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The linear self-attracting diffusion driven by the weighted-fractional Brownian motion II: The parameter estimation

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Science China Mathematics 2025年

作者： Litan yan Rui Guo wenyi Pei Department of Statistics College of Science Donghua University School of Statistics and Mathematics Zhejiang Gongshang University

Let Ba,bbe a weighted-fractional Brownian motion with Hurst indexes a and b such that a>-1and 0≤b<1∧（1+a）.In this paper,we consider the linear self-attracting diffusion ■ interacting diffusion (see Cranston and L...

Let Ba,bbe a weighted-fractional Brownian motion with Hurst indexes a and b such that a>-1and 0≤by asymptotic ■ converges in distribution to the sum of the chi-square random variable with 1 degree of freedom and the random variable Z1a,b.

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Actinidia deliciosa as a complemental therapy against nephropathy and oxidative stress in diabetic rats

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Food Science and Human Wellness 2023年第6期12卷 1981-1990页

作者： ali y.naoom.wenyi kang Nora F.Ghanem Mohamed M.Abdel-Daim Fatma M.El-Demerdash Department of Medical Laboratory Techniques Imam Ja'afar Al-Sadiq UniversityAl-Muthanna 66002Iraq National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Department of Zoology Faculty of ScienceKafr ElSheikh UniversityKafr El Sheikh 33516Egypt Department of Pharmaceutical Sciences Pharmacy ProgramBatterjee Medical CollegeJeddah 21442Saudi Arabia Pharmacology Department Faculty of Veterinary MedicineSuez Canal UniversityIsmailia 41522Egypt Department of Environmental Studies Institute of Graduate Studies and ResearchAlexandria UniversityAlexandria 21526Egypt

This study aimed to evaluate the anti-hyperglycemic and antioxidant role of Actinidia deliciosa(kiwifruits)aqueous extract in streptozotocin-treated *** were distributed into;control,*** aqueous extract(ADAE;1 g/kg orally),streptozotocin(STZ;50 mg/kg,i.p,single dose),and STZ plus ADAE,*** showed that ADAE had high antioxidant and radical scavenging *** in blood sugar level,lipid peroxidation(LPO),kidney function biomarkers,and perturbations in hematological parameters were observed in diabetic ***,enzymatic and non-enzymatic antioxidants,protein content,and alkaline phosphatase(ALP)activity ***,histological,immunohistochemical alpha-smooth muscle actin immunoreactivity(α-SMA-ir)and histochemical(collagen,total protein,DNA,and RNA)alterations were observed in rat ***,STZ produced upregulation of inflammatory associated genes(tumor necrosis factor-alpha;TNF-αand transforming growth factorβ1;TGF-β1)and triggered apoptosis by upregulating apoptotic related gene[Bcl2-associated X protein(Bax)]and downregulating anti-apoptotic related gene B-cell lymphoma-2(Bcl-2)based on real-time PCR ***,diabetic rats administered with ADAE showed significant restoration in LPO,antioxidant status,and biochemical indices besides tissue architecture,and genes improvement regarding STZ ***,*** has a valuable ameliorative infl uence and can restore glucose levels and improve kidney dysfunction in diabetic rats.

关键词： Diabetes mellitus Actinidia deliciosa Inflammation Apoptosis Oxidative stress Nephropathy

基于非靶向代谢组学分析甲基化对副干酪乳酪杆菌发酵剂贮藏特性的影响

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食品科学 2025年第1期46卷 49-55页

作者：游明坤张文羿内蒙古农业大学乳品生物技术与工程教育部重点实验室内蒙古呼和浩特010018

副干酪乳酪杆菌(Lacticaseibacillus paracasei)Zhang是一株具有调节免疫反应、抗氧化等益生特性的优良菌株。DNA甲基化是一种重要的表观遗传机制,在细菌的很多生理过程中发挥关键作用。为更好利用该菌株,本研究重点关注甲基化对*** Zh... 详细信息

