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World Journal of Clinical Cases 2024年第5期12卷 1033-1035页

作者： Fernando cardona Unitat de Genètica Molecular Instituto de Biomedicina de Valencia–CSICValencia 46010Spain Centro de investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud Carlos IIIMadrid 28029Spain Departamento de Biotecnología Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural(ETSIAMN)Univeristat Politècnica de ValenciaValencia 46022Spain

This letter praises a recent article in the World Journal of Clinical Cases(Roles of biochemistry data,lifestyle,and inflammation in identifying abnormal renal function in old Chinese),examining factors affecting abnormal renal function in elderly Chinese using advanced machine *** highlights the importance of uric acid,age,hemoglobin,body mass index,sport hours,and systolic blood *** study's holistic approach,integrating lifestyle and inflammation,offers a nuanced understanding of chronic kidney disease risk *** letter suggests exploring mechanistic pathways of hyperuricemia,the link between anemia and renal function,and the connection between body mass index and estimated glomerular filtration *** advocates investigating physical activity's impact on renal health and the independent effects of blood *** study significantly contributes to chronic kidney disease understanding,proposing avenues for further exploration and *** are extended to the authors and the journal.

关键词： Biochemistry data Lifestyle Machine learning Renal function

Adverse events in critical care: Search and active detection through the Trigger Tool

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World Journal of Critical Care Medicine 2018年第1期7卷 9-15页

作者： Francisco J Molina Paula T Rivera alejandro cardona Diana C Restrepo Oralia Monroy Daniel Rodas Juan G Barrientos Clínica Universitaria Bolivariana School of Medicine Universidad Pontificia Bolivariana Faculty of Nursing Universidad de Caldas School of Medicine Universidad Pontificia Bolivariana Clínica Universitaria Bolivariana

AIM To investigate the incidence of disadvantageous events by using the Global Trigger Tool in an intensive care unit(ICU).METHODS A retrospective descriptive study was performed in a 12-bed university ICU in the city of Medellin, Colombia. Clinical charts of hospitalized patients were reviewed, between January 1 and December 31, 2016, with the following inclusion criteria: subjects aged over 18 years, with at least 24 h of hospitalization and who had a complete medical history that could be accessed. Interventions: Trained reviewers conducted a retros pective examination of medical charts searching for clue events that elicit investigation, in order to detect an unfavorable event. Measurements: Information was processed through SPSS softwareversion 21; for numerical variables, the mean was reported with standard deviation(SD). Percentages were calculated for qualitative variables. RESULTS Two hundred and forty-four triggers occurred, with 82.4% of subjects having presented with at least one and an average of 3.37 (SD 3.47). A total of 178 adverse events (AEs) took place in 48 individuals, with an incidence of 52.1%. On average, four events per patient were recorded, and for each unfortunate event, 1.98 triggers were presented. The most frequent displeasing issues were: pressure ulcers(17.6%), followed by complications or reactions to medical devices(4.3%), and lacerations or skin defects(3.7%); the least frequent was delayed diagnosis or treatment (0.56%). Thirty-eight point four percent of mishap events caused temporary damage that required intervention, and 48.9% of AEs were preventable. Comparison between AEs and admission diagnoses found that hypertension and sepsis were the only diagnoses that had statistical significance (P = 0.042 and 0.022, respectively).CONCLUSION Almost half of the unfavorable issues were classified as avoidable, which leaves a very wide field of work in terms of preventative activities.

关键词： Adverse events Critical care Trigger Tool Complications Security

Rainfall Sensitivity to Microphysics and Planetary Boundary Layer Parameterizations in Convection-Permitting Simulations over Northwestern South America

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Journal of Meteorological Research 2024年第4期38卷 805-825页

作者： K.Santiago HERNANDEZ Sebastian GOMEZ-RIOS Juan J.HENAO Vanessa ROBLEDO Alvaro RAMiREZ-cardona Angela M.RENDON Geolimna Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Grupo de Ingenieria y Gestion Ambiental(GIGA) Escuela AmbientalFacultad de IngenieriaUniversidad de AntioquiaMedellin 050010Colombia Division of Atmospheric Sciences Desert Research InstituteRenoNV 89512USA

