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Acta Geologica Sinica(english edition) 2015年第6期89卷 1895-1913页

作者： ahmed e.el-RAYeS Mohamed O.ARNOUS Suez Canal University Faculty of SciencesGeology Department

Groundwater in contact with ore deposits may acquire a chemical composition that could be used as a guide for exploration. eight well-water samples are collected from a known uraniummineralized area near Abu Zenima, west central Sinai to examine the applicability of using the hydrogeochemical technique in the search for uranium mineralization in similar arid areas. The analytical chemical data of the ground water is compared with ground radiometric measurements. The obtained results indicate that groundwater affected by uranium mineralization has a specific relativity of major anions expressed essentially as SO_4〉Cl〉HCO_3 and to a lesser extent as Cl〉SO_4〉HCO_3, associated as a rule with low magnesium content. This association constitutes a signature of uranium mineralization on the composition of groundwater in west central Sinai and could be used as an important exploration guide in the search for uranium deposits in similar areas. Anomalies in Ni, Fe, Zn and Cr and other pathfinder elements in groundwater can furnish geochemical guides to uranium ores. The immobile trace.element anomalies, including Zn, Ni and Fe are strongly distributed near the orebody; whereas the relatively mobile trace.elements, including Co, U, V and Cr, constitute the dispersion haloes away from the orebody. A new hydrogeochemical discrimination diagram is constructed to be used as a quick and cost effective exploration tool in the search for uranium occurrences in environmentally similar arid areas. Based on the obtained results, a new site for uranium occurrence, west of W. Baba, is delineated and recommended for future detailed geological and geochemical surveying.

关键词： Hydrogeochemical exploration Uranium ores geospatial mapping graphical explorationtool remote sensing Sinai

GIS-based flash flooding susceptibility analysis and water management in arid mountain ranges:Safaga Region,Red Sea Mountains,egypt

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Journal of Mountain Science 2023年第12期20卷 3665-3686页

作者： ahmed e.el-RAYeS Mohamed O.ARNOUS ahmed M.HelMY Geology Department Faculty of ScienceSuez Canal UniversityIsmailia 41522Egypt Geology Department Faculty of ScienceArish UniversityArish 45511 North SinaiEgypt

The Safaga Region(SR)is part of the Red Sea mountain range in *** flash flooding is now an inescapable event,wreaking havoc and causing massive loss of life and *** majority of the floodwater,however,has been wasted as runoff to the Red Sea,which,if used wisely,could meet a fraction of the water demands for a variety of applications in this *** current work aims to use GIS techniques to integrate remote sensing data for evaluating,mitigating,and managing flash floods in *** data set comprised Tropical Rainfall Measuring Mission(TRMM)thematic rainfall data,1:50,000 scale topographical map sheets,geological maps,the ASTeR Digital elevation Model(ASTeR GDeM),Landsat 7 enhanced Thematic Mapper"(eTM7+),and Landsat 8 Operational Land *** flash flood risk model of SR is de.eloped using ArcGIS-10.3 geoprocessing tools integrating all the causal factors thematic *** final flood risk model for the SR suggests that 57%of the total basins in the SR are at high risk of *** 38%of all basins are at moderate flood *** remaining 5%of basins are less prone to ***-prone zones were identified,suitable dam-building sites were located,and extre.ely probable areas for water recharge were *** the basis of reliable scientific data,structural and non-structural mitigation strategies that might reduce the damage susceptibility,alleviate the sensitivity of the flash flood,and best utilize its water supply were recommended.

关键词： Flash floods GIS Susceptibility Water management Arid mountains egypt

Problems of drinking water treatment along Ismailia Canal Province, egypt

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第3期9卷 232-242页

作者： Mohamed H.GeRIeSH Klaus-Dieter BALKe ahmed e.el-RAYeS Geology Department Faculty of ScienceSuez Canal UniversityP.C.41522IsmailiaEgypt Institute of Geosciences Teubingen University72076 TeubingenGermany

