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Look into my eyes:What can eye-based measures tell us about the relationship between physical activity and cognitive performance?

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Journal of Sport and Health Science 2023年第5期12卷 568-591页

作者： Liye Zou Fabian Herold Sebastian Ludyga Keita Kamijo Notger G.Muller Matthew B.Pontifex Matthew Heath Ryuta Kuwamizu Hideaki Soya Charles H.Hillman Soichi Ando brandon L.Alderman Boris Cheval Arthur F.Kramer Body-Brain-Mind Laboratory School of PsychologyShenzhen UniversityShenzhen 518060China Research Group Degenerative and Chronic Diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam 14476Germany Department of Sport Exerciseand HealthUniversity of BaselBasel 4052Switzerland Faculty of Liberal Arts and Sciences Chukyo UniversityNagoya 466-8666Japan Department of Kinesiology Michigan State UniversityEast LansingMI 48824USA School of Kinesiology Faculty of Health SciencesUniversity of Western OntarioLondon ON N6A 3K7Canada Canadian Centre for Activity and Aging University of Western OntarioLondon ONN6A 3K7Canada Graduate Program in Neuroscience University of Western OntarioLondon ONN6A 3K7Canada Laboratory of Exercise Biochemistry and Neuroendocrinology Faculty of Health and Sport SciencesUniversity of TsukubaTsukuba 305-0006Japan Sport Neuroscience Division Advanced Research Initiative for Human High Performance(ARIHHP)Faculty of Health and Sport SciencesUniversity of TsukubaTsukuba 305-0006Japan Center for Cognitive and Brain Health Department of PsychologyDepartment of Physical TherapyMovementand Rehabilitation SciencesNortheastern UniversityBostonMA 02115USA Graduate School of Informatics and Engineering The University of Electro-CommunicationsTokyo 182-8585Japan Department of Kinesiology and Health Rutgers UniversityNew BrunswickNew BrunswickNJ 08854USA Swiss Center for Affective Sciences University of GenevaGeneva 1205Switzerland Laboratory for the Study of Emotion Elicitation and Expression(E3Lab) Department of PsychologyUniversity of GenevaGeneva 1205Switzerland Department of Psychology Center for Cognitive and Brain HealthNortheastern UniversityBostonMA 02115USA Beckman Institute University of Illinois at Urbana-ChampaignChampaignIL 61820USA

Background:There is a growing interest to understand the neurobiological mechanisms that drive the positive associations of physical activity and fitness with measures of cognitive *** better understand those mechanisms,several studies have employed eye-based measures(e.g., eye movement measures such as saccades,pupillary measures such as pupil dilation,and vascular measures such as retinal vessel diameter)deemed to be proxies for specific neurobiological ***,there is currently no systematic review providing a comprehensive overview of these studies in the field of exercise-cognition ***,this review aimed to address that gap in the ***:To identify eligible studies,we searched 5 electronic databases on October 23,*** researchers independently extracted data and assessed the risk of bias using a modified version of the Tool for the assEssment of Study qualiTy and reporting in EXercise(TESTEX scale,for interventional studies) and the critical appraisal tool from the Joanna Briggs Institute(for cross-sectional studies).Results:Our systematic review(n=35 studies) offers the following main findings:(a) there is insufficient evidence available to draw solid conclusions concerning gaze-fixation-based measures;(b) the evidence that pupillometric measures,which are a proxy for the noradrenergic system,can explain the positive effect of acute exercise and cardiorespiratory fitness on cognitive performance is mixed;(c) physical training-or fitness-related changes of the cerebrovascular system(operationalized via changes in retinal vasculature) are,in general,positively associated with cognitive performance improvements;(d) acute and chronic physical exercises show a positive effect based on an oculomotor-based measure function(operationalized via antisaccade tasks);and(e) the positive association between cardiorespiratory fitness and cognitive performance is partly mediated by the dopaminergic system(operationalized via spo

关键词： Cognition Exercise Fitness Pupil size RetinaTagedAPTARAEnd

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Neuroinflammation and subarachnoid hemorrhage: a revised look at the literature

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Clinical Research Communications 2022年第3期5卷 13-23页

作者： Sai Sriram Christopher Cutler Mohammed Azab Ramya Reddy Rodeania Peart brandon Lucke-Wold Department of Neurosurgery University of FloridaGainesvilleFLU.S.A. Rosalind Franklin University of Medicine and Science ChicagoILU.S.A. Department of Biomolecular Sciences Boise State UniversityBoiseIDU.S.A.

