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East Asian monsoon intensification promoted weathering of the magnesium-rich southern China upper crust and its global significance

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Science China Earth Sciences 2021年第7期64卷 1155-1170页

作者： Yibo YANG Albert GALY Xiaomin FANG christian france-lanord Shiming WAN Rongsheng YANG Jian ZHANG Ran ZHANG Song YANG Yunfa MIAO Yudong LIU Chengcheng YE Key Laboratory of Continental Collision and Plateau Uplift Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Tibetan Plateau Earth Sciences Beijing 100101China Centre de Recherches Pétrographiques et Géochimiques UMR7358CNRS-Universitéde LorraineVandoeuvre les Nancy 54500France University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Marine Geology and Environment Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and TechnologyQingdao 266237China Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Key Laboratory of Tibetan Environment Changes and Land Surface Processes Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China Key Laboratory of Desert and Desertification Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China

The Oligocene-Miocene boundary Asian climatic reorganization linked to the northward migration of the East Asian monsoon into subtropical China is a potentially important but poorly constrained atmospheric CO_(2) consumption ***,we performed a first-order estimate of the CO_(2) consumption induced by silicate chemical weathering and organic carbon burial in subtropical China related to this climatic *** results show that an increase in long-term CO_(2 )consumption by silicate weathering varies from 0.06×10^(12)to 0.87×10^(12)mol yr^(-1)depending on erosion flux reconstructions,with an~50%contribution of Mg-silicate weathering since the late *** organic carbon burial flux is approximately 25%of the contemporary CO_(2) consumption by silicate *** results highlight the significant role of weathering of the Mg-rich upper continental crust in East China,which would contribute to the rapid decline in atmospheric CO_(2) during the late Oligocene and the Neogene rise in the seawater Mg *** this climatic reorganization was mainly induced by the Tibetan Plateau uplift,our study suggests that the growth of the Himalayan-Tibetan Plateau can lead to indirect modification of the global carbon and magnesium cycles by changing the regional hydrological cycle in areas of East Asia that are tectonically less active.

关键词： Tibetan Plateau Late Oligocene Silicate weathering Carbon cycle Oceanic Mg cycle

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Enhanced weathering input from South Asia to the Indian Ocean since the late Eocene

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Science Bulletin 2023年第3期68卷 305-313,M0004页

作者： Zehua Song Shiming Wan Christophe Colin christian france-lanord Zhaojie Yu Arnaud Dapoigny Hualong Jin Mengjun Li Jin Zhang Debo Zhao Xuefa Shi Anchun Li Key Laboratory of Marine Geology and Environment Institute of OceanologyChinese Academy of SciencesQingdao 266071China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and TechnologyQingdao 266061China UniversitéParis-Saclay Centre National de la Recherche Scientifique(CNRS)Géosciences Paris-Saclay(GEOPS)Orsay 91405France Center for Excellence in Quaternary Science and Global Change Chinese Academy of SciencesXi’an 710061China Centre de Recherches Pétrographiques et Géochimiques(CRPG) Centre National de la Recherche Scientifique(CNRS)-Universitéde LorraineVandoeuvre les Nancy 54501France Laboratoire des Sciences du Climat et de l’Environnement LSCE/IPSLCEA-CNRS-UVSQUniversitéParis-SaclayGif-sur-Yvette 91191France Key Laboratory of Marine Sedimentology and Environmental Geology First Institute of OceanographyMinistry of Natural ResourcesQingdao 266061China

nhanced silicate weathering induced by the uplift of the Himalayan-Tibetan Plateau(HTP)has been considered as the major cause of pCO_(2) decline and Cenozoic ***,this hypothesis remains to be validated,largely due to the lack of a reliable reconstruction of the HTP weathering ***,we present a 37-million-year record of the difference in the seawater radiogenic neodymium isotopic composition(△ε_(Nd))of Ocean Drilling Program(ODP)sites and Fe-Mn crusts between the northern and central Indian Ocean,which indicates the contribution of regional weathering input from the South Asian continent to the Indian *** results show a long-term increase in △ε_(Nd) and thus provide the first critical evidence of enhanced South Asian weathering input since the late *** evolution coincided well with major pulses of surface uplift in the HTP and global climatic *** foraminiferal eNd record suggests that tectonic uplift and silicate weathering in South Asia,especially in the Himalayas,might have played a significant role in the late Cenozoic cooling.

