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Strongly Gorenstein Flat Dimensions

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Journal of Mathematical Research and Exposition 2011年第6期31卷 977-988页

作者： chun xia ZHANG li Min WANG Department of Mathematics Northwest Normal University Gansu 730070 P. R. China

This article is concerned with the strongly Gorenstein flat dimensions of modules and *** show this dimension has nice properties when the ring is coherent,and extend the well-known Hilbert＇s syzygy theorem to the strongly Gorenstein flat dimensions of ***,we investigate the strongly Gorenstein flat dimensions of direct products of rings and（almost）excellent extensions of rings.

关键词： strongly Gorenstein flat module strongly Gorenstein flat dimension coherent ring direct product (almost)excellent extension

Chemical Vapor Deposition Growth of Large-Area Monolayer MoS_2 and Fabrication of Relevant Back-Gated Transistor

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Chinese Physics Letters 2019年第3期36卷 70-73页

作者： Jian-Ying Chen Lu liu chun-xia li Jing-Ping Xu School of Optical and Electronic Information Huazhong University of Science and Technology Shenzhen Institution of Information Technology

A closed two-temperature-zone chemical vapor deposition(CVD) furnace was used to grow monolayer molybdenum disulfide(MoS_2) by optimizing the temperature and thus the evaporation volume of the Mo precursor. The experimental results show that the Mo precursor temperature has a large effect on the size and shape transformation of the monolayer MoS_2, and at a lower temperature of 760°C, the shape starts to change from a triangle to a truncated triangle. A large-area triangular monolayer MoS_2 with a side length of 145 °m is achieved at 760°***, the as-grown monolayer MoS_2 is used to fabricate back-gated transistors by means of electron beam lithography to evaluate the electrical properties of MoS_2 thin films. The MoS_2 transistors with monolayer MoS_2 grown at 760°C exhibit a high on/off current ratio of 10~6, a mobility of 1.92 cm^2/Vs and a subthreshold swing of 194.6 mV/dec, demonstrating the feasible approach of CVD deposition of monolayer MoS_2 and the fabrication of transistors on it.

关键词： Chemical Large-Area Monolayer Fabrication

Improved interfacial properties of HfGdON gate dielectric Ge MOS capacitor by optimizing Gd content

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Chinese Physics B 2019年第12期28卷 331-337页

作者： lin Zhou Lu liu Yu-Heng Deng chun-xia li Jing-Ping Xu School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China Shenzhen Institute of Information Technology Shenzhen 518172China

High-quality dielectric/Ge interface and low gate leakage current are crucial issues for high-performance nanoscaled Ge-based complementary metal–oxide–semiconductor(CMOS) device. In this paper, the interfacial and electrical properties of high-k Hf Gd ON/La Ta ON stacked gate dielectric Ge metal–oxide–semiconductor(MOS) capacitors with different gadolinium(Gd) contents are investigated. Experimental results show that when the controlling Gd content is a suitable value(e.g., 13.16%), excellent device performances can be achieved: low interface-state density(6.93 × 10^11 cm^-2·e V-1), small flatband voltage(0.25 V), good capacitance–voltage behavior, small frequency dispersion, and low gate leakage current(2.29× 10^-6 A/cm^2 at Vg = Vfb + 1 V). These could be attributed to the repair of oxygen vacancies, the increase of conduction band offset, and the suppression of germanate and suboxide Ge Ox at/near the high k/Ge interface by doping suitable Gd into Hf ON.

关键词： Ge MOS devices HfGdON dielectric interface quality leakage current density

Effects of daily telephone-based re-education before taking medicine on Helicobacter pylori eradication: A prospective single-center study from China

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World Journal of Gastroenterology 2015年第39期21卷 11179-11184页

作者： chun-Hua Wang Sheng-Tao liao Jun Yang chun-xia li Ying-Ying Yang Ran Han Dong-Feng Chen chun-Hui Lan Department of Gastroenterology Daping Hospital the Third Military Medical University Cadet Brigade the Third Military Medical University Department of Gastroenterology Guizhou Aerospace Hospital

