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基于改进YOLOv7-Tiny的交通多目标检测方法

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长春理工大学学报（自然科学版） 2024年第2期47卷 75-83页

作者：许文娟李野江晟王博文长春理工大学物理学院长春130022

在复杂的多目标交通环境中存在检测种类多、背景信息繁杂、图像分辨率低不能有效检测等问题,使用常见的目标检测算法不能达到高精度的实时检测效果,因此提出一种改进YOLOv7-Tiny的交通多目标检测算法。改进算法中首先使用部分卷积——PC... 详细信息

在复杂的多目标交通环境中存在检测种类多、背景信息繁杂、图像分辨率低不能有效检测等问题,使用常见的目标检测算法不能达到高精度的实时检测效果,因此提出一种改进YOLOv7-Tiny的交通多目标检测算法。改进算法中首先使用部分卷积——PConv替换原始卷积,优化模型参数量和运行速度;其次采用轻量级算子CARAFE替换原有上采样部分的最临近插值,提升特征融合能力;最后采用EfficiCLoss替换原有损失函数,提高边界框的定位精度改善检测目标因遮挡而漏检问题。此外创建一个基于交通复杂场景的多目标数据集,在此数据集上进行实验,结果表明改进后的检测算法相较于原YOLOv7-Tiny网络的mAP提高了4.3%,检测速度提高了12.5%,参数量减少了30%,满足智慧交通实时检测的要求。

关键词：交通目标检测 YOLOv7-Tiny Faster-Net EfficiCLoss

A decouple-decomposition noise analysis model for closed-loop mode-localized tilt sensors

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Microsystems & Nanoengineering 2023年第6期9卷 297-307页

作者： Kunfeng wang XingYin Xiong Zheng wang Liangbo Ma bowen wang WuHao Yang Xiaorui Bie ZhiTian Li XuDong Zou The State Key Laboratory of Transducer Technology Aerospace Information Research InstituteChinese Academy of SciencesBeijingChina School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijingChina Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCAUSA Shangdong Key Laboratory of Low-altitude Airspace Surveillance Network Technology QiLu Aerospace Information Research InstituteJinanChina

The development of mode-localized sensors based on amplitude output metrics has attracted increasing attention in recent years due to the potential of such sensors for high sensitivity and ***-localization phenomena leverage the interaction between multiple coupled resonant modes to achieve enhanced performance,providing a promising solution to overcome the limitations of traditional sensing *** noise plays a key role in determining the resolution of mode-localized sensors,as the output metric is derived from the measured AR(amplitude ratio)within the weakly coupled resonator ***,the amplitude noise originating from the weakly coupled resonator's closed-loop circuit has not yet been fully *** paper presents a decouple-decomposition(DD)noise analysis model,which is applied to achieve high resolution in a mode-localized tilt sensor based on a weakly coupled resonator closed-loop *** DD noise model separates the weakly coupled resonators using the decoupling method considering the nonlinearity of the *** integrating the decoupled weakly coupled resonators,the model decomposes the weakly coupled resonator's closed-loop circuit into distinct paths for amplitude and phase noise *** DD noise model reveals noise effects at various circuit nodes and models the system noise in the closed-loop circuit of the weakly coupled ***/Simulink simulations verify the model's accuracy when compared to theoretical *** the optimal operating point,the mode-localized tilt sensor achieves an input-referred instability of 3.91×10^(-4°)and an input-referred AR of PSD of 2.01×10^(-4°)⁄√Hz using the closed-loop noise *** model is also applicable to other varieties of mode-localized sensors.

关键词： weakly couple overcome

Formal Verification of Data Modifications in Cloud Block Storage Based on Separation Logic

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Chinese Journal of Electronics 2024年第1期33卷 112-127页

作者： bowen ZHANG Zhao JIN Hanpin wang Yongzhi CAO Key Laboratory of High Confidence Software Technologies (MOE) School of Computer Science Peking University School of Computer and Artificial Intelligence Zhengzhou University School of Computer Science and Cyber Engineering Guangzhou University

Cloud storage is now widely used, but its reliability has always been a major concern. Cloud block storage(CBS) is a famous type of cloud storage. It has the closest architecture to the underlying storage and can provide interfaces for other types. Data modifications in CBS have potential risks such as null reference or data *** verification of these operations can improve the reliability of CBS to some extent. Although separation logic is a mainstream approach to verifying program correctness, the complex architecture of CBS creates some challenges for verifications. This paper develops a proof system based on separation logic for verifying the CBS data modifications. The proof system can represent the CBS architecture, describe the properties of the CBS system state, and specify the behavior of CBS data modifications. Using the interactive verification approach from Coq, the proof system is implemented as a verification tool. With this tool, the paper builds machine-checked proofs for the functional correctness of CBS data modifications. This work can thus analyze the reliability of cloud storage from a formal perspective.

