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Social acceptance for commercialization of genetically modified food animals

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National Science Review 2021年第8期8卷 136-137页

作者： Ziyao fan Yulian Mu Tad Sonstegard Xiaomei Zhai Kui li Perry B.Hackett Zuoyan Zhu Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences State Key Laboratory of Animal Nutrition Institute of Animal ScienceChinese Academy of Agricultural Sciences Center for Bioethics Chinese Academy of Medical Sciences and Peking Union Medical College School of Population Medicine and Public Health Peking Union Medical College Center for Genome Engineering Department of Genetics Cell Biology and Development University of Minnesota State Key Laboratory of Freshwater Ecology and Biotechnology Institute of Hydrobiology Chinese Academy of Sciences

Since late 2020, China and the United States, the world’s two largest economies,have embarked on regulatory reforms to boost the regulatory development of genetically modified food animals(GMFAs). The Ministry of Agriculture and Rural Affairs of the People’s Republic of China issued a circular to encourage original innovation of agriculturally important,

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Syntheses and Crystal Structures of Two Isomeric Au Complexes

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Chinese Journal of Structural Chemistry 2010年第7期29卷 1001-1006页

作者： YUE Cheng-Yang YIN Xiang-Chen li Bing-chao JIANG Fei-Long HONG Mao-Chun Department of Chemistry Jining University Qufu Shandong 273155 China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fuzhou Fujian 350002 China

Two new isomeric Au complexes, Au（PPh3）（bmt）, have been synthesized via the reaction of Au（PPh3）CI with 2-benzimidazolethiol （Hbmt） in dichloromethane （CH2Cl2） solution. Their crystal structures were determined by elemental analysis and single-crystal X-ray diffraction studies. Complex 1 crystallizes in the monoclinic system, space group C2/c with a = 19.589（2）, b = 21.1368（15）, c = 23.424（2） A, β = 108.346（4）°, V= 9206.1（14） A3, Mr = 1216.85, Dc = 1.756 g/cm3, μ = 6.566 mm^-1, F（000） = 4704, Z = 8, the final R = 0.0563 and wR = 0.1028 for 8125 reflections with I 〉 2σ（I）. Complex 2 crystallizes in the monoclinic system, space group P21/n with a = 9.627（3）, b = 21.384（8）, c = 22.308（8） A, β = 92.068（6）°, V= 4590（3） A3, Mr = 1216.85, Dc = 1.761 g/cms, μ = 6.585 mm^-1, F（000） = 2352, Z = 4, the final R = 0.0500 and wR = 0.0883 for 10477 reflections with I 〉 2σ（i）. X-ray diffraction studies reveal that complexes 1 and 2 both feature a 1D chain along the a axis.

关键词： 2-benzimidazolethiol isomeric gold complex

Persistent organic pollutants in global surface soils:Distributions and fractionations

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Environmental Science and Ecotechnology 2024年第2期18卷 13-27页

作者： Yi-fan li Shuai Hao Wan-li Ma Pu-Fei Yang Wen-Long li Zi-Feng Zhang li-Yan liu Robie WMacdonald International Joint Research Center for Persistent Toxic Substances(IJRC-PTS) State Key Laboratory of Urban Water Resource and EnvironmentHarbinInstitute of TechnologyHarbin150090China International Joint Research Center for Arctic Environment and Ecosystem(IJRC-AEE) Polar AcademyHarbin Institute of Technology(PA-HIT)Harbin150090China Heilongjiang Provincial Key Laboratory of Polar Environment and Ecosystem(HPKL-PEE) Harbin150090China IJRC-PTS-NA TorontoONM2J 3N8Canada College of the Environment and Ecology Xiamen UniversityXiamenChina Institute of Ocean Sciences Department of Fisheries and OceansP.O.Box 6000SidneyBCV8L 4B2Canada Centre for Earth Observation Science University of ManitobaWinnipegR3T 2N2Canada

The distribution and fractionation of persistent organic pollutants(POPs)in different matrices refer to how these pollutants are dispersed and separated within various environmental *** is a significant study area as it helps us understand the transport efficiencies and long-range transport potentials of POPs to enter remote areas,particularly polar *** study provides a comprehensive review of the progress in understanding the distribution and fractionation of *** focus on the contributions of four intermedia processes(dry and wet depositions for gaseous and particulate POPs)and determine their transfer between air and *** processes are controlled by their partitioning between gaseous and particulate phases in the *** distribution patterns and fractionations can be categorized into primary and secondary *** are developed to quantificationally study the primary and secondary distributions and fractionations of *** analysis results suggest that the transfer of low molecular weight(LMW)POPs from air to soil is mainly through gas diffusion and particle deposition,whereas high molecular weight(HMW)POPs are mainly via particle ***-POPs tend to be trapped near the source,whereas LMW-POPs are more prone to undergo long-range atmospheric *** crucial distinction elucidates the primary reason behind their temperatureindependent primary ***,the secondary distribution and fractionation can only be observed along a temperature gradient,such as latitudinal or altitudinal *** animation is produced by a one-dimensional transport model to simulate conceptively the transport of CB-28 and CB-180,revealing the similarities and differences between the primary and secondary distributions and *** suggest that the decreasing temperature trend along latitudes is not the major reason for POPs to be fractionated into the polar ecosystems,but drives the longer-term accumu

