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患弥漫性糖尿病性黄斑水肿患者行吲哚青绿辅助性内界膜剥离的玻璃体切割术后视神经萎缩

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世界核心医学期刊文摘（眼科学分册） 2005年第5期1卷 38-39页

作者： ando f. Yasui O. Hirose H. Ohba N. 秦雪娇 EyeCare Nagoya Meieki 3-13-15 Nakamura-ku 450-0002 Nagoya Japan

Purpose: To report anatomic and visual outcomes of.vitrectomy and indocyanine green (ICG)-assisted peeling of.the retinal internal limiting membrane (ILM) in the treatment of.dif.use diabetic macular edema. Methods: In a retrospective in terventional case series, 15 eyes of.11 patients with ref.actory dif.use diabeti c macular edema underwent pars plana vitrectomy with removal of.the ILM, which w as stained by intravitreal injection of.ICG (0.1-0.2 ml of.0.5%ICG), perf.rmed by a single surgeon. The patients were f.llowed up f.r 14-28 months (mean 20.5 months). The main outcome measures were assessment of.macular edema by optical coherence tomography and determination of.visual acuity and visual f.eld. Result s: Intravitreal ICG visualized the ILM to f.cilitate complete removal of.the str ucture. Qualitative assessment of.optical coherence tomography images at the end of.f.llow-up revealed that retinal thickness in the macula appeared nearly nor mal with or without reappearance of.f.veal pit in 11 of.the 15 eyes (73.3%), de creased in 3 eyes (20.0%), and did not change in 1 eye (6.6%). Best-corrected visual acuity at the end of.f.llow-up improved by 2 lines or more in 4 eyes (2 6.7%), virtually unchanged in 6 eyes (40.0%), and deteriorated by 2 lines or m ore in 5 eyes (26.7%). The mean logMAR visual acuity was 0.680 (approximately 1 2/60) preoperatively and 0.812 (approximately 9/60) postoperatively, the dif.ere nce being not statistically signif.cant (paired t-test, P=0.445). Seven (46.7% ) of.the 15 eyes developed optic nerve atrophy that occurred gradually within 6 months af.er surgery and caused irreversible peripheral visual f.eld def.ct pred ominantly af.ecting the nasal f.eld. Conclusion: Intravitreal application of.ICG is benef.cial in uneventf.l ILM peeling to help resolution of.dif.use diabetic macular edema, but it may potentially damage the optic nerve f.bers and lead to unf.vorable visual outcomes.

关键词：内界膜剥离玻璃体切割术视神经萎缩吲哚青绿玻璃体腔弥漫性黄斑水肿睫状体平坦部黄斑中心凹视功能

Characterization of.conception drawing in architecture to f.ce technological mediations

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f.ontiers of.Architectural Research 2024年第3期13卷 425-438页

作者： Hugo C.Gomez-Tone Javier f.Raposo Grau Departamento de Ideación Gráf.ca Arquitectónica Universidad Politécnica de MadridMadrid 28040Spain Departamento de Arquitectura Universidad Nacional de San Agustín de ArequipaArequipa 04001Peru

The conception drawing in architecture is that allows to initiate the architectural thinking,visualizing,and discovering the f.rst *** drawing has traditionally been given as an act of.linking and collaboration between thought,sight,and the movement of.the hands with a *** and recognizing its characteristics will make it possible to deal with any mediation of.inf.rmation *** establish such characteristics,three case studies were carried *** analysis was made of.the conception drawings and interviews by the Pritzker Prize laureates:ando,Hadid and *** condition and f.ur characteristics have been determined:drawing is a phenomenological action that produces haptic drawings;it is an undecided process that originates unf.rmed drawings;it is a f.st action that results in small and multiplied drawings;it is a perceptual act that generates redrawn and remarked drawings;and f.nally,it is an action that seeks to remember to resume the creative process at another moment,which produces rudimentary conventional *** these bef.re any technological mediation will be an important pedagogical contribution that will allow f.ture architects not to alter the cognitive processes that generate the f.rst ideas in the initial moments of.the architectural project.

