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Chinese Journal of Oceanology and Limnology 2016年第1期34卷 170-176页

作者：寇琦李新正 Alexander J.bruce Institute of Oceanology Chinese Academy of Sciences Crustacea Section Queensland Museum

A new genus of the deep-sea pontoniine shrimps,Bathymenes gen. nov.,is established for the 'Periclimenes alcocki species group' of the genus Periclimenes Costa,1844. The new genus is distinguished from other genera of the Pontoniinae by a combination of characters: the posteriormost dorsal rostral tooth remote from other teeth,situated in the epigastric position,cornea usually reduced,the propodus of second pereiopods covered with fine granules,the dactylus of the major second chela being generally flanged,the ambulatory pereiopods with the dactyli being biunguiculate and telson with more than two pairs of dorsolateral spines. The genus is mainly distributed in the tropical to warm-temperate Indo-West Pacific waters at depths greater than 200 m. Fifteen species previously recognized as belonging to the 'P.a lcocki species group' are now placed in Bathymenes gen. nov. A key for their identification and a checklist of congeneric species are provided.

关键词：长臂虾科物种深海种群清单十足目配给太平洋海域

Hepatobiliary manifestations following two-stages elective laparoscopic restorative proctocolectomy for patients with ulcerative colitis:A prospective observational study

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World Journal of Gastrointestinal Surgery 2023年第2期15卷 234-248页

作者： Tamer A A m Habeeb Abdulzahra Hussain mauro Podda Pasquale Cianci bruce Ramshaw Khaled Safwat Wesam m Amr Tamer Wasefy Alaa A Fiad mohamed Ibrahim mansour Adel mahmoud moursi GamalOsman Anass Qasem mohamed Fawzy mohamed Ibrahim Abo Alsaad Abd-Elfattah Kalmoush mohammedShaaban Nassar Fawzy m mustafa mahmoud Hassib morsi Badawy Ahmed Hamdy Hamdi Elbelkasi Bassam mousa Abd-Elrahman m metwalli Walid A mawla mostafa m Elaidy muhammad Ali Baghdadi Ahmed Raafat Department of General Surgery Faculty of MedicineZagazig UniversityZagazig 44759SharkiaEgypt Homerton University Hospital London E96SRUK Department of Surgical Science University of CagliariCagliari 2432Italy Department of medical and Surgical Sciences Universitàdegli studi di FoggiaFoggia 546Italy mD CQInsights PBC Co-founder&CEOTennesseeTN 37010United States Department of Internal medicine Zagazig UniversityZagazig 2355Egypt Department of Internal medicine Suez UniversitySuez 235Egypt Department of General Surgery Faculty of Medicine-Merit UniversitySohag 82511Egypt Department of General Surgery Al-azhar UniversityCairo 285Egypt Department of Hepato-Bilio-Pancreatic(HBP)Surgery National Hepatology and Tropical Medicine Research InstituteCairo 285Egypt Department of General Surgery Mataryia Teaching HospitalCairo 285Egypt

BACKGROUND Hepatobiliary manifestations occur in ulcerative colitis(UC)*** effect of laparoscopic restorative proctocolectomy(LRP)with ileal pouch anal anastomosis(IPAA)on hepatobiliary manifestations is *** To evaluate hepatobiliary changes after two-stages elective laparoscopic restorative proctocolectomy for patients with *** Between June 2013 and June 2018,167 patients with hepatobiliary symptoms underwent two-stage elective LRP for UC in a prospective observational *** with UC and having at least one hepatobiliary manifestation who underwent LRP with IPAA were included in the *** patients were followed up for four years to assess the outcomes of hepatobiliary *** The patients'mean age was 36±8 years,and males predominated(67.1%).The most common hepatobiliary diagnostic method was liver biopsy(85.6%),followed by magnetic resonance cholangiopancreatography(63.5%),Antineutrophil cytoplasmic antibodies(62.5%),abdominal ultrasonography(35.9%),and Endoscopic retrograde cholangiopancreatography(6%).The most common hepatobiliary symptom was Primary sclerosing cholangitis(PSC)(62.3%),followed by fatty liver(16.8%)and gallbladder stone(10.2%).66.4%of patients showed a stable course after *** or regressive courses occurred in 16.8%of *** was 6%,and recurrence or progression of symptoms required surgery for 15%.most PSC patients(87.5%)had a stable course,and only 12.5%became ***-thirds(64.3%)of fatty liver patients showed a regressive course,while one-third(35.7%)showed a stable *** rates were 98.8%,97%,95.8%,and 94%at 12 mo,24 mo,36 mo,and at the end of the *** In patients with UC who had LRP,there is a positive impact on hepatobiliary *** caused an improvement in PSC and fatty liver *** most prevalent unchanged course was PSC,while the most common improvement was fatty liver disease.