副干酪乳酪杆菌(Lacticaseibacillus paracasei)Zhang是一株具有调节免疫反应、抗氧化等益生特性的优良菌株。DNA甲基化是一种重要的表观遗传机制,在细菌的很多生理过程中发挥关键作用。为更好利用该菌株,本研究重点关注甲基化对*** Zhang发酵剂贮藏特性的影响。利用*** Zhang及其DNA甲基化突变株ΔpglX制备发酵剂并在30℃条件下贮藏90 d。结果表明:与野生型相比,甲基化突变株在贮藏90 d后活菌数极显著提高(P<0.01);利用非靶向代谢组学方法分析贮藏90 d后野生型及其甲基化突变体的代谢物差异发现,与野生型相比,突变体的差异代谢物质有269种,在负离子模式下主要富集到核苷酸代谢、嘌呤代谢、嘧啶代谢、柠檬酸循环、乙醛酸盐和二羧酸盐代谢等多条代谢通路,在正离子模式下主要富集到生物素代谢等多条代谢通路。研究结果证实DNA甲基化可以通过生成和利用碳水化合物类、脂肪酸类物质等提高*** Zhang的贮藏特性。

关键词：副干酪乳酪杆菌 DNA甲基化贮藏特性发酵剂 pglX 非靶向代谢组学

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渗透树脂联合美白技术修复微裂氟斑牙

中国组织工程研究 2025年第4期29卷 686-691页

作者：张文怡尹昭张健天津医科大学口腔医院修复科天津市300070 衡水市第四人民医院河北省衡水市053000 天津医科大学口腔医院口腔颌面外科天津市300070

背景:微研磨、家庭美白联合渗透树脂治疗氟斑牙具有良好的效果,但该方法对氟斑牙微裂纹的影响尚不清楚。目的:探究微研磨、家庭美白联合渗透树脂修复微裂氟斑牙的效果。方法:①临床研究:选择2020年7月至2021年3月就诊于天津医科大学口... 详细信息

背景:微研磨、家庭美白联合渗透树脂治疗氟斑牙具有良好的效果,但该方法对氟斑牙微裂纹的影响尚不清楚。目的:探究微研磨、家庭美白联合渗透树脂修复微裂氟斑牙的效果。方法:①临床研究:选择2020年7月至2021年3月就诊于天津医科大学口腔医院修复科的23例微裂氟斑牙患者,包括255颗微裂氟斑牙,均接受牙齿微研磨术、家庭美白与渗透树脂联合治疗,对比治疗前及治疗结束后1周、1个月的牙齿颜色、牙齿敏感程度和牙齿疼痛阈值。②体外实验:收集牙齿表面至少存在一条裂纹的氟斑牙60颗,随机分3组处理:对照组不进行任何处理,美白组进行微研磨与家庭美白处理,联合组进行微研磨、家庭美白和渗透树脂联合处理,每组20颗,测量处理后3组牙齿样本的显微硬度。结果与结论:①临床研究:治疗结束后6个月,255颗微裂氟斑牙中牙齿美白治疗显效207颗、有效48颗,总体治疗有效率为100%。随着治疗时间的延长,中、重度牙齿度敏感程度占比呈下降趋势,治疗结束后6个月,255颗氟斑牙中无重度敏感、15颗为中度敏感、125颗为轻度敏感、115颗无敏感,与治疗前的氟斑牙敏感程度相比差异有显著性意义(P0.05)。②体外实验:美白组牙齿显微硬度值低于对照组、联合组(P0.05)。③结果表明,微研磨、家庭美白联合渗透树脂治疗微裂氟斑牙具有较好的疗效。

关键词：氟斑牙微裂纹渗透树脂牙齿美白治疗效果显微硬度

Thermo-Mechanically Coupled Thermo-Elasto-Visco-Plastic Modeling of Thermo-Induced Shape Memory Polyurethane at Finite Deformation

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Acta Mechanica Solida Sinica 2018年第2期31卷 141-160页

