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In vitro investigations on the effects of graphene and graphene oxide on polycaprolactone bone tissue engineering scaffolds

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Bio-Design and Manufacturing 2024年第5期7卷 651-669页

作者： Yanhao hou Weiguang Wang Paulo Bartolo School of Engineering Faculty of Science and EngineeringThe University of ManchesterManchesterUK Singapore Centre for 3D Printing School of Mechanical and Aerospace EngineeringNanyang Technological UniversitySingaporeSingapore

Polycaprolactone(PCL)scaffolds that are produced through additive manufacturing are one of the most researched bone tissue engineering structures in the *** to the intrinsic limitations of PCL,carbon nanomaterials are often investigated to reinforce the PCL *** several studies that have been conducted on carbon nanomaterials,such as graphene(G)and graphene oxide(GO),certain challenges remain in terms of the precise design of the biological and nonbiological properties of the *** paper addresses this limitation by investigating both the nonbiological(element composition,surface,degradation,and thermal and mechanical properties)and biological characteristics of carbon nanomaterial-reinforced PCL scaffolds for bone tissue engineering *** showed that the incorporation of G and GO increased surface properties(reduced modulus and wettability),material crystallinity,crystallization temperature,and degradation ***,the variations in compressive modulus,strength,surface hardness,and cell metabolic activity strongly depended on the type of ***,a series of phenomenological models were developed based on experimental results to describe the variations of scaffold’s weight,fiber diameter,porosity,and mechanical properties as functions of degradation time and carbon nanomaterial *** results presented in this paper enable the design of three-dimensional(3D)bone scaffolds with tuned properties by adjusting the type and concentration of different functional fillers.

关键词： Additive manufacturing Bone tissue engineering Carbon nanomaterial Graphene Graphene oxide Scaffold

Bioinspired nanofluidic iontronics for brain-like computing

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Nano Research 2024年第2期17卷 503-514页

作者： Lejian Yu Xipeng Li Chunyi Luo Zhenkang Lei Yilan Wang Yaqi hou Miao Wang Xu hou State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Institute of Artificial Intelligence Xiamen UniversityXiamen 361005China Department of Physics Research Institute for Biomimetics and Soft MatterFujian Provincial Key Laboratory for Soft Functional Materials ResearchJiujiang Research InstituteCollege of Physical Science and TechnologyXiamen UniversityXiamen 361005China The Higher Educational Key Laboratory for Biomedical Engineering of Fujian Province Department of BiomaterialsResearch Center of Biomedical Engineering of XiamenCollege of MaterialsXiamen UniversityXiamen 361005China The Institute of Flexible Electronics(IFE Future Technologies)Xiamen UniversityXiamen 361005China Binzhou Institute of Technology Binzhou 256600China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361102China Engineering Research Center of Electrochemical Technologies of Ministry of Education Xiamen UniversityXiamen 361005China

The human brain performs computations via a highly interconnected network of *** inspiration from the information delivery and processing mechanism of the human brain in central nervous systems,bioinspired nanofluidic iontronics has been proposed and gradually engineered to overcome the limitations of the conventional electron-based von Neumann architecture,which shows the promising potential to enable efficient brain-like *** and tunable nanofluidic ion transport behaviors and spatial confinement show promising controllability of charge carriers,and a wide range of structural and chemical modification paves new ways for realizing brain-like ***,a comprehensive framework of mechanisms and design strategy is summarized to enable the rational design of nanofluidic systems and facilitate the further development of bioinspired nanofluidic *** review provides recent advances and prospects of the bioinspired nanofluidic iontronics,including ion-based brain computing,comprehension of intrinsic mechanisms,design of artificial nanochannels,and the latest artificial neuromorphic functions ***,the challenges and opportunities of bioinspired nanofluidic iontronics in the pioneering and interdisciplinary research fields are proposed,including brain–computer interfaces and artificial neurons.

