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Detailed description of Division I ice hockey concussions:Findings from the NCAA and Department of Defense CARE Consortium

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journal of Sport and Health Science 2021年第2期10卷 162-171页

作者： Kathryn L.Van Pelt jaclyn B.Caccese james T.Eckner Margot Putukian MAlison Brooks Kenneth L.cameron Megan N.Houston Matthew A.Posner jonathan C.jackson Gerald T.McGinty cameron j.hillis Thomas W.McAllister Michael A.McCrea Steven P.Broglio Thomas A.Buckley Sanders-Brown Center on Aging University of KentuckyLexingtonKY 40536-0230USA College of Medicine School of Health and Rehabilitation Sciences The Ohio State UniversityColumbusOH 43210USA Department of Physical Medicine and Rehabilitation Michigan MedicineUniversity of MichiganAnn ArborMI 48108USA University Health Services Princeton UniversityMcCosh Health CenterPrincetonNJ 08544USA Department of Orthopedics and Rehabilitation Department of PediatricsUniversity of Wisconsin School of Medicine and Public HealthMadisonWI 53705-2281USA Keller Army Hospital United States Military AcademyWest PointNY 10996USA th Medical Group United States Air Force AcademyColorado SpringsCO 80840-4000USA Sports Medicine Athletic DepartmentUnited States Air Force AcademyU.S.Air Force AcademyCO 80840-9500USA Novant Health Charlotte Independence Soccer ClubCorneliusNC 28031USA Department of Psychiatry Indiana UniversityIndianapolisIN 46202USA Neurosurgery Medical College of WisconsinMilwaukeeWI 53226USA Michigan Concussion Center University of MichiganAnn ArborMI 48109USA Kinesiology and Applied Physiology University of DelawareNewarkDE 19713USA

Objective:Since concussion is the most common injury in ice hockey,the objective of the current study was to elucidate risk factors,specific mechanisms,and clinical presentations of concussion in men’s and women’s ice ***:Ice hockey players from 5 institutions participating in the Concussion Assessment,Research,and Education Consortium were eligible for the current *** who sustained a concussion outside of this sport were *** were 332(250 males,82 females)athletes who participated in ice hockey,and 47(36 males,11 females)who sustained a ***:Previous concussion(odds ratio(OR)=2.00;95%confidence interval(95%CI):1.02‒3.91)was associated with increased incident concussion odds,while wearing a mouthguard was protective against incident concussion(OR=0.43;95%CI:0.22‒0.85).Overall,concussion mechanisms did not significantly differ between *** were specific differences in how concussions presented clinically across male and female ice hockey players,***(9.09%)were less likely than males(41.67%)to have a delayed symptom onset(p=0.045).Additionally,females took significantly longer to reach asymptomatic(p=0.015)and return-to-play clearance(p=0.005).Within the first 2 weeks post-concussion,86.11%of males reached asymptomatic,while only 45.50%of females reached the same phase of *** males(91.67%)were cleared for return to play within 3 weeks of their concussion,compared to less than half(45.50%)of ***:The current study proposes possible risk factors,mechanisms,and clinical profiles to be validated in future concussions studies with larger female sample *** specific risk factors,concussion mechanisms,and clinical profiles of concussion in collegiate ice hockey may generate ideas for future concussion prevention or intervention studies.

关键词： Concussion risk Injury mechanism Recovery

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Optimizing oncolytic virus design:a“Swiss army knife”approach to create a systemically delivered therapeutic

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Signal Transduction and Targeted Therapy 2024年第5期9卷 1791-1792页

作者： Carolina S.Ilkow john cameron Bell Ottawa Hospital Research Institute 501 Smyth RoadOttawaONK1H 8L6Canada

In a recent paper published in Nature Biotechnology,Chen et al.1 describe a multiplex oncolytic virus platform that coupled with adoptive T cell therapy could solve the problem of repeat,systemic delivery of virus based *** is widely accepted that multi-targeted therapeutic approaches attacking several facets of cancer biology are necessary to effectively deal with the tumor heterogeneity that exists within and between patients.

