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Silicene nanorib.ons on transition metal dichalcogenide sub.trates： Effects on electronic structure and b.llistic transport

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Nano Research 2016年第11期9卷 3394-3406页

作者： b.s van den broek Michel Houssa Augustin Lu Geoffrey Pourtois Valery Afanas'ev Andre Stesmans Semiconductor Physics Lab.ratory Department of Physics and Astronomy University of Leuven Celestijnenlaan 200 D B-3001 Leuven Belgium imec 75 Kapeldreef B-3001 Leuven Belgium Department of Chemistry Plasmant Research Group University of Antwerp B-2610 Wilrijk-Antwerp Belgium

The idea of stacking multiple monolayers of different two-dimensional materials has b.come a glob.l pursuit. In this work a silicene armchair nanorib.on of width W and van der Waals-b.nded to different transition-metal dichalcogenide （TMD） b.layer sub.trates MoX2 and WX2, where X = S, Se, Te is considered. The orb.tal resolved electronic structure and b.llistic transport properties of these systems are simulated b. employing van der Waals-corrected density functional theory and nonequilib.ium Green＇s functions. We find that the lattice mismatch with the underlying sub.trate determines the electronic structure, correlated with the silicene b.ckling distortion and ultimately with the contact resistance of the two-terminal system. The smallest lattice mismatch, ob.ained with the MoTe2 sub.trate, results in the silicene rib.on properties coming close to those of a freestanding one. With the TMD b.layer acting as a dielectric layer, the electronic structure is tunab.e from a direct to an indirect semiconducting layer, and sub.equently to a metallic electronic dispersion layer, with a moderate applied perpendicular electric field.

关键词： silicene transition metal dichalcogenides van der Waals heterostructure electronic structure b.llistic transport

Topological to trivial insulating phase transition in stanene

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Nano Research 2016年第3期9卷 774-778页

作者： Michel Houssa b.s van den broek Konstantina Iordanidou Anh Khoa Augustin Lu Geoffrey Pourtois Jean-Pierre Locquet Valery Afanas'ev Andre Stesmans Department of Physics and Astronomy University of Leuven Celestijnenlaan 200D B-3001 Leuven Belgium imec 75 Kapeldreef B-3001 Leuven Belgium

Electronic properties of stanene, the Sn counterpart of graphene are theoretically studied using first-principles simulations. The topological to trivial insulating phase transition induced b. an out-of-plane electric field or b. quantum confinement effects is predicted. The results highlight the potential to use stanene nanorib.ons in gate-voltage controlled dissipationless spin-b.sed devices and are used to set the minimal nanorib.on width for such devices, which is typically approximately 5 nm.

关键词： two-dimensional (2D)materials topological insulators density functional theory(DFT) simulations electronic structure

Impact of b.ack cherry on pedunculate oak vitality in mixed forests:b.lancing b.nefits and concerns

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Forest Ecosystems 2023年第6期10卷 690-699页

作者： Ellen Desie b.rt Muys Jan den Ouden b.rt Nyssen Rita Sousa-Silva Leon van den b.rg Arnold van den b.rg Gert-Jan van Duinen Koenraad van Meerb.ek Maaike Weijters Karen vancampenhout Division Forest Nature and LandscapeKU Leuven Campus GeelKleinhoefstraat 4B-2240 GeelBelgium Division Forest Nature and LandscapeKU LeuvenCelestijnenlaan 200EBox 2411B-3001 LeuvenBelgium KU Leuven Plant Institute B-3001 LeuvenBelgium Forest Ecology and Management Group Wageningen UniversityP.O.Box 47Wageningenthe Netherlands b.sgroep Zuid-Nederland Huisvenseweg 145591 VD Heezethe Netherlands Young Academy for Sustainab.lity Research University of Freiburg79104 Freiburg im BreisgauGermany Aquatic Ecology&Environmental b.ology Radboud University NijmegenHeyendaalseweg 1356525 AJ Nijmegenthe Netherlands b.osphere/Zoological Museum Netherlands Onderlangs 176731 BK Otterlothe Netherlands Stichting b.rgerveen Toernooiveld 16525 ED Nijmegenthe Netherlands b.WARE Research Centre/Radb.ud University Nijmegen Toernooiveld 16525 ED Nijmegenthe Netherlands

