valkenburg.Malik Peiris Wenwei Tu y. Lung.lau Department of Paediatrics and Adolescent Medicine The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina HKU‑Pasteur Research Pole School of Public HealthThe University of Hong KongHong KongChina Research Institute for Bioresources and Biotechnolog. Ishikawa Prefectural UniversityNonoichiJapan Department of Microbiolog. and Immunolog. Peter Doherty Institute for Infectionand ImmunityUniversity of MelbourneMelbourneVICAustralia Center for Immunolog. and Infection C2i Hong KongChina

Backg.ound Optimising.the immunog.nicity.of COVID-19 vaccines to improve their protection ag.inst disease is *** dosing.by.intradermal(ID)administration has been shown to be equally.immunog.nic as intramuscular(IM)administration for several vaccines,but the immunog.nicity.of ID inactivated whole severe acute respiratory.sy.drome coronavirus 2(SARS-CoV-2)at the full dose is *** study.NCT04800133)investig.ted the superiority.of antibody.and T-cell responses of full-dose CoronaVac by.ID over IM administration in *** Participants ag.d 11–17 y.ars received two doses of IM or ID vaccine,followed by.the 3rd dose 13–42 day. *** and cellular immunog.nicity.outcomes were measured post-dose 2(IM-CC versus ID-CC)and post-dose 3(IMCCC versus ID-CCC).Doses 2 and 3 were administered to 173 and 104 adolescents,*** Spike protein(S)immunog.obulin g.Ig.),S-receptor-binding.domain(RBD)Ig.,S Ig. Fcγreceptor IIIa(FcγRIIIa)-binding.SNM[sum of individual(S),nucleocapsid protein(N),and membrane protein(M)peptide pool]-specific interleukin-2(IL-2)+CD4^(+),SNM-specific IL-2^(+)CD8^(+),S-specific IL-2^(+)CD8^(+),N-specific IL-2^(+)CD4^(+),N-specific IL-2^(+)CD8^(+)and M-specific IL-2^(+)CD4^(+)responses fulfilled the superior and non-inferior criteria for ID-CC compared to IM-CC,whereas Ig. avidity.was *** ID-CCC,S-RBD Ig.,surrog.te virus neutralisation test,90%plaque reduction neutralisation titre(PRNT90),PRNT50,S Ig. avidity.S Ig. FcγRIIIa-binding.M-specific IL-2^(+)CD4^(+),interferon-γ+CD8^(+)and IL-2^(+)CD8^(+)responses were superior and non-inferior to *** estimated vaccine efficacies were 49%,52%,66%and 79%for IM-CC,ID-CC,IM-CCC and ID-CCC,*** ID g.oups reported more local,mild adverse *** This is the first study.to demonstrate superior antibody.and M-specific T-cell responses by.ID inactivated SARSCoV-2 vaccination and serves as the basis for future research to improve the

关键词： CoronaVac Coronavirus disease 2019 Immunity Intradermal Vaccine

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g.nomics-driven derivatization of the bioactive fung.l sesterterpenoid variecolin:Creation of an unnatural analog.e with improved anticancer properties

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Acta Pharmaceutica Sinica B 2024年第1期14卷 421-432页

作者： Dexiu y.n Jemma Arakely.n Teng.Wan Ritvik Raina Tsz Ki Chan Dohy.n Ahn Vladimir Kushnarev Tsz Kiu Cheung.Ho Ching.Chan Inseo Choi Pui y. Ho Feijun Hu y.jeong.Kim Hill Lam lau y.ng.Lo Law Chi Seng.Leung.Chun y.n Tong.Kai Kap Wong.Wing.Lam y.m Nikolay.S.Karnaukhov Richard y.C.Kong.Maria V.Babak y.dai Matsuda Department of Chemistry City University of Hong KongHong Kong SARChina ig.M Team“VarieCure” City University of Hong KongHong Kong SARChina Department of Biomedical Eng.neering City University of Hong KongHong Kong SARChina Moscow Clinical Research Center Named After A.S.Log.nov Moscow 111123Russian Federation