关键词： human brain ion transport nanofluidics brain-like computing memristive effect

Friendship Inference Based on Interest Trajectory Similarity and Co-occurrence

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Chinese Journal of Electronics 2024年第3期33卷 708-720页

作者： Junfeng TIAN Zhengqi hou School of Cyber Security and Computer Hebei University Hebei Key Laboratory of High Confidence Information Systems Hebei University

Most of the current research on user friendship speculation in location-based social networks is based on the co-occurrence characteristics of users,however,statistics find that co-occurrence is not common among all users;meanwhile,most of the existing work focuses on mining more features to improve the accuracy but ignoring the time complexity in practical *** this basis,a friendship inference model named ITSIC is proposed based on the similarity of user interest tracks and joint user location *** utilizing MeanShift clustering algorithm,ITSIC clustered and filtered user check-ins and divided the dataset into interesting,abnormal,and noise *** interest trajectories were constructed from user interest check-in data,which allows ITSIC to work efficiently even for users without *** the same time,by application of clustering,the single-moment multi-interest trajectory was further proposed,which increased the richness of the meaning of the trajectory *** extensive experiments on two real online social network datasets show that ITSIC outperforms existing methods in terms of AUC score and time efficiency compared to existing methods.

关键词： Data privacy Social networking (online) Noise Clustering algorithms Prediction algorithms Inference algorithms Data models

Palladium(Ⅱ)-Catalyzed Markovnikov Hydroalkynylation of Unactivated Terminal Alkenes

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Chinese Journal of Chemistry 2024年第1期42卷 29-34页

作者： Chuanqi hou Pinhong Chen Guosheng Liu Sstate Key Laboratory of Organometallic Chemistry and Shanghai Hongkong Joint Laboratory in Chemical SynthesisCenter for Excellence in Molecular SynthesisShanghai Institute of Organic ChemistryUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200032China Chang-Kung Chuang Institute East China Normal UniversityShanghai 200062China

Alkynes are versatile synthons in organic synthesis,as well as important structural moieties in bioactive ***,transition metal-catalyzed hydroalkynylation of alkenes has been developed with reactive alkenes and alkenes bearing directing ***,the regioselective hydroalkynylation of simple alkenes is still ***,we have developed a palladium-catalyzed Markovnikov hydroalkynylation of unactivated terminal alkenes,which provides an efficient approach for the synthesis of branched alkynyl compounds under mild *** reaction features excellent functional group tolerance,good reaction yields and excellent ***,the asymmetric hydroalkynylation reaction has also been achieved with moderate enantioselectivity by introducing a sterically bulky chiral Pyox ligand.

关键词： Palladium catalysis Alkynylpalladation Unactivated terminal alkenes Markovnikov hydroalkynylation

Capture Efficiency Analysis in the Circular Restricted Three-body Problem

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Research in Astronomy and Astrophysics 2024年第5期24卷 198-210页

作者： Yu-Xuan Miao Xi-Yun hou Department of Astronomy and Space Science Nanjing UniversityNanjing 210023China Institute of Space Environment and Astrodynamics Nanjing UniversityNanjing 210023China Key Laboratory of Modern Astronomy and Astrophysics Ministry of EducationNanjing 210023China

Temporary capture efficiency is studied in the framework of the circular restricted three-body problem in two ***, a non-uniform distribution of test particles around the secondary's orbit is obtained by fully accounting the secondary's gravitational influence. Second, the capture efficiency is computed based on the non-uniform distribution. Several factors influencing the result are discussed. By studying the capture efficiency in the circular restricted three-body problem of different mass ratios, a power-law relation between the capture efficiency(p) and the mass ratio(μ) is established, which is given by p ≈ 0.27 × μ^(0.53), within the range of 3.0035 ×10^(-6)≤ μ ≤ 3.0034 × 10^(-5). Taking the Sun–Earth system as an example, the influence from the orbit eccentricity of the secondary on the non-uniform distribution and the capture efficiency is studied. Our studies find that the secondary's orbit eccentricity has a negative influence on the capture efficiency.

关键词： methods numerical-celestial mechanics-planets and satellites dynamical evolution and stability

Multi-functional Hollow Structures for Intelligent Drug Delivery

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Chemical Research in Chinese Universities 2024年第3期40卷 394-412页

作者： hou Ping YANG Nailiang WANG Dan State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing 100190P.R.China School of Chemical Engineering University of Chinese Academy of SciencesBeijing 100049P.R.China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing 100049P.R.China

Multi-fountional hollow structures have emerged as promising platforms for intelligent drug delivery due to their unique properties,such as high loading capacities and programmed drug *** particular,hollow multishell structures(HoMSs)with multilevel shell and space can regulate the molecular-level interaction between drugs and materials,so as to achieve the temporal-spatial order and sequential release of *** anisotropic hollow structures can control the drug diffusion process by inducing the macroscopic interface flow through autonomous movement,realizing the targeted drug transport and *** this paper,a key focus will be HoMSs with their temporal-ordered architectures and anisotropic hollow carriers with directional *** synthesis mechanisms,structure-property relationships,smartly programmed drug delivery and biomedical applications will be discussed,providing insights into designing next-generation intelligent drug carriers.