The vitality of European forests continues to decline due to new pests and diseases,climate-change related disturb.nces and high loads of atmospheric nitrogen *** soil health is a major factor underpinning the low vitality of West-European *** tree species with soil ameliorative traits is proposed as an avenue to counteract soil acidification and improve overall forest *** we evaluate the impact of b.ack cherry(Prunus serotina Ehrh.),a known rich litter species,on the vitality of neighb.ring pedunculate oak(Quercus rob.r L.)in ten mixed forests on sand in Germany,b.lgium and the *** found that b.ack cherry admixture increases foliar N and P to a surplus whereas it causes deficiencies in foliar Mg,thereb. resulting in an overall negative effect on oak foliar nutrient ***,defoliation of oak leaves b. herb.vory decreases with the proximity of b.ack *** structural equation modelling(SEM),we tested the hypothesized‘improved soil health’*** analyses showed that b.ack cherry admixture leads to lower accumulation in the humus layer,resulting in higher soil b.se saturation which has a positive effect on foliar Ca yet a negative effect on total ***,the SEM illustrated that herb.vory of oak leaves decreases when b.ack cherry is admixed,b.th via dilution and improved soil *** effects of b.ack cherry on oak vitality via“improved soil health”in our SEM are however small in comparison to direct ***,our study showed that the comb.ned positive and negative impacts of b.ack cherry on oak vitality are limited,which tempers the potential b.nefits of using the rich litter species to counteract oak decline via improved soil health–yet,the concern of b.ack cherry as an invasive alien species negatively affecting the vitality of mature pedunculate oak trees may also b. exaggerated.

关键词： Rich litter species b.ack cherry Nutrient cycling Insect herb.vory Dilution effect Humus type Pedunculate oak Plant-soil interaction

Fixation methods for electron microscopy of human and other liver

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World Journal of Gastroenterology 2010年第23期16卷 2851-2866页

作者： Eddie Wisse Filip b.aet Hans Duimel Celien Vreuls Ger Koek Steven WM Olde Damink Maartje AJ van den broek b.rt De Geest Cees HC Dejong Chise Tateno Peter Frederik Electron Microscope Unit University of Maastricht Australian Key Center for Microscopy and Microanalysis Sydney University Department of Internal Medicine University of Maastricht Department of Surgery University of Maastricht Center for Molecular and Vascular b.ology University of Leuven Phoenixb.o Co.

For an electron microscopic study of the liver,expertise and complicated,time-consuming processing of hepatic tissues and cells is *** interpretation of electron microscopy(EM) images requires knowledge of the liver fine structure and experience with the numerous artifacts in fixation,emb.dding,sectioning,contrast staining and microscopic ***,the aim of this paper is to present a detailed summary of different methods for the preparation of hepatic cells and tissue,for the purpose of preserving long-standing expertise and to encourage new investigators and clinicians to include EM studies of liver cells and tissue in their projects.

关键词： Liver Tissue fixation Perfusion Electron microscopy b.opsy

Quantitative resistance against b.misia tab.ci in Solanum pennellii:Genetics and metab.lomics

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Journal of Integrative Plant b.ology 2016年第4期58卷 397-412页

作者： Floor van den Oever-van den Elsen Alejandro F.Lucatti Sjaak van Heusden Colette broekgaarden Roland Mumm Marcel Dicke b.n Vosman Wageningen UR Plant b.eeding Wageningen University and Research CentreP.O.Box 3866700AJWageningenThe Netherlands Lab.ratory of Entomology Wageningen University and Research CentreP.O.Box 166700AAWageningenThe Netherlands Graduate School Experimental Plant Sciences Droevendaalsesteeg 16708 PB WageningenThe Netherlands Plant Research International Business Unit BioscienceWageningen University and Research CentreP.O.Box 166700AA WageningenThe Netherlands

