Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals
Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China: A national multicenter survey of 35,566 individuals作者机构：Graduate School of Beijing University of Chinese MedicineBeijingChina Department of Otorhinolaryngology Head and Neck SurgeryChina-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck SurgeryThe First People's Hospital of YinchuanYinchuanChina Department of OtorhinolaryngologyThe First People's Hospital of Yunnan ProvinceKunmingChina Department of OtorhinolaryngologyThe First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck SurgeryXiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck SurgeryThe Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck SurgeryThe Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck SurgeryQilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck SurgeryThe Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of OtolaryngologyThe Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck SurgeryPeking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck SurgeryYantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck SurgeryXijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and PreventionLanzhouChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck SurgeryTongji HospitalTongji Medical UniversityShanghaiChina Department of Otorhinolaryngology Head and Neck SurgeryChina-Japan Union Hospital of Jilin UniversityChangchunChina Department of Otorhinolaryngology Head and Neck SurgeryXizang Autonomous Region People's HospitalLasaChina Department of Otorhinolaryngology Head and Neck SurgeryShengjing Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck SurgeryHunan Provincial People's HospitalChangshaChina Department of Otorhinolaryngology Head and Neck SurgeryHainan General HospitalHaikouChina Department of Otorhinolaryngology Head and Neck SurgeryThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhouChina Department of OtorhinolaryngologyThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck SurgeryThe Second Hospital of Hebei Medical UniversityShijiazhuangChina Department of Otorhinolaryngology Head and Neck SurgeryHenan Provincial People's HospitalZhengzhouChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Nanchang UniversityNanchangChina Department of Otorhinolaryngology Head and Neck SurgeryGuangxi Zhuang Autonomous Region People's HospitalNanningChina Department of Otorhinolaryngology Head and Neck SurgeryShanxi Medical University Affiliated Second HospitalTaiyuanChina Department of Otorhinolaryngology Head and Neck SurgeryXuanWu HospitalCapital Medical UniversityBeijingChina Department of Otorhinolaryngology Head and Neck SurgeryEyeEarNose and Throat HospitalShanghai Medical CollegeFudan UniversityShanghaiChina Department of Otorhinolaryngology Head and Neck SurgeryWest China HospitalSichuan UniversityChengduChina Department of Otorhinolaryngology Head and Neck SurgeryAffiliated Hospital of Inner Mongolia Medical UniversityHohhotChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Fujian Medical UniversityFuzhouChina Department of Otorhinolaryngology Head and Neck SurgeryTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Otorhinolaryngology Head and Neck SurgeryRenmin Hospital of Wuhan UniversityWuhanChina Department of Otorhinolaryngology Head and Neck SurgeryQinghai Provincial People's HospitalXiningChina Department of Otorhinolaryngology Head and Neck SurgeryTianjin Huanhu HospitalTianjinChina Department of Otorhinolaryngology Head and Neck SurgeryHuadong Hospital Affiliated to Fudan UniversityShanghaiChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Zhengzhou UniversityZhengzhouChina Department of Otorhinolaryngology Head and Neck SurgeryAffiliated Hospital of Guizhou Medical UniversityGuiyangChina Department of Otorhinolaryngology Head and Neck SurgeryShandong Provincial HospitalAffiliated to Shandong First Medical UniversityJinanChina Department of Otorhinolaryngology&Clinical Allergy CenterThe First Affiliated HospitalNanjing Medical UniversityNanjingChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Chongqing Medical UniversityChongqingChina Department of Otorhinolaryngology Head and Neck SurgeryThe First Affiliated Hospital of Anhui Medical UniversityHefeiChina
出 版 物：《World Journal of Otorhinolaryngology-Head and Neck Surgery》 (世界耳鼻咽喉头颈外科杂志（英文）)
年 卷 期：2024年第10卷第2期
页 面：113-120页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学]
基 金：National High Level Hospital Clinical Research Funding,Grant/Award Number:2022-NHLHCRF-YGJE-02 Natural Science Foundation of Beijing Municipality,Grant/Award Number:7212090
主 题：epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders
摘 要：Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.
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