关键词： Cloud computing Behavioral sciences Reliability Formal verification

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冻伤动物模型建立的研究现状与进展

中国临床研究 2024年第5期37卷 793-796,801页

作者：李鹏曹文亮杜文霞杨波汪国梁程一钊王博文赵玲珑兵器工业卫生研究所陕西西安710065

在寒冷地区、高原高海拔、极地环境及极端条件下,冻伤不仅引发冻伤部位红肿、疼痛,严重者还可导致坏死、截肢。建立稳定、可靠的冻伤动物模型是研究冻伤发病特点和治疗方法的基础和关键。目前国内外关于冻伤动物模型的相关研究较少,且... 详细信息

在寒冷地区、高原高海拔、极地环境及极端条件下,冻伤不仅引发冻伤部位红肿、疼痛,严重者还可导致坏死、截肢。建立稳定、可靠的冻伤动物模型是研究冻伤发病特点和治疗方法的基础和关键。目前国内外关于冻伤动物模型的相关研究较少,且单一的冻伤造模方法不能满足冻伤发病机理及临床救治研究的需求,因此有必要寻求更为全面、详细的冻伤造模方法。本文综述国内外冻伤动物造模方法、冻伤部位选择等相关研究进展,以期为冻伤相关研究提供理想的动物建模方法。

关键词：冻伤动物模型液体浸冻法喷雾法冷空气法与冷固体直接接触法冻伤部位

电极留边距离对电流冲击下ZnO电阻片通流性能和故障模式的影响

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电瓷避雷器 2024年第2期 58-64,71页

作者：付志瑶王博闻胡建平方针电网输变电设备防灾减灾国家重点实验室国网湖南省电力有限公司防灾减灾中心长沙410129

在2 ms方波冲击和4/10μs大电流冲击下测试了具有不同电极留边距离的ZnO电阻片。结果表明,电极边缘和ZnO电阻片边缘留有一定余量可使冲击下的通流性能表现更稳定、减少分散性,但过多的留边距离则会使承受冲击电流的有限面积减少,留有0.5... 详细信息

在2 ms方波冲击和4/10μs大电流冲击下测试了具有不同电极留边距离的ZnO电阻片。结果表明,电极边缘和ZnO电阻片边缘留有一定余量可使冲击下的通流性能表现更稳定、减少分散性,但过多的留边距离则会使承受冲击电流的有限面积减少,留有0.5 mm左右的电极留边距离比较合适。在电流冲击测试过程中,一些ZnO电阻片样品出现故障,包括穿孔、破裂和侧闪。观察发现冲击试验后ZnO电阻片局部微观结构的形态和组成出现变化,被认为是ZnO电阻片劣化或故障的根本原因。

关键词： ZnO电阻片故障模式通流性能电极留边距离电流冲击微观结构

鼓室成形术伴与不伴乳突切开治疗活动期单纯型慢性化脓性中耳炎的疗效分析

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临床耳鼻咽喉头颈外科杂志 2024年第7期38卷 593-597页

作者：甘月园李瑞芝王博文甘海燕胡金梅田春杰唐建文大理大学临床医学院云南大理671000 大理白族自治州人民医院耳鼻喉科成都市郫都区人民医院耳鼻咽喉科成都611730

目的:分析鼓室成形术伴与不伴乳突切开治疗活动期单纯型慢性化脓性中耳炎(chronic suppurative otitis media,CSOM)的手术疗效及安全性,探讨在活动期CSOM鼓室成形术中是否可以避免开放乳突。方法:回顾性分析55例(55耳)活动期CSOM患者的... 详细信息