关键词： Courses Hepatobiliary manifestations Primary sclerosing cholangitis Restorative proctocolectomy

models to predict injury, physical fitness failure and attrition in recruit training: a retrospective cohort study

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military medical Research 2020年第4期7卷 391-400页

作者： Robin m.Orr bruce S.Cohen Stephen C.Allison Lakmini Bulathsinhala Edward J.Zambraski mark Jaffrey Tactical Research Unit Bond University2 Promethean WayGold CoastRobinaQLD 4226Australia United States Army Research Institute for Environmental medicine NatickMA 01760USA Defence Science and Technology Group Port MelbourneVIC 3207Australia

Background:Attrition rate in new army recruits is higher than in incumbent *** the current study,we identified the risk factors for attrition due to injuries and physical fitness failure in recruit training.A variety of predictive models were ***:This retrospective cohort included 19,769 Army soldiers of the Australian Defence Force receiving recruit training during a period from 2006 to *** them,7692 reserve soldiers received a 28-day training course,and the remaining 12,077 full-time soldiers received an 80-day training *** data included anthropometric measures,course-specific variables,injury,and physical fitness *** regression was used to develop a variety of models to predict the rate of attrition due to injuries and physical fitness *** area under the receiver operating characteristic curve was used to compare the performance of the ***:In the overall analysis that included both the 28-day and 80-day courses,the incidence of injury of any type was 27.8%.The 80-day course had a higher rate of injury if calculated per course(34.3%vs.17.6%in the 28-day course),but lower number of injuries per person-year(1.56 vs.2.29).Fitness test failure rate was significantly higher in the 28-day course(30.0%vs.12.1%).The overall attrition rate was 5.2%and 5.0%in the 28-day and 80-day courses,*** fracture was common in the 80-day course(n=44)and rare in the 28-day course(n=1).The areas under the receiver operating characteristic curves for the course-specific predictive models were relatively low(ranging from 0.51 to 0.69),consistent with"failed"to"poor"predictive *** course-combined models performed somewhat better than the course-specific models,with two models having AUC of 0.70 and 0.78,which are considered"fair"predictive ***:Attrition rate was similar between 28-day and 80-day *** comparison to the 80-day full course,the 28-day course had a lower rat

关键词： military training Predictive modelling Risk management Soldier

Impacts of bovine spongiform encephalopathy and avian influenza on U.S. meat demand

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Journal of Integrative Agriculture 2015年第6期14卷 1130-1141页

作者： Jianhong E mu bruce A mcCarl Amy Hagerman David Bessler Department of Applied Economics Oregon State University Department of Agricultural Economics Texas A&M University Center for Epidemiology and Animal Health Veterinary Services Animal and Plant Health Inspection Service United States Department of Agriculture

This paper examines the U.S. meat demand impacts of the announced outbreaks of bovine spongiform encephalopathy（BSE） and avian influenza（AI）. Findings indicate that beef and chicken demand was negatively affected by BSE and AI disease outbreaks. Specifically, in the short run, U.S. consumers shift demand due to both outbreaks but more so due to domestic disease outbreaks than for outbreaks occurring overseas-the impact of U.S. AI outbreaks is about 0.5% for beef and the impact of U.S. BSE cases is around –0.42% for beef and 0.4% for pork, respectively. Regarding the BSE shock on meat demand, there is a high rate of beef demand adjusted from disturbance to the long-run equilibrium and a lower adjustment rate for chicken demand because of the repeated outbreaks of AI worldwide. In the long run, information related to severe, persistently recurring overseas animal disease outbreaks changes U.S. consumers＇ meat consumption patterns. Although effects of animal diseases on U.S. meat demand were statistically significant, the magnitudes were small-the impact of WHO reported human death numbers for AI is 0.005% for beef, –0.002% for pork, and –0.006% for chicken and the impact of U.S. BSE cases is 1.1% for pork and –0.7% for chicken.

