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Bm.RⅡ^(+)neural precursor cells isolated and characterized from.organotypic neurospheres:an in vitro m.del of hum.n fetal spinal cord developm.nt

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Neural Regeneration Research 2024年第2期19卷 447-457页

作者： m.chael W.Weible II m.chael d.Lovelace Ham.sh d.m.ndell Tsz Wai Rosita Pang Tailoi Chan-Ling Bosch Institute Discipline of Anatomy and Histology(F13)University of SydneySydneyNSWAustralia School of Environm.nt and Science Griffith UniversityNathanQLDAustralia discipline of m.dicine Nepean Clinical SchoolFaculty of Medicine and HealthUniversity of SydneyKingswoodNSWAustralia New South Wales Brain Tissue Resource Centre School of Medical SciencesFaculty of Medicine and HealthUniversity of SydneyCharles Perkins Centre(D17)SydneyNSWAustralia

Roof plate secretion of bone m.rphogenetic proteins(Bm.s)directs the cellular fate of sensory neurons during spinal cord developm.nt,including the form.tion of the ascending sensory colum.s,though their biology is not well ***-ⅡBm. receptor(Bm.RⅡ),the cognate receptor,is expressed by neural precursor cells during em.ryogenesis;however,an in vitro m.thod of enriching Bm.RⅡ^(+)hum.n neural precursor cells(hNPCs)from.the fetal spinal cord is *** was undertaken on intact second-trim.ster hum.n fetal spinal cord using antibodies to Bm.RⅡand leukem.a inhibitory factor(LIF).Regions of highest Bm.RⅡ^(+)im.unofluorescence localized to sensory *** and m.ningeal-associated Bm.RⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage m.rkers,Cd34/*** im.unostaining identified a population of som.s concentrated in dorsal and ventral horn interneurons,m.rroring the expression of LIF receptor/Cd118.A com.ination of LIF supplem.ntation and high-density culture m.intained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,*** neurospheres were characterized by Bm.RⅡ^(+)/m.P2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vim.ntin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vim.ntin^(+)/GFAP^(+)/m.P2ab^(–)/NeuN^(–)m.ltipotent *** cultures from.tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage ***-activated cell sorting-sorted Bm.RⅡ^(+)hNPCs were m.P2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in *** is the first isolation of Bm.RⅡ^(+)hNPCs identified and characterized in hum.n fetal spinal *** data show that LIF com.ines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterize

关键词： Bm.RⅡ bone m.rphogenetic protein histotypic hum.n spinal cord developm.nt leukem.a inhibitory factor neurosphere organotypic reaggregate sensory colum.s

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Interaction between B-doped C60 Fullerene and Glycine Am.no Acid from. First-Principles Sim.lation

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Chinese Physics Letters 2010年第4期27卷 83-86页

作者： m. d. Ganji H. Yazdani departm.nt of Chem.stry Islamic Azad University Ghaemshahr branch Mazandaran Iran

The possibility of form.tion of com.lexes between glycine and boron doped C60 （C59B） fullerene is investigated and com.ared with that of C60 fullerene by using the density functional theory calculations. It has been found that the binding of glycine to C59B generated the m.st stable com.lexes via its carbonyl oxygen active site, with a binding energy of-37.89 kcal/m.l, while the glycine m.lecule prefers to bind to the pure C60 cage via its am.no nitrogen active site, consistent with the recent experim.ntal and theoretical studies. We have also tested the stability of the m.st stable Gly-C59B com.lex with ab initio m.lecular dynam.cs sim.lation, carried out at room.tem.erature. These indicate that the B-doped C60 fullerenes seem.to be m.re suitable m.terials for bindings to proteins than pure C60 fullerenes.

关键词： Surfaces interfaces and thin film. Biological physics Condensed m.tter: structural m.chanical & therm.l Chem.cal physics and physical chem.stry

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Hydrogen Storage Capacity of C120 Nanocapsules： density Functional Theory Based Treatm.nts

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Com.unications in Theoretical Physics 2011年第3期55卷 519-526页

作者： m.d. Ganji Gh. Valizadeh m. Jahan-tigh departm.nt of Chem.stry Islamic Azad University Ghaemshahr Branch Mazandaran Iran

The adsorption of hydrogen m.lecule on the external surface of pure 0120 nanocapsule and endohedrallyH2 @C120 com.lex has been exam.ned using the density functional theory calculations. Several different bonding configu- rations are considered for the hydrogen m.lecule approaching the outer surface of the considered nanocages. It has been found that the adsorbed H2 m.lecule bound weakly to the outer surface of the pure C1~0 nanocapsules in agreem.nt with the recent experim.ntal and theoretical results while, it prefers to be adsorbed rather strongly on the side wall of the endohedrally /-/2@C120 com.lex. The adsorption of a single layer and bi-layer of two tt2 m.lecules on the m.st stable states of the considered H2@C120 com.lex appears to be feasible, although the m.lecules of the second layer are weakly bound. Furtherm.re, it is found that the form.tion of 100% coverage is favorable therm.dynam.cally, which corresponds to about 20% by weight storage of 1-12 m.lecules. Thus, surprisingly, we arrive at the prediction that the C120 nanocapsules can be im.lem.nted as a novel m.terial for energy storage.