The present drinking water purification system in egypt uses surface water as a raw water supply without a preliminary filtration *** the other hand,chlorine gas is added as a disinfectant agent in two steps,pre-and *** to these reasons most of water treatment plants suffer low filtering effectiveness and produce the trihalomethane(THM) species as a chlorination *** Ismailia Canal represents the most distal downstream of the main Nile *** its water contains all the proceeded pollutants discharged into the *** addition,the downstream reaches of the canal act as an agricultural drain during the closing period of the High Dam gates in January and February every ***,the wide industrial zone along the upstream course of the canal enriches the canal water with high concentrations of heavy *** obtained results indicate that the canal gains up to 24.06×106 m3 of water from the surrounding shallow aquifer during the closing period of the High Dam gates,while during the rest of the year,the canal acts as an influent stream losing about 99.6×106 m3 of its water *** reduction of total organic carbon(TOC) and suspended particulate matters(SPMs) should be one of the central goals of any treatment plan to avoid the disinfectants *** combination of sedimentation basins,gravel pre-filtration and slow sand filtration,and underground passage with microbiological oxidation-reduction and adsorption criteria showed good removal of parasites and bacteria and complete.elimination of TOC,SPM and heavy ***,it reduces the use of disinfectants chemicals and lowers the treatment ***,this purification system under the arid climate prevailing in egypt should be tested and modified prior to application.

关键词： Drinking water treatment Hazardous by-products Natural attenuation Ismailia Canal egypt

Molecular and serological prevalence of Toxoplasma gondii in pregnant women and sheep in egypt

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Asian Pacific Journal of Tropical Medicine 2017年第10期10卷 996-1001页

作者： Hany M.Ibrahim Azza H.Mohamed ahmed A.el-Sharaawy Hend e.el-Shqanqery Department of Zoology Faculty of ScienceMenoufia UniversityShebin El-KomEgypt Clinical Pathology Unit National Liver InstituteMenoufia UniversityEgypt

Objective: To investigate molecular and serological prevalence of Toxoplasma gondii(***) in pregnant women and sheep in ***: Blood samples collected from healthy 364 pregnant women and 170 sheep were investigated for *** antibodies and parasitemia using highly specific and sensitive surface antigen(TgSAG2) based enzyme linked immunosorbent assay(elISA)and real time-polymerase chain reaction(RT-PCR).Results: Overall prevalence of *** was 51.76%, 17.65% in sheep, 33.79%, 11.81%in pregnant women, using elISA and RT-PCR *** differences in *** prevalence were observed on the basis of contact with cats or soil in pregnant women using either RT-PCR or *** pregnant women, a significant increase was detected in aged and those eating under-cooked mutton using simultaneous elISA/***: Consumption of under-cooked infected mutton is an important source of human infection and the combination of the two assays provide accurate and precise data during infection.

关键词： Toxoplasmosis RT-PCR elISA Pregnant-women Sheep

Impact of topical nonsteroidal anti-inflammatory drugs in prevention of macular edema following cataract surgery in diabetic patients

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International Journal of Ophthalmology(english edition) 2018年第4期11卷 616-622页

作者： ahmed A.Alnagdy Hossam Y.Abouelkheir Sherief e.el-Khouly Sahar M.Tarshouby Mansoura Ophthalmic Center Faculty of Medicine Mansoura University

AIM： To evaluate the efficacy of prophylactic administration of topical non-steroidal anti-inflammatory drugs（NSAIDs） on macular edema following cataract surgery in diabetic patients, and to compare between types of NSAIDs（ketorolac tromethamine 0.4% and nepafenac 0.1%）. MeTHODS： Group 1（control） received artificial tears substitute as a placebo group, group 2（nepafenac） received topical nepafenac 0.1%, and group 3（ketorolac） received topical ketorolac tromethamine 0.4%. Patients were examined postoperatively after completing one week, one month, two months and three months＇ intervals for evaluating cystoid macular edema（CMe） de.elopment. The main study outcomes were achieving the best corrected visual acuity（BCVA） and change in the central macular thickness（CMT） measured with optical coherence topography（OCT）.ReSULTS： eighty eyes of 76 patients were included in this study. BCVA showed a statistically significant difference at the third month postoperative follow up between the control group and the NSAIDs groups（P=0.04）. There was an increase in the CMT in all cases starting from postoperative first week until third month. CMT showed a statistically significant difference between control group and NSAIDs groups from postoperative first month until third month（P=0.008, 0.027, 0.004）. There was no statistically significant difference between nepafenac and ketorolac groups in BCVA and OCT CMT. CONCLUSION： Prophylactic preoperative and postoperative NSAIDs may have a role in reducing the frequency and severity of CMe in diabetic eyes following cataract surgery.