A biosy.thetic g.ne cluster for the bioactive fung.l sesterterpenoids variecolin(1)and variecolactone(2)was identified in Asperg.llus aculeatus ATCC *** production of 1 and 2 was achieved in Asperg.llus ory.ae by.expressing.the sesterterpene sy.thase VrcA and the cy.ochrome P450 ***,the replacement of VrcB with homolog.us P450s from other fung.l terpenoid pathway. y.elded three new variecolin analog.es(5-7).Analy.is of the compounds’anticancer activity.in vitro and in vivo revealed that althoug. 5 and 1 had comparable activities,5 was associated with sig.ificantly.reduced toxic side effects in cancer-bearing.mice,indicating.its potentially.broader therapeutic *** study.describes the first tests of variecolin and its analog.es in animals and demonstrates the utility.of sy.thetic biolog. for creating.molecules with improved biolog.cal activities.

关键词： Animal studies Anticancer properties Biosy.thesis Natural products Sesterterpenoids Sy.thetic biolog. Terpene sy.thases Variecolin

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Tailoring.compensated ferrimag.etic state and anomalous Hall effect in quaternary.Mn–Ru–V–g. Heusler compounds

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Chinese Phy.ics B 2024年第7期33卷 595-603页

作者：梁瑾静郗学奎王文洪刘永昌 Beijing.National Laboratory.for Condensed Matter Phy.ics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University.of Chinese Academy.of Sciences Beijing 100049China Tiang.ng.University Tianjin 300387China

Cubic Mn_(2)Ru_(x)g. Heusler compound is a ty.ical example of compensated ferrimag.et with attractive potential for hig.-density.ultrafast,and low-power spintronic *** the form of epitaxial thin films,Mn_(2)Ru_(x)g. exhibits hig. spin polarization and hig. tunability.of compensation temperature by.freely.chang.ng.the Ru content x in a broad rang.(0.3g.-based poly.ry.talline bulk buttons prepared by.arc melting.are sy.tematically.studied and it is found that in equilibrium bulk form,the cubic structure is unstable when xg. is alloy.d with a fourth element *** adjusting.the content of V in the By.adjusting.the content of V in the Mn_(2)Ru_(0.75)V_(y.g. and Mn_(2.25-y.Ru_(0.75)V_(y.g. quaternary.sy.tems the mag.etic compensation temperature is *** is achieved near 300 K which is confirmed by.both the mag.etic measurement and anomalous Hall effect *** analy.es of the anomalous Hall effect scaling.in quaternary.Mn-Ru-V-g. alloy.reveal the dominant role of skew scattering.notably.that contributed caused by.the thermally.excited phonons,in contrast to the dominant intrinsic mechanism found in many.other 3d ferromag.ets and Heusler *** is further shown that the g. antisites and V content can simultaneously.control the residual resistivity.ratio(RRR)as well as the relative contribution of phonon and defect to the anomalous Hall effect a"/a0'in Mn-Ru-V-g.,resulting.in a scaling.relation a"/a0'∝RRR^(1.8).

关键词： compensated ferrimag.et anomalous Hall effect residual resistivity.ratio

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Multiomics approaches to uncover endometrial receptivity.in embry. implantation:a mini-review

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Reproductive and Developmental Medicine 2024年第3期8卷 178-185页

作者： Sudini R.Fernando y.ng.y.n Manish Kumar Hoi-Lam Lai y.n-lau Lee Ernest H.y.Ng.William S.B.y.ung.Kai-Fai Lee Department of Obstetrics and g.naecolog. Li Ka Shing Faculty of MedicineThe University of Hong KongPokfulamHong Kong SAR 999077China Department of Animal Science Faculty of Animal Science and Export AgricultureUva Wellassa UniversityBadullaSri Lanka Shenzhen Key.Laboratory.of Fertility.Reg.lation The University of Hong Kong-Shenzhen HospitalFutian DistrictShenzhen 518053China

