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干热养护对活性粉末混凝土力学及收缩影响研究（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2018年第12期19卷 926-938页

作者： Jin-tao LIU Yang YANG chun-ping gu He-dong LI College of Architecture and Civil Engineering Zhejiang University of Technology School of Civil Engineering and Architecture Zhejiang Sci-Tech University

目的:高温干热养护工艺对活性粉末混凝土的力学强度及收缩性能有重要影响。本文针对不同的高温养护温度和时间分析活性粉末混凝土材料的抗压强度、抗折强度、收缩和微观结构,探索高温干热养护环境提升活性粉末混凝土材料力学性能的机理... 详细信息

目的:高温干热养护工艺对活性粉末混凝土的力学强度及收缩性能有重要影响。本文针对不同的高温养护温度和时间分析活性粉末混凝土材料的抗压强度、抗折强度、收缩和微观结构,探索高温干热养护环境提升活性粉末混凝土材料力学性能的机理,并讨论外部环境湿度对材料收缩变形的影响。创新点:1.通过调整不同养护工艺参数,大幅度提升活性粉末混凝土的早期强度;2.建立试验模型,成功模拟适应性冲压工艺过程。方法:1.通过实验分析,研究不同养护温度和养护时间对活性粉末混凝土力学强度的影响(表4);2.通过设计不同的养护湿度(50%和90%),构建后期养护环境与材料干燥收缩之间的关系,得到适应性的后期养护参数(表5);3.通过与已有研究的分析对比,提出适用于工程实际的高温干热养护工艺参数,并得出后期高湿度养护降低活性粉末混凝土收缩的微观机理(图7)。结论:1.通过调整高温养护的温度和养护时间可以对活性粉末混凝土的强度产生影响。2.试件在经历高温养护后再进行高湿度养护可以有效降低材料的后期干燥收缩。3.材料界面过渡区在高温养护条件下变得更加密实;在高温环境下生成托勃莫来石或硬硅钙石是材料获得较高强度的主要原因。

关键词：活性粉末混凝土高温养护力学性能收缩

Traditional Chinese medicine as monotherapy or combined with oseltamivir in the treatment of H1N1 influenza:a systematic review and meta-analysis

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TMR Modern Herbal Medicine 2022年第3期5卷 1-12页

作者： chun-ping gu Dong-Wei Ye Xin Mao Shu-Wen Liu Clinical Pharmacy Center Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China guangdong Provincial Key Laboratory of New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China

Objective This study aimed to assess the efficacy and safety of traditional Chinese medicine,alone or in combination with oseltamivir,in patients with H1N1 *** In the present study,we searched the Cochrane Central Register of Controlled Trials,PUBMED,EMBASE,Chinese Biomedical Literature Database,China Science and Technology Journal Database,China National Knowledge Infrastructure Database,and WanFang Data for studies published in or before February 8,*** were extracted and checked by two *** Manager 5.4 and STATA statistical software 16.0 were used for the data *** We identified 22 individual studies reporting data from 2292 individuals with H1N1 *** with oseltamivir,the fever clearance duration[MD=-3.99,95%CI(-6.89,-1.09)]and sore throat relief time[MD=-5.39,95%CI(-10.19,-0.59)]in the intervention group of traditional Chinese medicine monotherapy or combined with oseltamivir were *** was the primary component of *** subgroup analyses indicated that Maxingshigan shortened fever clearance time[MD=-3.23,95%CI(-5.60,-0.85)],and also had certain advantages in relieving sore throat[RR=-4.55,95%CI(-10.04,0.95)].However,as for the effective rate,fever duration,cough disappearance time,hospital length of stay,clinical symptoms time as well as viral shedding duration,there were no significant differences between the two ***,no serious adverse effects were reported in the included *** Although we couldn’t get a definitive conclusion due to the small sample sizes and high risk of bias in the included studies,most traditional Chinese medicine showed similar effects to oseltamivir in treating H1N1 *** were showed to have a statistically significant shorter time of fever clearance and sore throat remission when they were used alone or in combination with oseltamivir and were well-tolerated treatment,such as Maxingshigan.

