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Progress of Sintering Technology in Handan Iron and Steel Company

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Journal of Iron and Steel Research International 2004年第5期11卷 1-7页

作者： LIU Zheng-ping WANG Yi-fang WU jin-bo Handan Iron and Steel Group Co Ltd

As one of the biggest iron and steel companies in China, Handan Iron and Steel Co has made a substantial progress in the sintering process. The mini-pellet sintering technology has been successfully applied based on lab investigation and industrial trials. Equipment enlargement was realized through replacing small sintering strands with the construction of huge sintering machine with a grate area of 400 m 2. The productivity, iron content and the metallurgical properties of sintering process have been improved.

关键词： sintering process mini-pellet sintering

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Leakage and Stiffness Characteristics of Bionic Cluster Spiral Groove Dry Gas Seal

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Chinese Journal of Mechanical Engineering 2018年第2期31卷 148-158页

作者： jin-bo Jiang Xu-Dong Peng Ji-Yun Li Yuan Chen Engineering Research Center of Process Equipment and Its Re-manufacturing of Ministry of Education Zhejiang University of Technology

Spiral groove dry gas seal(S?DGS), the most widely used DGS in the world, encounters the problem of high leakage rate and inferior film stability when used in high?speed machinery equipment, which could not be well solved by optimization of geometrical parameters and molded line of spiral groove. A new type of bionic cluster spiral groove DGS(CS?DGS) is proved to have superior film stability than S?DGS at the condition of high?speed and low?pressure numerically. A bionic CS?DGS is experimentally investigated and compared with common S?DGS in order to provide evidence for theoretical study. The film thickness and leakage rate of both bionic spiral groove and common spiral groove DGS are measured and compared with each other and with theoretical values under different closing force at the condition of static pressure, high?speed and low?pressure, and the film stiffness and stiffness?leakage ratio of these two face seals are derived by the relationship between closing force and film thickness at the steady state. Experimental results agree well with the theory that the leakage and stiffness of bionic CS?DGS are superior to that of common S?DGS under the condition of high?speed and low?pressure, with the decreasing amplitude of 20% to 40% and the growth amplitude of 20%, respectively. The opening performance and stiffness characteristics of bionic CS?DGS are inferior to that of common S?DGS when rotation speed equals to 0 r/min. The proposed research provides a new method to measure the axis film stiffness of DGS, and validates the superior performance of bionic CS?DGS at the condition of high?speed and low?pressure experimentally.

关键词： Bionic cluster spiral groove Film stiffness Dry gas seal Leakage rate

Synthesis,crystallographic characterization,and potential application of fullerene anisole derivatives as nitrocellulose stabilizer

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Defence Technology（防务技术） 2023年第6期24卷 164-172页

作者： Jie Xiong bo jin Xue-mei Yu Ling Liao Ru-fang Peng State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologySichuanMianyang621010China

A series of fullerene anisole derivative stabilizers was synthesized by nucleophilic substitution reaction using hexachlorofullerene and benzyl alcohol as raw materials to extend the service duration of nitrocellulose(NC)-based ***-crystal X-ray diffraction,nuclear magnetic resonance,highresolution mass spectrometry,Fourier transform infrared(FT-IR)spectroscopy,and UV-Vis spectroscopy were used to characterize the structures of the synthesized fullerene anisole derivative *** violet,differential scanning calorimetry test,isothermal weight loss,vacuum stability test,and adiabatic accelerated test were used to study their compatibility with NC and their ability to stabilize *** results show that the designed and synthesized novel fullerene anisole derivative stabilizer has good compatibility with NC,and their overall stabilizing effects on NC are better than those of the traditional stabilizers,diphenylamine(DPA),and N,N’-dimethyl-N,N’-diphenylurea(C2).The stabilizing effects was ranked as:3b>2d>2a>2c>C2>2b>DPA>*** addition,FT-IR analysis and electron spin resonance spectroscopy were applied to explore the stability mechanism of fullerene-based stabilizers to *** results reveal that the new fullerene stabilizer can adsorb and effectively eliminate the nitrogen oxide free radicals generated by NC degradation;therefore,it can forbid the autocatalytic degradation of NC and stabilize NC.

