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Advances in Atmospheric Sciences 2009年第2期26卷 222-228页

作者： Myoung-Joo LEE Ki-ho CHANG Gyun-Myoung PARK Jin-Yim JEONG Ha-Young YANG Ki-Deok JEONG Joo-Wan CHA Sung-Soo YUM Jae-Cheol nam Kyungsik KIM byung-Chul ChoI National Institute of Meteorological Research Korea Meteorological Administration Department of Atmospheric Sciences Yonsei University Department of Physics Pukyong National University

The snow enhancement experiments, carried out by injecting AgI and water vapor into orographically enhanced clouds （fog）, have been conducted to confirm Li and Pitter＇s forced condensation process in a natural situation. Nine ground-based experiments have been conducted at Daegwallyeong in the Taebaek Mountains for the easterly foggy days from January-February 2006. We then obtained the optimized conditions for the Daegwallyeong region as follows： the small seeding rate （1.04 g min-1） of AgI for the easterly cold fog with the high humidity of Gangneung. Additional experiments are needed to statistically estimate the snowfall increment caused by the small AgI seeding into the orographical fog （cloud） over the Taeback Mountains.

关键词： snow enhancement experiment cold cloud modification forced condensation AgI seeding orographical supersaturation

Laser-induced plasma generated by a 532nm pulsed laser in bulk water:unexpected line-intensity variation with water temperature and the possible underlying physics

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Plasma Science and Technology 2020年第7期22卷 65-74页

作者： Sandeep KUMARI Jeong PARK Sang-ho nam Song_Hee HAN Yonghoon LEE Department of Chemistry Mokpo National UniversityJeonnam 58554Republic of Korea Division of Navigation Science Mokpo National Maritime UniversityJeonnam 58628Republic of Korea

The effect of the matrix temperature on laser-induced plasma generated in bulk water by using a532 nm pulsed laser beam has been *** Ⅰ and Ⅱ emission line intensities were recorded for an aqueous solution of CaCl2 in the temperature range of 7℃-70℃.The emission line intensities did not follow the matrix temperature in our *** intensities were observed at ~18℃ for both ***,a possible mechanism responsible for the observed variation in intensity is suggested,in which laser-produced bubbles play important *** formation is essential to ignite plasma in the liquid and more feasible at the higher liquid ***,the abundant bubbles at the higher temperature can scatter the incident laser beam more effectively to decrease the energy delivered for the laser-induced ***,these two roles have effects on the optical emission intensities in opposite *** validity of the suggested mechanism is discussed based on the plasma temperature,temperature dependence of the refractive index of water,plasma electron density,scattered light intensity,and plasma ignition threshold *** result indicates that the temperature of the liquid is also an important parameter to be considered in the laser-induced breakdown spectroscopy analysis of bulk liquid samples and its application in deep-sea exploration.

关键词： laser-induced breakdown spectroscopy liquid analysis laser-produced bubble

A Nearly Analytic Discrete Method for One-dimensional Unsteady Convection-dominated Diffusion Equations

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Communications in Mathematical Research 2019年第3期35卷 193-207页

作者： KIM YON-ChoL YUN nam CHAI DONG-ho Institute of Mathematics Academy of Sciences of DPR Korea

In this paper, a nearly analytic discretization method for one-dimensional linear unsteady convection-dominated diffusion equations and viscous Burgers’ equation as one of the nonlinear equation is considered. In the case of linear equations, we find the local truncation error of the scheme is O(τ 2 + h4) and consider the stability analysis of the method on the basis of the classical von Neumann’s theory. In addition, the nearly analytic discretization method for the one-dimensional viscous Burgers’ equation is also constructed. The numerical experiments are performed for several benchmark problems presented in some literatures to illustrate the theoretical results. Theoretical and numerical results show that our method is to be higher accurate and nonoscillatory and might be helpful particularly in computations for the unsteady convection-dominated diffusion problems.

