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Current protocol to achieve dental movement acceleration and pain control with Photo-biomodulation

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World Journal of Methodology 2023年第5期13卷 379-383页

作者： angela Dominguez Department of Orthodontics Faculty of DentistryBenemerita Universidad Autónoma de PueblaZaragoza de Puebla Calle 4 Sur 104PueblaC.P.72000Mexico

When designing a study on dental movement acceleration or pain control during orthodontic treatment,it is crucial to consider effective *** objective of this editorial is to compile the most effective parameters supported by evidence that should be considered in future studies to achieve complete parameter *** protocol currently recommended to homogenize the parameters and facilitate the development of further meta-analysis in terms of acceleration of movement and pain control in orthodontics is Wavelength:810 nm,2.2 J per surface,0.1 W in continuous mode/0.1 W average power in a superpulsed,sweeping movement,1mm from the mucosa,22 seconds along the vestibular surface and 22 seconds along the lingual surface,the recommended speed of movement is 2 mm/sec,1 application during each orthodontic control,to achieve dental movement acceleration and repeat the dose at 24 h to ensure pain *** energy density and power density will depend on the spot size used in the equipment and the distance from the *** will strengthen the evidence of photobiomodulation as the best therapy to accelerate tooth movement and at the same time control the pain produced by orthodontic treatments.

关键词： Photobiomodulation Laser-assisted orthodontics Dental movement acceleration Pain control Diode laser

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A Brighter Path

China Forex 2022年第4期 50-52页

作者： angela LIU 不详

2022 has been an eventful and volatile *** the many challenges the market has faced and will continue to face,material progress has been made in China's financial reform *** look forward to a brighter 2023 with optimism.

关键词： financial spite continue

In vitro and in vivo models of acute alcohol exposure

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World Journal of Gastroenterology 2009年第10期15卷 1168-1177页

作者： angela Dolganiuc Gyongyi Szabo Department of Medicine University of Massachusetts Medical School 364 Plantation Street Worcester MA 01605-2324 United States

Alcohol abuse is a global problem due to the financial burden on society and the healthcare system. While the harmful health effects of chronic alcohol abuse are well established, more recent data suggest that acute alcohol consumption also affects human wellbeing. Thus, there is a need for research models in order to fully understand the effect of acute alcohol abuse on different body systems and organs. The present manuscript summarizes the interdisciplinary advantages and disadvantages of currently available human and non-human models of acute alcohol abuse, and identifi es their suitability for biomedical research.

关键词：急性酒精中毒体内模型卫生保健系统体外酒精滥用全球性问题财政负担酒精消费

Nanostructured biohybrid material with wide-ranging antiviral action

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Nano Research 2023年第8期16卷 11455-11463页

作者： Noelia Losada-Garcia angela Vazquez-Calvo David Ortega-Alarcon Olga Abian Adrian Velazquez-Campoy Pilar Domingo-Calap Antonio Alcami Jose M.Palomo Instituto de Catálisis y Petroleoquímica(ICP) CSICC/Marie Curie 2.Madrid 28049Spain Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas(CSIC)-Universidad Autónoma de Madrid(UAM)Madrid 28049Spain Institute of Biocomputation and Physics of Complex Systems(BIFI) Joint Unit GBsC-CSIC-BIFIUniversity of ZaragozaZaragoza 50018Spain Fundación Instituto de Investigación Sanitaria de Aragón(IIS Aragón) Zaragoza 50009Spain CIBERehd Madrid 28029Spain Instituto de Biología Integrativa de Sistemas I2SyBioUniversitat de València-CSICValència E-46071Spain

Respiratory pathogens kill more people than any other infectious agent each year *** of novel,economically friendly,sustainable,and highly efficient materials against viruses is a major ***,we describe a nanostructured material composed of very small crystalline phosphate copper nanoparticles synthesized using a new biohybrid technology that employs a biological agent for its formation at room temperature in aqueous *** evaluation of different enzymes in the final preparation of the nanomaterial or even in synthetic methods was *** characterization revealed the formation of Cu species in the protein *** best biomaterial synthesized using a lipase called BioCuNPs showed excellent inhibition capacity against functional proteins of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2);for example,assent 3-chymotrypsin like protease(3CLpro)complete inhibition was achieved by using 5µg/mL,or acetone(ACE)–spike protein interaction was inhibited by more than 80%in the presence of 400µg/mL of *** these in vitro results into account,an efficacy analysis against human coronavirus 229E(HCoV-E229)coronavirus was performed.A virus reduction of 99%was obtained in 5 ***,SARS-CoV-2 virus was tested to demonstrate high efficiency,with>99%inhibition in 15 min using 500 microgram of *** determine the wide applicability of this nanohybrid against viruses,an evaluation was carried out against a non-enveloped virus such as Human Rhinovirus(HRV-14),obtaining a virus reduction of 99.9%in 5 ***,the virucidal capacity against different bacteriophages was also evaluated,obtaining an excellent inhibition effect against PhageΦX174(99.999%reduction in 5 min).

关键词： antiviral compound coronaviruses copper nanoparticles nanobiotechnology viruses

Small is beautiful–a glycolytic metabolite signals mTORC1 activation in cancer cell metabolism

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Signal Transduction and Targeted Therapy 2020年第1期5卷 299-300页

作者： angela M.Otto Munich Institute of BioEngineering Technical University of Munich85748 GarchingGermany

Even though the mTOR complex has been known for decades as a nutrient sensor,being thus in focus for drug targeting in metabolic disease and cancer metabolism,it has remained puzzling how it is able to get a sense of glucose availability in ***,a small metabolite of the glycolytic pathway,dihydroxyacetone phosphate,has been identified by Sabatini and his coworkers,who show how mTORC1-activity is regulated in glucose-starved and replenished cancer cells.