关键词： Conception drawing Architectural thinking Graphic ideation Concept Creativity

Identif.cation of.an intronic enhancer regulating RANKL expression in osteocytic cells

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骨研究:英文版 2023年第3期11卷 607-616页

作者： Minglu Yan Masayuki Tsukasaki Ryunosuke Muro Yutaro ando Kazutaka Nakamura Noriko Komatsu Takeshi Nitta Tadashi Okamura Kazuo Okamoto Hiroshi Takayanagi Department of.Immunology Graduate School of Medicine and Faculty of MedicineThe University of TokyoTokyoJapan Department of.Osteoimmunology Graduate School of Medicine and Faculty of MedicineThe University of TokyoTokyoJapan Department of.Microbiology Tokyo Dental CollegeTokyoJapan Department of.Oral and Maxillof.cial Surgery Department of Sensory and Motor System MedicineGraduate School of MedicineThe University of TokyoTokyoJapan Department of.Laboratory Animal Medicine Research InstituteNational Center for Global Health and MedicineTokyoJapan

The bony skeleton is continuously renewed throughout adult lif. by the bone remodeling process,in which old or damaged bone is removed by osteoclasts via largely unknown *** regulate bone remodeling by producing the osteoclast dif.erentiation f.ctor RANKL(encoded by the TNf.f.1 gene).However,the precise mechanisms underlying RANKL expression in osteocytes are still ***,we explored the epigenomic landscape of.osteocytic cells and identif.ed a hitherto-undescribed osteocytic cell-specif.c intronic enhancer in the TNf.f.1 gene *** analyses showed that transcription f.ctors involved in cell death and senescence act on this intronic enhancer ***-cell transcriptomic data analysis demonstrated that cell death signaling increased RANKL expression in osteocytic *** deletion of.the intronic enhancer led to a high-bone-mass phenotype with decreased levels of.RANKL in osteocytic cells and osteoclastogenesis in the adult stage,while RANKL expression was not af.ected in osteoblasts or *** data suggest that osteocytes may utilize a specialized regulatory element to f.cilitate osteoclast f.rmation at the bone surf.ce to be resorbed by linking signals f.om cellular senescence/death and RANKL expression.

关键词： utilize removed linking

Look into my eyes:What can eye-based measures tell us about the relationship between physical activity and cognitive perf.rmance?

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Journal of.Sport and Health Science 2023年第5期12卷 568-591页

作者： Liye Zou f.bian Herold Sebastian Ludyga Keita Kamijo Notger G.Muller Matthew B.Pontif.x Matthew Heath Ryuta Kuwamizu Hideaki Soya Charles H.Hillman Soichi ando Brandon L.Alderman Boris Cheval Arthur f.Kramer Body-Brain-Mind Laboratory School of PsychologyShenzhen UniversityShenzhen 518060China Research Group Degenerative and Chronic Diseases MovementFaculty of Health Sciences BrandenburgUniversity of PotsdamPotsdam 14476Germany Department of.Sport Exerciseand HealthUniversity of BaselBasel 4052Switzerland f.culty of.Liberal Arts and Sciences Chukyo UniversityNagoya 466-8666Japan Department of.Kinesiology Michigan State UniversityEast LansingMI 48824USA School of.Kinesiology Faculty of Health SciencesUniversity of Western OntarioLondon ON N6A 3K7Canada Canadian Centre f.r Activity and Aging University of Western OntarioLondon ONN6A 3K7Canada Graduate Program in Neuroscience University of Western OntarioLondon ONN6A 3K7Canada Laboratory of.Exercise Biochemistry and Neuroendocrinology Faculty of Health and Sport SciencesUniversity of TsukubaTsukuba 305-0006Japan Sport Neuroscience Division Advanced Research Initiative for Human High Performance(ARIHHP)Faculty of Health and Sport SciencesUniversity of TsukubaTsukuba 305-0006Japan Center f.r Cognitive and Brain Health Department of PsychologyDepartment of Physical TherapyMovementand Rehabilitation SciencesNortheastern UniversityBostonMA 02115USA Graduate School of.Inf.rmatics and Engineering The University of Electro-CommunicationsTokyo 182-8585Japan Department of.Kinesiology and Health Rutgers UniversityNew BrunswickNew BrunswickNJ 08854USA Swiss Center f.r Af.ective Sciences University of GenevaGeneva 1205Switzerland Laboratory f.r the Study of.Emotion Elicitation and Expression(E3Lab) Department of PsychologyUniversity of GenevaGeneva 1205Switzerland Department of.Psychology Center for Cognitive and Brain HealthNortheastern UniversityBostonMA 02115USA Beckman Institute University of Illinois at Urbana-ChampaignChampaignIL 61820USA