关键词： diabetes mellitus cataract surgery central macular thickness non-steroidal anti-inflammatory drugs ketorolac nepafenac

Carnosine and crocin ameliorate oxidative stress in rats with rhabdomyolysis-induced acute kidney injury through upregulating HO-1 gene expression

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Food Bioscience 2022年第5期49卷 904-914页

作者： Nahla e.el-Ashmawy eman G.Khedr ahmed S.Doghish Mohammed S.elballal Department of Biochemistry Faculty of PharmacyTanta UniversityTantaEgypt Department of Biochemistry Faculty of PharmacyBadr University in Cairo(BUC)Badr CityCairo11829Egypt Department of Biochemistry and Molecular Biology Faculty of Pharmacy(Boys)Al-Azhar UniversityNasr CityCairo11651Egypt

We aimed to investigate whether carnosine(a natural dipeptide found in humans)and crocin(a natural product extracted from saffron and gardenia)can prevent the harmful effects of acute kidney injury(AKI)caused by glycerol-induced rhabdomyolysis with a focus on the role of the nuclear factor e2-related factor-2/heme oxygenase-1(Nrf2/HO-1)signaling ***-six male Wistar rats were divided into 6 groups:3 of them received saline,carnosine,and crocin IP for 7 days and the other 3 groups received the same treatment in addition to a single IM injection of 50%glycerol(10 ml/kg,divided between the two limb muscles)on 8th *** animals were sacrificed after 24 h of the IM *** samples,muscles,and kidneys were collected for further *** was evidenced by the histopathological alterations in muscle sections and increased le.els of myoglobin in kidney tissue homogenate *** injury was characterized by increased creatinine,kidney injury molecule-1,malondialdehyde,nitric oxide,and decreased catalase *** injury also increased inflammatory markers and histopathological alterations in kidney *** these effects were corrected by pretreatment with carnosine and *** agents could also elevate HO-1 gene ***,both agents failed to restore the declined Nrf2 expression in glycerol-treated *** and crocin can effectively prevent rhabdomyolysis-induced AKI in rats through augmenting gene expression of HO-1 and antioxidant system and suppressing the generation of reactive oxygen species,lipid peroxidation,and inflammatory response.

关键词： Carnosine Crocin Acute kidney injury Rhabdomyolysis Antioxidant

Selective micellar electrokinetic chromatographic method for simultaneous determination of some pharmaceutical binary mixtures containing non-steroidal anti-inflammatory drugs

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Journal of Pharmaceutical Analysis 2013年第1期3卷 53-60页

作者： Michael e.el-Kommos Niveen A.Mohamed ahmed F.Abdel Hakiem Department of Pharmaceutical Analytical Chemistry Faculty of PharmacyAssiut University

A simple and selective micellar electrokinetic chromatographic （MeKC） method has been de.eloped for the analysis of five pharmaceutical binary mixtures containing three non-steroidal antiinflammatory drugs （NSAIDs）. The investigated mixtures were Ibuprofen （IP）-Paracetamol （PC）, Ibuprofen （IP）-Chlorzoxazone （CZ）, Ibuprofen （IP）Methocarbamol （MC）, Ketoprofen （KP） Chlorzoxazone （CZ） and Diclofenac sodium （DS）-Lidocaine hydrochloride （LC）. The separation was run for all mixtures using borate buffer （20 mM, pH 9） containing 15% （v/v） methanol and 100 mM sodium dodecyl sulphate （SDS） at 15 kV and the components were detected at 214 nm. Different factors affecting the.electrophoretic mobility of the seven investigated drugs were studied and optimized. The method was validated according to international conference of harmonization （ICH） guidelines and United States pharmacopoeia （USP）. The method was applied to the analysis of five pharmaceutical binary mixtures in their dosage forms. The results were compared with other reported high performance liquid chromatographic methods and no significant differences were observed.