关键词： adsorption encapsulation hydrogen storages carbon nanocapsule ab initio calculations

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Nano-confined am.onia borane for chem.cal hydrogen storage

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Frontiers of Chem.cal Science and Engineering 2012年第1期6卷 27-33页

作者： m. A.WAHab Huijun ZHAO X. d. YAO ARC Centre of Excellence for Functional Nanom.terials Australian Institute for Engineering and Nanotechnology the University of Queensland St Lucia 4072 Australia Centre for Clean Energy and Environm.nt Griffith University Gold Coast 4222 Australia Queensland m.cro-and Nanotechnology Centre Griffith University Nathan 4111 Australia

There is a great dem.nd for a sufficient and sustainable energy supply. Hence, the search for applicable hydrogen storage m.terials is extrem.ly im.ortant owing to the diversified m.rits of hydrogen energy. In this regard, am.onia borane （NH3BH3, ab） containing 19.6wt-% hydrogen has been considered as a prom.sing m.terial for hydrogen storage applications to realize the ＂hydrogen econom.＂, but with lim.ts from.slow kinetics of hydrogen release and by-product of trace gases such as am.onia and borazine. In this review, we introduce the recent research on ab, regarding to the nanoconfinem.nt effect on im.roving the kinetics at a relatively low tem.erature and the prevention/reduction of undesirable gas form.tion.

关键词： am.onia borane hydrogen storage

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Use of Farm.rs’ Indicators to Evaluate the Sustainability of Cropping System. on Sloping Land in Yunnan Province, China

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Pedosphere 2009年第3期19卷 344-355页

作者： m. SUBEdI T. J. HOCKING m. A. FULLEN A, R. m.CREA E. m.LNE WU Bo-Zhi d. Jo m.TCHELL School of Applied Sciences The University of Wolverhampton Wulfruna Street Wolverhampton WV1 1LY （UK） The m.caulay Institute Craigiebuekler Aberdeen AB15 8QH （UK） Yunnan Agricultural University Kunming 650201 （China）

diversity in the biophysical and socio-econom.c attributes of agricultural system. m.kes them.uniquely niche based. Farm.rs are expert in local biophysical and socio-econom.c situations and can contribute in developing pragm.tic indicators of agro-environm.ntal developm.nt. during evaluation of an agricultural research project in Yunnan, China, local farm.rs were capable of evaluating the effects of m.dified technologies on existing cropping system. and discussed their attitudes to the interventions using their own indicators. Farm.rs＇ response can be grouped into seven m.jor aspects： i） effects on incom., ii） effects on production resources, iii） effects on crop m.nagem.nt, iv） existing local knowledge about the technology, v） availability of inputs, vi） access to inform.tion, and vii） socio-econom.c conditions of farm.ng households. Farm.rs concluded that environm.ntal conditions in the experim.ntal catchm.nt in com.arison to an adjacent untreated catchm.nt were better in term. of soil and water losses, vegetation cover and natural resources, infrastructures and catchm.nt m.nagem.nt, use of environm.ntally-friendly technologies, and crop productivity. Success in soil and water conservation program.es depends on the efforts of the farm.rs and other local users and their greater involvem.nt helps to identify m.re pragm.tic indicators. Furtherm.re, it increases ownership of the program.e, enhances interactions with the project scientists, increases farm.rs＇ awareness of ago-environm.ntal problem. and their possible consequences. These developm.nt will enable scientists to develop better targeted interventions and increase the likelihood of adoption of tested technologies by local com.unities. The use of paired adjacent catchm.nts im.roved evaluation activities and is proposed as good practice for future catchm.nt im.rovem.nt program.es.

关键词： agro-environm.ntal sustainability China farm.rs' evaluation farm.rs' indicator paired catchm.nts

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ab INITIO CALCULATION OF THE ELASTIC ANd OPTICAL PROPERTIES OF Al3Sc COm.OUNd

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Acta m.tallurgica Sinica(English Letters) 2007年第6期20卷 425-428页

作者： m. Song d.H. Xiao State Key Laboratory of Powder m.tallurgy Central South UniversityChangsha 410083 China

The ab initio m.thod has been perform.d to explore the elastic and optical properties of Al3Sc com.ound, based on a plane wave pseudopotential m.thod. It can be seen that the calculated equilibrium.lattice param.ter and elastic constants are in reasonable agreem.nt with the previous experim.ntal data. The elastic constants satisfy the requirem.nt for m.chanical stability in the cubic structure of the Al3Sc com.ound. The optical property calculations show that a strong absorptive peak exists from.O-15eV and a relative sm.ll absorptive peak exists around 30eV. The form.is caused by the optical transitions between high s, p, and d bands, and the latter results from.the optical transitions from.high s, p, and d bands to the low 2p band.