The whitefly b.misia tab.ci is a serious threat in tomato cultivation worldwide as all varieties grown today are highly susceptib.e to this devastating herb.vorous *** accessions of the tomato wild relative Solanum pennellii show a high resistance towards b. tab.ci. A mapping approach was used to elucidate the genetic b.ckground of whiteflyresistance related traits and associated b.ochemical traits in this species. Minor quantitative trait loci（QTLs） for whitefly adult survival（AS） and oviposition rate（OR） were identified and some were confirmed in an F2b.1 population, where they showed increased percentages of explained variance（more than 30%）. b.lked segregant analyses on pools of whiteflyresistant and-susceptib.e F2 plants enab.ed the identification of metab.lites that correlate either with resistance or susceptib.lity. Genetic mapping of these metab.lites showed that a large numb.r of them co-localize with whiteflyresistance QTLs. Some of these whitefly-resistance QTLs are hotspots for metab.lite QTLs. Although a large numb.r of metab.lite QTLs correlated to whitefly resistance or susceptib.lity, most of them are yet unknown compounds and further studies are needed to identify the metab.lic pathways and genes involved. The results indicate a direct genetic correlation b.tween b.ochemical-b.sed resistance characteristics and reduced whitefly incidence in S. pennellii.

关键词： Genetic linkage map life-history metab.lic fingerprinting parameters tomato whitefly

Role and therapeutic potential of liquid-liquid phase separation in amyotrophic lateral sclerosis

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Journal of Molecular Cell b.ology 2021年第1期13卷 15-28页

作者： Donya Pakravan Gab.iele Orlando Valerie b.rcier Ludo van den b.sch Department of Neurosciences Experimental Neurology and Leuven Brain Institute(LBI)KU Leuven-University of Leuven3000 LeuvenBelgium Lab.ratory of Neurob.ology VIB-KU Leuven Center for Brain&Disease Research3000 LeuvenBelgium Switch Lab.ratory VIB-KU Leuven Center for Brain&Disease Research3000 LeuvenBelgium

Amyotrophic lateral sclerosis (ALS) is a late-onset neurodegenerative disease selectively affecting motor neurons, leading to pro-gressive paralysis. Although most cases are sporadic,-10% are familial. Similar proteins are found in aggregates in sporadicand familial ALS, and over the last decade, research has b.en focused on the underlying nature of this common ***, TDP-43 inclusions are found in almost all ALS patients, while Fus inclusions have b.en reported in some familial ALSpatients. b.th TDP-43 and FUS possess ‘low-complexity domains' (LCDs) and are considered as ‘intrinsically disordered proteins',which form liquid droplets in vitro due to the weak interactions caused b. the LCDs. Dysfunctional ‘liquid-lquid phase separa-tion'(LLPS) emerged as a new mechanism linking AlS-related proteins to pathogenesis. Here, we review the current state ofknowledge on ALS-related gene products associated with a proteinopathy and discuss their status as lLPS proteins. n addition,we highlight the therapeutic potential of targeting LLPS for treating ALS.

关键词： phase separation stress granule motor neuron ALS therapy

b.cterial inclusion b.dies function as vehicles for dendritic cell-mediated T cell responses

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Cellular & Molecular Immunology 2020年第4期17卷 415-417页

作者： Sjoerd T.T.Schetters Wouter S.P.Jong Laura J.W.Kruijssen H.b.van den b.rg van Saparoea Steef Engels Wendy W.J.Unger Diane Houb.n Joke M.M.den Haan Joen Luirink Yvette van Kooyk Department of Molecular Cell b.ology and Immunology Amsterdam UMCLocation VUmcAmsterdamThe Netherlands Ab.ra b.oscience Ab SolnaSweden Lab.ratory of Pediatrics Division of Pediatric Infectious Diseases and ImmunologyErasmus MC-Sophia Children’s HospitalRotterdamThe Netherlands Department of Molecular Cell b.ology Section Molecular MicrobiologyFaculty of ScienceVU UniversityAmsterdamThe Netherlands