关键词： therapeutic al. targeted

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Comparative utility of vestibular function tests in patients with peripheral and central vestibular dysfunction

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journal of Otology 2024年第1期19卷 5-9页

作者： cameron B.Fattahi Christopher Zaro janice j.Chung Richard F.Lewis Divya A.Chari Department of Otolaryngology-Head and Neck Surgery UMASS Memorial Medical CenterUniversity of Massachusetts Chan Medical SchoolWorcesterMAUSA jenks Vestibular Physiology Laboratory Massachusetts Eye and EarBostonMAUSA Department of Otolaryngology-Head and Neck Surgery Massachusetts Eye and EarHarvard Medical SchoolBostonMAUSA Department of Neurology Harvard Medical SchoolBostonMAUSA

Background: Bithermal caloric irrigation, video head impulse test(vHIT), and rotational testing are commonly used to assess peripheral vestibular function, but the relative clinical utility of each test in differentiating patients with peripheral vestibulopathy is ***: To determine whether(1) the combination of two or more vestibular tests enhances diagnostic utility over a single test;(2) abnormal test results on vestibular tests correlate with one ***: Retrospective analysis of data collected from multidisciplinary vestibular clinics at two academic medical centers from 2016 to ***: 150 patients(54.10 ± 15.09 years, 88 females) were included. No individual test was significantly better at predicting the presence of peripheral vestibular damage(p > 0.05). vHIT test results improved significantly when combined with either the caloric test(p = 0.007) or rotary chair test(p = 0.039). Caloric and rotational testing had high sensitivity(74.65% and 76.06%, respectively) and specificity(83.54% and 78.48%, respectively). vHIT demonstrated excellent specificity(89.87%) but poor sensitivity(47.89%). Caloric, vHIT, and rotary chair tests results did not correlate with one another(p > 0.05).Conclusions: Vestibular function tests have comparable diagnostic utility, yet each offers unique advantages. Caloric and rotational testing may be best suited for screening peripheral damage and vHIT may function ideally as a confirmatory test.

关键词： vestibular patients specificity

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A randomized controlled trial of Promoting Physical Activity in Regional and Remote Cancer Survivors(PPARCS)

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journal of Sport and Health Science 2024年第1期13卷 81-89页

作者： Sarah j.Hardcastle Chloe Maxwell-Smith Vinicius Cavalheri Terry Boyle Marta Leyton Román cameron Platell Michael Levitt Christobel Saunders Frank Sardelic Sophie Nightingale jacob McCormick Craig Lynch Paul A.Cohen Max Bulsara Dana Hince Sport and Physical Activity Research Centre Sheffield Hallam UniversitySheffieldS102BPUK Institute for Health Research The University of Notre DameFremantleWA 6959Australia Curtin School of Population Health Curtin UniversityPerthWA 6845Australia Curtin School of Allied Health Curtin UniversityPerthWA 6845Australia Allied Health South Metropolitan Health ServiceMurdochWA 6150Australia Australian Centre for Precision Health University of South AustraliaAdelaideSA 5001Australia Department of Didactics of Musical Plastic and Body ExpressionUniversity of ExtremaduraCaceres 10071Spain St.john of God Subiaco Hospital PerthWA 6008Australia Department of Surgery University of MelbourneMelbourneVIC 3010Australia Tamara Private Hospital TamworthNSW 2340Australia Peter MacCallum Cancer Centre MelbourneVIC 3000Australia College of Health and Medicine Australian National UniversityCanberraACT 2600Australia Division of Obstetrics and Gynaecology Medical SchoolUniversity of Western AustraliaPerthWA 6009Australia

Background:Physical activity(PA)is important for cancer *** of remotely delivered interventions are needed to assist in reaching under-served non-metropolitan cancer *** objective of this study was to ascertain whether wearable technology,coupled with health coaching was effective in increasing PA in breast and colorectal cancer survivors living in regional and remote areas in ***:Cancer survivors from 5 states were randomized to intervention and control *** participants were given a Fitbit Charge 2TMand received up to 6 telephone health coaching *** participants received PA print *** assessments at baseline and 12 weeks measured moderate-to-vigorous PA(MVPA),light PA,and sedentary ***:Eighty-seven participants were recruited(age=63±11 years;74(85%)female).There was a significant net improvement in MVPA of 49.8 min/week,favoring the intervention group(95%confidence interval(95%CI):13.6-86.1,p=0.007).There was also a net increase in MVPA bouts of 39.5 min/week(95%CI:11.9-67.1,p=0.005),favoring the intervention *** groups improved light PA and sedentary behavior,but there were no between-group ***:This’s the first study to demonstrate that,when compared to standard practice(i.e.,PA education),a wearable technology intervention coupled with distance-based health coaching,improves MVPA in non-metropolitan cancer *** results display promise for the use of scalable interventions using smart wearable technology in conjunction with phone-based health coaching to foster increased PA in geographically disadvantaged cancer survivors.