Background:There is a growing interest to understand the neurobiological mechanisms that drive the positive associations of.physical activity and f.tness with measures of.cognitive *** better understand those mechanisms,several studies have employed eye-based measures(e.g., eye movement measures such as saccades,pupillary measures such as pupil dilation,and vascular measures such as retinal vessel diameter)deemed to be proxies f.r specif.c neurobiological ***,there is currently no systematic review providing a comprehensive overview of.these studies in the f.eld of.exercise-cognition ***,this review aimed to address that gap in the ***:To identif. eligible studies,we searched 5 electronic databases on October 23,*** researchers independently extracted data and assessed the risk of.bias using a modif.ed version of.the Tool f.r the assEssment of.Study qualiTy and reporting in EXercise(TESTEX scale,f.r interventional studies) and the critical appraisal tool f.om the Joanna Briggs Institute(f.r cross-sectional studies).Results:Our systematic review(n=35 studies) of.ers the f.llowing main f.ndings:(a) there is insuf.icient evidence available to draw solid conclusions concerning gaze-f.xation-based measures;(b) the evidence that pupillometric measures,which are a proxy f.r the noradrenergic system,can explain the positive ef.ect of.acute exercise and cardiorespiratory f.tness on cognitive perf.rmance is mixed;(c) physical training-or f.tness-related changes of.the cerebrovascular system(operationalized via changes in retinal vasculature) are,in general,positively associated with cognitive perf.rmance improvements;(d) acute and chronic physical exercises show a positive ef.ect based on an oculomotor-based measure f.nction(operationalized via antisaccade tasks);and(e) the positive association between cardiorespiratory f.tness and cognitive perf.rmance is partly mediated by the dopaminergic system(operationalized via spo

关键词： Cognition Exercise f.tness Pupil size RetinaTagedAPTARAEnd

PROMISING f.ST REACTOR SYSTEMS IN THE f.ASIBILITY STUDY ON COMMERCIALIZED f. CYCLE SYSTEMS

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PROMISING FAST REACTOR SYSTEMS IN THE FEASIBILITY STUDY ON C...

Solid-State NMR Analysis of.Irradiated f.uoropolymers

第十三届国际核工程大会

作者： Yoshihiko Sakamoto Shoji Kotake Akira Nishikawa Yasuhiro Enuma Masato ando Yutaka Sagayama Japan Nuclear Cycle Development Institute(JNC) The Japan Atomic Power Company Co. Ltd.(JAPC)

The f.asibility Study on Commercialized f.st Reactor Cycle Systems(f.S) is under progress in order to propose prominent f.st Reactor(f.) cycle systems that will respond to the diverse needs of.soci

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Solid-State NMR Analysis of Irradiated Fluoropolymers

绿脓假单胞菌肺炎和巨细胞病毒肺炎的HRCT表现对比

RadTech Asia 2005

作者： Yukari Numata Akihiro Oshima Keitaro Aimi Shinji ando Katsuyoshi Murata Hiroyuki Kono Masakazu Washio Etsuko Katoh Department of.Biochemistry National Institute of Agrobiological Science （NIAS） 2-1-2 Kannondai Tsukuba Ibaraki 305-8602Japan Advanced Research Institute f.r Science and Engineering Waseda University 3-4-1 Okubo Shinjuku-ku Tokyo 169-8555Japan Department of.Organic and polymeric Materials Tokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo152-8552 Japan Department of.Organic and polymeric Materials Tokyo Institute of Technology 2-12-1 Ookayama Meguro-ku Tokyo152-8552 Japan Department of.Biochemistry National Institute of Agrobiological Science （NIAS） 2-1-2 Kannondai Tsukuba Ibaraki 305-8602 Japan Bruker BioSpin Company Ltd. Ninomiya 3-21-5 Tsukuba Ibaraki 305-0051 Japan Advanced Research Institute f.r Science and Engineering Waseda University 3-4-1 Okubo Shinjuku-ku Tokyo 169-8555Japan Department of.Biochemistry National Institute of Agrobiological Science （NIAS） 2-1-2 Kannondai Tsukuba Ibaraki 305-8602Japan

＜正＞ We have investigated changes in chemical structures and molecular dynamics f.r electron beam（EB）-irradiated MPE/PTf. polymer-blend using solid-state NMR spectroscopy. Although 13the 13C MAS NMR spectra did not yield usef.l inf.rmation regarding changes in the chemical structure of.MPE/PTf. by the EB- irradiation, it was possible to obtain detailed structural inf.rmation f.om the 19f.MAS NMR spectra. The results indicate that 19f.signals at -215 （-Cf.- and/or -Cf.2） and -140 ppm （-Cf.H） f.r EB-irradiated MPE/PTf. are characteristic signals, which are not observed in independently irradiated PTf.. f.rthermore, relaxation times f.r these samples were measured, and the results indicate that the molecular motion of.the crystalline components of.PTf. and MPE is altered by EB-irradiation. These NMR experimental results indicate that a chemical reaction occurred between MPE and PTf., and that their molecular motion was signif.cantly changed by irradiation.