作者： Jian Li Qian-hua Kan Ze-bin Zhang Guo-zheng kang wenyi yan State Key Laboratory of Traction Power Southwest Jiaotong University Applied Mechanics and Structure Safety Key Laboratory of Sichuan Province School of Mechanics and EngineeringSouthwest Jiaotong University Department of Mechanical and Aerospace Engineering Monash University

A series of monotonic tensile experiments of thermo-induced shape memory polyurethane （TSMPU） at different loading rates were carried out to investigate the interaction between the internal heat production and the mechanical deformation. It is shown that the tem- perature variation on the surfaces of the specimens due to the internal heat production affects the mechanical properties of TSMPU remarkably. Then, based on irreversible thermodynamics, the Helmholtz free energy was decomposed into three parts, i.e., the instantaneous elastic free energy, visco-plastic free energy and heat free energy. The total deformation gradient was decomposed into the mechanical and thermal parts, and the mechanical deformation gradient was further divided into the elastic and visco-plastic components. The Hencky＇s logarithmic strain was used in the current configuration. The heat equilibrium equation of internal heat production and heat exchange was derived in accordance with the first and second thermodynamics laws. The temperature of specimens was contributed by the internal heat production and the ambient temperature simultaneously, and a thermo-mechanically coupled thermo-elasto-visco-plastie model was established. The effect of temperature variation of specimens on the mechanical properties of the material was considered in this work. Finally, the capability of the proposed model was validated by comparing the simulated results with the corresponding experimental data of TSMPU.

关键词： Shape memory polyurethane Thermo-mechanical coupling Rate dependence Internal heat production Finite deformation

A systematic study on mycochemical profiles, antioxidant, and anti-inflammatory activities of 30 varieties of Jew’s ear(Auricularia auricula-judae)

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Food Science and Human Wellness 2022年第4期11卷 781-794页

作者： Tahidul Islam Fangjie yao wenyi kang Lixin Lu Baojun Xu College of Horticulture Jilin Agricultural UniversityChangchun 130118China Food Science and Technology Program BNU-HKBU United International CollegeZhuhai 519087China National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China

The health-promoting properties and chemical profiles of 30 Jew’s ear mushroom varieties were investigated. The antioxidant properties were determined by ferric reducing antioxidant power(FRAP), 1,1-diphenyl-2-picrylhydrazyl(DPPH) free radical scavenging, 2,2’-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) free radical scavenging, and metal chelating ability(MCA) assays, while phenolic profiles were determined by total phenol content(TPC) and total flavonoid content(TFC) colorimetric assays. Total carbohydrate, β-glucan, and melanin contents were determined by colorimetric methods. 5’-Nucleotides, vitamin D_(2), ergosterol, and ergothioneine contents were determined by high performance liquid chromatography(HPLC). Anti-inflammation activities of Jew’s ear were evaluated by the colorimetric protease inhibitory method. The results showed that Jew’s ear mushrooms possessed substantial phenolics and antioxidant properties. All the Jew’s ear varieties contain high amount of total carbohydrate, β-glucan, reducing sugar, melanin, pectin, vitamin D2, ergosterol, and ergothioneine. The current findings could provide scientific information for breeders to nurture desired varieties and for food industry to develop new health promoting products.

关键词： Auricularia auricula-judae Phenolic compounds Antioxidant properties Chemical composition Anti-inflammation High performance liquid chromatography

An overview on the major mycotoxins in food products:characteristics,toxicity,and analysis

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Journal of Future Foods 2022年第2期2卷 91-102页

作者： Raghda A.El-Sayed ali B.Jebur wenyi kang Fatma M.El-Demerdash Department of Environmental Studies Institute of Graduate Studies and ResearchAlexandria UniversityAlexandria 21526Egypt Department of Animal Production College of AgricultureUniversity of KerbalaKerbala 56001Iraq National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China

