检索结果-南通市图书馆

Nrf2 as a potential target for the treatment of epilepsy

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第9期19卷 1865-1866页

作者： Prince kumar Singh Tawfeeq Shekh-Ahmad Institute for Drug Research School of PharmacyFaculty of MedicineThe Hebrew University of JerusalemJerusalemIsrael

Epilepsy is a prevalent chronic brain disorder that is characterized by a persistent predisposition to recurrently generate epileptic seizures and is often associated with cognitive and psychological *** affects approximately 65 million individuals,including both males and females of all ages worldwide,and poses a significant burden on patients,their families,and the health system(Vezzani et al.,2019).

关键词： epilepsy Nrf2

Investigation of proton structure function F_(2)^(p)at HERA in light of an analytical solution to the Balitsky–Kovchegov equation

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2024年第3期76卷 120-126页

作者： Ranjan Saikia Pragyan Phukan Jayanta kumar Sarma HEP laboratory Department of PhysicsTezpur UniversityTezpurAssam-784028India Department of Physics Moran CollegeMoranhatAssam-785670India

In this paper,the proton structure function F_(2)^(p)(x,Q^(2))at small-x is investigated using an analytical solution to the Balitsky–Kovchegov(BK)*** the context of the color dipole description of deep inelastic scattering(DIS),the structure function F_(2)^(p)(x,Q^(2))is computed by applying the analytical expression for the scattering amplitude N(k,Y)derived from the BK *** transverse momentum k and total rapidity Y,the scattering amplitude N(k,Y)represents the propagation of the quark-antiquark dipole in the color dipole description of *** the BK solution we extracted the integrated gluon density xg(x,Q^(2))and then compared our theoretical estimation with the LHAPDF global data fits,NNPDF3.1sx and ***,we have investigated the behavior of F_(2)^(p)(x,Q^(2))in the kinematic region of 10^(-5)≤x≤10^(-2)and 2.5 GeV^(2)≤Q^(2)≤60 GeV^(2).Our predicted results for F_(2)^(p)(x,Q^(2))within the specified kinematic region are in good agreement with the recent high-precision data for F_(2)^(p)(x,Q^(2))from HERA(H1 Collaboration)and the LHAPDF global parametrization group NNPDF3.1sx.

关键词： quantum chromodynamics(QCD) perturbative QCD(pQCD) proton structure function small-x Balitsky-Kovchegov equation

Review of Electrochemical Sensors and Biosensors Based on First-Row Transition Metals,Their Oxides,and Noble Metals Nanoparticles

在线全文

学校读者我要写书评

暂无评论

Journal of Analysis and Testing 2024年第2期8卷 143-159页

作者： Kulveer Singh Kuldeep kumar Maurya Manisha Malviya Department of Chemistry Indian Institute of Technology(Banaras Hindu University)Varanasi221005India

The use of electrochemical sensors for sensitive disease diagnosis and detecting various species with pharmacological,therapeutic,industrial,food-related,and environmental origins is now widely accepted.A catalytic or binding event resulting from the sensor’s electroactive component recognizing its analyte creates an electrical signal proportionate to the analyte concentration,which is then monitored by a *** development of morphologically distinct metal and metal oxide nanoparticles formed from first-row transition elements(Mn,Cr,Fe,Co,Ti,Ni,Cu,Zn)and noble metals(Pt,Au,Ag,Pd)is described in this *** effect of these metal nanoparticles has been studied using Tetracyanoquinodimethane(TCNQ),Ferrocene,and other organic compounds as electroactive species using carbon paste-modified *** sensors,mostly based on ferrocene,are exceedingly sensitive,selective,affordable,and for detecting numerous biomolecules like glucose,dopamine,NADH,ascorbic acid,and a few dyes and are simple to *** recent decades,charge transfer organic species-based chemosensors have become a prominent study *** paper outlines current developments in electrochemical biosensors based on transition metal nanoparticles,covering glucose,ascorbic acid,uric acid,and other inorganic and organic *** importance of transition metal and transition metal oxide nanoparticles as potential electrode modifiers for developing sensors is highlighted.A discussion of the present problem and possible solutions,and plausible future directions marks the review’s conclusion.

