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Strain Influence on the Precipitation Kinetic Nb-V Microalloyed HSLA Steel

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Journal of Iron and Steel Research International 2011年第S1期18卷 278-281页

作者： cartaya elio armando Cabrera José María Prado José Manuel Departamento de Ciencia de Materiales e Ingeniería Metalúrgica ETSEIBUniversidad Politécnica de Catalu a Av.Diagonal 64708028 BarcelonaSpain Departamento de Manufactura y Materiales Facultad de Ingeniería MecánicaUniversidad de Oriente90400 Santiago de CubaCuba Fundación CTM Centro Tecnológico Av.Bases de Manresa 108242 ManresaSpain

The strain induced effect on the precipitation kinetics of a high strength low alloy (HSLA) steel microalloyed with Nb-V was *** stress relaxation method was employed to determine the dependence of the precipitation-time-temperature curves (PTT) on previous *** tests were performed over a temperature range of 850 to 1150 oC at a constant strain rate of 0.1 s-1 at three deformation levels,namely 5,15 and 25 *** emission scanning electron microscopy (FESEM) was used to study the progress of precipitation on samples obtained by interrupted relaxation test at different *** display the acceleration kinetics at increasing *** models are discussed and compared with the present experimental results.

关键词： strain induced precipitation kinetic HSLA stress relaxation PTT

Mechatronic Design of a Robot for Upper Limb Rehabilitation at Home

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Journal of Bionic Engineering 2021年第4期18卷 857-871页

作者： elio Matteo Curcio Giuseppe Carbone Department of Mechanical Energyand Management EngineeringUniversity of Calabria Via BucciCubo 46C87036 RendeItaly

This paper addresses the design of a novel bionic robotic device for upper limb rehabilitation tasks at *** main goal of the design process has been to obtain a rehabilitation device,which can be easily portable and can be managed remotely by a professional *** allows to treat people also in regions that are not easily reachable with a significant cost *** potential benefits can be envisaged,for instance,in the possibility to keep social distancing while allowing rehabilitation treatments even during a pandemic *** attention has been devoted to design the main mechatronic components by developing specific kinematics and dynamics *** design process includes the implementation of a specific control hardware and *** experimental tests are reported to show the effectiveness and feasibility of the proposed design solution.

关键词： bionic robot design simulations parallel robots upper limb rehabilitation

Increased population density reduces body growth and female investment in a simultaneous hermaphrodite

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Current Zoology 2017年第2期63卷 151-157页

作者： elio CANNARSA Stefania MECONCELLI Department of Life Sciences and Systems Biology Universita di Torino Via Accademia Albertina 13 10123 Torino Italy.

Sex allocation theory applied to hermaphrodites assumes that there is a trade off between the alloca- tion of resources to male and female functions, within a fixed reproductive resource budget. Charnov＇s classic resource allocation model predicts a more female-biased sex allocation when competition among different sperm donors is low due to diminishing fitness returns for male investment. By manipulating the social group size, one automatically changes the population density at which individ- uals live. Increasing population density may affect reproductive allocation, leading to resource compe- tition and/or to increased concentration of harmful metabolites. This could lead to an over- or under- estimation of the individual adjustment of sex allocation responses to mating opportunities. In this article, we tested the effects of density and social group size separately on female investment and body growth （considered as proxy of the overall energy budget） in the simultaneously hermaphroditic polychaete worm Ophryotrocha diadema. We manipulated social group size （i.e., monogamous and promiscuous regimes） and density （i.e., 4 levels） using a full-factorial design, to identify the underlying factor affecting female allocation （in terms of egg production） and body growth. In contrast to findings of previous experiments, we found that an increase in population density reduced body growth and egg production of hermaphrodites irrespective of social group size. We advance the hypothesis that the increase of catabolites and oxygen consumption in high-density conditions reduces the overall resource budget and this could obscure group size effects on female fecundity.

关键词： body growth female fecundity mating group size Ophryotrocha diadema resource budget.

