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Effectiveness and Safety of Chinese Medicine at Shenque(CV 8)for Primary Dysmenorrhea:A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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Chinese Journal of Integrative Medicine 2023年第4期29卷 341-352页

作者： YAN li-jiao FANG Min zhu Si-jia WANG zhi-jie HU Xiao-yang liang Shi-bing WANG Dou yang Dan SHEN Chen Nicola Robinson liU Jian-ping Centre for Evidence-Based Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China Department of Oncology Shanxi Provincial Hospital of Traditional Chinese MedicineTaiyuan 030012China Primary Care and Population Sciences Faculty of MedicineUniversity of SouthamptonSO165STUnited Kingdom Research Design Service South Central National Institute of Health ResearchSouthamptonSO166YDUnited Kingdom Department of Nursing Beijing Friendship HospitalBeijing 100050China School of Nursing Beijing University of Chinese MedicineBeijing 100029China Institute of Health and Social Care London South Bank UniversityLondonSE10AAUnited Kingdom

Background:Primary dysmenorrhea(PD)is the most common complaint associated with menstruation and affects up to three-quarters of women at some stage of their reproductive *** Chinese medicine,navel therapy,treatment provided at Shenque(CV 8),is used as a treatment option for ***:To evaluate the effect of navel therapy on pain relief and quality of life in women with PD,compared with Western medicine(WM).Methods:China National Knowledge Infrastructure(CNKI),Chinese Scientific Journal Database(VIP),Sino Med and Wanfang Database,MEDliNE,the Cochrane library,Embase,Web of Science,and the International Clinical Trial Registry of the *** Institutes of Health were searched from their inceptions to April 1,*** controlled trials(RCTs)assessing therapeutic effects of navel therapy on PD were eligible for *** Man 5.4 software was used for data *** certainty of the evidence was assessed using the online GRADEpro ***:Totally 24 RCTs involving 2,614 participants were *** applied to acupuncture point CV 8 included:herbal patching,moxibustion or combined navel therapy(using at least 2 types of stimulation).Compared to placebo,there was a significant effect in favor of navel therapy on reducing overall menstrual symptom scores at the end of treatment[mean difference:-0.82,95%confidence interval(CI):-1.00 to-0.64,n=90;1 RCT].As compared with Western medicine,navel therapy had a superior effect on pain intensity as assessed by Visual Analogue Scale at the end of treatment[standardized mean difference(SMD):-0.64,95%CI:-1.22 to-0.06,I^(2)=80%,n=262;3 RCTs];on symptom resolution rate at 3-month follow-up(risk ratio:1.94,95%CI:1.47 to 2.56,n=1527,I^(2)=38%;13 RCTs);and on global menstrual symptoms score at the end of treatment(SMD:-0.67,95%CI:-0.90 to-0.45,I^(2)=63%,n=990;12 RCTs).Subgroup analyses showed either a better or an equivalent effect comparing navel therapy with Western *** major adverse

关键词： navel therapy Shenque primary dysmenorrhea quality of life systematic review meta-analysis

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基于卷烟消费大数据标签体系的六大画像系统

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中国烟草学报 2024年第1期30卷 108-114页

作者：邓超梁雪霞陈志许良本莫玉华朱博文谭茜廖国彬李安张欣广西中烟工业有限责任公司互联网研究中心南宁市530001 广西壮族自治区烟草公司玉林市公司营销中心玉林市537000

为解决卷烟消费者数据采集与分析难问题,提出了一种全新的基于时空网格技术的消费人群大数据采集分析方法。通过商圈网格划分和数据标签特征工程,实现企业消费者大数据资源的高效融合,建立卷烟消费大数据标签体系,提高了数据的使用价值... 详细信息

为解决卷烟消费者数据采集与分析难问题,提出了一种全新的基于时空网格技术的消费人群大数据采集分析方法。通过商圈网格划分和数据标签特征工程,实现企业消费者大数据资源的高效融合,建立卷烟消费大数据标签体系,提高了数据的使用价值和复用性。基于大数据、时空网格、可视化技术构建卷烟市场数字孪生体,设计实现了六大画像系统。以玉林市场为例,实现了5237个商圈画像、19544个终端画像、42个品牌画像、169个产品画像以及12种商圈类别画像、24种卷烟分类画像。基于系统对某卷烟品牌实施精准投放实验,该产品的货源利用率从35%提升至59%。