关键词： Electrochemical sensing Amperometry Cyclic voltammetry Square wave voltammetry Linear sweep voltammetry

Dilation,discrimination and Uhlmann's theorem of link products of quantum channels

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第3期33卷 201-206页

作者：雷强操刘桁 Asutosh kumar 武俊德 School of Mathematical Sciences Harbin Institute of TechnologyHarbin 150001China Department of Physics Gaya CollegeMagadh UniversityRampurGaya 823001India School of Mathematical Sciences Zhejiang UniversityHangzhou 310027China

We establish the Stinespring dilation theorem of the link product of quantum channels in two different ways,discuss the discrimination of quantum channels,and show that the distinguishability can be improved by self-linking each quantum channel n times as n *** also find that the maximum value of Uhlmann's theorem can be achieved for diagonal channels.

关键词： quantum channels link products Stinespring dilation theorem Uhlmann's theorem

Drug resistance mechanisms in cancers:Execution of prosurvival strategies

在线全文

学校读者我要写书评

暂无评论

Journal of Biomedical Research 2024年第2期38卷 95-121页

作者： Pavan kumar Dhanyamraju Fels Cancer Institute of Personalized Medicine Lewis-Katz School of MedicineTemple UniversityPhiladelphiaPA 19140USA

One of the quintessential challenges in cancer treatment is drug *** mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be *** phenomenon of cancer drug resistance is now widespread,with approximately 90% of cancer-related deaths associated with drug *** significant advances in the drug discovery process,the emergence of innate and acquired mechanisms of drug resistance has impeded the progress in cancer ***,understanding the mechanisms of drug resistance and the various pathways involved is integral to treatment *** the present review,I discuss the different mechanisms of drug resistance in cancer cells,including DNA damage repair,epithelial to mesenchymal transition,inhibition of cell death,alteration of drug targets,inactivation of drugs,deregulation of cellular energetics,immune evasion,tumor-promoting inflammation,genome instability,and other contributing epigenetic ***,I highlight available treatment options and conclude with future directions.

关键词： cancer drug resistance mechanisms microRNAs treatment strategies

Protected simultaneous quantum remote state preparation scheme by weak and reversal measurements in noisy environments

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第2期33卷 169-177页

作者： Mandal Manoj kumar Choudhury Binayak S. Samanta Soumen Department of Mathematics Indian Institute of Engineering Science and TechnologyShibpur B.GardenHowrah 711103West BengalIndia

We discuss a quantum remote state preparation protocol by which two parties, Alice and Candy, prepare a single-qubit and a two-qubit state, respectively, at the site of the receiver Bob. The single-qubit state is known to Alice while the two-qubit state which is a non-maximally entangled Bell state is known to Candy. The three parties are connected through a single entangled state which acts as a quantum channel. We first describe the protocol in the ideal case when the entangled channel under use is in a pure state. After that, we consider the effect of amplitude damping(AD) noise on the quantum channel and describe the protocol executed through the noisy channel. The decrement of the fidelity is shown to occur with the increment in the noise parameter. This is shown by numerical computation in specific examples of the states to be created. Finally, we show that it is possible to maintain the label of fidelity to some extent and hence to decrease the effect of noise by the application of weak and reversal measurements. We also present a scheme for the generation of the five-qubit entangled resource which we require as a quantum channel. The generation scheme is run on the IBMQ platform.

关键词： multi-qubit entangled channel quantum remote state preparation noisy environments weak and reversal measurements

Helicobacter pylori isolated from gastric juice have higher pathogenic potential than biopsy isolates

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 34-37页

作者： Budhadev Baral Dharmendra Kashyap Nidhi Varshney Tarun Prakash Verma Ajay kumar Jain Debi Chatterji Vinod kumar Amit Mishra Awanish kumar Hem Chandra Jha Infection Bioengineering Group Department of Biosciences and Biomedical EngineeringIndian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Choithram Hospital and Research Center IndoreMadhya Pradesh452014India Department of Metallurgy Engineering and Materials Science Indian Institute of Technology IndoreSimrolIndoreMadhya Pradesh 453552India Department of Bioscience&Bioengineering Indian Institute of Technology JodhpurNH 65 Nagaur RoadJodhpur DistrictKarwarRajasthan 342037India Department of Biotechnology National Institute of Technology RaipurGE RoadRaipurChhattisgarh 492010India