关键词： South Asian weathering input Himalayan-Tibetan Plateau uplift Cenozoic global cooling Foraminiferal eNd record Indian Ocean ODP Site 758

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东亚季风增强加剧中国南部富Mg上地壳化学风化及其全球意义

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中国科学：地球科学 2021年第8期51卷 1289-1305页

作者：杨一博 Albert GALY 方小敏 christian france-lanord 万世明杨戎生张健张冉杨松苗运法刘玉东叶程程中国科学院青藏高原研究所大陆碰撞与高原隆升重点实验室北京100101 中国科学院青藏高原地球科学卓越创新中心北京100101 Centre de Recherches Pétrographiques et Géochimiques UMR7358CNRS-Universitéde LorraineVandoeuvre les Nancy 54500France 中国科学院大学北京100049 中国科学院海洋研究所海洋地质与环境重点实验室青岛266071 青岛海洋科学与技术试点国家实验室海洋地质过程与环境功能实验室青岛266237 中国科学院大气物理研究所气候变化研究中心北京100029 中国科学院青藏高原研究所环境变化与地表过程重点实验室北京100101 中国科学院西北生态环境资源研究院沙漠与沙漠化重点实验室兰州730000

渐新世-中新世之交的亚洲气候重组伴随着东亚季风北向推进到中国亚热带地区是一个重要的大气CO_(2)消耗过程,但是目前对该过程知之甚少.本研究近似计算了这次气候重组通过加强中国亚热带地区硅酸盐化学风化和有机碳埋藏导致的大气CO_(2... 详细信息

渐新世-中新世之交的亚洲气候重组伴随着东亚季风北向推进到中国亚热带地区是一个重要的大气CO_(2)消耗过程,但是目前对该过程知之甚少.本研究近似计算了这次气候重组通过加强中国亚热带地区硅酸盐化学风化和有机碳埋藏导致的大气CO_(2)消耗.依据侵蚀通量的重建结果,晚渐新世以来硅酸盐风化导致的长期大气CO_(2)消耗为0.06×10^(12)~0.87×10^(12)mol a^(-1),并且其中约50%的贡献来自于Mg硅酸盐风化.有机碳埋藏导致的大气CO_(2)消耗约为同时期硅酸盐风化的25%.本研究强调了中国东部富Mg上部大陆地壳风化对于晚渐新世全球大气CO_(2)含量下降和新近纪海水Mg含量增加的显著影响.如果这次气候转型主要与青藏高原隆升有关,那么本研究揭示了喜马拉雅-青藏高原的生长通过改变构造欠活跃的东亚地区水循环格局间接调控全球碳和镁循环.

关键词：青藏高原晚渐新世硅酸盐风化碳循环海洋Mg循环

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Gust response of an elasto-flexible morphing wing using fluid–structure interaction simulations

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Chinese Journal of Aeronautics 2024年第2期37卷 45-57页

作者： Jonathan PFLÜGER christian BREITSAMTER Department of Mechanical Engineering Technical University of MunichGarching 85748Germany

Small and micro unmanned aircraft are the focus of scientific interest due to their wide range of *** often operate in a highly unstable flight environment where the application of new morphing wing technologies offers the opportunity to improve flight *** investigated concept comprises port and starboard adjustable wings,and an adaptive elastoflexible membrane serves as the lifting *** focus is on the benefits of the deforming membrane during the impact of a one-minus-cosine type *** a low Reynolds number of Re=264000,the morphing wing model is investigated numerically by unsteady fluid-structure interaction ***,the numerical results are validated by experimental data from force and moment,flow field,and deformation ***,with the rigid wing as the baseline,the flexible case is investigated,focusing on the advantages of the elastic *** all configurations studied,the maximum amplitude of the lift coefficient under gust load shows good agreement between the experimental and numerical *** the decay of the gust,they differ more the higher the aspect ratio of the *** considering the flow field,the main differences are due to the separation behavior on the upper side of the *** flow reattaches earlier in the experiments than in the simulations,which explains the higher lift values observed in the *** at one intermediate configuration does the lift amplitude of the rigid configuration exceeds that of the flexible by about 12%,with the elastic membrane resulting in a smaller and more uniform peak load,which is also evident in the wing loading and hence in the root bending moment.

关键词： Membrane wing Morphing wing Flexible wing surface Computational fluid dynam-ics Fluid-structure interaction Unsteady inflow condition Gust response

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Aggresome-aggrephagy transition process:geting closer to the functional roles of HDAC6 and BAG3

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Neural Regeneration Research 2024年第6期19卷 1181-1182页

作者： Hagen Körschgen christian Behl The Autophagy Lab Institute of PathobiochemistryUniversity Medical Center of the Johannes Gutenberg University MainzMainzGermany

Misfolding of proteins as well as their aggregation is a major driver of age-related neurodegenerative ***,cells have evolved sophisticated protein quality control *** the ubiquitin-proteasome-system(UPS)and the autop... 详细信息

关键词： closer system transition

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Ray tracing particle image velocimetry-Challenges in the application to a packed bed

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Particuology 2024年第1期84卷 194-208页

作者： Christin Velten Mirko Ebert christian Lessig Katharina Zahringer Lehrstuhl für Strömungsmechanik und Strömungstechnik Otto-von-Guericke-Universität Magdeburg39106MagdeburgGermany Institut für Simulation und Graphik Otto-von-Guericke-Universität Magdeburg39106MagdeburgGermany

Ray tracing Particle Image Velocimetry(RT-PIV)is an optical technique for high resolution velocity measurements in challenging optical systems,such as transparent packed beds,that uses ray tracing to correct for distortions introduced by transparent geometries in the light *** ray tracing based correction is a post processing step applied to the raw PIV particle images before classical PIV *** this study,RT-PIV is performed in the top layer of a body centred cubic(bcc)sphere packing with gaseous flow,where optical access is obtained by the use of transparent N-BK7 glass balls with a diameter of d=40 ***-PIV introduces new experimental and numerical challenges,for example a limited field of view,illumination difficulties,a very large required depth of field and high sensitivity to geometric parameters used in the ray tracing *** challenges and their implications are the main scope and discussed in the present ***,the validation of the ray tracing reconstruction step is presented and examples for the obtained corrected vector fields in a packed bed are *** results show the strength of the method in reconstructing velocity fields behind transparent spheres that would not have been accessible by optical measurement techniques without the ray tracing correction.