A key topic for aneurysmal subarachnoid hemorrhage is *** can predispose to aneurysm formation and *** can also result from the blood breakdown products after aneurysm *** evidence has shown that perpetual neuroinflammation can contribute to vasospasm and *** neuroinflammation is a novel mechanism for preventing subsequent neurologic *** this review,we highlight the pathophysiology of aneurysm formation,the neuroinflammatory surge after rupture including the involved cytokines,and ultimately tie in the contributory clinical *** the last sections,we look at the pre-clinical data and novel avenues for further *** paper will be a useful resource to both the clinician and scientific investigator.

关键词： neuroinflammation subarachnoid hemorrhage treatment approach aneurysm formation

Mutations of the brpR and brpS genes affect biofilm formation in Staphylococcus aureus

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World Journal of Clinical Infectious Diseases 2022年第1期12卷 20-32页

作者： Allison Zank Lillian Schulte Xavier brandon Lauren Carstensen Amy Wescott William R Schwan Department of Microbiology University of Wisconsin-La CrosseLa CrosseWI 54601United States

BACKGROUND In the United States,Staphylococcus aureus(***)kills tens of thousands of individuals each year and the formation of a biofilm contributes to ***-associated infections are hard to treat once the biofilm has formed.A new stilbene drug,labeled SK-03-92,was shown to kill *** and affected transcription of two genes tied to a putative two-component system(TCS)we have named brpR(biofilm regulating protein regulator)and brpS(biofilm regulating protein sensor).AIM To determine if BrpR and BrpS regulate biofilm formation,brpR and brpS mutants were assessed using biofilm assays compared to wild-type *** A combination of biofilm and quantitative real-time-polymerase chain reaction assays were *** addition,bioinformatic software tools were also *** Significantly more biofilm was created in the brpR and brpS mutants vs wild-type *** real-time polymerase chain reactions showed the brpS mutant had differences in transcription of biofilm associated genes that were eight-fold higher for srtA,two-fold lower for lrgA,and 1.6-fold higher for cidA compared to *** analysis demonstrated that the *** brpR/brpS TCS had homology to streptococcal late-stage competence proteins involved in celldeath,increased biofilm production,and the development of persister *** Our study suggests that brpR/brpS is a TCS that may repress *** biofilm production and be linked to late-stage competence in ***.

关键词： Biofilm Two-component system Stilbene Staphylococcus aureus Late-stage competence SK-03-92

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确定杂散来源是DDS/DAC还是其他器件

中国电子商情 2023年第9期 40-41页

作者： David brandon ADI

简介直接数据频率合成器(DDS)因能产生频率捷变且残留相位噪声性能卓越而著称。另外,多数用户都很清楚DDS输出频谱中存在的杂散噪声,比如相位截断杂散以及与相位-幅度转换过程相关的杂散等。此类杂散是实际DDS设计中的有限相位和幅度分... 详细信息

简介直接数据频率合成器(DDS)因能产生频率捷变且残留相位噪声性能卓越而著称。另外,多数用户都很清楚DDS输出频谱中存在的杂散噪声,比如相位截断杂散以及与相位-幅度转换过程相关的杂散等。此类杂散是实际DDS设计中的有限相位和幅度分辨率造成的结果。

关键词：频率合成器频率捷变相位噪声输出频谱 DDS 杂散 DAC 分辨率

US-China Relations:Nationalism,the Trade War,and COVID-19

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Fudan Journal of the Humanities and Social Sciences 2021年第1期14卷 23-40页

作者： brandon M.Boylan Jerry McBeath Bo Wang University of Alaska Fairbanks(UAF) 603 C/D Gruening Building1747 South Chandalar DriveFairbanksAK 99775USA Emeritus of Political Science University of Alaska Fairbanks(UAF)1777 Red Fox DriveFairbanksAK 99709USA School of International Relations China University of International Business and Economics(UIBE)Mail Box 100No.10 Huixin East StreetChangyang DistrictBeijing 100029People’s Republic of China