Persistent gastritis induced by Helicobacter pylori(***)is the strongest known risk factor for gastric cancer(GC).*** is prevalent in about 50%world's population,while it causes cancer in less than 2%of exposed individuals.1 Our studies found that *** infection can induce oncogenic properties in AGS cells by deregulating multiple factors associated with the cell cycle,apoptosis,and other important events associated with cancer progression.

关键词： H.pylori pylori Helicobacter

Effect of random movement and cooperative hunting in the prey-predator system:A dynamical approach

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Biomathematics 2024年第3期17卷 211-240页

作者： Shivam Teekam Singh Mukesh kumar Department of Mathematics Graphic Era Deemed to be University 566/6 Bell RoadSociety AreaClenent Town DehradunUttarakhand 248002India Department of Computer Science and Engineering Graphic Era Deemed to be University 566/6 Bell RoadSociety AreaClement Town DehradunUttarakhand 248002India

Self-diffusion prerequisite is obtained as the spreading approach of biological *** hunting is a common behavior in predator populations that promotes predation and the coexistence of the prey-predator *** the other side,the Allee effect among prey may cause the system to become *** this paper,a difusive prey predator system with cooperative hunting and the weak Allee effect in prey populations is *** linear stability and Hopf-bifurcation analysis had been used to examine the system's *** the spatial stability of the system,the conditions for Turing instability have been *** multiple-scale analysis has been used to derive the amplitude equations of the *** stability analysis of these amplitude equations leads to the formation of Turing ***,numerical simulations are used to analyze spatial patterns forming in 1-D and *** studies indicate that the model can generate a complex pattern structure and that self-diffusion has a drastic impacton species distribution.

关键词： Prey predator system hunting cooperation Allee effect Hopf-bifurcation diffusive instability amplitudeequation

Effective data transmission through energy-efficient clustering and Fuzzy-Based IDS routing approach in WSNs

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

虚拟现实与智能硬件（中英文） 2024年第1期6卷 1-16页

作者： Saziya TABBASSUM Rajesh kumar PATHAK Research Scholar Department of Computer ScienceOPJS University ChuruSadulpurRajasthan 331303India Vice Chancellor OPJS University ChuruSadulpurRajasthan 331303India

Wireless sensor networks(WSN)gather information and sense information samples in a certain region and communicate these readings to a base station(BS).Energy efficiency is considered a major design issue in the WSNs,and can be addressed using clustering and routing *** is sent from the source to the BS via routing ***,these routing protocols must ensure that packets are delivered securely,guaranteeing that neither adversaries nor unauthentic individuals have access to the sent *** data transfer is intended to protect the data from illegal access,damage,or ***,in the proposed model,secure data transmission is developed in an energy-effective manner.A low-energy adaptive clustering hierarchy(LEACH)is developed to efficiently transfer the *** the intrusion detection systems(IDS),Fuzzy logic and artificial neural networks(ANNs)are ***,the nodes were randomly placed in the network and initialized to gather *** ensure fair energy dissipation between the nodes,LEACH randomly chooses cluster heads(CHs)and allocates this role to the various nodes based on a round-robin management *** intrusion-detection procedure was then utilized to determine whether intruders were present in the *** the WSN,a Fuzzy interference rule was utilized to distinguish the malicious nodes from legal ***,an ANN was employed to distinguish the harmful nodes from suspicious *** effectiveness of the proposed approach was validated using metrics that attained 97%accuracy,97%specificity,and 97%sensitivity of 95%.Thus,it was proved that the LEACH and Fuzzy-based IDS approaches are the best choices for securing data transmission in an energy-efficient manner.

关键词： Low energy adaptive clustering hierarchy(LEACH) Intrusion detection system(IDS) Wireless sensor network(WSN) Fuzzy logic and artificial neural network(ANN)