Convection-permitting modeling allows us to understand mechanisms that influence rainfall in specific ***,microphysics parameterization(MP) and planetary boundary layer(PBL) schemes remain an important source of uncertainty,affecting rainfall intensity,occurrence,duration,and ***,we study the sensitivity of rainfall to three MP [Weather Research and Forecasting(WRF) Single-Moment 6-class(WSM6),Thompson,and Morrison] and two PBL [the Yonsei University(YSU) and Mellor–Yamada Nakanishi Niino(MYNN)] schemes with a convection-permitting resolution(4 km) over northwestern South America(NWSA).Simulations were performed by using the WRF model and the results were evaluated against soundings,rain gauges,and satellite data,considering the spatio-temporal variability of rainfall over diverse regions prone to deep convection in *** and PBL schemes largely influenced simulated rainfall,with better results for the less computationally expensive WSM6 MP and YSU PBL *** rain gauges and satellite estimates,simulations with Morrison MP overestimated rainfall,especially westward of the Andes,whereas the MYNN PBL underestimated precipitation in the Amazon–Savannas *** found that the uncertainty in the rainfall representation is highly dependent on the region,with a higher influence of MP in the Colombian Pacific and PBL in the Amazon–Savannas *** analyzing rainfall-related processes,the selection of both MP and PBL parameterizations exerted a large influence on the simulated lower tropospheric moisture flux and moisture *** schemes significantly influenced the downward shortwave radiation,with MYNN simulating a greater amount of low clouds,which decreased the radiation ***,latent heat fluxes were greater for YSU,favoring moist convection and *** schemes had a marked impact on vertical ***,Morrison MP showed stronger convection and higher precipitation rates,which is assoc

关键词： sensitivity microphysics planetary boundary layer(PBL) Weather Research and Forecasting(WRF) processes

Optimized Convolutional Neural Network Models for Skin Lesion Classification

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Computers, Materials & Continua 2022年第2期70卷 2131-2148页

作者： Juan Pablo Villa-Pulgarin Anderson Alberto Ruales-Torres Daniel Arias-GarzónMario alejandro Bravo-Ortiz Harold Brayan Arteaga-Arteaga alejandro Mora-RubioJesus alejandro Alzate-Grisales Esteban Mercado-Ruiz M.Hassaballah Simon Orozco-Arias Oscar cardona-Morales Reinel Tabares-Soto Department of Electronics and Automation Universidad Autónoma deManizalesManizales170001Colombia SEDMATEC Corporación Universitaria Autónoma de Nari駉Pasto520002Colombia Department of Computer Science Faculty of Computers and InformationSouth Valley UniversityQena83523Egypt Department of Computer Science Universidad Autónoma de ManizalesManizales170001Colombia Department of Systems and Informatics Universidad de CaldasManizales170001Colombia

Skin cancer is one of themost severe diseases,andmedical imaging is among themain tools for cancer *** images provide information on the evolutionary stage,size,and location of tumor *** paper focuses on the classification of skin lesion images considering a framework of four experiments to analyze the classification performance of Convolutional Neural Networks(CNNs)in distinguishing different skin *** CNNs are based on transfer learning,taking advantage of ImageNet ***,in each experiment,different workflow stages are tested,including data augmentation and fine-tuning *** CNN models based on DenseNet-201,Inception-ResNet-V2,and Inception-V3 are proposed and compared using the HAM10000 *** results obtained by the three models demonstrate accuracies of 98%,97%,and 96%,***,the best model is tested on the ISIC 2019 dataset showing an accuracy of 93%.The proposed methodology using CNN represents a helpful tool to accurately diagnose skin cancer disease.

关键词： Deep learning skin lesion convolutional neural network data augmentation transfer learning

Inverse methodology as applied to reconstruct local textile features from measured pressure field

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Journal of Materials Science & Technology 2021年第12期71卷 241-247页

作者： S.Bancora C.Binetruy S.Advani Comas-cardona Ecole Centrale de Nantes Research Institute in Civil Engineering and Mechanics(GeM)UMR CNRS 618344321 Nantes Cedex 3France Department of Mechanical Engineering University of DelawareNewarkDelaware 19716USA

One can compute the final deformation of a known geometry under specific boundary conditions using the constitutive laws of mechanics that describe their stress strain *** such cases the initial geometry is known,and all operators mapping the deformation are defined on the reference ***,there are situations in which the final configuration of a deformation might be known but not the *** inverse formulation allows one to determine the initial geometry of a domain,given its final deformation state,the material behavior law and a set of boundary *** the present work we propose a method to reconstruct the mesoscale geometry of a textile based on its mechanical response during *** do so,stress boundary conditions are acquired by means of a pressuresensitive *** adopting an appropriate material law,the thickness and width information of the yarns are deduced from the pressure field experienced by the compacted *** 3 D scanning techniques such as-CT,the proposed method can be applied on any domain size,allowing long-range variability to be *** the best of the authors’knowledge,there are no previous works that use a pressure-sensitive film on a large domain to capture the input data for a shape *** example application serves as a demonstration of a methodology which could be applied to other classes of materials.