AIM: To investigate the effects of daily telephonebased re-education(TRE) before taking medicine for the eradication of Helicobacter pylori(H. pylori) on the compliance and the eradication rate in a Chinese patient *** : Aprospective, physician-blind e d, randomized, controlled clinical study was conducted. The patients were randomly assigned to receive TRE every day before taking medicine(TRE group) or no TRE(control group). The patients in the TRE group received regular instructions before taking medicine for the eradication of H. pylori during the entire courseof treatment through telephone calls. The patients in the control group received detailed instructions at the time of seeing a doctor for the guidance. The primary outcome was the H. pylori eradication rate after treatment. The secondary outcomes included the clinical remissions after treatment, adverse events, compliance, and patients' ***: A total of 140 patients were randomized, 70 to the TRE group and 70 to the control group. As the primary outcome, the H. pylori eradication rates in the TRE and control groups were 62.7% and 71.2% in per protocol analysis(P = 0.230), and 52.9% and 52.9% in intention-to-treat analysis(P = 0.567), respectively. As the secondary outcomes, there were no significant differences in the patients' satisfaction between the two groups(good, 79.7% vs 76.9%; fair, 13.6% vs 19.2%; poor, 6.7% vs 3.9%, for the TRE group and control group, respectively; P > 0.05 for all); the rates of adverse effects were 15.2% and 63.5% in the TRE and control groups, respectively(P liance rates in the TRE and control groups were 85.7% and 74.3%, respectively(P = 0.069).CONCLUSION: Daily TRE before taking medicine had no significant impact on the patients' compliance, satisfaction, or H. pylori eradication, but reduced the rate of adverse events.

关键词： Helicobacter pylori Eradication Telephone re-educa

Acetaminophen-induced acute pancreatitis: A case report and literature review

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World Journal of Clinical Cases 2018年第9期6卷 291-295页

作者： Ya-Hong He Lei Lu Yu-Fang Wang Jin-Song Huang Wei-Qin Zhu Yan Guo chun-xia li Hua-Ming li Department of Gastroenterology Hangzhou Third People’s Hospital Zhejiang Chinese Medical University Department of Gastroenterology Hangzhou First People’s Hospital Nanjing Medical University

Acute pancreatitis is rarely associated with drugs. Acetaminophen overdose is a well-known cause of hepatic toxicity, but drug-induced pancreatitis is rarely reported, especially after mild overdose. A 32-yearold woman presented with nausea and vomiting for 12 h, but no abdominal pain following an overdose of eight Tylenol tablets containing acetaminophen(325 mg acetaminophen per tablet). Laboratory results on admission showed abnormal amylase and lipase levels but completely normal liver function. Magnetic resonance cholangiopancreatography revealed mild swelling of the pancreas without fluid collection around the pancreas. The patient complained of severe abdominal pain five days after admission when attempting to drink water and liquids. Eight days after admission, fluid around the pancreas was observed by computed tomography. The patient was subsequently diagnosed with acetaminophen-induced acute pancreatitis after exclusion of common causes. Routine treatment for pancreatitis and N-acetylcysteine were administered to prevent disease progression. The patient was discharged in good condition.

关键词： Pancreatitis Cholangiopancreatography Acetaminophen Acute pancreatitis Drug-induced acute pancreatitis

Sevoflurane postconditioning protects isolated rat hearts against ischemia-reperfusion injury

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Chinese Medical Journal 2010年第10期123卷 1320-1328页

作者： YAO Yun-tai FANG Neng-xin SHI chun-xia li li-huan Department of Anesthesiology Fuwai Cardiovascular Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China

Background Studies suggested that anesthetics administered upon the early reperfusion or ＂anesthetic postconditioning＂ could protect post-ischemic hearts against myocardial ischemia reperfusion injury （MIRI）. However, the mechanism responsible for such protection was not well-elucidated. We investigated the cardioprotection induced by sevoflurane postconditioning （SpostC） in rat hearts in vitro, and the respective role of phosphatidylinositol-3-kinase （PI3K）, extracellular signal-regulated kinase 1 and 2 （ERK 1/2）, mitochondrial KATP channels （mitOKAme） and mitochondrial permeability transition pore （mPTP）, by selectively inhibiting PI3K, ERK 1/2, mitOKATP, with LY294002 （LY）, PD98059 （PD）, 5-hydroxydecanoate （5-HD） and by directly opening of mPTP with atractyloside （ATR）, respectively. Methods Isolated rat hearts were randomly assigned to one of the 12 groups （n=-15）： Time control （continuous perfusion）, ISCH （30 minutes of ischemia followed by 60 minutes of reperfusion alone）, SpostC （3% sevoflurane postconditioning was administered during the first 15 minutes of reperfusion after 30 minutes of ischemia）, ISCH＋LY, ISCH＋PD, ISCH＋ATR, ISCH＋5-HD and ISCH＋ dimethyl sulfoxide （DMSO） groups （LY, PD, ATR, 5-HD and DMSO （the vehicle） was administered respectively during the first 15 minutes of reperfusion following test ischemia）, SpostC＋LY, SpostC＋PD, SpostC＋ATR and SpostC＋5-HD groups （LY, PD, ATR and 5-HD was coadministered with 3% sevoflurane, respectively）. Hemodynamics was compared within and between groups. Infarction size was determined at the end of experiments using triphenyltetrazolium chloride （TTC） staining. Lactate dehydrogenase （LDH）, creatine kinase-MB （CK-MB） and cardiac troponin I （cTnl） released from necrotic myocardium, were compared among TC, ISCH and SpostC groups. To investigate the relationships between RISK and mPTP implicated in SpostC, NAD＋ content in myocardium, a marker of mPTP opening, was compared among some experimental groups （TC, ISCH, ISC