关键词： traditional Chinese medicine maxingshigan oseltamivir H1N1 influenza meta-analysis

Synthesis and cytotoxicities of novel 7-methoxy-3-arylflavone-8-acetic acids

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Synthesis and cytotoxicities of novel 7-methoxy-3-arylflavon...

Ultrahigh performance concrete–properties, applications and perspectives

第八届全国化学生物学学术会议

作者： Yan-Hong Deng chun-ping gu guang-Hua Yan Le Yu Shu-Wen Liu Zhong-Zhen Zhou Wen-Hua Chen School of Pharmaceutical Sciences Southern Medical University

Thirteen new analogues of flavone-8-acetic acid(FAA),that is, 7-methoxy-3-arylflavone-8-acetic acids 10a-m were synthesized and fully characterized on the basis of MS(ESI and HR),NMR(H and C) and elemental analysis *** direct in vitro cytotoxicities against human colon adenocarcinoma HT-29 and lung adenocarcinoma A549 tumor cell lines were evaluated using MTT methods,whereas their indirect cytotoxicities against A549 cells were measured by

关键词： Flavone-8-acetic acid synthesis direct cytotoxicity indrect cytotoxicity

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Science China(Technological Sciences) 2015年第4期58卷 587-599页

作者： gu chun ping YE guang SUN Wei School of Materials Science & Engineering Southeast University Microlab Faculty of Civil Engineering and Geosciences Delft University of Technology Jiangsu Key Laboratory of Construction Materials Collaborative Innovation Center for Advanced Civil Engineering Materials

Over the last twenty years,remarkable advances have taken place in the research and application of ultra-high performance concrete(UHPC),which exhibits outstanding mechanical properties and excellent *** has shown great potential for the next generation infrastructure construction from the sustainability point of *** paper will give an overview on UHPC,with particular focus on the properties,applications and *** several decades of development,several types of commercial UHPC materials are available in the market,and the properties of UHPC have been characterized by numerous experimental and field *** speaking,the performance(*** properties and durability)of UHPC is much better than normal concrete(NC)and high performance concrete(HPC).Therefore,the uses of UHPC are growing all over the world,in both fields of new construction and ***,it is still a special material and technology,which is not worldwide *** some application prospects of UHPC are briefly introduced in the paper,and the efforts,which have to be made to turn UHPC into a widespread‘regular’technology,are *** paper aims to help designers,engineers,architects and infrastructure owners to know the capacities of UHPC and thus to increase the applications of this material.

关键词： UHPC characteristics durability applications perspectives

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-Hui Wei Shu-Hui Fan Li Chen Jie Wang Xiao-Qian Yang chun-Hao Yang Shi-Jun He Jian-ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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基于刻蚀处理的池沸腾传热性能实验研究

原子与分子物理学报 2025年第3期42卷 180-188页

作者：王菊萍匡纯纯刘妮上海理工大学制冷技术研究所上海200093

为探究刻蚀处理铜板表面对池沸腾传热性能的改善效果,搭建了可视化实验平台,制备不同刻蚀浓度和刻蚀时间处理的表面,采用去离子水为工质,进行饱和池沸腾实验.结果表明,氨水刻蚀浓度越大,表面的换热性能越强,氨水刻蚀时间越长,表面换热... 详细信息

为探究刻蚀处理铜板表面对池沸腾传热性能的改善效果,搭建了可视化实验平台,制备不同刻蚀浓度和刻蚀时间处理的表面,采用去离子水为工质,进行饱和池沸腾实验.结果表明,氨水刻蚀浓度越大,表面的换热性能越强,氨水刻蚀时间越长,表面换热性能越强.热流密度为43.2 W/cm^(2)时,0.05 mol/L氨水刻蚀4 h表面、0.05 mol/L氨水刻蚀5 h表面、0.05 mol/L氨水刻蚀8 h表面、0.03 mol/L氨水刻蚀4 h表面、0.05 mol/L氨水刻蚀4 h表面和0.10 mol/L氨水刻蚀4 h表面上的换热系数分别提高了46%、92%、105%、36%、45%、78%.此外,对其表面进行表征,结果说明了其优异的沸腾性能.刻蚀处理增强了表面粗糙度,有效面积,从而促进液体的补充,能够在较小的过热度下达到更高的临界热流密度.可视化研究结果表明,刻蚀表面具有更多的成核位点,更小的气泡离开直径和离开频率.这些结果显示出刻蚀表面强化池沸腾换热的潜力.