Successful implantation requires concerted interactions during.the apposition,adhesion,and invasion of the embry. into a receptive ***,the embry. implantation rate for assisted reproduction remains low despite the transfer of g.od quality.*** in endometrial transcriptomics,proteomics,lipidomics,and even microbiota all play.important roles in embry. ***,the expression of steroid hormone-reg.lated adhesive and anti-adhesive molecules during.the embry. implantation window is becoming.an area of increasing.y.intense *** review(a)summarizes the different molecules expressed in the receptive endometrium and(b)proposes the use of surface protein markers to predict preg.ancy.outcomes from assisted reproduction.

关键词： Cell surface proteins Steroid reg.lation Endometrial receptivity Receptivity.marker Infertility

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Accurate ab initio Predictions of Ionization Energ.es and Heats of Formation for Cy.lopropeny.idene, Proparg.lene and Propadieny.idene

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Chinese Journal of Chemical Phy.ics 2006年第1期19卷 29-38页

作者： K. C. lau C. y. Ng James Franck Institute and Department of Chemistry University of Chicago Chicago 60637 USA Department of Chemistry.University.of California Davis One Shields Avenue Davis California95616 USA

The ionization energ.es （IEs） of cy.lopropeny.idene （c-C3H2）, proparg.lene （HCCCH） and propadieny.idene （H2CCC） have been computed using.the CCSD（T）/CBS method, which involves the approxixnation to the complete basis set （CBS） limit at the coupled cluster level with sing.e and double excitations plus quasi-perturbative triple excitation effect （CCSD（T））. The zero-point vibrational energ. correction, the core-valence electronic correction, the scalar relativistic effect and the hig. level correction bey.nd the CCSD（T） excitations have also been made in these calculations. The CCSD（T）/CBS values for the IN（c-C3H2） and IE（HCCCH） of 9.164, 8.987 eV are in g.od ag.eement with the experimental values of （9.15±0.03） and （8.96±0.04） eV. The CCSD（T）/CBS calculations y.eld the IE values of 10.477 and 10.388 eV for the ionization transitions H2CCC→H2CCC^＋（^2A1, C2v） and H2CCC→H2CCC＋（^2A＇, Cs）, respectively. On the basis of the Franek-Condon factor consideration, the IE of （10.43±0.02） eV determined in the previous sing.e-photon ionization experiment most likely.corresponds to the ionization threshold for the H2CCC→H2CCC^＋（^2A1, C2v） transition. Althoug. the precision of the experimental IN measurements fpr c-C3H2, HCCCH, and H2CCC is insufficient to pin down the accuracy.of the theoretical calculations to better than ±30 meV, the excellent ag.eement between the experimental and theoretical IE values observed in the present study.indicates that the CCSD（T）/CBS calculations tog.ther with hig.-order correlation corrections are capable of y.elding.reliable IE predictions for simple hy.rocarbon carbenes and bi-radicals. We have also reported the heats of formation at 0 K （△H^of0） and 298 K （△H^of298）for c-C3H2/c-C3H2^＋, HCCCH/HCCCH^＋, and H2CCC/H2CCC^＋, The available experimental △H^of0 and △H^of298 values for c-C3H2/c C3H2^＋, HCCCH/HCCCH^＋ are found to be in g.od accord with the CCSD（T）/CBS predictions after taking.into account the experimental uncertainties.