The trade war between the USA and China has shocked many across the world.A disruption to the interdependence of the two largest economies seemed ***,in an effort to thwart China’s economic practices and boost the US economy,President Trump’s administration levied tariffs on Chinese imports shortly after taking office,moving US foreign economic policy from liberalism,practiced for decades,to *** has retaliated,and the trade war continues *** conceptual insights from the nationalism literature,we explore the nationalist roots of the trade war from both the US and Chinese *** the USA,the Trump administration’s plan to achieve energy autonomy,decrease reliance on foreign resources,and reinvigorate the manufacturing sector has led to protectionist policies,the othering of China,and hence the trade *** reluctant to enter the conflict,China has rebuffed the USA,resisting and counterattacking US actions,owing to a long-felt sense of persecution in the global space and an eagerness to participate fully,and lead in some issue areas,in international *** conflict continues into the COVID-19 era,marked by US scapegoating of China and hits to economic *** both sides are convinced they have achieved their goals,or the USA undergoes an administration change,the conflict will likely continue.

关键词： US-China relations Nationalism International trade Natural resources Energy Political economy COVID-19

Aerosol printing and photonic sintering of bioresorbable zinc nanoparticle ink for transient electronics manufacturing

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Science China(Information Sciences) 2018年第6期61卷 40-49页

作者： Bikram Kishore MAHAJAN brandon LUDWIG Wan SHOU Xiaowei YU Emmanuel FREGENE Hang XU Heng PAN Xian HUANG Department of Mechanical Engineering Missouri University of Science and Technology Department of Material Science and Engineering Georgia Institute of Technology Department of Biomedical Engineering Tianjin University

Bioresorbable electronics technology can potentially lead to revolutionary applications in healthcare, consumer electronics, and data security. This technology has been demonstrated by various functional devices. However, majority of these devices are realized by CMOS fabrication approaches involving complex and time-consuming processes that are high in cost and low in yield. Printing electronics technology represents a series of printing and post processing techniques that hold promise to make high performance bioresorbable electronics devices. But investigation of printing approaches for bioresorbable electronics is very limited. Here we demonstrate fabrication of conductive bioresorbable patterns using aerosol printing and photonic sintering approaches. Experimental results and simulation reveals that ink compositions, photonic energy, film thickness, and ventilation conditions may influence the effect of photonic sintering. A maximum conductivity of 22321.3 S/m can be achieved using 1 flash with energy of 25.88 J/cm~2 with duration of 2 ms. By combining two cascaded sintering procedures using flash light and laser further improve the conductivity to 34722.2 S/m. The results indicate that aerosol printing and photonic sintering can potentially yield mass fabrication of bioresorbable electronics, leading to prevalence of printable bioresorbable technology in consumer electronics and biomedical devices.

关键词： bioresorbable electronics photonic sintering aerosol printing transient electronics printed electronics zinc nanoparticles

Hydrolysis and acidification of activated sludge from a petroleum refinery

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Petroleum Science 2019年第2期16卷 428-438页

作者： Jiahao Liang Chunmao Chen brandon A.Yoza Ying Liang Jin Li Ming Ke Qinghong Wang State Key Laboratory of Heavy Oil Processing State Key Laboratory of Petroleum Pollution Control China University of PetroleumBeijing Hawaii Natural Energy Institute University of Hawaii at Manoa

The cost-effective treatment of activated sludge that is generated by refining petroleum is a challenging industrial *** this study, semi-continuous stirred tank reactors(CSTRs) containing petroleum refinery excess activated sludge(PREAS)were used to comparatively investigate hydrolysis and acidification rates, after the addition of heneicosane(C_(21)H_(44))(R1)and 1-phenylnaphthalene(C16 H12)(R2) to different and individual reactors. Operation of the reactors using a sludge retention time(SRT) of 6 days and a pH of 5.0, resulted in the maintenance of stable biological activity as determined by soluble chemical oxygen demand(SCOD), volatile fatty acids(VFAs) production and oil removal efficiency. The optimum conditions for hydrogen production include a SRT of 8 days, at pH 6.5. Under these conditions, hydrogen production rates in the control containing only PREAS were 1567 mL/L(R0), compared with 1365 mL/L in Rl and 1454 mL/L-PREAS in ***, Fervidobacterium, Caldisericum and Tepidiphilus were the dominant bacterial genera that have the potential to degrade petroleum compounds and generate VFAs. This study has shown that high concentrations of heneicosane and 1-phenylnaphthalene did not inhibit the hydrolytic acidification of PREAS.