关键词： POPs Primary and secondary sources Primary and secondary emissions Primary and secondary distribution patterns Primary and secondary fractionations

Effect of micro-Al_(2)O_(3) powders on oxidation and corrosion behaviors of low-carbon MgO-C refractories

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Journal of Iron and Steel Research International 2024年第6期31卷 1522-1534页

作者： Yang Chen Zeng-yi li Hao-bo Tan Yu-ran Fu Jun Ding Cheng-ji Deng chao Yu School of Materials Science and Engineering Hunan Institute of TechnologyHengyang 421002HunanChina The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

To solve the problem of poor high-temperature service performance caused by low carbonization of MgO-C refractories,low-carbon MgO–C refractories with excellent thermal shock,oxidation and corrosion resistances were successfully designed by using SiC whiskers as reinforcing phases and introducing micro-Al_(2)O_(3) powders as *** results indicated that the addition of micro-Al_(2)O_(3) powders optimized the internal structure of the material,like the columnar β-Si_(3)N_(4) with a stepped distribution and the mosaic structure formed between granular and flaky Mg_(2)SiO_(4),which synergistically strengthened and toughened the material and gave the material excellent mechanical properties and thermal shock ***,the cold modulus of rupture and cold crushing strength after thermal shock were increased by 4.1 and 20.3 MPa,***,the addition of micro-Al_(2)O_(3) powders promoted the formation of fine particles of Mg_(2)SiO_(4),MgAl_(2)O_(4) and MgO,as well as a dense protective layer of Mg_(2)SiO_(4) in the material under high-temperature ***,spinel and high-temperature solid solution were formed in the corrosion *** oxidation and corrosion resistances were greatly improved by 41%and 15%,respectively.

关键词： Low-carbon MgO-C refractory Oxidation resistance Corrosion resistance Thermal shock resistance Micro-Al_(2)O_(3)powder

Down-regulation of the let-7i facilitates gastric cancer invasion and metastasis by targeting COL1A1

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Protein & Cell 2019年第2期10卷 143-148页

作者： Yue Shi Zipeng Duan Xun Zhang Xiaotian Zhang Guoqing Wang fan li Departme nt of Pathoge no biology The Key Laboratory of ZoonosisChinese Ministry of EducationCollege of Basic MedicineJilin UniversityChangchun 130021China The Key Laboratory for Bionics Engineering Ministry of EducationJilin UniversityChangchun 130021China

Dear Editor,Globally,gastric cancer is the most common malignant tumor and the second highest contributor to cancer deaths after lung cancer(Murray et al.,2012).Despite improved success with treatment of early stage gastric cancer(Fuse et al.,2016),the five-year survival rate of advanced staged gastric cancer patients is still *** aggressive growth characteristics of the tumor and metastasis are key factors responsible for poor overall survival in these patients(Ozkan et al.,2005).Therefore,investigation of the molecular mechanisms that underlie the aggressive behavior of gastric cancers,and identification of potential target genes for therapeutic interventions,is a key imperative.

关键词： Editor growth tumor

“1+1>2”:Highly efficient removal of organic pollutants by composite nanofibrous membrane based on the synergistic effect of adsorption and photocatalysis

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Journal of Materials Science & Technology 2022年第29期124卷 76-85页

作者： Yuanting Xu Wanting lin Dandan Yuan Shifan Chen fang li Yanping Long chao He Weifeng Zhao Changsheng Zhao College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065China Department of Polymer Science and Engineering Zhejiang UniversityHangzhou 310027China Med-X Center for Materials Sichuan UniversityChengdu 610041China College of Chemical Engineering Sichuan UniversityChengdu 610065China

Adsorption and photocatalysis are regarded as two desirable technologies for wastewater remediation,but are still unsatisfactory in removal effect,eco-friendly regeneration and facile *** this study,we developed a composite nanofibrous membrane material with excellent removal performance for organic pollutants based on synergistic adsorption and photocatalysis.A novel boron-doped,nitrogen-deficient graphitic carbon nitride(B-C3N4)photocatalyst as well as an amphiphilic copolymer of methyl methacrylate and acrylic acid(p(MMA-AA))were synthesized respectively,and then used to modify polyethersulfone for the fabrication of composite nanofibrous membrane with improved hydrophilicity,negativelycharge property and enhanced visible light response ***,the synergistic effect of adsorption and photocatalytic degradation for organic pollutants were identified especially and resulted in an excellent removal efficiency even superior to the combination of adsorption and photocatalytic degradation,which could be called a“1+1>2”*** addition,the regeneration and reusability,the purification ability for multicomponent wastewater,and the photocatalytic mechanism,were investigated and discussed *** this work,we not only prepared the nanofibrous membrane with synergistic effect of adsorption and photocatalysis,but also provided a versatile approach to design dualfunctional support material to ensure the practical applications of powdery photocatalyst in wastewater treatment.