关键词： Fullerene Nitrocellulose Stability Propellant Mechanism

Rare-earth,nitrogen-rich,oxygen heterocyclic supramolecular compounds(Nd,Sm,and Eu):Synthesis,structure,and catalysis for ammonium perchlorate

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Journal of Rare Earths 2022年第3期40卷 428-433,I0003页

作者： Wenjia Hao Tao Huang bo jin jinhao Zhang Juan Shen Rufang Peng State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologyMianyang 621010China

Three novel rare-earth,nitrogen-rich and oxygen heterocyclic supramolecular complexes,namely[Nd(BTF)_(2)(H_(2)O)_(5)]_(n),[Sm(BTF)_(2)(H_(2)O)_(5)]_(n),and[Eu(BTF)_(2)(H_(2)O)_(5)]_(n),were synthesized.A single crystal was obtained by the solvent evaporation method,and the structure and coordination mode of metal complexes were determined by single crystal X-ray *** show that the supramolecular complexes contain many hydrogen bonds and thus have good thermal stability(T_(dec)>540 K).The thermal decomposition of ammonium perchlorate(AP)catalyzed by the complexes was investigated by differential thermal analysis,which reveals a pre-eminent catalytic effect on *** high temperature decomposition peak of AP can be advanced by nearly 90 K at the amount of added complexes of 10 wt%,and the activation energy of AP descent range is from 70 to 150 kJ/*** other properties were fully characterized through elemental analysis and Fourier transform infrared spectroscopy.

关键词： Nitrogen rich oxygen heterocycles Lanthanide supramolecular complexes Ammonium perchlorate Thermal decomposition Rare earths

Molecular mechanisms of chemoresistance in gastric cancer

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World Journal of Gastrointestinal Oncology 2016年第9期8卷 673-681页

作者： Wen-Jia Shi jin-bo Gao Department of Pediatric Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and Technology Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and Technology

Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths *** is one of the major treatments for gastric cancer,but drug resistance limits the effectiveness of chemotherapy,which results in treatment *** to chemotherapy can be present intrinsically before the administration of chemotherapy or it can develop during *** mechanisms of chemotherapy resistance in gastric cancer are complex and multifactorial.A variety of factors have been demonstrated to be involved in chemoresistance,including the reduced intracellular concentrations of drugs,alterations in drug targets,the dysregulation of cell survival and death signaling pathways,and interactions between cancer cells and the tumor *** review focuses on the molecular mechanisms of chemoresistance in gastric cancer and on recent studies that have sought to overcome the underlying mechanisms of chemoresistance.

关键词： Drug resistance Gastric cancer Chemotherapy

Characterization of the Purified Glutathione S-transferases from Two Psocids Liposcelis bostrychophila and ***

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Agricultural Sciences in China 2010年第7期9卷 1008-1016页

作者： DOU Wei XIAO Li-sha NIU jin-zhi JIANG Hong-bo WANG jin-jun Key Laboratory of Entomology and Pest Control Engineering College of Plant Protection Southwest University Chongqing 400716 P.R. China

Glutathione S-transferases（GSTs） from Liposcelis bostrychophila Badonnel and ***（Enderlein）（Psocoptera：Liposcelididae） were purified by glutathione-agarose affinity chromatography,and characterized subsequently by their Michaelis-Menten kinetics toward the artificial substrates 1-chloro-2,4-dinitrobenzene（CDNB） and reduced glutathione（GSH）,*** specific activity of the purified GST toward CDNB was 2.3-fold higher in *** than in *** the specific activities of purified enzymes varied between the two species,the purification yields were ***-PAGE revealed one band at 23 kDa for both the *** of *** exhibited higher Michaelis-Menten constants（Km） but lower maximal velocity（Vmax） values than those of *** optimum pH for CDNB conjugation of *** and *** GSTs was 7.0 and 7.5,and optimum temperature was 35 and 40°C,*** kinetics showed that cibacron blue,curcumin,bromosulfalein,ethacrynic acid,and carbosulfan had excellent inhibitory effects on GSTs in both species,but the inhibitory effects of beta-cypermethrin,fenpropathrin,tetraethylthiuram disulfide,and diethyl maleate were not significant.