目的:分析鼓室成形术伴与不伴乳突切开治疗活动期单纯型慢性化脓性中耳炎(chronic suppurative otitis media,CSOM)的手术疗效及安全性,探讨在活动期CSOM鼓室成形术中是否可以避免开放乳突。方法:回顾性分析55例(55耳)活动期CSOM患者的临床资料,根据患者乳突及上鼓室发育情况,将有条件完成完壁式乳突切开术的患者为A组(30例),行鼓室成形术联合完壁式乳突切开术。无条件完成完壁式乳突切开术的患者为B组(25例)采用去除部分盾板骨质后通畅中、上鼓室及鼓窦引流,同时完成鼓室成形术。比较2组患者术后3个月鼓膜移植成活率、手术前后的听力情况及再穿孔等并发症情况。结果:活动期CSOM患者术后整体鼓膜成活率为96.4%(53/55),其中A组为96.7%;B组为96.0%,2组患者鼓膜成活率差异无统计学意义(P>0.05)。2组患者术后平均气骨导差值(ABG)较术前均有明显缩小,但2组患者ABG增益差异无统计学意义(P>0.05)。所有患者术后均无周围性面瘫、脑脊液漏、感音神经性聋等严重不良情况。结论:显微镜下采用通畅中上鼓室、鼓窦引流后的鼓室成形术治疗CSOM可获得满意的鼓膜成活率和听力提高疗效。且减少患者的创伤,防止因磨除乳突骨质后发生乳突区皮肤凹陷等并发症,缩短手术前的等待时间。

关键词：活动期慢性中耳炎乳突切开术

LncRNAs LCETRL3 and LCETRL4 at chromosome 4q12 diminish EGFR-TKIs efficiency in NSCLC through stabilizing TDP43 and EIF2S1

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Signal Transduction and Targeted Therapy 2022年第2期7卷 583-594页

作者： Yankang Li Yue Shen Mengyu Xie bowen wang Teng wang Jiajia Zeng Hui Hua Jinming Yu Ming Yang Cheeloo College of Medicine Shandong UniversityJinanShandong Province 250112China Shandong Provincial Key Laboratory of Radiation Oncology Cancer Research CenterShandong Cancer Hospital and InstituteJinanShandong Province 250117China Shandong University Cancer Center JinanShandong Province 250117China Department of Radiation Oncology Shandong Cancer Hospital and InstituteShandong First Medical University and Shandong Academy of Medical SciencesJinanShandong Province 250117China

Epidermal growth factor receptor(EGFR)-tyrosine kinase inhibitors(TKIs)are effective targeted therapy drugs for advanced nonsmall cell lung cancer(NSCLC)patients carrying sensitized EGFR *** rapid development of EGFR-TKIs resistance represents a major clinical challenge for managing *** chromosome 4q12 is the first genome-wide association study(GWAS)-reported locus associated with progression-free survival(PFS)of NSCLC patients treated with ***,the biological significance of the noncoding transcripts at 4q12 in NSCLC remains *** the present study,we identified two 4q12 long noncoding RNAs(lncRNAs)LCETRL3 and LCETRL4 which could significantly dimmish EGFR-TKIs *** line with their oncogenic role,evidently higher LCETRL3 and LCETRL4 levels were observed in NSCLC tissues as compared with normal ***,lncRNA LCETRL3 can interact with oncoprotein TDP43 and inhibit ubiquitination and degradation of ***,lncRNA LCETRL4 can bind and stabilize oncoprotein EIF2S1 through reducing ubiquitin-proteasome degradation of *** particular,elevated levels of LCETRL3 or LCETRL4 in NSCLC cells resulted in stabilization of TDP43 or EIF2S1,increased levels of NOTCH1 or phosphorylated PDK1,activated AKT signaling and,thus,EGFR-TKIs *** together,our data revealed a novel model that integrates two lncRNAs transcribed from the 4q12 locus into the regulation of EGFR-TKIs resistance in *** findings shed new light on the importance of functionally annotating lncRNAs in the GWAS loci and provided insights to declare novel druggable targets,i.e.,lncRNAs,which may unlock the therapeutic potential of EGFR-TKIs resistant NSCLC in the clinic.