关键词： Ray tracing particle image velocimetry(RT-PIV) Transparent spherical particles Packed bed Distortion correction Gas flow

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Diabetes and pulmonary infection:how hyperglycaemia shapes the immune system

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1245-1246页

作者： christian Herder Michael Roden Nicolas Venteclef Institute for Clinical Diabetology German Diabetes CenterLeibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf40225DüsseldorfGermany German Center for Diabetes Research(DZD) Partner Düsseldorf85764München-NeuherbergGermany Department of Endocrinology and Diabetology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University Düsseldorf40225DüsseldorfGermany Institut Necker-Enfants Malades(INEM) UniversitéParis CitéINSERM UMR-S1151CNRS UMR-S8253ParisFrance

In a recent study published in Nature,Nobs and colleagues aimed to identify novel mechanisms that may explain why diabetes is associated with an increased susceptibility to viral respiratory *** analyses revealed a central role of lung dendritic cells(DC)which exhibited several functional defects induced by hyperglycaemia and consequently result in impaired antiviral immune responses.

关键词： impaired lung respiratory

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Clustering of voltage-gated ion channels as an evolutionary trigger of myelin formation

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Neural Regeneration Research 2024年第8期19卷 1631-1632页

作者： Henrike Ohm Simone Rey christian Klambt Institut fur Neuro-und Verhaltensbiologie MunsterGermany

Neurons carry apical dendrites that perceive information and a basal axon that transmits the computed information towards its to *** axon originates at the axon hillock which is followed by the axon initial ***,action potentials are initiated that are based on millisecond long openings of specific voltagegated sodium and potassium channels that are conserved in all parahoxozoa(Placozoa,Cnidaria,Bilateria)(Li et al.,2015).

关键词： initiated carry potassium

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Prosaposin hyperglycosylation: a novel tumor immune escape mechanism and implications for cancer immunotherapy

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3150-3152页

作者： Matthias Peipp Diana Dudziak christian Kellner Division of Antibody-Based Immunotherapy Department of Medicine IChristian-Albrechts University and University Hospital Schleswig-HolsteinKielGermany institute of Immunology Jena University HospitalFriedrich-Schiller-UniversityJenaGermany Comprehensive Cancer Center Central Germany Jena/Leipzig JenaGermany Division of Transfusion Medicine Cell Therapeutics and HaemostaseologyLMU University HospitalLMU MunichMunichGermany

In a recent article published in Science,Sharma et *** the essential role of saposins in cross-presentation of tumor membraneassociated antigens by dendritic cells(DC)to CD8^(+)T cells.1 However,antigen cross-presentation,which is fundamental in cancer cell elimination,is hindered in tumor DC by hyperglycosylation of the common saposin precursor prosaposin(pSAP)leading to impaired T cell tumor immunity-yet,the potential of recombinant pSAP to re-establish T cell responses may offer a novel way to counteract immune evasion in a therapeutic approach.

关键词： impaired immunity al.

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A numerical and experimental comparison of heat transfer in a quasi two-dimensional packed bed

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Particuology 2024年第1期84卷 136-144页

作者： Matthias Tyslik Mirko Ebert Martin Schiemann Siegmar Wirtz christian Lessig Department of Energy Plant Technology Ruhr-University BochumGermany Institute for Simulation and Graphics Otto-von-Guericke-Universität MagdeburgGermany

Heat transfer plays a major role in many industrial processes taking place in packed *** accurate and reliable simulation of the heat exchange between particles is therefore crucial for a reliable operation and to optimize the processes in the *** discrete ordinates method(DOM)provides an established numerical technique to model radiative heat transfer in granular media that offers the possibility to consider the directional dependence of the radiation *** this work,DOM is compared with Monte Carlo ray tracing,which provides an alternative method for heat transfer ***-rically simple configurations are used to investigate the influence of the angular discretization on the accuracy of the results and the computation time in both *** obtained insights are then transferred to a more complex configuration of a quasi two-dimensional test rig consisting of metal rods for which also experimental results are *** results show that both DOM and Monte Carlo ray tracing allow for an accurate simulation of heat transfer in packed *** Carlo ray tracing requires thereby computation times that are surprisingly competitive(although still somewhat slower)compared to DOM and allows for an easier computation of highly accurate reference *** our preliminary comparison to the experimental test rig,Monte Carlo ray tracing also provides the advantage that it can more easily model highly specular materials such as stainless *** methods are comparable for diffuse materials such as magnesium oxide.

关键词： Heat transfer Discrete ordinates method Monte Carlo ray tracing

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