关键词： GSTs purification psocids xenobiotic compounds

Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway

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World Journal of Stem Cells 2024年第5期16卷 591-603页

作者： jin-bo Wang Ming-Wei Du Yan Zheng Internal Medicine of Traditional Chinese Medicine Tongde Hospital of Zhejiang ProvinceHangzhou 310012Zhejiang ProvinceChina Institute of Cardiovascular Disease Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Shanghai Key Laboratory of Molecular Medical Mycology Second Affiliated Hospital of Naval Medical UniversityShanghai 200003China Shanghai Key Laboratory of Traditional Chinese Clinical Medicine Shanghai 201203China Department of Hepatic The Xixi Hospital of Hangzhou Affiliated to Zhejiang University of Traditional Chinese MedicineHangzhou 310023Zhejiang ProvinceChina

BACKGROUND Aplastic anemia(AA)presents a significant clinical challenge as a life-threatening condition due to failure to produce essential blood cells,with the current the-rapeutic options being notably *** To assess the therapeutic potential of ginsenoside Rg1 on AA,specifically its protective effects,while elucidating the mechanism at *** We employed a model of myelosuppression induced by cyclophosphamide(CTX)in C57 mice,followed by administration of ginsenoside Rg1 over 13 *** invest-igation included examining the bone marrow,thymus and spleen for pathological changes via hematoxylin-eosin ***,orbital blood of mice was collected for blood routine *** cytometry was employed to identify the impact of ginsenoside Rg1 on cell apoptosis and cycle in the bone marrow of AA ***,the study further evaluated cytokine levels with enzyme-linked immunosorbent assay and analyzed the expression of key proteins in the MAPK signaling pathway via western *** Administration of CTX led to significant damage to the bone marrow’s structural integrity and a reduction in hematopoietic cells,establishing a model of *** Rg1 successfully reversed hematopoietic dysfunction in AA *** comparison to the AA group,ginsenoside Rg1 provided relief by reducing the induction of cell apoptosis and inflammation factors caused by ***,it helped alleviate the blockade in the cell *** with ginsenoside Rg1 significantly alleviated myelosuppression in mice by inhibiting the MAPK signaling *** This study suggested that ginsenoside Rg1 addresses AA by alleviating myelosuppression,primarily through modulating the MAPK signaling pathway,which paves the way for a novel therapeutic strategy in treating AA,highlighting the potential of ginsenoside Rg1 as a beneficial intervention.

关键词： Aplastic anemia Ginsenoside Rg1 Myelosuppression MAPK signaling pathway bone marrow Hematopoietic stem cells

Signal Analysis by New Mother Wavelets

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Communications in Theoretical Physics 2009年第6期51卷 1010-1012页

作者： NIU jin-bo FAN Hong-Yi QI Kai-Guo Department of Physics University of Science and Technology of China Hefei 230026 China Department of Material Science and Engineering University of Science and Technology of China Hefei 230026 China

Based on the general formula for finding qualified mother wavelets [Opt. Lett. 31 （2006） 407] we make wavelet transforms computed with the newly found mother wavelets （characteristic of the power 2n） for some optical Gaussian pulses, which exhibit the ability to measure frequency of the pulse more precisely and clearly. We also work with complex mother wavelets composed of new real mother wavelets, which offer the ability of obtaining phase information of the pulse as well as amplitude information. The analogy between the behavior of Hermite Gauss beams and that of new wavelet transforms is noticed.

关键词： mother wavelet complex Mexican Hermit-Gauss

A Temporal–Spatial Atlas of Peripheral Nerve Evoked Cortex Potential in Rat:A Novel Testbed to Explore the Responding Patterns of the Brain to Peripheral Nerves

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Engineering 2022年第7期8卷 147-155页

作者： Xiaofeng Yin Jiuxu Deng bo Chen bo jin Xinyi Gu Zhidan Qi Kunpeng Leng Baoguo Jiang Department of Trauma and Orthopedics Peking University People’s HospitalBeijing 100044China

Observing the dynamic progress of the brain in response to peripheral nerve stimulation as a whole is the basis for a deeper understanding of overall brain function;however,it remains a great *** this work,a novel mini-invasive orthogonal recording method is developed to observe the overall evoked cortex potential(ECP)in rat brain.A typical ECP atlas with recognizable waveforms in the rat cortex corresponding to the median,ulnar,and radial nerve trunks and subdivided branches is *** exciting temporal–spatial progress in the rat brain is obtained and visualized for the first *** in the ECPs and exciting sequences in the cortex four months after median nerve transection are also *** results suggest that the brain’s response to peripheral stimulation has precise and reproducible temporal–spatial *** resource can serve as a testbed to explore the overall functional interaction and dynamic remodeling mechanisms between the peripheral and central nervous systems over time.

关键词： Peripheral nerve Brain Evoked cortex potential Temporal–spatial Atlas