Mycotoxins are potentially hazardous secondary metabolites produced by filamentous fungi(molds).These small molecular weight compounds(often less than 1000 Da)are found in nature and are almost *** can infiltrate our food chain either directly or indirectly through contaminated plant-based food components or toxigenic fungal development on *** can build up in ripening corn,cereals,soybeans,sorghum,peanuts,and other food and feed crops in the field and during *** and animals can get sick from eating mycotoxin-contaminated food or feed,which can result in acute or chronic *** addition to worries regarding direct consumption of mycotoxin-contaminated foods and feeds,the public is concerned about the possibility of ingesting mycotoxin residues or metabolites in animal-derived food products such as meat,milk,or *** fungal genera dominate mycotoxin production:Aspergillus,Fusarium,and *** more than 300 mycotoxins have been found,only six of them(aflatoxins,trichothecenes,zearalenone,fumonisins,ochratoxins,and patulin)are consistently detected in food,posing unpredictability and continuous food safety issues *** article focused on some of them,which are typically found in foods that have been contaminated by one or more of these mycotoxins.

关键词： Fungi Mycotoxins Occurrence Analysis Toxicity

Comparative analysis of antioxidant activities of essential oils and extracts of fennel(Foeniculum vulgare Mill.)seeds from Egypt and China

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Food Science and Human Wellness 2019年第1期8卷 67-72页

作者： Adel F.Ahmed Mengjin Shi Cunyu Liu wenyi kang Medicinal and Aromatic Plants Researches Department Horticulture Research InstituteAgricultural Research CenterEgypt Joint International Research Laboratory of Food&Medicine Resource Function Henan ProvinceKaifeng 475004China National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China

The present study was conducted to assay the antioxidant activities of essential oils and ethanol extracts of fennel(Foeniculum vulgare Mill.)seeds from Egypt and *** major components of the Egyptian fennel essential oil were estragole(51.04%),limonene(11.45%),l-fenchone(8.19%)and trans-anethole(3.62%)by GC–MS ***,the major constituents of Chinese fennel essential oil were transanethole(54.26%),estragole(20.25%),l-fenchone(7.36%)and limonene(2.41%).The fennel seed extracts from Egypt and China contained appreciable levels of total phenolic contents(42.24 and 30.94 mg PE/g,respectively).The extracts exhibited good DPPH radical scavenging capacity with IC50(6.34 and 7.17 mg/g),respectively.A high variation in free radical scavenging activities of essential oils was *** Chinese fennel essential oil showed high activity in DPPH radical scavenging with IC50(15.66 mg/g).The Egyptian fennel essential oil showed very low activity with IC50(141.82 mg/g).The results of the present investigation demonstrated significant variations in the antioxidant activities of fennel essential oils and extracts from Egypt and China.

关键词： Foeniculum vulgare Essential oils GC-MS Total phenolic contents Antioxidant activities

Application and prospects of proteomic technology in inflammation:a review

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Food Science and Human Wellness 2024年第5期13卷 2373-2385页

作者： Senye Wang yanhai Chu Jiajia yuan yiqi Li Zhenhua Liu Xiaoyu Chen wenyi kang National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Functional Food Engineering Technology Research Center Kaifeng 475004China Joint International Research Laboratory of Food&Medicine Resource Function Kaifeng 475004China College of Agriculture Henan UniversityKaifeng 475004China

Proteomics is a new technology that has been widely applied in the field of life and health *** effectively addresses issues related to the impact of dietary structure on organs,tissues,and cells,as well as the changes in proteins in various organs,tissues,and cells under disease *** differential proteins identified through proteomics can serve as disease biomarkers and target proteins affecting health and can be used for disease diagnosis and health *** this paper,the application of proteomics in the field of infl ammation in recent years was summarized,especially in the therapeutic target and mechanism of action,which opens up a new way for more effective prevention,diagnosis,and treatment of inflammation,and provides medical protection for human life and health.

关键词： Proteomics technology Inflammation Biomarkers Potential target Signaling pathway