关键词： Hydrolysis acidification Petroleum refinery excess activated sludge (PREAS) VFA production Hydrogen production Microbial community

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Structural variation and parallel evolution of apomixis in citrus during domestication and diversification

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National Science Review 2022年第10期9卷 82-97页

作者： Nan Wang Xietian Song Junli Ye Siqi Zhang Zhen Cao Chenqiao Zhu Jianbing Hu Yin Zhou Yue Huang Shuo Cao Zhongjie Liu Xiaomeng Wu Lijun Chai Wenwu Guo Qiang Xu brandon S.Gaut Anna M.G.Koltunow Yongfeng Zhou Xiuxin Deng Key Laboratory of Horticultural Plant Biology (Ministry of Education) Huazhong Agricultural University Shenzhen Branch Guangdong Laboratory of Lingnan Modern Agriculture Genome Analysis Laboratory of the Ministry of Agriculture and Rural Affairs Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences Department of Ecology and Evolutionary Biology University of California Irvine Queensland Alliance for Agriculture and Food Innovation University of Queensland

Apomixis,or asexual seed formation,is prevalent in Citrinae via a mechanism termed nucellar or adventitious ***,multiple embryos of a maternal genotype form directly from nucellar cells in the ovule and can outcompete the developing zygotic embryo as they utilize the sexually derived endosperm for *** nucellar embryony enables the propagation of clonal plants of maternal genetic constitution,it is also a barrier to effective breeding through *** address the genetics and evolution of apomixis in Citrinae,a chromosome-level genome of the Hongkong kumquat(Fortunella hindsii) was assembled following a genome-wide variation map including structural variants(SVs) based on234 Citrinae *** map revealed that hybrid citrus cultivars shelter genome-wide deleterious mutations and SVs into heterozygous states free from recessive selection,which may explain the capability of nucellar embryony in most cultivars during Citrinae *** reve aled that parallel evolution may explain the repeated origin of apomixis in different genera of *** Fortu nella,we found that apomixis of some varieties originated via *** apomictic Fortunella,the locus associated with apomixis contains the FhRWP gene,encoding an RWP-RK domain-containing protein previously shown to be required for nucellar embryogenesis in *** found the heterozygous SV in the FhRWP and CitRWP promoters from apomictic Citrus and Fortunella,due to either two or three miniature inverted transposon element(MITE) insertions.A transcription factor,FhARID,encoding an AT-rich interaction domain-containing protein binds to the MITEs in the promoter of apomictic varieties,which facilitates induction of nucellar *** study provides evolutionary genomic and molecular insights into apomixis in Citrinae and has potential ramifications for citrus breeding.

关键词： genomics evolution population genetics apomixis

High-Content Screening and Analysis of Stem Cell-Derived Neural Interfaces Using a Combinatorial Nanotechnology and Machine learning Approach

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研究(英文) 2023年第1期2022卷 153-167页

作者： letao Yang Brian M.Conley Jinho Yoon Christopher Rathnam Thanapat Pongkulapa brandon Conklin Yannan Hou Ki-Bum lee Department of Chemistry and Chemical Biology Rutgers UniversityThe State University of New JerseyPiscatawayNJ 08854USA

A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based ***,high-throughput investigation of the cell-type-specific biophysical cues associated with stem cell-derived neural interfaces continues to be a significant obstacle to *** this end,we developed a combinatorial nanoarray-based method for high-throughput investigation of neural interface micro-/nanostructures(physical cues comprising geometrical,topographical,and mechanical aspects)and the effects of these complex physical cues on stem cell fate ***,by applying a machine learning(ML)-based analytical approach to a large number of stem cell-derived neural interfaces,we comprehensively mapped stem cell adhesion,differentiation,and proliferation,which allowed for the cell-type-specific design of biomaterials for neural interfacing,including both adult and human-induced pluripotent stem cells(hiPSCs)with varying genetic *** short,we successfully demonstrated how an innovative combinatorial nanoarray and ML-based platform technology can aid with the rational design of stem cell-derived neural interfaces,potentially facilitating precision,and personalized tissue engineering applications.

关键词： overcome neural rational