关键词： Composite nanofibrous membrane material Wastewater remediation Photocatalytic degradation Adsorption Synergistic effect

Therapeutic effect of regulating autophagy in spinal cord injury: a network meta-analysis of direct and indirect comparisons

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Neural Regeneration Research 2020年第6期15卷 1120-1132页

作者： Duo Zhang Di Zhu fang Wang Ji-chao Zhu Xu Zhai Yuan Yuan Chen-Xi li Department of Orthopedics Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Department of Orthopedics Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Emergency Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Spinal Cord Injury Rehabilitation China Rehabilitation Research CenterBeijingChina

Objective:An increasing number of studies indicate that autophagy plays an important role in the pathogenesis of spinal cord injury,and that regulating autophagy can enhance recovery from spinal cord ***,the effect of regulating autophagy and whether autophagy is detrimental or beneficial after spinal cord injury remain ***,in this study we evaluated the effects of autophagy regulation on spinal cord injury in rats by direct and indirect comparison,in an effort to provide a basis for further *** source:Relevant literature published from inception to February 1,2018 were included by searching Wanfang,CNKI,Web of Science,MEDliNE(OvidSP),PubMed and Google Scholar in English and *** keywords included"autophagy","spinal cord injury",and"rat".Data selection:The literature included in vivo experimental studies on autophagy regulation in the treatment of spinal cord injury(including intervention pre-and post-spinal cord injury).Meta-analyses were conducted at different time points to compare the therapeutic effects of promoting or inhibiting autophagy,and subgroup analyses were also *** measure:Basso,Beattie,and Bresnahan ***:Of the 622 studies,33 studies of median quality were included in the ***,Beattie,and Bresnahan scores were higher at 1 day(MD=1.80,95%CI:0.81-2.79,P=0.0004),3 days(MD=0.92,95%CI:0.72-1.13,Pline group).Basso,Beattie,and Bresnahan scores were higher at 1 day(MD=6.48,95%CI:5.83-7.13,P<0.00001),2 weeks(MD=2.43,95%CI:0.79-4.07,P=0.004),3 weeks(MD=2.96,95%CI:0.09-5.84,P=0.04)and 4 weeks(MD=4.41,95%CI:1.08-7.75,P=0.01)after spinal cord injury with downregulation of autophagy compared w

关键词： autophagy Basso,Beattie,and Bresnahan scores indirect comparison meta-analysis nerve regeneration neural regeneration neurological function rat models regulation spinal cord injury strategy analysis

Quantitative Model for the Surface-related Electron Transfer in CdS Quantum Dots

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Chemical Research in Chinese Universities 2009年第1期25卷 17-24页

作者： HUANG chao-biao WU Chuan-liu li Shu-yan LAI Jin-ping ZHAO Yi-bing College of Chemistry and life Science Zhejiang Normal University Jinhua 321004 P. R. China Department of Chemistry and the Key Laboratory of Analytical Sciences of the Ministry of Education College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 P. R. China

The influence of surface S^2- dangling bonds and surface doped ions（Se^2-, Cu^2＋, and Hg^2＋） on the photoluminescence of Cd^2＋-rich CdS QDs was investigated. A quantitative model was proposed to understand the complex transfer processes of excited electrons in CdS QDs. The transfer of excited electrons from either the conduction band or the Cd^2＋-related trap-state to the surface S^2-related shallow hole trap-state is effective. However, the trap of excited electrons by surface doped ion trap-states from the Cd^2＋-related trap-state is more effective than that from the conduction band. The efficiency of trapping electrons from both the conduction band and the Cd^2＋-related trap-state can be quantitatively understood with the help of the proposed model. The results show that the transfer efficiency of excited electrons is dependent on the location of the energy-level of the relevant surface-related trap-state. The trap of excited electrons by the surface trap-state with energy-level closer to that of the conduction band is more effective, especially for the trap of excited electrons from Cd^2＋-related trap-state.

关键词： Photoluminescence Quantitative model CdS quantum dots Surface

Palladium-Catalyzed Desulfitative Cross-Coupling of Sodium Arylsulfinates with Aryl Bromides and Chlorides： An Alternative Convenient Synthesis of Biaryls

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Chinese Journal of Chemistry 2013年第10期31卷 1269-1273页

作者： chao Zhou Yarning li Yang Lu Rong Zhang Kun Jin Xinmei Fu Chunying Duan State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology Dalian Liaoning 116024 China

An alternative method for synthesis of biaryls has been developed through the Pd catalyzed desulfitative coupling reaction of sodium arylsulfinates with aryl bromides and chlorides. The procedure tolerates a variety of functional groups, such as cyano, formyl, acetyl, chloro, methoxy, trifluoromethyl and heteroaromatic unit. The desired products were obtained in moderate to excellent yields under relatively mild reaction conditions without additives, base or co-catalyst.

关键词： cross-coupling desulfination aryl bromides aryl chlorides palladium