关键词： spongiform avian chicken bovine encephalopathy overseas disturbance adjustment pathogenic deaths

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： G. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli m.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik m.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai G. Aielli A. Aikot m. Ait Tamlihat B. Aitbenchikh I. Aizenberg m. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury G.L. Alberghi J. Albert P. Albicocco G.L. Albouy S. Alderweireldt m. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi m. Algren m. Alhroob B. Ali H.m.J. Ali S. Ali S.W. Alibocus m. Aliev G. Alimonti W. Alkakhi C. Allaire B.m.m. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani m. Alvarez Estevez A. Alvarez Fernandez m. Alves Cardoso m.G. Alviggi m. Aly Y. Amaral Coutinho A. Ambler C. Amelung m. Amerl C.G. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel m.T. Anthony E. Antipov m. Antonelli F. Anulli m. Aoki T. Aoki J.A. Aparisi Pozo m.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold G. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin m. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup G. Avolio K. Axiotis G. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia m. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi Gupta V. Balakrishnan R. Balasubramanian E.m. Baldin P. Balek E. Ballabene F. Balli L.m. Baltes W.K. Balunas J. Balz E. Banas m. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak m. Barakat E.L. Barberio D. Barberis m. Barbero m.Z. Barel K.N. Barends T. Barillari m-S. Barisits T. Barklow P. Baron D.A. Baron mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced *** paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS *** taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet *** in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK GLUON TAGGING

Surface-enhanced Raman scattering nanosensors for in vivo detection of nucleic acid targets in a large animal model

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Nano Research 2018年第8期11卷 4005-4016页

作者： Hsin-Neng Wang Janna K. Register Andrew m. Fales Naveen Gandra Eugenia H. Cho Alina Boico Gregory m. Palmer bruce Klitzman Tuan Vo-Dinh Departments of Biomedical Engineering Duke University Durham NC27708 USA Fitzpatrick Institute for Photonics Duke University Durham NC27708 USA medical Center Duke University Durham NC27710 USA Deportments of Chemistry Duke University Durham NC27708 USA Hsin-Neng Wang Janna K. Register and Andrew M. Fales contributed equally to this work.

Although nanotechnology has led to important advances in in vitro diagnostics, the development of nanosensors for in vivo detection remains very challenging. Here, we demonstrated the proof-of-principle of in vivo detection of nudeic acid targets using a promising type of surface-enhanced Raman scattering （SERS） nanosensor implanted in the skin of a large animal model （pig）. The in vivo nanosensor used in this study involves the ＂inverse molecular sentinel＂ detection scheme using plasmonics-active nanostars, which have tunable absorption bands in the near infrared region of the ＂tissue optical window＂, rendering them efficient as an optical sensing platform for in vivo optical detection. Ex vivo measurements were also performed using human skin grafts to demonstrate the detection of SERS nanosensors through tissue. In this stud, a new core--shell nanorattle probe with Raman reporters trapped between the core and shell was utilized as an internal standard system for self-calibration. These results illustrate the usefulness and translational potential of the SERS nanosensor for in vivo biosensing.

关键词： nanosensor nanoprobes plasmonics nanostar surface-enhanced Ramanscattering (SERS) in vivo sensing

The effect of tailing lipidation on the bioactivity of antimicrobial peptides and their aggregation tendency Special Issue:Emerging Investigators

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聚集体(英文)