关键词： Behavior change Exercise Health disparities Oncology Wearable technology

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An electropenetrography waveform library for the probing and ingestion behaviors of Culex tarsalis on human hands

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Insect Science 2024年第4期31卷 1165-1186页

作者： Anastasia M.W.Cooper Samuel B.jameson Victoria Pickens cameron Osborne Elaine A.Backus Kristopher Silver Dana N.Mitzel Department of Entomology Kansas State UniversityManhattanKansasUSA Department of Tropical Medicine Tulane University School of Public Health and Tropical MedicineNew OrleansLos AngelesUSA USDA Agricultural Research Service San Joaquin Valley Agricultural Sciences CenterParlierCaliforniaUSA National Bio and Agro-Defense Facility USDA Agricultural Research ServiceManhattanKansasUSA

Culex tarsalis Coquillett(Diptera:Culicidae)mosquitoes are capable of vectoring numerous pathogens affecting public and animal ***,the probing behaviors of mosquitoes are poorly understood because they occur in opaque ***(EPG)has the potential to elucidate these behaviors by recording the electrical signals generated during *** used an AC–DC EPG with variable input resistors(Ri levels)to construct a waveform library for *** feeding on human *** events associated with mosquito probing were used to characterize waveforms at four Ri levels and with two electrical current *** optimal settings for EPG recordings of *** probing on human hands was an Ri level of 10^(7)Ohms using an applied signal of 150 millivolts alternating *** for *** included those previously observed and associated with probing behaviors in Aedes aegypti L.(Diptera:Culicidae):waveform families j(surface salivation),K(stylet penetration through the skin),L(types 1 and 2,search for a blood vessel/ingestion site),M(types 1 and 2,ingestion),N(type 1,an unknown behavior which may be a resting and digestion phase),and W(withdrawal).However,we also observed variations in the waveforms not described in ***,which we named types L3,M3,M4,and *** investigation enhances our understanding of mosquito probing *** also provides a new tool for the automated calculation of peak *** work will facilitate future pathogen acquisition and transmission studies and help identify new pest and disease management targets.

关键词： AC-DC blood feeders electrical penetration graph EPG human hands mosquitoes waveform library

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Why Literature? A Profession

Why Literature? A Profession

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文明的和谐与共同繁荣——北京论坛（2004）

作者： j.hillis Miller Department of English and Comparative Literature University of California

I turned to literature from science.I had intended to be a *** shift defined to some degree the form my interest in literature *** interest has always been *** the one hand,I have an immense pleasure and investment in reading literature.A literary work is for me the magic entry into an imaginary world or,as I would call it now and as other people also might,a virtual *** the imaginary,for some

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Why Literature Matters to Me

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中国比较文学 2013年第4期 71-83页

作者： j. hillis Miller University of California at Irvine USA

我一直很看重对文学作品的细读,对我而言,文学理论是辅助性的。尽管文学曾对西方和全球都有至关重要的作用,新的交流技术的兴起已经剧烈地改变了文学的社会地位。我对文学的兴趣始自大学时代,文学作品的意义至今仍令我痴迷。电影、电视... 详细信息

我一直很看重对文学作品的细读,对我而言,文学理论是辅助性的。尽管文学曾对西方和全球都有至关重要的作用,新的交流技术的兴起已经剧烈地改变了文学的社会地位。我对文学的兴趣始自大学时代,文学作品的意义至今仍令我痴迷。电影、电视、因特网、万维网、电子邮件、iPhone及iPad意味着今日文学对人们所思所信的影响已经式微,这种情况已经以不同的方式、在不同的程度上在全球各地发生。大学里老式的研究文学的方式今天似乎在中国比在美国更加繁荣。文学阅读的训练有助于人们更好地理解大众媒介。而且,文学仍然是人类满足其居留于想象世界之需求的无与伦比的方式。