关键词：池沸腾刻蚀传热性能气泡动力学微纳结构表面

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高品质学校的内涵结构、建设困境与突破路径

教学与管理 2025年第1期 19-23页

作者：邓纯臻隆平陈书忠重庆师范大学生命科学学院重庆401331 四川省攀枝花市第七高级中学校四川攀枝花617005 重庆市育才中学校重庆400050

高品质学校的创建既是区域教育高质量发展的基本组成,也是助推教育强国、人才强国建设的实践基础。综合来看,学校内部维度的高品质是一种过程取向以及主观层面的高品质,外部维度的高品质是一种结果取向以及客观层面的高品质,高品质学校... 详细信息

高品质学校的创建既是区域教育高质量发展的基本组成,也是助推教育强国、人才强国建设的实践基础。综合来看,学校内部维度的高品质是一种过程取向以及主观层面的高品质,外部维度的高品质是一种结果取向以及客观层面的高品质,高品质学校包括学生、教师、管理者以及课程、课堂、课题六个核心的动力要素。当前,高品质学校的建设依然在前沿理论、本地生源、教育资源以及师资队伍等方面存在一些阻碍,对此,建议从学校文化、优质资源、课程体系、师资队伍、管评系统等五个维度探寻突破路径,以期找到高品质学校的创新之路、高品质之路。

关键词：教育高质量发展高品质学校中小学管理学校治理

Heterogeneity of immune control in chronic hepatitis B virus infection:Clinical implications on immunity with interferon-αtreatment and retreatment

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World Journal of Gastroenterology 2022年第40期28卷 5784-5800页

作者： guo-Qing Yin Ke-ping Chen Xiao-chun gu Center of Hepatology Zhong-Da HospitalSoutheast UniversityNanjing 210009Jiangsu ProvinceChina

Hepatitis B virus(HBV)infection is a global public health ***-α(IFN-α)treatment has been used to treat hepatitis B for over 20 years,but fewer than 5%of Asians receiving IFN-αtreatment achieve functional ***,IFN-αretreatment has been introduced to enhance antiviral *** recent years,immune-related studies have found that the complex interactions between immune cells and cytokines could modulate immune response networks,including both innate and adaptive immunity,triggering immune responses that control HBV ***,heterogeneity of the immune system to control HBV infection,particularly HBV-specific CD8^(+)T cell heterogeneity,has consequential effects on T cell-based immunotherapy for treating HBV ***,the host’s genetic variants,negative-feedback regulators and HBV components affecting the immune system's ability to control *** this study,we reviewed the literature on potential immune mechanisms affecting the immune control of HBV and the clinical effects of IFN-αtreatment and retreatment.

关键词： Hepatitis B virus Chronic Functional cure Heterogeneity Immunity Immune control Interferon-α Retreatment

Kinetics of stripping of gold loaded in DBC organic phase by sodium sulfite

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Rare Metals 2006年第1期25卷 1-6页

作者： ZHU ping gu guobang College of Envirotunent Science and Engineering Shanghai University Shanghai 200072 China Department of Applied Chemistry South China University of Technology Guangzhou 510640 China

The kinetics of stripping of gold loaded in dibutyl carbito （DBC） organic phase by sodittm sulfite was investigated in a Lewis cell. After the stirring speed reached 400 r·min^-1, the reaction of gold stripping conformed with the pseudo-first-order reaction. The stripping rate of gold was in direct proportion to interracial area, concentration of sodittm sulfite and reaction temperature. The experimental results showed that the process of stripping gold was controlled by interfacial chemical reaction, and its activation energy was 36.06 kJ·mol^-1. The kinetics equation was put forward for gold stripping by sodium sulfite.

关键词： kinetics stripping gold Lewis cell