关键词：消费者数字画像大数据标签体系商圈可视化

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Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan liu Rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong Jiang Yan Jiang Jing-Wu Sun Qin-Tai yang xue-Zhong li Ya-Nan Sun li Shi Min Wang Xi-Cheng Song Fu-Quan Chen Xiao-Shu Zhang Hong-Quan Wei Shao-Qing Yu Dong-Dong zhu Luo Ba zhi-Wei Cao xu-Ping Xiao Xin Wei zhi-Hong lin Feng-Hong Chen Chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong Qu Chang-Qing Zhao Zhen-lin Wang Hua-Bin li Feng liu Xiao-Bo Cui Sheng-Nan Ye Zheng liu Yu xu Xiao Cai Wei Huang Ru-Xin Zhang Yu-lin Zhao Guo-Dong Yu Guang-Gang Shi Mei-Ping Lu yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-bing Xie Long-Gang Yu Ye-Hai liu Shao-Wei Gu Yu-Cheng yang Lei Cheng Jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

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不同桃品种幼果炮制瘪桃干的抗氧化活性与药用适宜性研究

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湖南农业科学 2024年第1期 51-59页

作者：陆泰良徐志美朱鹏翔李海炎梁瑞郑李怡杰梁欣万保雄广西桂北特色经济作物种质创新与利用重点实验室广西特色作物研究院广西桂林541004

研究不同桃品种幼果炮制瘪桃干的绿原酸类化合物含量和抗氧化活性,为综合开发利用桃幼果提供参考。以33份桃品种幼果为试材,采用60℃烘干(HAD60)、冷冻干燥(FD)和日光干燥(SD)炮制瘪桃干,通过测定瘪桃干样品DPPH自由基清除能力、总抗氧... 详细信息

研究不同桃品种幼果炮制瘪桃干的绿原酸类化合物含量和抗氧化活性,为综合开发利用桃幼果提供参考。以33份桃品种幼果为试材,采用60℃烘干(HAD60)、冷冻干燥(FD)和日光干燥(SD)炮制瘪桃干,通过测定瘪桃干样品DPPH自由基清除能力、总抗氧化能力和总酚、新绿原酸(5-CQA)、绿原酸(3-CQA)和隐绿原酸(4-CQA)含量评价不同品种桃幼果的抗氧化活性和药用适宜性。结果表明:同一品种3种炮制方式总酚含量、DPPH自由基清除能力和总抗氧化能力大小顺序均为FD>HAD60>SD;SD处理瘪桃干样品总酚含量(用没食子酸当量表示,GE)、DPPH自由基清除能力(用Trolox当量表示,TE)和总抗氧化能力变异范围分别为2.96~19.54 mg/g、2.11~9.13 mg/g和24.83~108.96 mmol/kg;3种炮制方式制备的样品中5-CQA、3-CQA和4-CQA含量顺序均为FD>HAD60>SD;SD处理瘪桃干样品的5-CQA、3-QCA和4-QCA变异范围分别为0.27~6.23、0.38~3.75和0.14~1.69 mg/g;5-CQA、3-CQA和4-CQA含量均与抗氧化指标呈极显著正相关(P<0.01),其中5-CQA与与抗氧化指标的相关性最强;33份供试品种幼果适合炮制瘪桃干的有25份,其中毛桃17份,油桃6份,观赏桃2份;桃幼果药用适宜性最好的品种分别为锦春、锦花和中桃11号,部分特异油桃(188、中油20号和春蜜)和观赏桃(红叶桃和北京S9)因幼果富含绿原酸类化合物而较适合炮制成瘪桃干。

关键词：桃幼果瘪桃干抗氧化能力药用适宜性绿原酸类化合物

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Tribological behaviour of two kinds of typical hydrogel contact lenses in different lubricants

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Biosurface and Biotribology 2019年第4期5卷 110-117页

作者： Dong Qin li-Ting zhu Teng Zhou zhi-Qiang liao Ming liang ling Qin Zhen-bing Cai Ophthalmology Department Chengdu Third People’s HospitalChengdu 610031People’s Republic of China Tribology Research Institute Key Laboratory of Advanced Technologies of MaterialsMinistry of EducationSouthwest Jiaotong UniversityChengdu 610031People’s Republic of China

Contact lenses have a special effect on the treatment of some eye *** tribological behaviour of soft contact lenses considerably influences their clinical *** wearing of contact lenses can lead to mechanical damage of the contact interface,which can lead to pathological changes in the *** this study,the sliding friction of two kinds of typical contact lens materials(hilaficon-B and lotrafilcon-B)in three lubricants(distilled water,care solution,and eye drop)and tribological parameters are studied,using PMMA as a *** have high water content but the dehydration rate is *** hydrogels have low initial water content but low dehydration *** friction test in distilled water gives the highest coefficient of friction *** care solution and eye drop significantly reduce the friction coefficient of the lens due to the formation of tribofilm.