聚集体(英文) 2023年第4期4卷 195-209页

作者： bruce Lin Andrew Hung William Singleton Kevion K.Darmawan Rachael moses Bicheng Yao Hongkang Wu Anders Barlow marc-Antoine Sani Alastair J.Sloan mohammed Akhter Hossain John D.Wade Yuning Hong Neil m.O’Brien-Simpson Wenyi Li The Bio21 Institute of molecular Science and Biotechnology University of MelbourneMelbourneVictoriaAustralia ACTV Research group Melbourne Dental SchoolCentre for Oral Health ResearchUniversity of MelbourneMelbourneVictoriaAustralia School of Science RMIT UniversityMelbourneVictoriaAustralia melbourne Dental School Division of Basic and Clinical Oral SciencesUniversity of MelbourneMelbourneVictoriaAustralia Department of Biochemistry and Chemistry La Trobe Institute for Molecular ScienceLa Trobe UniversityMelbourneVictoriaAustralia Florey Institute of Neuroscience and mental Health University of MelbourneMelbourneVictoriaAustralia School of Chemistry University of MelbourneMelbourneVictoriaAustralia materials Characterisation and Fabrication Platform University of MelbourneMelbourneVictoriaAustralia

Antimicrobial peptides(AmPs)are potentially powerful alternatives to conven-tional antibiotics in combating multidrug resistance,given their broad spectrum of *** mainly interact with cell membranes through surface electrostatic potentials and the formation of secondary structures,resulting in permeability and destruction of target microorganism *** earlier work showed that two leading AmPs,mSI-78(4–20)and pardaxin(1–22),had potent antimicrobial activ-ity against a range of *** is known that the attachment of moderate-length lipid carbon chains to cationic peptides can further improve the functionality of these peptides through enhanced interactions with the membrane lipid bilayer,inducing membrane curvature,destabilization,and potential ***,in this work,we aimed to investigate the antimicrobial activity,oligomerization propensity,and lipid-membrane binding interactions of a range of N-terminal lipidated analogs of mSI-78(4–20)and pardaxin(1–22).molecular modeling results suggest that aggregation of the N-lipidated AmPs may impart greater structural stability to the peptides in solu-tion and a greater depth of lipid bilayer insertion for the N-lipidated AmPs over the parental *** experimental and computationalfindings provide insights into how N-terminal lipidation of AmPs may alter their conformations,with subsequent effects on their functional properties in regard to their self-aggregation behavior,membrane interactions,and antimicrobial activity.

关键词： aggregation antimicrobial peptide lipidation membrane active peptide

Distinguishing erosive osteoarthritis and calcium pyrophosphate deposition disease

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World Journal of Orthopedics 2013年第2期4卷 29-31页

作者： bruce m Rothschild Department of medicine Northeastern Ohio Medical University Rootstown OH 44272 United States Biodiversity Institute University of Kansas Museum of Natural History Lawrence KS 66045 United States

Erosive osteoarthritis is a term utilized to describe a specific inflammatory condition of the interphalangeal and first carpal metacarpal joints of the hands. The term has become a part of medical philosophical semantics and paradigms, but the issue is actually more complicated. Even the term osteoarthritis(nonerosive) has been controversial, with some suggesting osteoarthrosis to be more appropriate in view of the perspective that it is a non-inflammatory process undeserving of the "itis" suffix. The term "erosion" has also been a source of confusion in osteoarthritis, as it has been used to describe cartilage, not bone lesions. Inflammation in individuals with osteoarthritis actually appears to be related to complicating phenomena, such as calcium pyrophosphate and hydroxyapatite crystal deposition producing arthritis. Erosive osteoarthritis is the contentious term. It is used to describe a specific form of joint damage to specific joints. The damage has been termed erosions and the distribution of the damage is to the interphalangeal joints of the hand and first carpal metacarpal joint. Inflammation is recognized by joint redness and warmth, while X-rays reveal alteration of the articular surfaces, producing a smudged appearance. This ill-defined, joint damage has a crumbling appearance and is quite distinct from the sharply defined erosions of rheumatoid arthritis and spondyloarthropathy. The appearance is identical to those found with calcium pyrophosphate deposition disease, both in character and their unique responsiveness to hydroxychloroquine treatment. Low doses of the latter often resolve symptoms within weeks, in contrast to higher doses and the months required for response in other forms of inflammatory arthritis. Reconsidering erosive osteoarthritis as a form of calcium pyrophosphate deposition disease guides physicians to more effective therapeutic intervention.