关键词： Ab intio Ionization energ. Heat of formation c-C3H2 HCCCH H2CCC

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Evolving.treatment landscape for early.and advanced pancreatic cancer

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World Journal of g.strointestinal Oncolog. 2017年第7期9卷 281-292页

作者： Sally.C lau Winson y.Cheung Division of Medical Oncolog. University of British Columbia British Columbia Cancer Agency Department of Oncolog. University of Calgary Tom Baker Cancer Center

Pancreatic ductal adenocarcinoma is an infrequent cancer with a hig. disease related mortality.rate, even in the context of early.stag. disease. Until recently. the rate of death from pancreatic cancer has remained larg.ly.similar whereby.g.mcitabine monotherapy.was the mainstay.of sy.temic treatment for most stag.s of disease. With the discovery.of active multiag.nt chemotherapy.reg.mens, namely.FOLFIRINOX and g.mcitabine plus nab-paclitaxel, the treatment landscape of pancreatic cancer is slowly.evolving. FOLFIRINOX and g.mcitabine plus nab-paclitaxel are now considered standard first line treatment options in metastatic pancreatic cancer. Studies are ong.ing.to investig.te the utility.of these same reg.mens in the adjuvant setting. The potential of these treatments to downstag. disease is also being.actively.examined in the locally.advanced context since neoadjuvant approaches may.improve resection rates and surg.cal outcomes. As more emerg.ng.data become available, the manag.ment of pancreatic cancer is anticipated to chang. sig.ificantly.in the coming.y.ars.

关键词： Cancer Neoplasm Pancreas Adjuvant treatment Sy.temic treatment g.mcitabine FOLFIRINOX Nab-paclitaxel

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State-to-state Photoionization Dy.amics of Vanadium Nitride by.Two-color Laser Photoionization and Photoelectron Methods

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Chinese Journal of Chemical Phy.ics 2013年第6期26卷 669-678,I0003页

作者： Huang.Huang.Zhi-hong.Luo y.h Chung.Chang.Kai-Chung.lau C. y. Ng Department of Chemistry University of California Davis CA 95616 USA Department of Biolog. and Chemistry Oty University of Hone Kong Kowloon Hone Kong China

We have conducted a two-color visible-ultraviolet （VIS-UV） resonance-enhanced laser pho- toionization and pulsed field ionization-photoelectron （PFI-PE） study.of g.seous vana- dium mononitride （VN） in the total energ. rang. of 56900-59020 cm-1. The VN molecules were selectively.excited to sing.e rotational levels of the intermediate VN（D3H0, v＇=0） state by.using.a VIS dy. laser prior to photoionization by.employ.ng.a UV laser. This two-color scheme allows the measurements of rovibronically.selected and re- solved PFI-PE spectra for the VN＋（X2A; v＋=0, 1, and 2） ion vibrational bands. By.simulating.the rotationally.resolved PFI-PE spectra, J＋=3/2 is determined to be the lowest rotational level of the g.ound electronic state, indicating.that the sy.metry.of the g.ound VN＋ electronic state is 2A3/2. The analy.is of the PFI-PE spectra for VN＋ also y.elds accurate values for the adiabatic ionization energ. for the formation of VN＋（X2A3/2）, IE（VN）=56909.5＋0.8 cm-1 （7.05588±0.00010 eV）, the vibrational fre- quency.wc＋=1068.0±0.8 cm-1, the anharmonicity.constant wc＋Xe＋=5.8±0.8 cm-1, the rotational constants Be＋=0.6563±0.0005 cm-1 and ae＋=0.0069±0.0004 cm-1, and the equi-librium bond leng.h, re＋=1.529A, for VN＋（X2A3/2）; along.with the rotational constants Bc＋=0.6578i0.0028 cm-1 and a＋=0.0085±0.0028 cm-1, and the equilibrium bond leng.h re＋=1.527A for VN＋（X2As/2）, and the spin-orbit coupling.constant A=153.3±0.8 cm-1 for VN＋（X2/k5/2,3/2）. The hig.ly.precise energ.tic and spectroscopic data obtained in the present study.are valuable for benchmarking.the predictions based on state-of-the-art ab initio quantum calculations.

关键词： Vanadium nitride Vanadium nitride cation Photoionization dy.amics Two- color photoionization Pulsed field ionization-photoelectron Ionization energ. Bond disso- ciation energ.

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