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国际医学放射学杂志 2015年第1期 100-101页

作者： A.K.Omeri f.Okada S.Takata A.Ono T.Nakayama Y.ando Department of.Radiology Oita University Faculty of Medicine

目的比较绿脓假单胞菌肺炎和巨细胞病毒肺炎病人肺部的HRCT表现。方法 124例绿脓假单胞菌肺炎病人（男77例,女47例;年龄20;9岁,平均65.4岁）和44例

关键词：巨细胞病毒肺炎绿脓假单胞菌肺部病人 HRCT 铺路石征

Dif.erentiations of.geographic distribution and subsistence strategies between Tibetan and other major ethnic groups are determined by the physical environment in Hehuang Valley

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Science China Earth Sciences 2019年第2期62卷 412-422页

作者： Xin JIA Harry f.LEE Mengchun CUI Guoquan CHENG Yang ZHAO Hong DING Ricci P.H.YUE Huayu LU School of.Geographic and Oceanographic Sciences Nanjing University College of.Earth and Environmental Sciences Lanzhou University Needham Research Institute Department of.Geography and Resource Management The Chinese University of Hong Kong School of.Marxism Taiyuan University of Technology Department of.Geography and International Center f.r China Development Studies The University of Hong Kong

The people of.the Tibetan Plateau have received extensive attention f.om scholars because of.their unique adaptability to the low temperature and anoxic environments. However, the Tibetan communities and their habitats in the low-altitude regions of.the plateau have rarely been studied in a scientif.c manner. Based on the extraction of.geographic inf.rmation of.197 towns in the Hehuang Valley and on variance analysis, this study examines the habitats and subsistence strategies of.the Tibetans and other major ethnic groups in the low-latitude region of.the Tibetan Plateau. Our statistical results show that the annual average temperature of.Tibetan habitats in the Hehuang Valley is relatively high. The relatively warm environment of.the valley allows the Tibetans in that area to cultivate wheat and barley and raise cattle and sheep—a subsistence strategy signif.cantly dif.erent f.om that of.other Tibetans in the high-altitude regions in the Tibetan Plateau. In addition, the Tibetan communities in the Hehuang Valley include similar agri-pastoral ethnic groups (including Hui and Salar), both of.which adopt similar subsistence strategies. The agricultural ethnic groups (Han and Tu) live in a relatively cool and humid environment f.cilitating agricultural production, while the agri-pastoral ethnic groups (Tibetan, Hui, and Salar) inhabit relatively warm and arid environment in the valley. Due to the lack of.agricultural activities, agri-pastoral groups must also engage in animal husbandry to supplement their diet. In the ando Tibetan region, the subsistence strategies of.the ethnic groups are closely related to their physical *** ethnic groups communicate among themselves, integrate, and inf.uence each other, resulting in a diversif.ed culture. This study proves that the habitat variation at a regional scale corresponds signif.cantly to the variation of.subsistence strategies. Our f.ndings may f.rther ref.ne knowledge about the human-environmental relationsh

关键词： Tibetan Plateau Ethnic group Ethnic geography Hehuang Valley ando Tibetan region

用纳滤膜分离混合无机电解质溶液的性能评价方法

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化工学报 2007年第3期58卷 673-678页

作者：王大新廖卓丹伍灵王晓琳富康博安藤雅明新谷卓司清华大学化学工程系北京100084 日东电工株式会社

提出一个新的混合无机电解质溶液的纳滤膜分离性能的评价方法。该评价方法将纳滤膜分离性能表述为某种离子在膜中的透过率,其值与混合电解质总浓度、各种离子的当量分数和同号离子之间通过纳滤膜的竞争作用有关。首先根据一些双组分无... 详细信息

提出一个新的混合无机电解质溶液的纳滤膜分离性能的评价方法。该评价方法将纳滤膜分离性能表述为某种离子在膜中的透过率,其值与混合电解质总浓度、各种离子的当量分数和同号离子之间通过纳滤膜的竞争作用有关。首先根据一些双组分无机电解质溶液的纳滤膜分离实验获得离子的竞争系数,然后采用几种不同组成不同浓度的混合电解质溶液(NaCl和Naf.NaCl和KCl;Naf.NaCl和NaNO3;NaCl、NaNO3和Na2SO4;Naf.NaCl、NaNO3和Na2SO4)通过ESNA1膜的透过实验验证该评价方法的适用性。结果表明混合电解质溶液总浓度和离子的当量分数是影响各种离子通过纳滤膜的表观透过率的主要因素,评价方法预测值与实验数据相符合。说明该方法适用于评价含有单价阳离子的混合无机电解质溶液的纳滤膜分离性能。

关键词：膜分离纳滤混合电解质评价方法透过率