关键词： metabolism cancer mTORC1

How Africa Is Promoting Agricultural Innovations and Technologies amidst the COVID-19 Pandemic

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Molecular Plant 2020年第10期13卷 1345-1346页

作者： angela Joseph Fernando Consultant-The Alliance of Bioversity International and CIAT Km 17 Recta Cali-PalmiraApartado Aéreo 6713763537 CaliColombia

The COVID-19 pandemic has left an indelible mark on Africa's Agribusiness *** of households whose livelihoods depend on farming are facing a huge food *** mitigate these effects,the African Agricultural Technology Foundation(AATF)gathered a panel of renowned agricultural experts through an interactive webinar themed"Promotion of Agricultural Technologies and Innovations for Agri-Business Resilience in Africa in the Wake of COVID-19",the first in a series of several interactive seminars to be held virtually until the end of December *** seminars will focus on several topics specific to agricultural transformation,which revolve around smallholder farmers in Sub-Saharan Africa(SSA)and aim to help them come out of the cataclysmic effect of COVID-19 and recover their business and livelihoods.

关键词： Agricultural Africa interactive

Rational design of platinum(Ⅱ)complexes with orthogonally oriented triazolyl ligand with emission enhancement characteristics for cancer chemotherapy in vivo

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Science China Chemistry 2023年第10期66卷 2878-2884页

作者： Yeye Ai Zherui Zhang Yuexuan Fei Ruirong Ye angela Sin-Yee Law Zong-Wan Mao Junqiu Liu Yongguang Li Vivian Wing-Wah Yam Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education College of Material Chemistry and Chemical EngineeringHangzhou Normal UniversityHangzhou 311121China Institute of Molecular Functional Materials State Key Laboratory of Synthetic Chemistry and Department of ChemistryThe University of Hong KongHong KongChina School of Chemistry Sun Yat-Sen UniversityGuangzhou 510275China State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun 130012China

The mitochondria are essential for tumorigenesis and have been regarded as important targets in cancer ***,the mitochondria-targeted platinum(Ⅱ)complexes have been *** introduction of the triazole group with larger steric hindrance through post-click reaction converts the hybridization of carbon from sp to sp^(2),endowing the complexes with an orthogonally oriented ligand with restricted rotation and emission enhancement *** of the triazolyl ligand has led to platinum(Ⅱ)complexes that can efficiently enter cancer cells and selectively accumulate in mitochondria,leading to significant enhancement in *** vivo anti-cancer investigations have demonstrated their distinct antitumor efficacy in substantial inhibition of tumor growth in breast cancer mice through dissipation of mitochondrial membrane potential,inducing apoptosis of tumor cell with negligibly systemic cytotoxicity.

关键词： platinum(Ⅱ)complexes post-click reaction emission enhancement mitochondria-targeting antitumor

The role of interstitial species upon the ammonia synthesis activity of ternary Fe–Mo–C(N) and Ni–Mo–C(N) phases

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Journal of Energy Chemistry 2019年第12期28卷 170-175页

作者： angela Daisley Justin S.J.Hargreaves WestCHEM School of Chemistry University of Glasgow

Fe3Mo3C has been prepared and its activity for ammonia synthesis was *** had been observed previously for Co3Mo3C,it was found to be inactive at 400℃.At 500℃activity developed and this can be related to the substitution of lattice carbon by *** of a simple topotactic route to prepare Ni2Mo3C from Ni2Mo3N proved unsuccessful,with the resultant carbonitride formed under optimal synthesis conditions being active for ammonia synthesis at 400℃.

关键词： Nitride Carbide Carbonitride Ammonia Nickel Iron Molybdenum

Incorporating the mutational landscape of SARS-COV-2 variants and case-dependent vaccination rates into epidemic models

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Infectious Disease Modelling 2022年第2期7卷 75-82页

作者： Mohammad Mihrab Chowdhury Md Rafiul Islam Md Sakhawat Hossain Nusrat Tabassum angela Peace Department of Mathematics and Statistics Texas Tech UniversityLubbockTXUSA Department of Mathematics Iowa State UniversityAmesIAUSA

Coronavirus Disease(COVID-19),which began as a small outbreak in Wuhan,China,in December 2019,became a global pandemic within months due to its high *** the absence of pharmaceutical treatment,various non-pharmaceutical interventions(NPIs)to contain the spread of COVID-19 brought the entire world to a *** almost a year of seemingly returning to normalcy with the world's quickest vaccine development,the emergence of more infectious and vaccine resistant coronavirus variants is bringing the situation back to where it was a year *** the light of this new situation,we conducted a study to portray the possible scenarios based on the three key factors:impact of interventions(pharmaceutical and NPIs),vaccination rate,and vaccine *** our study,we assessed two of the most crucial factors,transmissibility and vaccination rate,in order to reduce the spreading of COVID-19 in a simple but effective *** order to incorporate the time-varying mutational landscape of COVID-19 variants,we estimated a weighted transmissibility composed of the proportion of existing strains that naturally vary over ***,we consider time varying vaccination rates based on the number of daily new *** method for calculating the vaccination rate from past active cases is an effective approach in forecasting probable future scenarios as it actively tracks people's attitudes toward immunization as active case *** simulations show that if a large number of individuals cannot be vaccinated by ensuring high efficacy in a short period of time,adopting NPIs is the best approach to manage disease transmission with the emergence of new vaccine breakthrough and more infectious variants.

关键词： Break-through variants Waning immunity Reinfection Non-pharmaceutical interventions(NPIs) Vaccination rate