关键词： convection-dominated diffusion equation nearly analytic discretization method analysis of the stability

高密度Ralstonia eutropha细胞培养过程中二氧化碳的生成及其抑制作用

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高校化学工程学报 2004年第5期18卷 633-637页

作者：尚龙安范代娣 ho nam Chang 西北大学化工系陕西西安710069 韩国科学技术院生命化学工程系韩国大田305-701

测定了高密度R. eutropha细胞培养过程中二氧化碳的生成量。当通气量维持在1.0vvm时,出口气体中二氧化碳的最大浓度高达15%。为了了解高密度细胞培养过程中二氧化碳对细胞生长代谢可能产生的抑制作用,通过施加不同浓度、不同持续时间的... 详细信息

测定了高密度R. eutropha细胞培养过程中二氧化碳的生成量。当通气量维持在1.0vvm时,出口气体中二氧化碳的最大浓度高达15%。为了了解高密度细胞培养过程中二氧化碳对细胞生长代谢可能产生的抑制作用,通过施加不同浓度、不同持续时间的二氧化碳脉冲,模拟测试了5升发酵罐内二氧化碳对R. eutropha细胞生长代谢的抑制作用。实验发现,二氧化碳对细胞生长的抑制作用随着二氧化碳脉冲时间的增长和浓度的增高而增强。当在细胞指数生长初期施加6小时浓度为22%的二氧化碳脉冲,最终细胞浓度降低了31%。

关键词：高密度细胞培养二氧化碳抑制作用二氧化碳生成 Ralstonia eutropha

Down-regulation of tyrosinase,TRP-1,TRP-2 and MITF expressions by citrus press-cakes in murine B16 F10 melanoma

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Asian Pacific Journal of Tropical Biomedicine 2013年第8期3卷 617-622页

作者： Sang Suk Kim Min-Jin Kim Young Hun Choi byung Kuk Kim Kwang Sik Kim Kyung Jin Park Suk Man Park nam ho Lee Chang-Gu Hyun Cosmetic Science Center Department of ChemistryJeju National UniversityJeju 690-756Korea Citrus Research Station National Institute of Horticultural & Herbal ScienceRDAJeju 699-946Korea Jeju Technopark Ara-1-dongJeju-siJeju 690-121Korea Ohyun High School 1 Hwabook-dongJeju-siJeju 690-061Korea LINC Agency Jeju National UniversityAra-1-dongJeju 690-756Korea

Objective:To investigate the suitability of citrus-press cakes,by-products of the juice industry as a source for the whitening agents for cosmetic ***:Ethylacetate extracts of citrus-press cakes(CCE)were examined for their anti-melanogenic potentials in terms of the inhibition of melanin production and mechanisim of melanogenesis by using Western Blot analysis with tyrosinese,tyrosinase-related protein-1(TRP-1),TRP2,and microphthalmia-associated transcription factor(MITF)*** apply the topical agents,citrus-press cakes was investigated the safety in human skin cell *** flavonoid analysis of CCE was also determined by HPLC ***:Results indicated that CCE were shown to down-regulate melanin content in a dose-dependent *** CCE inhibited tyrosinase,TRP-2,and MITF expressions in a dose-dependent *** test the applicability of CCE to human skin,we used MTT assay to assess the cytotoxic effects of CCE on human keratinocyte HaCaT *** CCE exhibited low cytotoxicity at 50μg/*** of the citrus-press cakes for flavonoid contents using HPLC showed varied quantity of rutin,narirutin,and ***:Considering the anti-melanogenic activity and human safety,CCE is considered as a potential anti-melanogenic agent and may be effective for topical application for treating hyperpigmentation disorders.

关键词： Citrus-press cakes Melanin Melanogenesis Tyrosinase MITF TRP-1 TRP-2

Effect of Isothermal Annealing on Nano Ti-Carbides Precipitation

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Journal of Iron and Steel Research International 2011年第S1期18卷 287-289页

作者： Cheol-ho Park Woo-jin Kim nam-hyun Kang Hyung-hyup Do Kyung-Mox Cho Department of Materials Science and Engineering Pusan National UniversityBusan 609-735Korea Technical Research Laboratories Hyundai steelsDangjinChungnam 343-711Korea

Transmission electron microscopy was used to investigate the effect of isothermal holding temperature and time on the nano Ti-precipitates.A holding temperature was varied systematically from 400℃ to 1200℃.The isothermal holding was continued for 30s,300s and 900s,*** carbides of (Ti,Nb)C were precipitated significantly at 900℃.The size of carbides was approximately 10nm at 30s holding and increased to 20～30nm at 900s *** holding at 1000℃ showed the increased amount of carbides larger than *** 800℃,nano (Ti,Nb)C was not observed at 30s and it was examined at *** size of nano (Ti,Nb)C was smaller than that of 900℃.As the isothermal temperature decreased to 700 ℃,the nano (Ti,Nb)C was only seen at 900s holding and the size of carbides was smaller than *** (Ti,Nb)C was disappeared at isothermal holding below 600℃.The kinetics of nano (Ti,Nb)C precipitation were studied as a function of isothermal holding temperature and time,respectively,using the precipitate growth equations.