关键词： Textiles Pressure sensors Inverse method Digital twin Geometry reconstruction Hyperelasticity

Meningoencephalitis due to Listeria monocytogenes in a Young Immunocompetent Patient: Case Report with Literature Review

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Advances in Infectious Diseases 2024年第1期14卷 213-219页

作者： Janette Alejandra Gamiño Gutierrez Gustavo Adolfo Hernández Valdez Arleth Anahí Montaño Gómez Jorge Morales Rojas Graciela Gaddy Robles Martinez Anahi Herrera Ruelas Alin Kaori Ferreyra Gudiño Jocelin Celeste Jurado cardona Jimena Jexabeth Ibáñez Núñez Anahí Fierros Ramos Departmento de Neurocirugia Hospital Civil de Guadalajara Fray Antonio Alcalde Guadalajara México Departamento de Medicina Interna ISSSTE Tepic General Hospital APP Tepic México

Meningoencephalitis secondary to Listeria monocytogenes (L. monocytogenes) mainly affects newborns, the elderly and immunocompromised people;there are extremely rare cases in which said infection occurs in immunocompetent individuals. We present the case of a young adult patient without immunocompromise, who developed meningoencephalitis due to L. monocytogenes;This case is exceptional, since it occurred in an individual outside the classic age group, in addition to not having risk factors, which is why it should be considered an atypical causal agent.

关键词： Meningitis Encephalitis Rhombencephalitis Listeria monocytogenes Immunocompetent

Evaluation of biostimulation and Tween 80 addition for the bioremediation of long-term DDT-contaminated soil

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Journal of Environmental Sciences 2015年第2期27卷 101-109页

作者： Bibiana Betancur-Corredor Nancy J.Pino Santiago cardona Gustavo A.Peuela GDCON Research Group Faculty of Engineering University Research Headquarters (SIU) University of Antioquia School of Geosciences and Environment Faculty of Mines National University of Colombia School of Microbiology University of Antioquia

The bioremediation of a long-term contaminated soil through biostimulation and surfactant addition was evaluated. The concentrations of 1,1,1-trichloro-2,2-bis（4-chlorophenyl）ethane（DDT） and its metabolites 1,1-dichloro-2,2-bis（4-chlorophenyl） ethane（DDD） and1,1-dichloro-2,2-bis（4-chlorophenyl） ethylene（DDE） were monitored during an 8-week remediation process. Physicochemical characterization of the treated soil was performed before and after the bioremediation process. The isolation and identification of predominant microorganisms during the remediation process were also carried out. The efficiency of detoxification was evaluated after each bioremediation protocol. Humidity and p H and the heterotrophic microorganism count were monitored weekly. The DDT concentration was reduced by 79% after 8 weeks via biostimulation with surfactant addition（B ＋ S） and 94.3%via biostimulation alone（B）. Likewise, the concentrations of the metabolites DDE and DDD were reduced to levels below the quantification limits. The microorganisms isolated during bioremediation were identified as Bacillus thuringiensis, Flavobacterium sp., Cuprivadius sp.,Variovorax soli, Phenylobacterium sp. and Lysobacter sp., among others. Analysis with scanning electron microscopy（SEM） allowed visualization of the colonization patterns of soil particles. The toxicity of the soil before and after bioremediation was evaluated using Vibrio fischeri as a bioluminescent sensor. A decrease in the toxic potential of the soil was verified by the increase of the concentration/effect relationship EC50 to 26.9% and 27.2% for B ＋ S and B, respectively, compared to 0.4% obtained for the soil before treatment and 2.5%by natural attenuation after 8 weeks of treatment.

关键词： DDT Soil Bioremediation Biostimulation Surfactant Toxicity

Features of the motion of gel particles in a three-phase bubble column under foaming and non-foaming conditions

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Chinese Journal of Chemical Engineering 2018年第6期26卷 1370-1382页

作者： Gabriel Salierno Mauricio Maestri Stella Piovano Miryan Cassanello Maria Angelica cardona Daniel Hojman Hector Somacal Laboratorio de Reactores y Sistemas para la lndustria-LARSl Dep. lndustrias FCEyN Universidad de Buenos Aires Int. GiJiraldes 2620 CI428BGA Buenos Aires Argentina Laboratorio de Diagnóstico por Radiaciones-LADiR Dep. de Fisica Experimental. Comision National de Energia Atomica (CNEA) San Martin Buenos Aires Argentina Universidad de San Martin San Martin Buenos Aires Argentina