Early social conditions affect female fecundity in hermaphrodites

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Current Zoology 2015年第6期61卷 983-990页

作者： elio CANNARSA Mafia Cristina LORENZI Gabriella SELLA Department of Life Sciences and Systems Biology Universita di Torino Via Accademia Albertina 13 10123 Torino Italy

Social conditions experienced prior to sexual maturity influence reproduction later in life in many animals. In simulta- neous hermaphrodites, variation in mating group size influences reproductive investment. As the mating group size increases, re- productive resources devoted to the female function decrease in favor of the male function. Prior to sexual maturity, many her- maphrodites have a protandrous phase during which they produce sperm and can fertilize hermaphrodites＇ eggs. In the simulta- neously hermaphroditic polychaete worm Ophryotrocha diadema, the cost of male reproduction during adolescence is spread over the whole energy budget of worms as shown by a reduced growth rate, a delayed age at sexual maturity and the shortening of life span compared to protandrous males that do not reproduce. Little is known on whether social conditions experienced dur- ing development affect reproductive investment of immature individuals. We investigated whether social conditions affected the length of the protandrous phase, body size and also the subsequent female fecundity of same-age protandrous individuals of O. diadema, which did not had to face competition for egg fertilization. Results show that in large group sizes protandrous males lengthened their protandrous phase, slowed down body growth and decreased their individual investment at the first egg laying compared to protandrous males that were reared in isolation. In the successive egg layings worms adjusted their egg output to the current social conditions. We interpreted these results as an indication that early social conditions represent a social stress result- ing in a reduction of the overall reproductive resources up to the first egg laying .

关键词： Social stress Early experience Ophryotrocha diadema Female fecundity Social environment

Gastrointestinal and liver infections in children undergoing antineoplastic chemotherapy in the years 2000

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World Journal of Gastroenterology 2016年第25期22卷 5853-5866页

作者： elio Castagnola Eliana Ruberto Alfredo Guarino Infectious Diseases Unit Istituto Giannina Gaslini Department of Translational Medical Science Section of Pediatrics University of Naples Federico II

AIM: To review gastrointestinal and liver infections in children undergoing antineoplastic chemotherapy. To look at gut microflora features in oncology ***: We selected studies published after year 2000, excluding trials on transplanted pediatric patients. We searched English language publications in MEDLINE using the keywords: "gastrointestinal infection AND antineoplastic chemotherapy AND children", "gastrointestinal infection AND oncology AND children", "liver infection AND antineoplastic chemotherapy AND children", "liver abscess AND chemotherapy AND child", "neutropenic enterocolitis AND chemotherapy AND children", "thyphlitis AND chemotherapy AND children", "infectious diarrhea AND children AND oncology", "abdominal pain AND infection AND children AND oncology", "perianal sepsis AND children AND oncology", "colonic pseudo-obstruction A N D o n c o l o g y A N D c h i l d A N D c h e m o t h e r a p y ", "microflora AND children AND malignancy", "microbiota AND children AND malignancy", "fungal flora AND children AND malignancy". We also analysed evidence from several articles and book ***: Gastrointestinal and liver infections represent a major cause of morbidity and mortality in children undergoing antineoplastic chemotherapy. Antineoplastic drugs cause immunosuppression in addition to direct toxicity, predisposing to infections, although the specific risk is variable according to disease and host features. Common pathogens potentially induce severe diseases whereas opportunistic microorganisms may attack vulnerable hosts. Clinical manifestations can be subtle and not specific. In addition, several conditions are rare and diagnostic process and treatments are not standardized. Diagnosis may be challenging, however early diagnosis is needed for quick and appropriate interventions. Interestingly, the source of infectionin those children can be exogenous or endogenous. Indeed, mucosal damage may allow the penetrance of endogenous micr

关键词： Gastrointestinal tract Liver Microflora Infection Oncology Chemotherapy Children

Facial expression recognition using threestage support vector machines

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Visual Computing for Industry,Biomedicine,and Art 2019年第1期2卷 236-244页

作者： Issam Dagher elio Dahdah Morshed Al Shakik Computer Engineering Department University of BalamandTripoli P.O.BOX 100Lebanon

Herein,a three-stage support vector machine(SVM)for facial expression recognition is *** first stage comprises 21 SVMs,which are all the binary combinations of seven *** one expression is dominant,then the first stage will suffice;if two are dominant,then the second stage is used;and,if three are dominant,the third stage is *** multilevel stages help reduce the possibility of experiencing an error as much as *** image preprocessing stages are used to ensure that the features attained from the face detected have a meaningful and proper contribution to the classification *** expressions are created as a result of muscle movements on the *** subtle movements are detected by the histogram-oriented gradient feature,because it is sensitive to the shapes of *** features attained are then used to train the three-stage *** different validation methods were used:the leave-one-out and K-fold *** results on three databases(Japanese Female Facial Expression,Extended Cohn-Kanade Dataset,and Radboud Faces Database)show that the proposed system is competitive and has better performance compared with other works.

关键词： Facial expression recognition Support vector machine Histogram of oriented gradients Viola-Jones Validation

Chronic hepatitis C,atherosclerosis and cardiovascular disease: What impact of direct-acting antiviral treatments?