关键词： Capillaryelectrophoresis Micellar electrokineticchromatographicmethod Non-steroidalanti-inflammatorydrugs Pharmaceutical binarymixtures Pharmaceutical analysis

Molecular detection of virulence genes in Campylobacter species isolated from livestock production systems in South Africa

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Journal of Integrative Agriculture 2020年第6期19卷 1656-1670页

作者： Bongekile NGOBeSe Oliver Tendayi ZISHIRI Mohamed ezzat el zowalaty Discipline of Genetics School of Life SciencesUniversity of KwaZulu-NatalDurban 4000South Africa Zoonosis Science Center Department of Medical Biochemistry and MicrobiologyUppsala UniversityUppsala SE-75185Sweden Infectious Diseases and Anti-Infective Therapy Research Group College of Pharmacy and Sharjah Medical Research InstituteUniversity of SharjahSharjah 27272UAE

Campylobacter species are a major cause of foodborne bacterial infections in both de.eloped and de.eloping countries *** jejuni is responsible for the majority of infectio *** study was con ducted to identify virule nceassociated genes in Campylobacter species isolated from livestock production systems in South Africa.A total of 250 fecal samples consisting of cattle(n=50),chickens(n=50),goats(n=50),sheep(n=50)and pigs(n=50)were randomly collected from livestock in eastern Cape and KwaZulu-Natal provinces of South Africa between April and October *** samples were an a lyzed for the presence of virule nee genes in Campylobacter species using molecular PCR-based *** was found that 77 and 23%of Campylobacter jejuni and Campylobacter coli respectively were isolated from all the livestock *** were positive significant(Pelations amongst all the virulenee genes that were *** and Fisher's exact tests were implemented to test for the effect of livestock species on the presenee or absenee of virule nee gen *** study dem on strated that most of livestock species can pote ntially cause zoonotic infecti on s and food pois oning due to the high prevale nee of *** high prevale nee of virule nee genes highlights the sign ifica nee of Campylobacter\r\livestock production systems in South *** requires the implementation of one-health approaches to reduce the impact of foodborne and zoonotic diseases for the welfare of human and animal health.

关键词： Campylobacter zoonotic cytotoxicity pathogenicity virulenee campylobacteriosis foodbome livestock PCR one-health

effects of extender and packaging method on morphological and functional characteristics of cryopreserved Ossimi ram semen

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Asian pacific Journal of Reproduction 2020年第3期9卷 148-155页

作者： Wael A.Khalil Abdel-Khalek e.Abdel-Khalek Laura Falchi Bedir e.el-Saidy ahmed I.Yousif Department of Animal Production Faculty of AgricultureMansoura UniversityMansoura35516Egypt Department of Veterinary Medicine Section of Obstetrics and GynecologyUniversity of SassariSassari07100Italy Animal Production Research Institute Agriculture Research CentreMinistry of AgricultureEgypt

Objective:To test the effects of extenders and packaging methods on morphological and functional characteristics of frozen thawed Ossimi ram ***:Ram semen was pooled,diluted in 3 different extenders:Tris-egg yolk(TeY),Tris-soybean lecithin(TSBL),and Tris-butylatedhydroxytoluene(TBHT),equilibrated at 5℃for 4 h,and packaged in straws or pellets for *** was evaluated for sperm progressive motility,viability,abnormality,and membrane integrity after dilution,equilibration and *** percentages of viable,early apoptotic,apoptotic,and necrotic spermatozoa as well as comet assay parameters were determined in post-thawed *** antioxidants capacity,malondialdehyde and lactic dehydrogenase were assayed in thawed seminal ***:After equilibration,only sperm membrane integrity was significantly higher(PeY and TSBL than in *** thawing,TeY or TSBL in straws significantly improved sperm progressive motility and vitality(Ped seminal plasma,TBHT or TSBL in straws and TBHT in pellets significantly reduced malondialdehyde,and TBHT in pellets significantly increased lactic dehydrogenase(PeY in straws increased viable sperm,while significantly decreased early apoptotic and apoptotic sperm(Pe was significantly decreased(PeY and TSBL,and tail moment decreased in straws with all extenders(Pespite the disadvantages of dilution of cryopreserved semen with egg yolk,ram semen cryopreserved with TeY gives the best physical,morphological and functional characteristics in straws compared with pellets,followed by semen diluted with ***,semen diluted with TBHT or TSBL,regardless of packaging method,showed the highest impact on antioxidant status of cyopreserved ram semen.

关键词： Cryopreservation egg-yolk Lecithin Sperm Ossimi ram