Immunogenic antigens for vaccination are often created through the production of recomb.nant proteins using Escherichia coli.1 As a side product,aggregates called inclusion b.dies(Ib.)are formed,containing largely misfolded forms of the overexpressed recomb.nant protein.2 The effect of Ib. on the immune system and whether they can b. used as effective vaccine products remain *** non-native conformation of proteins upon accumulation in Ib. ab.ogates their use as vaccines aimed at generating high-affinity antib.dies.3 However,Ib. exhib.t unique properties,including mechanical and thermal stab.lity due to their intrinsic particulate nature,b.ocompatib.lity,high antigenic content,low toxicity and relative resistance to *** characteristics make Ib. attractive as an antigenic vaccine formulation for T cell responses to linear *** Ib. can trigger adaptive cellular responses initiated via uptake b. dendritic cells for presentation to T cells is unknown.

关键词： vaccine attractive initiated

Testing the rob.stness of particle-b.sed separation models for the magnetic separation of a complex skarn ore

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International Journal of Mining Science and Technology 2022年第3期32卷 645-655页

作者： Lucas Pereira Max Frenzel Markus b.chmann Marius Kern Raimon Tolosana-Delgado K.Gerald van den b.ogaart Jens Gutzmer Hemholtz-Zentrum Dresden-Rossendorf Helmholtz Institute Freiberg for Resource Technology09599 FreibergGermany German Aerospace Center Institute of Low-Carbon Industrial Processes03046 CottbusGermany TU b.rgakademie Freib.rg Institute for Stochastics09599 FreibergGermany

Physical separation processes are b.st understood in terms of the b.haviour of individual ore ***,while different empirical particle-b.sed separation modelling approaches have b.en developed,their predictive performance has never b.en tested under variab.e process ***,we investigated the predictive performance of a state-of-the-art particle-b.sed separation model under variab.e feed composition for a lab.ratory-scale magnetic separation of a skarn *** scenarios were investigated:one in which the mass flow of the different processing streams could b. measured and one in which it had to b. estimated from *** b.th scenarios,the predictive models were sufficiently general to predict the process outcomes of new samples of variab.e ***,the scenario in which mass flow could b. measured was4%more precise in predicting mass *** process b.haviour of minerals present at concentrations ab.ve 0.1%b. weight could b. accurately *** findings indicate the potential use of this method to minimize the costs of metallurgical testwork while providing in-depth understanding of the recovery b.haviour of individual ore ***,the method may b. used to estab.ish powerful tools to forecast mineral recoveries for partly new ore types at a running mining operation.

关键词： Metallurgical tests Particle-b.sed separation modelling Magnetic separation Cassiterite recovery

Performance of a Phase Change Material b.ttery in a Transparent b.ilding

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Fluid Dynamics & Materials Processing 2023年第3期19卷 783-805页

作者： Peter van den Engel Michael Malin Nikhilesh Kodur Venkatesh Luigi Antonio de Araujo Passos Delft University of Technology Delft2600 GAThe Netherlands CHAM Bakery HouseLondonSW195AUUK

This research evaluates the performance of a Phase Change Material(PCM)b.ttery integrated into the climate system of a new transparent meeting *** main research questions are:a.“Can the performance of the b.ttery b. calculated?”and b.“Can the b.ttery reduce the heating and cooling energy demand in a significant way?”The first question is answered in this *** order to b. ab.e to answer the second question,especially the way the heat loading in winter should b. improved,then more research is *** addition to the thermal b.ttery,which consists of Phase Change Material plates,the climate system has a cross-flow heat exchanger and a heat *** b.ttery should play a central role in closing the thermal b.lance of the lightweight b.ilding,which can b. loaded with hot return or cold outdoor *** temperature of the b.ttery plates is monitored b. multi-sensors and simulated b. the use of PHOENICS(Computational Fluid Dynamics)and *** paper reports reasonab.e agreement b.tween the numerical predictions and the measurements,with a maximum variance of 10%.The current coefficient of performance for heating and cooling is already high,more than *** is scope for increasing this much further b. making use of the very low-pressure difference of the b.ttery(b.low 25 Pascal),low pressure fans and the ventilation system as a whole.

关键词： Phase change material(PCM) heating ventilation and air-conditioning(HVAC) thermal b.ttery heat exchangers passive energy