关键词： NSCLC elevated drugs

基于非靶向代谢组学技术解析老白干白酒发酵过程中的代谢物特征

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食品科学技术学报 2024年第4期42卷 45-60页

作者：耿晓杰陈尔豹马志莹王新磊王柏文郑福平孙金沅张煜行李泽霞北京工商大学中国轻工业酿酒分子工程重点实验室/食品质量与安全北京实验室/中国轻工业酒类品质与安全重点实验室北京100048 河北衡水老白干酒业股份有限公司河北衡水053000

白酒发酵过程中的代谢物与其独特的风格特征息息相关。对于老白干白酒而言,其发酵过程中代谢物的特征及其变化规律尚未被完全解析。采用超高效液相色谱-串联质谱联用技术,对老白干白酒发酵过程中的酒醅代谢物进行了鉴定,通过主成分分析... 详细信息

白酒发酵过程中的代谢物与其独特的风格特征息息相关。对于老白干白酒而言,其发酵过程中代谢物的特征及其变化规律尚未被完全解析。采用超高效液相色谱-串联质谱联用技术,对老白干白酒发酵过程中的酒醅代谢物进行了鉴定,通过主成分分析和显著性差异分析,筛选出了差异代谢物,并通过KEGG数据库注释分析,揭示了这些差异代谢物可能参与的代谢途径。结果表明,在9个不同发酵时间点的酒醅样品中,共检测到2157种代谢物,其中172种为极显著差异代谢物(VIP>2,P0.1)。在不同发酵阶段,各类代谢物的表达量有所不同。在发酵前期(0~8 d)差异代谢物最多,共128种极显著差异代谢物(P<0.01),氨基酸、肽及其类似物,脂类,杂环类和碳水化合物及其结合物代谢显著上调;发酵中期(8~17 d)有22种代谢物有极显著差异代谢物(P<0.01),氨基酸、肽及其类似物(8~14 d)代谢显著上调,脂类代谢先上调后下调,黄酮类与之相反;发酵后期(17~36 d)有33种极显著差异代谢物(P<0.01),氨基酸、肽及其类似物和脂类代谢先上调后下调。此外,通过KEGG数据库注释,确定了104条代谢途径,并据此绘制了代谢网络图。在发酵的不同阶段,某些代谢途径变得更为活跃,如碳水化合物代谢、脂类代谢、黄酮类代谢和氨基酸代谢主要发生在发酵前期(P<0.05),而黄酮类代谢在发酵中期较为活跃(P<0.05),脂类代谢和氨基酸代谢则在发酵后期较为旺盛(P<0.05)。丝氨酸、谷氨酰胺和天冬氨酸半醛等18种代谢物在多个发酵时间段表现出显著差异,它们注释到半乳糖代谢,甘氨酸、丝氨酸和苏氨酸代谢,精氨酸和脯氨酸代谢,苯丙氨酸、酪氨酸和色氨酸生物合成及甘油磷脂代谢等途径,这可能是风味化合物的潜在生成途径。研究基于代谢组学技术,揭示了老白干白酒发酵过程中代谢物的特征及其变化规律,可为解析老白干白酒发酵过程中的风味代谢机制提供理论依据。

关键词：老白干风味化合物酒醅代谢组学代谢途径

A general descriptor for guiding the electrolysis of CO_(2)in molten carbonate

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Green Energy & Environment 2024年第4期9卷 748-757页

作者： Zhengshan Yang bowen Deng Kaifa Du Huayi Yin Dihua wang School of Resource and Environmental Sciences Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and EnergyWuhan UniversityWuhan430072China

Molten carbonate is an excellent electrolyte for the electrochemical reduction of CO_(2)to carbonaceous ***,the electrolyte–electrode-reaction relationship has not been well ***,we propose a general descriptor,the CO_(2)activity,to reveal the electrolyte–electrode-reaction relationship by thermodynamic calculations and experimental *** studies agree well with theoretical predictions that both cations(Li^(+),Ca^(2+),Sr^(2+)and Ba^(2+))and anions(BO_(2)^(-),Ti_(5)O_(14)^(8-),SiO_(3)^(2-))can modulate the CO_(2)activity to control both cathode and anode reactions in a typical molten carbonate electrolyzer in terms of tuning reaction products and *** this regard,the reduction of CO_(3)^(2-)can be interpreted as the direct reduction of CO_(2)generated from the dissociated CO_(3)^(2-),and the CO_(2)activity can be used as a general descriptor to predict the electrode reaction in molten ***,the CO_(2)activity descriptor unlocks the electrolyte–electrode-reaction relationship,thereby providing fundamental insights into guiding molten carbonate CO_(2)electrolysis.

关键词： Molten carbonate CO_(2)activity CO_(2)RR Electrolyte engineering Carbon