关键词：细读迷惑新交流技术想象世界中国的文学研究

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当今的图像与文本（英文）

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外国文学研究 2019年第4期41卷 16-23页

作者： j·希利斯·米勒加州大学尔湾分校美国艺术与科学院美国哲学院

图像通常是这样或那样的视觉展现,要不就是某样东西的'图像',如同'摄影图像'。不过,有时候一个图像也许是'单一体',一幅不带任何相关意义的图像。文本通常是一系列富有意义的词语,按照可以理解的顺序排列而成。本文探索新近媒体的变化... 详细信息

图像通常是这样或那样的视觉展现,要不就是某样东西的'图像',如同'摄影图像'。不过,有时候一个图像也许是'单一体',一幅不带任何相关意义的图像。文本通常是一系列富有意义的词语,按照可以理解的顺序排列而成。本文探索新近媒体的变化尤其是无所不在的数字化对阅读的影响。文章以波提切利和沃霍尔的图像文本为例,认为我们需要改变所谓的'修辞阅读',以便解读文本与图像的新数码化组合,如电子游戏。

关键词：图像文本波提切利沃霍尔修辞阅读数码化电子游戏

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Numerical study of roll motion of a 2-D floating structure in viscous flow

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journal of Hydrodynamics 2016年第4期28卷 544-563页

作者： Lifen CHEN Liang SUN jun ZANG A.j.hillis A.R.PLUMMER WEIR Research Unit Department of Architecture and Civil EngineeringUniversity of Bath Department of Mechanical Engineering University of Bath

In the present study,an open source CFD tool,Open FOAM has been extended and applied to investigate roll motion of a 2-D rectangular barge induced by nonlinear regular waves in viscous *** of the present Open FOAM results with published potential-flow solutions and experimental data have indicated that the newly extended Open FOAM model is very capable of accurate modelling of wave interaction with freely rolling *** wave-induced roll motions,hydrodynamic forces on the barge,velocities and vorticity fields in the vicinity of the structure in the presence of waves have been investigated to reveal the real physics involved in the wave induced roll motion of a 2-D floating *** analysis has been carried out to examine the effect of structure dimension and body draft on the roll motion.

关键词： floating normalized rectangular capable viscous vorticity draft modelling rotating hydrodynamic

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Asymmetric biotic interchange across the Bering land bridge between Eurasia and North America

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National Science Review 2019年第4期6卷 739-745页

作者： Dechun jiang Sebastian Klaus Ya-Ping Zhang David M.hillis jia-Tang Li CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization & Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of Biology Chinese Academy of Sciences Department of Ecology and Evolution J.W.Goethe University State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences CAS Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences Department of Integrative Biology and Biodiversity Center University of Texas at Austin

The exchange of biotas between Eurasia and North America across the Bering land bridge had a major impact on ecosystems of both continents throughout the Cenozoic. This exchange has received particular attention regarding placental mammals dispersing into the Americas, including humans after the last glacial period, and also as an explanation for the disjunct distribution of related seed plants in eastern Asia and eastern North America. Here, we investigate bi-directional dispersal across the Bering land bridge from estimates of dispersal events based on time-calibrated phylogenies of a broad range of plant, fungus and animal taxa. We reveal a long-lasting phase of asymmetrical biotic interchange, with a peak of dispersal from Asia into North America during the late Oligocene warming(26–24 Ma), when dispersal in the opposite direction was greatly decreased. Influx from North America into Asia was lower than in the opposite direction throughout the Cenozoic, but with peak rates of dispersal at the end of the Eocene(40–34 Ma)and again in the early to middle Miocene(16–14 Ma). The strong association between dispersal patterns and environmental changes suggests that plants, fungi and animals have likely dispersed from stable to perturbed environments of North America and Eurasia throughout the Cenozoic.

关键词： multiple taxa biogeography Bering land bridge Cenozoic

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