关键词： friction behaviour coefficient

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2009—2023年中国16个省份急性呼吸道感染病例中人呼吸道合胞病毒的流行特征分析

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中华预防医学杂志 2024年第7期58卷 945-951页

作者：崔爱利夏百成朱贞谢智博孙利伟徐瑾许晶李忠赵林清龙晓茹于德山朱冰张凤穆敏谢会蔡亮朱云田晓灵王冰郜振国刘晓庆任斌知韩光跃胡孔新张燕传染病溯源预警与智能决策全国重点实验室、国家卫生健康委医学病毒和病毒病重点实验室、中国疾病预防控制中心病毒病预防控制所北京102206 长春市儿童医院精准医学研究中心长春130061 河南省疾病预防控制中心免疫预防与规划所郑州450016 陕西省疾病预防控制中心病毒病预防控制所西安710054 山东省疾病预防控制中心传染病预防控制所济南250014 首都儿科研究所病毒学研究室儿童病毒病病原学北京市重点实验室北京100020 重庆医科大学附属儿童医院感染科重庆400014 甘肃省疾病预防控制中心病原检测所兰州730000 广州市妇女儿童医疗中心病毒研究室广州510120 青岛市疾病预防控制中心(青岛市预防医学研究院)病毒性疾病检验所青岛266000 安徽理工大学公共卫生学院淮南232001 北京市疾病预防控制中心(北京市预防医学科学院、北京结核病控制研究与防治所)免疫预防所北京100013 湖南省疾病预防控制中心长沙410005 国家儿童医学中心首都医科大学附属北京儿童医院感染与病毒研究室北京100045 内蒙古自治区综合疾病预防控制中心免疫规划所呼和浩特010000 沈阳市疾病预防控制中心传染病防制所沈阳110000 新疆维吾尔自治区疾病预防控制中心传染病防治所乌鲁木齐830002 江西省疾病预防控制中心疾病控制检验所重大新发突发病毒性传染病江西省卫生健康重点实验室南昌330029 山西省疾病预防控制中心疾病检验科太原030012 河北省疾病预防控制中心病毒所石家庄050021 中国检验检疫科学研究院卫生检验与检疫研究所北京100123

目的了解2009—2023年我国16个省份急性呼吸道感染(ARI)病例中人呼吸道合胞病毒(HRSV)的流行特征。方法研究资料来源于2009—2023年我国16个省份ARI病例监测数据,共有28 278例ARI病例纳入研究。监测病例的临床标本进行了HRSV核酸筛查,... 详细信息

目的了解2009—2023年我国16个省份急性呼吸道感染(ARI)病例中人呼吸道合胞病毒(HRSV)的流行特征。方法研究资料来源于2009—2023年我国16个省份ARI病例监测数据,共有28 278例ARI病例纳入研究。监测病例的临床标本进行了HRSV核酸筛查,并分析不同年龄组、不同地区和不同月份病例的HRSV检出率差异。结果 2009年1月至2023年9月,共纳入28 278例ARI病例。病例年龄范围为<1月龄~112岁,年龄M(Q1,Q3)为3岁(1岁,9岁)。28 278例ARI病例中有3 062例HRSV核酸阳性,总检出率为10.83%。2009—2019年HRSV检出率为9.33%,病毒主要以冬春季流行为主。在新型冠状病毒感染(COVID-19)流行期间,HRSV检出率在6.32%~18.67%之间波动;2022年底至2023年初未出现HRSV传统的冬季流行高峰,在2023年4—5月出现了HRSV反季节流行。87.95%(2 693/3 062)HRSV阳性病例为 5岁以下的儿童,不同年龄组中HRSV检出率的差异具有统计学意义(P<0.001),呈现出随着年龄增加HRSV检出率降低的趋势(P<0.001),其中以<6月龄组患儿的HRSV检出率最高(25.69%)。和2009—2019年相比,2020—2023年期间不同年龄组的HRSV检出率从高到低的排序发生变化,HRSV阳性病例的年龄M(Q1,Q3)从1岁(6月龄,3岁)增加至2岁(11月龄,3岁)。结论通过连续15年的HRSV监测分析发现,5岁以下的儿童,尤其是<6月龄婴幼儿是HRSV感染的主要高发人群。COVID-19流行期间,我国HRSV流行水平和流行模式发生了变化。

关键词：人呼吸道合胞病毒急性呼吸道感染流行特征监测

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Synthesis and Electronic Structure of Triazasubporphyrin with Peripherally Low Symmetric Push-pull Substitutions

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Chinese Journal of Structural Chemistry 2020年第1期39卷 36-40,2页

作者： FAN Yu-xuan YUAN Tai-Yan LV Qing-yang li Min-zhi zhu Wei-Hua liang xu School of Chemistry and Chemical Engineering Jiangsu UniversityZhenjiang 212013China

Peripherally low symmetric substitution with electron-donating(EDG)and electron-withdrawing(EWG)substituents caused the rational modulation of geometric structure and even the electronic structure of triazasubporphyrin,the smallest 14πconjugated *** structural characterization and spectroscopic investigation were discussed to provide an in-depth understanding of the relationship between peripheral push-pull substituents and SubPz core.