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World Journal of Gastroenterology 2018年第41期24卷 4617-4621页

作者： Luigi elio Adinolfi Luca Rinaldi Riccardo Nevola Department of Medical SurgicalNeurologicalMetabolicand Geriatric SciencesUniversity of Campania "L.Vanvitelli"

Hepatitis C virus (HCV) infection is associated with extrahepatic manifestations, among these there is an increased risk of atherosclerosis and cardiovascular disease as well as an increased cardiovascular mortality. Several direct and indirect HCV pro-atherogenic mechanisms have been proposed. HCV lives and replicates within carotid plaques, promoting a local environment of pro-atherogenic factors. In addition, it causes conditions such as insulin resistance, diabetes, hepatic steatosis, cryoglobulinemia and endotoxinemia that are associated with the development of atherosclerosis and cardiovascular disease. Therapeutic regimens based on direct-acting antiviral agents (DAA) are currently available with high efficacy in HCV clearance and improvement of liver disease, but does HCV eradication also improve atherosclerosis and the risk of cardiovascular disease? Recently, a multi-center study has shown that elimination of HCV improves carotid atherosclerosis. Two studies have shown that DAA treatments significantly reduce the risk of cardiovascular events. Several studies have assessed the impact of HCV clearance on pro-atherosclerosis metabolic conditions showing improvement in cardiovascular risk biomarkers, disappearance or improvement of insulin resistance, reduction of risk of developing diabetes and improvement of glycemic control. There are also evidences that HCV clearance promotes the recovery of cytokines and inflammatory markers associated with atherosclerosis and the disappearance of cryoglobulinemia. Available data show that clearance of HCV by DAAs is associated with an improvement in atherosclerosis and metabolic and immunological conditions that promote the development of cardiovascular disease. However, the data are not sufficient to allow definitive conclusions and further studies will be needed to definitively clarify the impact of HCV clearance on atherosclerosis and cardiovascular disease.

关键词： Direct-acting antiviral agents Hepatitis C virus Atherosclerosis Insulin resistance Cardiovascular disease

Fetal Bradyarrhythmias:Etiopathogenesis,Diagnosis and Treatment:Between Literature Review and Experience of a Tertiary Center

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Congenital Heart Disease 2021年第4期16卷 309-331页

作者： elio Caruso Silvia Farruggio Salvatore Agati Corrado Di Mambro Mediterranean Pediatric Cardiology Center“Bambino Gesù”San Vincenzo Hospital Contrada SirinaTaormina98039Italy

Fetal arrhythmias reach up around 10%of the total third-level perinatal cardiology *** bradycardia is defined as a baseline fetal heart rate(FHR)of less than 110 bpm sustained for at least 10 *** overall incidence of malignant fetal bradyarrhythmias,such as complete atrioventricular block(AVB)and channellopathies,is relatively rare,1:5000 pregnancies,but represents a serious emergency for the gynecologist,neonatologists,and pediatric *** complete AVB is strongly associated with maternal connective tissue disease,but it can be also associated with congenital heart disease and usually with a poorer prognosis with high risk of fetal hydrops and ***,the treatment of severe fetal bradyarrhythmias is principally pharmacological and aims to increase the FHR,besides an early resolution of underlying causes,when possible,and a promptly management of fetal heart *** electrostimulation nowadays is an experimental pioneering method,reserved for limited selected cases.

关键词： Fetal arrhythmias hydrops bradyarrhythmia atrioventricular block

Implementing a 1GHz Four-Issue Out-of-Order Execution Microprocessor in a Standard Cell ASIC Methodology

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Journal of Computer Science & Technology 2007年第1期22卷 1-14页

作者：胡伟武赵继业钟石强杨旭 elio Guidetti 吴永强 Key Laboratory of Computer System and Architecture Institute of Computing Technology Chinese Academy of Sciences Beijing 100080 China ST Microelectronics 39 Chemin du Camp-des-Filles 1228 Plan Les Ouates Geneva Switzerland

This paper introduces the microarchitecture and physical implementation of the Godson-2E processor, which is a four-issue superscalar RISC processor that supports the 64-bit MIPS instruction set. The adoption of the aggressive out-of-order execution and memory hierarchy techniques help Godson-2E to achieve high performance. The Godson-2E processor has been physically designed in a 7-metal 90nm CMOS process using the cell-based methodology with some bitsliced manual placement and a number of crafted cells and macros. The processor can be run at 1GHz and achieves a SPEC CPU2000 rate higher than 500.

关键词： general-purpose processor superscalar pipeline out-of-order execution non-blocking cache physical design,synthesis flow bit-sliced placement crafted cell performance evaluation