关键词： Ti carbide hot rolled steel hole expansion ratio isothermal holding nano precipitates

Effect of solution treatment and artificial aging on microstructure and mechanical properties of Al-Cu alloy

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Transactions of Nonferrous Metals Society of China 2013年第3期23卷 631-635页

作者： Jae-ho JANG Dae-Geun nam Yong-ho PARK Ik-Min PARK Korea Institute of Industrial Technology Busan 618-230Korea School of Material Science and Engineering Pus an National UniversityBusan 609-735Korea

In order to achieve good mechanical properties of Al-Cu alloys such as high strength and good toughness,precipitation hardening and artificial aging treatment were *** defined by the T6 heat treatment,the standard artificial aging treatment for Al-Cu alloy followed heat treatments of solution treatment at 510-530 ℃ for 2 h,quenching in water at 60 ℃ and then artificial aging at 160-190 ℃ for 2-8 *** effects of solution treatment and artificial aging on the microstructure and mechanical properties of Al-Cu alloy were studied by optical microscopy（OM）,scanning electron microscopy（SEM）,energy dispersive X-ray spectroscopy（EDS）,transmission electron microscopy（TEM） and tensile *** results of solution treatment indicate that the mechanical properties of Al-Cu alloy increase and then decrease with the increase of solution *** is because the residual phases dissolve gradually into the matrix,and the fraction of the precipitation and the size of the re-crystallized grain *** to the solution temperature,the solution holding time has less effect on the microstructure and the mechanical properties of Al-Cu *** artificial aging treatments were conducted at 160-180 ℃ for 2-8 *** results show that the ultimate tensile strength can be obtained at 180 ℃ for 8 *** tensile strength increased with increasing time or *** strength was found as the same as the ultimate tensile strength result.

关键词： Al-Cu alloy solid solution treatment artificial aging microstructure mechanical property

Uhwang Chungsim Won Decreases Blood Oxygen Level-Dependent fMRI Signal Response to A Motor Stimulation Task

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Chinese Journal of Integrative Medicine 2015年第7期21卷 493-499页

作者： Woo-Sang Jung Jong-Man Ryu Young-Jee Kim Seong-Uk Park Geon-ho Jahng Jung-Mi Park Sang-Kwan Moon Chang-nam Ko Ki-ho Cho Department of Cardiovascular&Neurologic Diseases(Stroke Center) College of Oriental MedicineKyung Hee University Department of Radiology College of MedicineKyung Hee University

Objectives： TO evaluate the effect of Uhwang Chungsim Won [UC, Niuhuang Qingxin Pill （牛黄清心丸] on the blood oxygen level-dependent （BOLD） functional magnetic resonance imaging （fMRI） signal response to a motor stimulation task using a hand grasping paradigm. Methods： Ten healthy right-handed male volunteers were recruited. Their BOLD fMRI signal characteristics during hand grasping were determined before and 1 h after consuming UC. Results： With the administration of UC, BOLD responses to the right hand motor task showed a decrease in both hemispheres including the right cerebellar culmen, right and left medial frontal gyrus, right parahippocampal gyrus, right and left sublobar insula, right and left posterior cingulate, left precuneus, and right precentral gyrus. Decreased BOLD responses to the left hand motor task were shown in the right lingual gyrus, right cerebellar culmen, left superior temporal gyrus, right and left middle frontal gyrus, and right precentral gyrus after UC administration. Increased BOLD responses to the left hand motor task were shown in the left and right posterior cingulate, while there was no increased response to the right hand motor task after UC administration. Conclusions： UC administration significantly decreased fMRI BOLD signal responses to hand grasping in most of the brain areas including the primary motor cortex, but it is not clear whether these decreased responses were caused by a decrease in neuronal activities or by an increase in cerebral blood flow due to the cerebral vasodilatory effects of UC. Further studies using positron emission tomography or single photon emission computed tomography are needed to fully elucidate these findings.

