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Carotid artery endarterectomy in patients with symptomatic non-stenotic carotid artery disease

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Stroke & Vascular Neurology 2022年第3期7卷 251-257页

作者： Valentina Nardi John C benson Anthony S Larson Waleed Brinjikji Luca Saba Fredric B Meyer Giuseppe Lanzino Amir Lerman Luis E Savastano Department of Cardiovascular Diseases Mayo ClinicRochesterMinnesotaUSA Radiology Mayo ClinicRochesterMinnesotaUSA Radiology Azienda Ospedaliero UniversitariaCagliariItaly Neurosurgery Mayo ClinicRochesterMinnesotaUSA

Object We sought to determine the safety and efficacy in secondary stroke prevention of carotid endarterectomy(CEA)in patients with symptomatic non-stenotic carotid artery disease(SyNC).Methods This was a single-centre retrospective case *** patients who underwent CEA for unilateral anterior circulation cerebrovascular events with ipsilateral<50%carotid stenosis from 2002 to 2020 were *** hallmarks including the degree of luminal stenosis and the presence of various vulnerable plaque characteristics(eg,intraplaque haemorrhage(IPH)on MR angiography,ulceration or low-density plaque on CT angiography)were *** presence of vulnerable plaque characteristics was compared between arteries ipsilateral to the ischaemic event and contralateral *** prevalence of perioperative/intraoperative complications,as well as recurrent ischaemic events at follow-up was *** Thirty-two patients were included in the analysis,of which 25.0%were *** arteries ipsilateral to an ischaemic event had a significantly higher prevalence of IPH when compared with contralateral arteries(80.0%vs 0.0%;p<0.001).There were no intraoperative *** patient(3.1%)developed symptoms of transient ipsilateral ischaemia 1 day following CEA which resolved without *** a median follow-up of 18.0 months(IQR 5.0-36.0),only one patient(3.1%)experienced a transient neurologic deficit with complete resolution(annualised rate of recurrent stroke after CEA of 1.5%for a total follow-up of 788 patient-months following CEA).All other patients(31/32,96.9%)were free of recurrent ischaemic *** CEA appears to be safe and well-tolerated in patients with *** studies with larger cohorts and longer follow-up intervals are needed in order to determine the role of CEA in this patient population.

关键词： patients carotid prevention

Effects of genistein and equol on human and rat testicular 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase 3 activities

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Asian Journal of Andrology 2010年第4期12卷 519-526页

作者： Guo-Xin Hu Bing-Hai Zhao Yan-Hui Chu Hong-Yu Zhou benson T. Akingbemi Zhi-Qiang Zheng Ren-Shan Ge Population Council New York NY 10065 USA School of Pharmacy Wenzhou Medical College Wenzhou 325000 China Heilongjiang Key Laboratory of Anti-fibrosis Biotherapy Mudanjiang Medical University Mudanjiang 157001 China Departments of Anatomy Physiology and Pharmacology Auburn University Auburn AL 36849 USA The Second Affiliated Hospital Wenzhou Medical College Wenzhou 325000 China

The objective of the present study was to investigate the effects of genistein and equol on 3β-hydroxysteroid de- hydrogenase （3β-HSD） and 17β-hydroxysteroid dehydrogenase 3 （17β-HSD3） in human and rat testis microsomes. These enzymes （3β-HSD and 17β-HSD3）, along with two others （cytochrome P450 side-chain cleavage enzyme and cytochrome P450 17α-hydroxylase/17-20 lyase）, catalyze the reactions that convert the steroid cholesterol into the sex hormone testosterone. Genistein inhibited 3β-HSD activity （0.2 μmol L^-1 pregnenolone） with half-maximal inhibition or a half-maximal inhibitory concentration （IC50） of 87 ± 15 （human） and 636 ± 155 nmol L^-1 （rat）. Genistein＇s mode of action on 3β-HSD activity was competitive for the substrate pregnenolonrge and noncompetitive for the cofactor NAD＋. There was no difference in genistein＇s potency of 3β-HSD inhibition between intact rat Leydig cells and testis microsomes. In contrast to its potent inhibition of 3β-HSD, genistein had lesser effects on human and rat 17β-HSD3 （0.1 μmol L^-1 androstenedione）, with an IC50 〉 100μmol L^-1. On the other hand, equol only inhibited human 3β-HSD by 42%, and had no effect on 3β-HSD and 17β-HSD3 in rat tissues. These observations imply that the ability of soy isoflavones to regulate androgen biosynthesis in Leydig cells is due in part to action on Leydig cell 3β- HSD activity. Given the increasing intake of soy-based food products and their potential effect on blood androgen levels, these findings are greatly relevant to public health.

关键词： 3β-hydroxysteroid dehydrogenase 17β-hydroxysteroid dehydrogenase 3 enzyme inhibition equol genistein

Anglo-Dutch Relations and the Amboyna Massacre

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History Research 2012年第3期2卷 173-177页

作者： Joel D. benson Northwest Missouri State University Maryville USA

The economic relationship between the Dutch and the English was long established by the beginning of the Stuart era. With the accession of James I this situation began to change. The Treaty of London ended almost two decades of English military cooperation with the Dutch, and English and Dutch factors in the East Indies began competing not only with the Iberians but with each other. In 1619, representatives of both countries reached an agreement in London for joint access to the spice markets of the East Indies. Despite these efforts of business and government leaders, the Amboyna massacre marked the end of any real chance of Anglo-Dutch cooperation in the East Indies.