关键词： sevoflurane heart ischemia reperfusion

Effect of RNA Interference Hsp72 Gene Expression on Development of Mouse Preimplantation Embryos

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Agricultural Sciences in China 2009年第2期8卷 223-230页

作者： WANG Ming-zhi TIAN Wen-ru TIAN Zhong-jie QU Ping-ping GAO Shan-song ZHANG Zhi-hong ZHANG Qi-yao HOU chun-xia li Hui-hui College of Animal Science and Veterinary Medicine Qingdao Agricultural University Qingdao 266109 P.R.China

The method of RNAi was used to inhibit the expression of induced heat shock protein 70 （Hsp72） in the 4-cell stage mouse embryos and the embryo development competence was analyzed to identify the functions of Hsp72 on embryonic heat resistance. The results indicated that the inhibition rates of siRNA1 for Hsp72 mRNA and Hsp72 protein were 87.1 and 78.5%, respectively. The blastocysts development rates were 41, 86, and 84% for the siRNA1 group, the lipofectamineTM 2 000 exposed group, and the 37℃ group, respectively, and the hatched blastocysts development rates for the above three groups were 35, 72, and 68%, respectively. The data suggest that the siRNAI has a significant inhibiting effect on Hsp72 gene, and Hsp72 gene silence reduces the blastocysts development rate and hatched blastocysts rate after heat shock during the development of mouse preimplantation embryos.

关键词： RNA interference mouse blastocyst Hsp72 gene

Preparation of β-glucan Oligosaccharides derived from Curdlan

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Preparation of β-glucan Oligosaccharides derived from Curdl...

Association between Polymorphism of Interleukin-23 Receptor and Hashimoto＇s Thyroiditis in Chinese Han Population of Shandong

中国化学会第三届全国糖化学会议

作者： Yao li Quan-Cai li chun-xia li Key Laboratory of Marine Drugs Ministry of EducationSchool of Medicine and PharmacyOcean University of China Laboratory for Marine Drugs and Bioproducts of Pilot National Laboratory for Marine Science and Technology(Qingdao)

β-glucans are commonly used as functional food ingredients and recognized as potential immunological ***,the BG’s poor water solubility of β-glucans limits their *** order to gain different molecular weight water-soluble β-glucans,we used chemical and physical methods to degrade the β-glucan of Curdlan.P4 fine gel exclusion column was used to separate the degradation product of *** β-glucans oligosaccharides(BGOs)derived from Curdlan were analyzed by HIliC-ELSD method with a Click Xion column,and then separated by graphitized carbon black *** with a specific degree of polymerization(DP) from 2 to 10 were ***-MS has indicated the BGOs(DP 2-10)molecular weight:342,504,666,828,990,1152,1314,1476 and *** anomeric configuration and glycosidic linkage of BGOs were confirmed to be β-Glc-(1→3)-by 1 H and 13 C NMR *** this study we developed a HIliC-ELSD method for the compositional analysis of BGOs and obtained BGOs with specific *** work could potentially provide a basis for further research on the structure-activity relationship of series oligosaccharides(DP2-9) from Curdlan.

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Chinese Medical Journal 2015年第15期128卷 2050-2053页

作者： Zhi-Hua li Jie Han Yu-Fei Wang Jun Dai Hui Zhang chun-xia li Qun Ma Academy of Basic Medicine Jining Medical University Jining Shandong 272067 China Department of Surgery The Affiliated Hospital of Jining Medical University First People's Hospital of Jining Jining Shandong 272011 China

Objective：The interleukin-23 receptor （IL-23R） has been shown to be associated with autoimmune diseases in many different *** study aimed to investigate the association between IL-23R gene polymorphism and susceptibility to Hashimoto＇s thyroiditis （HT） in Chinese Han population of ***：A case-control cohort study was performed in 145 HT patients from First People＇s Hospital of Jining between February 2010 to October 2013 and 150 healthy *** single nucleotide polymorphisms located in the promoter region ofIL-23R gene （rs 17375018 and rs7517847） were examined by polymerase chain reaction-restriction fragment length polymorphism ***-Weinberg equilibrium was performed using the Chi-square *** frequencies were estimated by direct counting,and allele and genotype frequencies between patients and controls were analyzed by the Chi-square ***：The rs 17375018 GG genotype and the G allele were significantly increased in HT patients compared with healthy controls （P =0.034 and P =0.013,respectively）.No association was identified between HT patients and healthy controls in ***：The study demonstrated that polymorphism of IL-23R gene rs17375018 is highly associated with HT in Chinese Han population of Shandong,suggesting that IL-23R gene polymorphism （rs 17375018 G） may play a critical role in susceptibility to HT.

关键词： Genotype Hashimoto's Thyroiditis Interleukin-23 Receptor Polymorphism