关键词： Uhwang Chungsim Won Niuhuang Qingxin Pfll pharmacological fMRI cerebral blood flow

Inhibitory Mechanisms of Water Extract of Oplopanax elatus on Lipopolysaccharide-lnduced Inflammatory Responses in RAW 264.7 Murine Macrophage Cells

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Chinese Journal of Integrative Medicine 2020年第9期26卷 670-676页

作者： Ki Sun Kwon Hyun Lim Yong Soo Kwon Myong Jo Kim Ji Hye Yoo nam ho Yoo Hyun Pyo Kim College of Pharmacy Kangwon National UniversityChuncheon(24341)Republic of Korea Department of Bio-Resource Sciences Kangwon National UniversityChuncheon(24341)Republic of Korea Bioherb Research Institute Kangwon National UniversityChuncheon(24341)Republic of Korea

Objective:To study the anti-inflammatory action and cellular mechanism of Oplopanax ***:A hot water extract of OE(WOE)was prepared and a major constituent,syringin,was successfully *** content in WOE was found to be 214.0 p.g/g dried plant(w/w).Their anti-inflammatory activities were examined using RAW 264.7 macrophages and a mouse model of croton oil-induced ear ***:In lipopolysaccharide(LPS)-treated RAW 264.7 cells,a mouse macrophage cell line,WOE was found to significantly and strongly inhibit cyclooxygenase-2(COX-2)-induced prostaglandin E2(PGE2)production[half maximal inhibitory concentration(IC50)=135.2μg/mL]and inducible nitric oxide synthase(iNOS)-induced NO production(IC50=242.9μg/mL).In the same condition,WOE was revealed to inhibit NO production by downregulating iNOS expression,mainly by interrupting mitogen activated protein kinases(MAPKs)/activator protein-1(AP-1)*** activation of all three major MAPKs,p38 MAPK,extracellular signal-regulated kinase(ERK),and c-Jun N-terminal kinase,was inhibited by WOE(50-300μg/mL).On the other hand,WOE reduced PGE2 production by inhibiting COX-2 enzyme activity,but did not affect COX-2 expression *** addition,WOE inhibited the production of proinflammatory cytokines such as interleukin-6 and tumor necrosis factor-α.In croton oil-induced ear edema in mice,oral administration of WOE(50-300 mg/kg)dose-dependently inhibited edematic ***:Water extract of OE exhibited multiple anti-inflammatory action mechanisms and may have potential for treating inflammatory disorders.

关键词： Oplopanax elatus Chinese medicine stem syringin anti-inflammation RAW 264.7

Sorption enhanced catalytic CF4 hydrolysis with a three-stage catalyst-adsorbent reactor

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Frontiers of Chemical Science and Engineering 2017年第4期11卷 537-544页

作者： Jae-Yun Han Chang-Hyun Kim Boreum Lee Sung-Chan nam ho-Young Jung Hankwon Lim Kwan-Young Lee Shin-Kun Ryi . Advanced Materials and Devices Laboratory Korea Institute of Energy Research (KIER) Daejeon 34129 Korea.. Department of Advanced Materials and Chemical Engineering Catholic University of Daegu Gyeongbuk 38430 Korea.. Department of Environment and Energy Engineering Chonnam National University Gwangju 61186 Korea.. Department of Chemical and Biological Engineering Korea University Seoul 136-701 Korea

In this study, we developed a three-stage catalyst-adsorbent reactor for the catalytic hydrolysis of CF4. Each stage is composed of a catalyst bed followed by an adsorbent bed using Ca（OH）2 to remove HF. The three stages are connected in series to enhance the hydrolysis of CF4 and eliminate a scrubber to dissolve HF in water at the same time. With a 10 wt-% Ce/AlaO3 catalyst prepared by the incipient wetness method using boehmite and a granular calcium hydroxide as an adsorbent, the CF4 conversion in our proposed reactor was 7%-23% higher than that in a conventional single-bed catalytic reactor in the temperature range of 923-1023 K. In addition, experimental and numerical simulation （Aspen HYSYS） results showed a reasonable trend of increased CF4 conversion with the adsorbent added and these results can be used as a useful design guideline for our newly proposed multistage reactor system.

关键词： PFCs catalytic hydrolysis calcium hydro-xide sorption enhanced process simulation