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至善、因袭与实用:科研诚信案件查处规范制定的价值准则

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科学与社会 2020年第4期10卷 85-101页

作者：印波北京师范大学法学院

科研诚信案件调查处理规范一般由不同学科背景的体制内外的主体共同参与制定。以极化视角观之,科技哲学、伦理学、政策学等领域学者以及科技专家是道德引领者,关注国际科研诚信前沿做法,冀望于道德宣传、教育及科学戒律,引导相关主体树... 详细信息

科研诚信案件调查处理规范一般由不同学科背景的体制内外的主体共同参与制定。以极化视角观之,科技哲学、伦理学、政策学等领域学者以及科技专家是道德引领者,关注国际科研诚信前沿做法,冀望于道德宣传、教育及科学戒律,引导相关主体树立实事求是、为民造福、规范严谨的科研观。至善是其主要价值准则,自然法学是其主要立法哲学。法学学者和法律实践工作者是既有规范的坚守者,习惯于遵循上位阶规范,通过合法规则规制相关主体的行为。因袭法定规则与秩序是其优位价值判断,分析实证主义是其主要立法哲学。科研诚信管理者是拟定规范的实际适用者,有着丰富的科研失信行为查处经验,热衷于趋利避害的实际操作,通过限定主体职责,设定可行的控制与应对措施,对相关主体开展有效监管,注重规范的实用性。现实主义是其主要立法哲学。应当统合兼顾至善、因袭与实用的价值准则,制定具有整体性品质的科研诚信案件调查处理规范。

关键词：科研诚信案件调查处理规范科研失信行为价值准则

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人民币汇率弹性与全球经常账户再平衡

南方金融 2013年第1期 18-27页

作者：殷波浙江工商大学金融学院浙江杭州310018

当前我国正在稳步推进人民币汇率形成机制改革,逐步增强人民币汇率弹性,让市场在汇率形成中发挥越来越大的作用。本文运用多国面板VAR模型系数因子化的方法,研究人民币汇率弹性对全球经常账户失衡的影响。研究结果表明:增强人民币汇率... 详细信息

当前我国正在稳步推进人民币汇率形成机制改革,逐步增强人民币汇率弹性,让市场在汇率形成中发挥越来越大的作用。本文运用多国面板VAR模型系数因子化的方法,研究人民币汇率弹性对全球经常账户失衡的影响。研究结果表明:增强人民币汇率弹性不能显著改善全球经常账户失衡,而中国经济增长对改善全球经常账户失衡有积极的贡献,因此发达国家特别是美国经常账户赤字的调整不应以牺牲中国经济增长为代价,人民币汇率形成机制的改革和汇率弹性的增强也应以不牺牲中国经济增长为底线。

关键词：人民币汇率汇率弹性经常账户失衡多国面板VAR模型系数因子化

Single-cell transcriptomic analysis identifies a highly replicating Cd168+ þskeletal stem/progenitor cell population in mouse long bones

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Journal of Genetics and Genomics 2023年第9期50卷 702-712页

作者： Rui-Cong Hao Zhi-Ling Li Fei-Yan Wang Jie Tang Pei-Lin Li bo-Feng yin Xiao-Tong Li Meng-Yue Han Ning Mao Bing Liu Li Ding Heng Zhu Basic Medical College of Anhui Medical University HefeiAnhui 230032China Beijing Institute of Radiation Medicine Beijing 100850China Beijing Institute of Basic Medical Sciences Beijing 100850China State Key Laboratory of Experimental Hematology Department of HematologyFifth Medical Center of Chinese PLA General HospitalBeijing 100071China Air Force Medical Center PLABeijing 100142China

Skeletal stem/progenitor cells(SSPCs)are tissue-specific stem/progenitor cells localized within skeletons and contribute to bone development,homeostasis,and ***,the heterogeneity of SSPC populations in mouse long bones and their respective regenerative capacity remain to be further *** this study,we perform integrated analysis using single-cell RNA sequencing(scRNA-seq)datasets of mouse hindlimb buds,postnatal long bones,and fractured long *** analyses reveal the heterogeneity of osteochondrogenic lineage cells and recapitulate the developmental trajectories during mouse long bone *** addition,we identify a novel Cd168þSSPC population with highly replicating capacity and osteochondrogenic potential in embryonic and postnatal long ***,the Cd168þSSPCs can contribute to newly formed skeletal tissues during fracture ***,the results of multicolor immunofluorescence show that Cd168þSSPCs reside in the superficial zone of articular cartilage as well as in growth plates of postnatal mouse long *** summary,we identify a novel Cd168þSSPC population with regenerative potential in mouse long bones,which adds to the knowledge of the tissuespecific stem cells in skeletons.