关键词： Hollow multishell structure Anisotropic hollow structure Intelligent drug carrier Temporal-spatial order Directional movement

First Digit Distributions of Gamma-Ray Bursts

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Research in Astronomy and Astrophysics 2024年第5期24卷 70-75页

作者： hou-Yu Lai Jun-Jie Wei Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Sciences University of Science and Technology of ChinaHefei 230026China

The occurrence of the first significant digits from real world sources is usually not equally distributed,but is consistent with a logarithmic distribution instead,known as Benford’s *** this work,we perform a comprehensive investigation on the first digit distributions of the duration,fluence,and energy flux of gamma-ray bursts (GRBs) for the first *** a complete GRB sample detected by the Fermi satellite,we find that the first digits of the duration and fluence adhere to Benford’s ***,the energy flux shows a significant departure from this law,which may be due to the fact that a considerable part of the energy flux measurements is restricted by lack of spectral *** on the conventional duration classification scheme,we also check if the durations and fluences of long and short GRBs (with duration T_(90)>2 s and T_(90)≤2 s,respectively) obey Benford’s *** find that the fluences of both long and short GRBs still agree with the Benford distribution,but their durations do not follow Benford’s *** results hint that the long–short GRB classification scheme does not directly represent the intrinsic physical classification scheme.

关键词： (stars:)gamma-ray burst general-methods statistical-astronomical databases miscellaneous

Continuous Orbit Equivalence of Semigroup Actions

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1581-1598页

作者： Xiang Qi QIANG Cheng Jun hou School of Mathematical Science Yangzhou UniversityYangzhou 225002P.R.China

We introduce notions of continuous orbit equivalence and its one-sided version for countable left Ore semigroup actions on compact spaces by surjective local homeomorphisms,and characterize them in terms of the corresponding transformation groupoids and their operator *** particular,we show that two essentially free semigroup actions on totally disconnected compact spaces are continuously orbit equivalent if and only if there is a canonical abelian subalgebra preserving C^(∗)-isomorphism between the associated transformation groupoid C^(∗)-*** also give some examples of orbit equivalence,consider the special case of semigroup actions by homeomorphisms and relate continuous orbit equivalence of semigroup actions to that of the associated group actions.

关键词： Semigroup action continuous one-sided orbit equivalence continuous orbit equivalence groupoid C^(∗)-algebras

Pixel-level crack segmentation of tunnel lining segments based on an encoder–decoder network

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Frontiers of Structural and Civil Engineering 2024年第5期18卷 681-698页

作者： Shaokang hou Zhigang OU Yuequn HUANG Yaoru LIU State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China China Renewable Energy Engineering Institute Beijing 100120China State Key Laboratory of Stimulation and Regulation of Water Cycles in River Basins China Institute of Water Resources and Hydropower ResearchBeijing 100038China Hunan Provincial Water Resources Development&Investment Co. Ltd.Changsha 410007China

Regular detection and repair for lining cracks are necessary to guarantee the safety and stability of *** development of computer vision has greatly promoted structural health *** study proposes a novel encoder–decoder structure,CrackRecNet,for semantic segmentation of lining segment cracks by integrating improved VGG-19 into the U-Net *** image acquisition equipment is designed based on a camera,3-dimensional printing(3DP)bracket and two laser rangefinders.A tunnel concrete structure crack(TCSC)image data set,containing images collected from a double-shield tunnel boring machines(TBM)tunnel in China,was *** data preprocessing operations,such as brightness adjustment,pixel resolution adjustment,flipping,splitting and annotation,2880 image samples with pixel resolution of 448×448 were *** model was implemented by Pytorch in PyCharm processed with 4 NVIDIA TITAN V *** the experiments,the proposed CrackRecNet showed better prediction performance than U-Net,TernausNet,and *** paper also discusses GPU parallel acceleration effect and the crack maximum width quantification.

关键词： tunnel lining segment crack detection semantic segmentation convolutional neural network encoder-decoder structure