关键词： Anglo-Dutch relationship the Amboyna massacre East Indies spice trade

Hospital Uses Pill with Camera Inside

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当代外语研究 2004年第8期 5-7页

作者： AVA Thomas benson 施建中南大学

可曾想过药丸里能放置照相机?美国阿肯色州儿童医院的胃肠科医生们正在使用这种只有一般女性指尖大小、内置摄像机的药丸(M2A Capsule)来代替传统的胃镜,检查儿童的肠胃疾病。这种高新技术能否完全取代传统技术?专家们各有说法。

关键词： than

Rethinking Microbiology Education for the 21st Century:Using ASM Educational Resources to Reform Microbiology Education

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Rethinking Microbiology Education for the 21st Century:Using...

Message from the Guest Editors

2008年中国微生物学会学术年会

作者： Spencer benson University of Maryland College Park MD ASM International Education Committee

Effectively training students to be 21century microbiologists and teacher requires new teaching techniques and new educational materials and new way for training *** interactive presentation will highlight the numerous educational resources from the American Society for Microbiology(ASM) that are available to teachers and students to help them become 21century microbiologist and teachers.

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Chinese Journal of Applied Linguistics 2013年第1期36卷 3-5页

作者： HUANG Jing Phil benson Department of Education Studies Hong Kong Baptist University Department of Linguistics and Modern Language Studies The Hong Kong Institute of Education Studies

The articles in this special issue are based on a selection of more than 40 papers on autonomy in second and foreign language education presented at the 16th AILA World Congress in Beijing in August 2011. The opening review article,by the guest editors,explores autonomy and related constructs at a theoretical *** is followed by seven data-based research papers from China,Britain,Finland,Mexico,and Japan,which represent the international scope of research on autonomy at the present *** work as a whole examines how autonomy is conceptualized in different institutional,socio-cultural and political environments,

关键词：留言编辑世界大会自主权

使用嵌入式处理器的水声调制解调器控制系统设计方法与研究

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北京大学学报（自然科学版） 2011年第2期47卷 245-250页

作者：李莹 Bridget benson 于敦山 Ryan Kastner 张兴北京大学信息科学技术学院微电子学系北京100871 Department of Computer Science and Engineering University of California San Diego San Diego CA 92093

提出了一种使用带有嵌入式处理器的FPGA实现水声调制解调器控制系统的方法,根据声波通信的数据特点选择适合的通信总线搭建系统结构,设计出合理的软硬件协同工作流程和中断控制信号。通过在Xilinx VirtexIVFPGA的嵌入式MicroBlaze软处... 详细信息

提出了一种使用带有嵌入式处理器的FPGA实现水声调制解调器控制系统的方法,根据声波通信的数据特点选择适合的通信总线搭建系统结构,设计出合理的软硬件协同工作流程和中断控制信号。通过在Xilinx VirtexIVFPGA的嵌入式MicroBlaze软处理器上实现并通过软硬件协同验证,表明所设计的控制系统能够准确控制整个数字信号处理过程,实时监控电路工作情况,性能稳定可靠。

关键词：嵌入式系统软处理器水声调制解调器控制系统软硬件协同

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亨利·布雷德肖

中国翻译 2008年第6期29卷 69-70页

作者： Arthur Christopher benson 刘士聪南开大学·外国语学院

当谈起布雷德肖的“工作”时，很难让不熟悉情况的人明白那是多么广泛，多么重要，或多么完美。关于书籍，他比在世的任何人知道的都多——他只要看上一眼，就能说出一本书出版的时期、国家，甚至常常具体到城市。这一学科所涵盖的庞大... 详细信息

当谈起布雷德肖的“工作”时，很难让不熟悉情况的人明白那是多么广泛，多么重要，或多么完美。关于书籍，他比在世的任何人知道的都多——他只要看上一眼，就能说出一本书出版的时期、国家，甚至常常具体到城市。这一学科所涵盖的庞大领域，若没有同样广博的专业知识是不能说清楚的。他是最杰出的研究乔叟的学者之一，一个通晓多种语言、能力很强的语言学家（虽然只是为了阅读，而不是为了讲话），比如，

关键词：雷德亨利语言学家专业知识国家

Time-resolved terahertz spectroscopy of charge carrier dynamics in the chalcogenide glass As_(30)Se_(30)Te_(40)[Invited]

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Photonics Research 2016年第3期4卷 22-28页

作者： Tianwu Wang Elena A.Romanova Nabil Abdel-Moneim David Furniss Anna Loth Zhuoqi Tang Angela Seddon Trevor benson Andrei Lavrinenko Peter Uhd Jepsen Department of Photonics Engineering (DTU Fotonik) Technical University of Denmark Saratov State University Department of Physics Faculty of Engineering University of Nottingham

Broadband(1.6–18 THz) terahertz time-domain spectroscopy(THz-TDS) and time-resolved terahertz spectroscopy(TRTS) were performed on a 54 μm thick chalcogenide glass(As_(30)Se_(30)Te_(40)) sample with a two-color laser-induced air plasma THz system in transmission and reflection modes, respectively. Two absorption bands at 2–3 and 5–8 THz were observed. TRTS reveals an ultrafast relaxation process of the photoinduced carrier response, well described by a rate equation model with a finite concentration of mid-bandgap trap states for self-trapped *** photoinduced conductivity can be well described by the Drude–Smith conductivity model with a carrier scattering time of 12–17 fs, and we observe significant carrier localization effects. A fast refractive index change was observed 100 fs before the conductivity reached its maximum, with 2 orders of magnitude larger amplitude than expected for the optically induced THz Kerr effect, indicating that free carriers are responsible for the transient index change.

关键词： Te Invited Se Time-resolved terahertz spectroscopy of charge carrier dynamics in the chalcogenide glass As