关键词： Skeletal stem cell scRNA-seq bone development Fracture healing bone regeneration Development

Growth and structural characteristics of metastableβ-In2Se3 thin films on H-terminated Si(111)substrates by molecular beam epitaxy

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Chinese Physics B 2020年第5期29卷 429-434页

作者： Yi-Fan Shen Xi-bo yin Chao-Fan Xu Jing He Jun-Ye Li Han-Dong Li Xiao-Hong Zhu Xiao-Bin Niu College of Materials Science and Engineering Sichuan UniversityChengdu 610064China School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu 610054China

Epitaxial growth and structural characteristics of metastableβ-In2Se3 thin films on H-terminated Si(111)substrates are *** In2Se3 thin films grown below theβ-to-αphase transition temperature(453 K)are characterized to be strainedβ-In2Se3 mixed with significantγ-In2Se3 *** pure-phased single-crystallineβ-In2Se3 can be reproducibly achieved by in situ annealing the as-deposited poly-crystalline In2Se3 within the phase equilibrium temperature window ofβ-*** is suggeted that the observedγ-to-βphase transition triggered by quite a low annealing temperature should be a rather lowered phase transition barrier of the epitaxy-stabilized In2Se3 thin-film system at a state far from thermodynamic equilibrium.

关键词： In2Se3 molecular beam epitaxy single-crystalline annealing and quench phase transition

Adaptability Analysis of IP Routing Protocol in Broadband LEO Constellation Systems

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ZTE Communications 2020年第4期18卷 34-44页

作者： SUN Chenhua yin bo LI Xudong TIAN Xing PANG Ce The 54th Research Institute of China Electronics Technology Group Corporation Shijiazhuang 050081China

With the inclusion of satellite Internet as the information infrastructure in China's "new infrastructure" category,relevant domestic industries and scientific research institutes have successively carried out the design of broadband low earth orbit(LEO) constellation systems and key technical *** the core technology for the satellite-to-ground network communications of a broadband LEO constellation system,routing technology is extremely important for the efficient and reliable transmission of various service *** on the two important broadband LEO constellation systems in China,in-depth analysis and simulation of the high dynamics of the satellite-to-ground satellites are conducted in this paper to obtain more accurate network topology changes and characteristics;then the adaptability of the ground standard IP routing protocol to the broadband LEO constellation system is analyzed,and an LEO constellation simulation scenario is built with the Opnet *** simulation results of the convergence performance of the standard IP routing protocol are *** results show that the IP protocol does not perform well for LEO satellite constellation *** on the studies,some solutions are proposed to take full advantages of the characteristics of LEO satellite *** can also provide a reference for the choice of intersatellite routing architecture and protocol technology for broadband LEO constellation in the future development.

关键词： satellite Internet IP routing protocol high dynamic networking

A Novel E-Nose Chamber Design for VOCs Detection in Automobiles

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A Novel E-Nose Chamber Design for VOCs Detection in Automobi...

Development of a humanized HLA-A30 transgenic mouse model

第三十九届中国控制会议

作者： Lu Cheng yin-bo Liu Qing-Hao Meng Institute of Robotics and Autonomous Systems Tianjin Key Laboratory of Process Measurement and ControlSchool of Electrical and Information EngineeringTianjin University

To detect parts per billion（ppb）-level volatile organic compounds（VOCs） in automobiles, a pre-concentrator is generally needed for electronic noses（e-noses）, which can enrich ppb-level concentration to parts per million（ppm） level. However, the current e-nose chamber structure could dilute the pre-concentrated gases and then the detection performance is reduced. To solve this problem, a novel chamber design was proposed in this paper. The core design idea was to reduce the space for the gas flow in the chamber, taking into account the shape and size of the gas sensors. Specially, for the pin-type gas sensors, a series of cylindrical structure design was adopted, and for the micro-electro-mechanical system（MEMS） patch-type sensors, the headspace was compressed. The results of computational fluid dynamics（CFD） based simulation showed that the concentration of pre-concentrated gases in the novel chamber was higher than that of the traditional chamber. The designed chambers were manufactured using polylactic acid（PLA） material by 3D printing. Experimental gases were prepared from polyurethane（PU） leather and polyvinyl chloride（PVC） leather to verify the performance of the chambers, and the results demonstrated that the proposed new e-nose chamber was superior to the traditional one in terms of the pre-concentration effect, repeatability and classification performance.