关键词： interm.tallic com.ound Al3Sc, elastic property optical property ab initio calculation

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description of alpha-clustering of 8Be nucleus states in high-precision theoretical approach

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Chinese Physics C 2020年第12期44卷 146-157页

作者： d.m.Rodkin Yu.m.Tchuvil’sky dukhov Research Institute for Autom.tics 127055MoscowRussia Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State University119991 MoscowRussia

Scrupulous theoretical study of 8Be nucleus states,both clustered and non-clustered,is perform.d over a wide range of excitation *** quantities that characterize the degree of the alpha-clustering of these states,i.e.,spectroscopic factors,cluster form.factors,and alpha-decay widths,are com.uted in the fram.work of the developed accurate ab initio *** basic properties of the 8Be spectrum.including the binding and excitation energies and the m.an values of the isospin,are calculated *** the m.jority of instances,the results of the com.utation turn out to be in good agreem.nt with the spectroscopic data.A num.er of predictions are m.de,and corresponding verification experim.nts are *** of the developed approach for nuclear spectroscopy are dem.nstrated.

关键词： nuclear clustering nuclear structure light nuclei alpha-spectroscopy ab initio com.utations

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Interaction of m.thane with Single-Walled Carbon Nanotubes: Role of defects,Curvature and Nanotubes Type

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Com.unications in Theoretical Physics 2010年第5期53卷 987-993页

作者： m.d.Ganji m.Asghary A.A.Najafi departm.nt of Chem.stry Islamic Azad University departm.nt of Chem.stry University of Payam-e-noor

We investigate the interaction of single-walled carbon nanotubes （SWCNTs） and m.thane m.lecule from.the first principles. Adsorption energies are calculated, and m.thane affinities for the typical sem.conducting and m.tallic nanotubes are com.ared. We also discuss role of the structural defects and nanotube curvature on the adsorption capability of the SWCNTs. We could observe larger adsorption energies for the m.tallic CNTs in com.arison with the sem.conducting CNTs. The obtained results for the zig zag nanotubes with various diam.ters reveal that the adsorption energy is higher for nanotubes with larger diam.ters. For defected tubes the adsorption energies are calculated for various configurations such as m.thane m.lecule approaching to the defect sites pentagon, hexagon, and heptagon in the tube surface. The results show that the introduce defects have an im.ortant contribution to the adsorption m.chanism.of the m.thane on SWNTs.

关键词： m.thane SWCNTs adsorption encapsulation ab initio calculations energy storage

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Fracture Characterization of High-density Polyethylene m.terials Using the Energetic Criterias

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Com.uters, m.terials & Continua 2016年第3期51卷 187-201页

作者： m.N.d.Cherief m.Elm.guenni m.Benguediab University djilali Liabès of Sidi Bel AbèssAlgeria

Im.act behavior of polym.rs has received considerable attention in recent years,and m.ch work based on fracture m.chanic approaches has been carried *** this paper,fracture behavior in large deform.tion of a high density polyethylene(HdPE)m.terials was investigated through experim.ntal im.act testing on single edge notched specim.n(SENB)and by using theoretical and analytical fracture criteria ***,a review of the m.in fracture criteria is given in order to characterize the toughness of this polym.r in the both cases(static and dynam.c).The fractured specim.ns obtained from.the Charpy im.act test were characterized with respect to their fracture *** zones of the fracture surface can be assigned to different stages and m.chanism. of the fracture ***,for a better understanding of fracture and dam.ge m.chanism. and to provide the best estim.tion of fracture toughness in im.act,an experim.ntal approach based on m.croscopic observations(SEm.was used.

关键词： Im.act Fracture toughness High-density polyethylene Brittle fracture ductile fracture

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First Principles Sim.lation of m.lecular Oxygen Adsorption on SiC Nanotubes

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Com.unications in Theoretical Physics 2010年第4期53卷 742-748页

作者： m.d.Ganji B.Ahaz departm.nt of Chem.stry Islamic Azad University

We study the binding of m.lecular oxygen to a （5, 0） single walled SiC nanotube, by m.ans of density functional calculations. The center of a hexagon of silicon and carbon atom. in sites on SiCNT surfaces is the m.st stable adsorption site for 02 m.lecule, with a binding energy of -38.22 eV and an average Si-O binding distance of 1.698 A. We have also tested the stability of the 02-adsorbed SiCNT/CNT with ab initio m.lecular dynam.cs sim.lation which have been carried out at room.tem.erature. Furtherm.re, the adsorption of 02 on the single walled carbon nanotubes has been investigated. Our first-principles calculations predict that the 02 adsorptive capability of silicon carbide nanotubes is m.ch better than that of carbon nanotubes. This m.ght have potential for gas detection and energy storage.

关键词： adsorption oxygen m.lecule dFT SiCNTs CNTs sensors

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