Neuroinflammation and subarachnoid hemorrhage: a revised look at the literature

作     者：Sai Sriram Christopher Cutler Mohammed Azab Ramya Reddy Rodeania Peart Brandon Lucke-Wold 

作者机构：Department of NeurosurgeryUniversity of FloridaGainesvilleFLU.S.A. Rosalind Franklin University of Medicine and ScienceChicagoILU.S.A. Department of Biomolecular SciencesBoise State UniversityBoiseIDU.S.A. 

出 版 物：《Clinical Research Communications》 (临床研究通讯)

年 卷 期：2022年第5卷第3期

页      面：13-23页

学科分类：070801[理学-固体地球物理学] 07[理学] 0708[理学-地球物理学] 

主　　题：neuroinflammation subarachnoid hemorrhage treatment approach aneurysm formation 

摘      要：A key topic for aneurysmal subarachnoid hemorrhage is *** can predispose to aneurysm formation and *** can also result from the blood breakdown products after aneurysm *** evidence has shown that perpetual neuroinflammation can contribute to vasospasm and *** neuroinflammation is a novel mechanism for preventing subsequent neurologic *** this review,we highlight the pathophysiology of aneurysm formation,the neuroinflammatory surge after rupture including the involved cytokines,and ultimately tie in the contributory clinical *** the last sections,we look at the pre-clinical data and novel avenues for further *** paper will be a useful resource to both the clinician and scientific investigator.