关键词： e-nose chamber pre-concentrator parts per billion(ppb) volatile organic compounds(VOCs) repeatability classification

来源： cnki会议评论

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Animal Models and Experimental Medicine 2022年第4期5卷 350-361页

作者： Meng-min Zhu bo-wen Niu Ling-ling Liu Hua Yang bo-yin Qin Xiu-hua Peng Li-xiang Chen Yang Liu Chao Wang Xiao-nan Ren Chun-hua Xu Xiao-hui Zhou Feng Li Department of Laboratory Animal Science Shanghai Public Health Clinical CenterShanghaiChina

Background:There are remarkable genetic differences between animal major histocompatibility complex(MHC)systems and the human leukocyte antigen(HLA)*** transgenic humanized mouse model systems offer a much better method to study the HLA-A-related principal mechanisms for vaccine development and HLA-Arestricted responses against infection in ***:A recombinant gene encoding the chimeric HLA-A30 monochain was *** HHD molecule contains the following:α1-α2 domains of HLA-A30,α3 and cytoplasmic domains of H-2D~b,linked at its N-terminus to the C-terminus of humanβ2m by a 15-amino-acid peptide *** recombinant gene encoding the chimeric HLA-A30 monochain cassette was introduced into bacterial artificial chromosome(BAC)CH502-67J3 containing the HLA-A01 gene locus by Red-mediated homologous *** BAC CH502-67J3 was microinjected into the pronuclei of wild-type mouse *** humanized mouse model was further used to assess the immune responses against influenza A virus(H1N1)pdm09 clinically isolated from human *** cell population,cytokine production,and histopathology in the lung were ***:We describe a novel humanβ2m-HLA-A30(α1α2)-H-2D~b(α3 transmembrane cytoplasmic)(HHD)monochain transgenic mouse strain,which contains the intact HLA-A01 gene locus including 49 kb 5’-UTR and 74 kb 3’-UTR of HLA-A01**** transgenic lines integrated into the large genomic region of HLA-A gene locus were obtained,and the robust expression of exogenous transgene was detected in various tissues from A30-18#and A30-19#lines encompassing the intact flanking *** cytometry revealed that the introduction of a large genomic region in HLA-A gene locus can influence the immune cell constitution in humanized ***09 infection caused a similar immune response among HLA-A30 Tg humanized mice and wild-type mice,and induced the rapid increase of cytokines,including IFN-γ,TNF-α,and IL-6,in both HLA-A30 humanized

关键词： HLA-A30 humanized mouse immunology major histocompatibility complex(MHC)

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碳化钨合金磨削仿真与工艺优化方法

红外与激光工程 2023年第7期52卷 276-285页

作者：殷博薛常喜李闯长春理工大学光电工程学院吉林长春130022 长春理工大学先进光学设计与制造技术吉林省高校重点实验室吉林长春130022

碳化钨合金因其具有高硬度、高耐磨性和高化学稳定性等优点,成为精密玻璃模压模具材料的首选。为了提高碳化钨合金模芯超精密磨削加工的表面质量,基于WC-6%Co碳化钨合金的物理特性,利用Abaqus建立磨削工艺仿真模型,分析了磨削深度、进... 详细信息

碳化钨合金因其具有高硬度、高耐磨性和高化学稳定性等优点,成为精密玻璃模压模具材料的首选。为了提高碳化钨合金模芯超精密磨削加工的表面质量,基于WC-6%Co碳化钨合金的物理特性,利用Abaqus建立磨削工艺仿真模型,分析了磨削深度、进给速度、砂轮转速及工件转速对WC-6%Co碳化钨合金磨削加工后表面粗糙度的影响规律,并讨论了磨削碳化钨合金的合理工艺参数范围。采用Taguchi法开展优化实验研究,确定出磨削碳化钨合金的最优工艺方案,在该方案指导下,完成了碳化钨合金的非球面模芯超精密磨削实验。最终得到的碳化钨合金模芯的表面粗糙度平均值为3.379 nm,验证了优化方案的有效性。

关键词：超精密磨削表面粗糙度工艺优化有限元仿真碳化钨合金

Retroperitoneal hemangiopericytoma： case report and literature review

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Chinese Medical Journal 2011年第1期124卷 155-156页

作者： yin bo LIU Li LI Ya-di GENG Dao-ying DU Zun-guo Department of Radiology Huashan Hosptial Fudan University Shanghai 200040 China Department of Pathology Huashan Hosptial Fudan-UniversityShanghai 200040 China

Retroperitoneal hemangiopericytoma is a kind of uncommon tumor. We report a case of 41-year-old man who was diagnosed retroperitoneal tumor without significant symptoms by abdominal ultrasonography. Abdominal CT and MRI scans show a 6 cmx 5 cm solid tumor delineated clearly from adjacent organs. Excision of the tumor was performed and the histopatholoCliCal examination confirmed the diaanosis of hemanoionericvtorna.

关键词： retroperitoneum hemangiopericytoma