Aggresome-aggrephagy transition process:geting closer to the functional roles of HDAC6 and BAG3

作     者：Hagen Körschgen Christian Behl Hagen Körschgen;Christian Behl

作者机构：The Autophagy LabInstitute of PathobiochemistryUniversity Medical Center of the Johannes Gutenberg University MainzMainzGermany 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2024年第19卷第6期

页      面：1181-1182页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the Deutsche Forschungsgemeinschaft(DFG German Research Foundation)Project-ID 259130777-SFB 1177(to CB) 

主　　题：closer system transition 

摘      要：Misfolding of proteins as well as their aggregation is a major driver of age-related neurodegenerative ***,cells have evolved sophisticated protein quality control *** the ubiquitin-proteasome-system(UPS)and the autophagosome-lysosome-system,specifically a macroautophagy pathway called“aggrephagy,govern the disposal of ***.