关键词： Erosive osteoarthritis Calcium pyrophosphate deposition disease Rheumatoid arthritis Spondyloarthropathy Osteoarthritis Hydroxychloroquine

小型田鼠:研究单配制进化与调控的模型(英文)

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兽类学报 2005年第2期25卷 182-199页

作者： bruce S Cushing Kristin m Kramer The Brain Body Center Department of PsychiatryCollege of MedicineUniversity of Illinoisat ChicagoChicagoIL60612USAThe Brain Body CenterDepartment of PsychiatryCollege of MedicineUniversity of Illinoisat ChicagoChicagoIL60612USA

哺乳动物的单配制通常被认为是社会性单配制,它不是单纯地由性行为来决定,而是由诸多因素,包括长期的pairbond、夫妻双方共同抚育后代、免近亲交配以及雌雄两性相似等来决定的。在这篇综述中,我们论述了如何以啮齿类田鼠属(microtus)为... 详细信息

哺乳动物的单配制通常被认为是社会性单配制,它不是单纯地由性行为来决定,而是由诸多因素,包括长期的pairbond、夫妻双方共同抚育后代、免近亲交配以及雌雄两性相似等来决定的。在这篇综述中,我们论述了如何以啮齿类田鼠属(microtus)为模型,通过比较研究来帮助我们理解社会性单配制的进化以及其神经调控机制。对田鼠属的研究不仅证实了单配制起源于艰苦的生存条件的假说,而且还证实了雌性性选择可能有利于维持单配制。不仅如此,哺乳动物单配制的进化还需要雄性的prosocial行为的不断强化。例如,亲近行为可以促进pairbond的形成并强化雄性对后代的哺育行为,而这种强化则来源于神经多肽催产素(OT)和加压素(AVP)与类固醇类激素的相互作用。催产素和加压素调控pairbond和双亲哺育行为的表达,而单配制和多配制田鼠的催产素和加压素受体在脑内的分布有显著的不同。比较研究揭示了小型田鼠单配制的调控机制,而种内差异和行为上的可塑性则有助于我们进一步理解这种机制。比如,在某些条件下,多配制的草原田鼠(microtuspennsylvanicu)的雄性个体具有哺育后代的行为。尽管草原田鼠的加压素V1a受体在脑内的分布与其他多配制的田鼠相似,但是如果脑室注射加压素,仍可以诱发其哺育后代的行为。

关键词：单配制进化模型哺乳动物调控机制比较研究草原田鼠攻击行为加压素雌激素受体催产素 pair bond 近亲交配生存条件相互作用神经多肽种内差异脑室注射橙腹田鼠受体表达终纹床核敏感程度社会性性行为

货运车辆中途休息站地理分布问题研究(英文)

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交通运输系统工程与信息 2012年第4期12卷 93-105页

作者： SRIVASTAVA Praveen WANG bruce X ADAmS Teresa m 威斯康辛大学麦迪逊分校国家货物与基础设施研究与教育中心德州农工大学 Zachry土木工程学院

货运车辆行车途中能否有安全便利的休息站,关系到联邦关于司机工作时间规定的执行及高效的车队运营.由于货运车辆的激增,中途停车站能力短缺问题日益凸显.本研究开发了一个基于互联网的地理信息系统,用于从用户大范围收集停车位短缺的... 详细信息

货运车辆行车途中能否有安全便利的休息站,关系到联邦关于司机工作时间规定的执行及高效的车队运营.由于货运车辆的激增,中途停车站能力短缺问题日益凸显.本研究开发了一个基于互联网的地理信息系统,用于从用户大范围收集停车位短缺的地理信息.为了分析这些停车紧张点的地理分布,采用了点聚合和排名的方法来发现停车问题最严重的地区.另外,提出一种沿公路方向的单测度的聚合方法.其基本思路是,停车问题不是一个单点问题,而是一个区域性问题.缓解停车紧张,可通过增加区域性停车能力.本文发现能力紧张的区域通常在大都市的郊区,反映出很多长途司机在此停车等待第二天往市区内送货的运作规律.研究结果与来自公路巡警方面的观察结果一致.

关键词：公路运输货物移动性货运车辆停靠调查基于互联网的地理信息系统 Google地图聚类分析地理分布分析