Features of the motion of gel particles in a three-phase bubble column with non-foaming and foaming gas–liquid systems,determined by using experiments of radioactive particle tracking(RPT),have been *** tracer used is a gel particle which resembles typical immobilized *** tracer trajectory is analyzed to extract relevant information for design *** solid velocity field,turbulence parameters,dispersion coefficients,mixing times and flow transitions are determined and *** presence of foam significantly affects many quantified parameters,especially within the heterogeneous flow *** hydrodynamic stresses are reduced in the presence of foam,especially close to the *** dispersion coefficients also decrease,and the solid mixing time is only slightly affected by the presence of *** holdup,inferred both from RPT experiments and from gamma ray scanning,is higher for foaming systems and leads to a shift in the transition gas velocity towards higher values.

关键词： Bubble columns Solid motion Gel beads Foaming Particle tracking Mixing

Central nervous system stimulation therapies in phantom limb pain:a systematic review of clinical trials

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Neural Regeneration Research 2022年第1期17卷 59-64页

作者： M.Ángeles García-Pallero Diana cardona Lola Rueda-Ruzafa Miguel Rodriguez-Arrastia Pablo Roman Hospital Universitario Central de Asturias AsturiasSpain Department of Nursing Science Physiotherapy and MedicineUniversity of AlmeríaAlmeríaSpain Department of Functional Biology and Health Sciences Faculty of Biology-CINBIOUniversity of VigoVigoPontevedraSpain Faculty of Health Sciences Pre-Department of NursingJaume I UniversityCastello de la PlanaSpain Research Group CYS Faculty of Health SciencesJaume I UniversityCastello de la PlanaSpain

Phantom limb pain is a chronic pain syndrome that is difficult to cope *** neurostimulation treatment is indicated for refractory neuropathic pain,there is scant evidence from randomized controlled trials to recommend it as the treatment ***,a systematic review was performed to analyze the efficacy of central nervous system stimulation therapies as a strategy for pain management in patients with phantom limb pain.A literature search for studies conducted between 1970 and September 2020 was carried out using the MEDLINE and Embase *** of The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline were *** were a total of 10 full-text articles retrieved and included in this *** brain stimulation,repetitive transcranial magnetic stimulation,transcranial direct current stimulation,and motor cortex stimulation were the treatment strategies used in the selected clinical *** transcranial magnetic stimulation and transcranial direct current stimulation were effective therapies to reduce pain perception,as well as to relieve anxiety and depression symptoms in phantom limb pain ***,invasive approaches were considered the last treatment option as evidence in deep brain stimulation and motor cortex stimulation suggests that the value of phantom limb pain treatment remains ***,the findings on use of these treatment strategies in other forms of neuropathic pain suggest that these invasive approaches could be a potential option for phantom limb pain patients.

关键词： central nervous system stimulation neuromodulation neuropathic pain phantom limb pain systematic review

The relationship between sexually transmitted microorganisms and seminal quality in asymptomatic men

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Asian Journal of Urology 2022年第4期9卷 473-479页

作者： Valentina Velasquez Rivera Walter D.cardona Maya Jenniffer Puerta-Suarez Department of Microbiology and Parasitology Medical SchoolUniversity of AntioquiaAntioquiaColombia

Objective:To detect DNA of different microorganisms,in semen samples from apparently healthy men and correlate their presence with seminal ***:Semensamples from 81 healthy volunteers were collected,and semen parameters were *** extraction was performed using the phenol-chloroform technique,and the micro-organisms were detected by the amplification of specific primers using polymerase chain ***:DNA from at least one of the microorganisms was detected in 78 *** most frequent microorganism found in semen were:Lactobacillus spp.(70%),Neisseria gonorrhoeae(***)(36%),Streptococcus epidermidis(64%),Klebsiella pneumoniae(56%),Staphylococcus aureus(32%),Chlamydia trachomatis(***)(28%),Pseudomonas aeru-ginosa(27%).The seminal parameters of all semen samples were over the lower reference values fornormal *** compare with negative samples,seminal volume was higher for the Escherichia coli positive samples and lower for Pseudomonas aeruginosa positive *** samples positive for Staphylococcus aureus had worse sperm *** frequency of progressive motility was higher in positive samples for *** and *** semen samples for *** had a higher concentration per ***:It is common to find microorganisms in semen of asymptomatic men,including those responsible for sexually transmitted *** treatment is recommended only in those individuals with a sexually transmitted infection(*** and ***)and always promote condom use.

关键词： Chlamydia trachomatis Neisseria gonorrhoeae Enterococcus faecalis Streptococcus agalactiae Staphylococcus spp. Seminal quality