关键词： triazasubporphyrin push-pull effect electronic structure seterochemistry

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Synthesis and Characterization of a Squarylium Cyanine Dye with Two [60]Fullerene Units

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Chinese Chemical Letters 2001年第8期12卷 683-686页

作者： Chi Min DU Ju Hua xu Yu liang li zhi Qiang SHI Shu WANG Dao Ben zhu Center of Molecular Sciences Institute of ChemistryChinese Academy of SciencesBeijing 100080

A new [60]fullerene dimer 2 in which two C-60 units are covalently attached to a squarylium cyanine dye has been synthesized and characterized.

关键词： Fullerene dimer squarylium cyanine dye

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Modifying optical properties of ZnO nanowires via strain-gradient

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Frontiers of physics 2013年第5期8卷 509-515页

作者： xue-Wen Fu Qiang Fu liang-zhi Kou Xin-li zhu Rui zhu Jun xu zhi-Min liao Qing Zhao Wan-lin Guo Da-Peng Yu State Key Laboratory for Mesoscopic Physics and Electron Microscopy Laboratory Department of Physics Peking University Beijing 100871 China State Key Laboratory for Mechanics and Control of Mechanical Structures and MOE Key Laboratory of IntelligentNano Materials and Devices Institute of Nano Science Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

We conduct systematical cathodolumiuescence study on red-shift of near-band-edge emission energy in elastic bent ZnO nanowires with diameters within the exciton diffusion length （- 200 nm） in liquid nitrogen temperature （81 K）. By charactering the emission spectra of the nanowires with different; local curvatures, we find a linear relationship between strain-gradient and the red-shift of near-band-edge emission photon energy, an elastic strain-gradient effect in semiconductor similar to the famous flexoelectric effect in liquid crystals. Our results provide a new route to understand the inhomogeneous strain effect on the energy bands and optical properties of semiconductors and should be useful for designing advanced nano-optoelectronic devices.

关键词： strain-gradient ZnO nanowire cathodoluminescene exciton energy energy bands

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Rapid diagnosis of disseminated Mycobacterium mucogenicum infection in formalin-fixed, paraffin-embedded specimen using nextgeneration sequencing: A case report

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World Journal of Clinical Cases 2021年第20期9卷 5621-5630页

作者： Jing liu Zi-Ying Lei Yi-Hua Pang Ying-Xiong Huang Le-Jia xu Jian-Yun zhu Jia-Xing Zheng Xiao-Hua yang bing-liang lin zhi-liang Gao Chao zhuo Department of Infectious Diseases The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510630Guangdong ProvinceChina Department of Emergency The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510000Guangdong ProvinceChina Department of Pharmacy The Third Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510630Guangdong ProvinceChina State Key Laboratory of Respiratory Disease The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Mycobacterium mucogenicum(***)belongs to the group of rapidly growing Nontuberculous *** microorganism is associated with a wide spectrum of infectious *** to a low detection rate or the time required for conventional culture methodology,a rapid and broad-spectrum method is necessary to identify rare *** SUMMARY A 12-year-old immunocompetent girl presented with painful masses for five *** first mass was found in the right upper quadrant of the abdomen,and was about 1 cm×1.5 cm in size,tough but pliable in texture,with an irregular margin and *** abscess gradually formed and ulcerated with suppuration of the *** new masses appeared on the back one by *** computed tomography showed patchy and streaky cloudy opacities in both *** aspiration of the abscess was performed,but the smear and conventional culture were negative,and the pathological examination showed no *** then performed next-generation sequencing using a formalinfixed,paraffin-embedded specimen to identify the pathogen.A significantly high abundance of *** was *** patient’s abscesses gradually decreased in size,while inflammation in both lungs improved following 12-wk of *** recurrence was observed four months after the end of the one-year treatment *** Next-generation sequencing is a promising tool for the rapid and accurate diagnosis of rare pathogens,even when using a formalin-fixed,paraffin-embedded specimen.

关键词： Mycobacterium mucogenicum Next-generation sequencing Disseminated infection Formalin-fixed,paraffin-embedded specimen Rapid diagnosis Case report

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