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Biogenic synthesis of silver nanoparticles using Persicaria odorata leaf extract: Antibacterial, cytocompatibility, and in vitro wound healing evaluation

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Particuology 2022年第11期70卷 10-19页

作者： Faridah Aminullah Lubis Nik ahmad Nizam NikMalek Nor Suriani sani Khairunadwa Jemon Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-ISIR)Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia

Biogenic synthesis of silver nanoparticles(b-AgNPs)utilising plant extract has gained the interest of researchers due to the environmentally friendly and cost-effective ***,the extent of its application in the biomedical field remains *** study evaluates the antibacterial,cytocompatibility,and wound healing activities of synthesised AgNPs using Persicaria odorata leaves extract(PO-AgNPs).The formation of PO-AgNPs was observed by visual colour changes and verified by ultraviolet-visible(UV–vis)spectrophotometer,which revealed a surface plasmon resonance(SPR)at around 440 nm,and further confirmed by X-ray diffraction(XRD).Characterisation using Fourier transform infrared(FTIR)spectroscopy showed biomolecules from the leaves extract presented together on *** emission scanning electron microscope(FESEM)and high-resolution transmission electron microscopy(HR-TEM)images revealed PO-AgNPs nanospheres with diameters of 11±3 *** diffusion test(DDT)and minimum inhibitory concentration(MIC)analysis resulted in a dose-dependent inhibition of PO-AgNPs against tested Staphylococcus epidermidis and Methicillin-resistant Staphylococcus aureus(MRSA).These results were further corroborated by time-kill kinetic assay which revealed that PO-AgNPs were bactericidal against both strains 24 h *** and in vitro wound healing evaluation against normal human fibroblast cells,HSF 1184 inferred that PO-AgNPs are non-toxic to normal cells and able to enhance cell migration as compared to the non-treated ***,PO-AgNPs are biocompatible and possess antibacterial and wound healing capabilities that are useful in biomedical applications.

关键词： Silver nanoparticles Biosynthesis Antibacterial Cytocompatibility Wound healing

In situ biosynthesized silver nanoparticle-incorporated synthesized zeolite A using Orthosiphon aristatus extract for in vitro antibacterial wound healing

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Particuology 2022年第8期20卷 27-34页

作者： Muhammad Hariz Asraf Nor Suriani sani Craig Denver Williams Khairunadwa Jemon Nik ahmad Nizam Nik Maliek Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 SkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTM SkudaiJohorMalaysia University of Wolverhampton Wulfuna StreetWolverhampton WV11SBEnglandUK Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-SIR).Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia

The capability of synthesized zeolite A(SZ)to immobilize Ag ions(Ag-SZ)and Ag nanoparticles(AgNp-SZ)were comparatively studied.A novel approach of in situ biosynthesized AgNP-incorporated synthesized zeolite A(AgNp-SZ)was synthesized at an optimum volume of 0.4mL of the Orthosiphon aristatus(***)leaves plant extract(5%)using an in situ *** comparison,Ag-Sz was produced by loading the synthesized zeolite with Ag *** synthesized materials were characterized for their morphologies and *** characterization analysesvalidate thathe biosynthesized AgNP(<100 nm)using *** leaves extract was incorporated into the zeolite *** antibacterial testing confirmed that these materials have antibacterial activity against Escherichia coliATCC11229 and Staphylococcus aureus ATCC ***/MBC analysis demonstrated that in 0.9%saline solution,AgNP-SZ had higher antibacterial activity than *** in vitro cell viability and migration assays were further examined towards human skin fibroblast cells HSF *** show that the materials are not cytotoxicto HSF1184,and the biosynthesized AgNP-SZ promotes cell migration and proliferation higher than *** research proved that the biocompatible antibacterial wound healing agent of AgNP-SZ can be synthesized using an in situ approach where the reduction process of Ag ions in the zeolite Acan be performed using plant extract.

关键词： Zeolite Orthosiphon aristatus Biosynthesis Silver nanoparticles Antibacterial In vitro wound healing

Antibacterial, cytotoxicity and wound healing assessments of amine-functionalised zeolite Y

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Particuology 2019年第4期17卷 116-123页

作者： Muhammad Hariz Asraf Nik ahmad Nizam Nik Malek Khairunadwa Jemon Nor Suriani sani Mustapha Salisu Muhammad Department of Biosciences Faculty of Science Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia Centre for Sustainable Nanomaterials (CSNano) Ibnu Sina Institute for Scientific and Industrial Research (IS1-ISIR) Universiti Teknologi Malaysia 81310 UTMJohor Malaysia Office of Deputy Vice Chancellor (Research and Innovation) Universiti Teknologi Malaysia 81310 UTM Skudai Johor Malaysia

The antibacterial activities,cytotoxicity,and wound healing of amine(3-aminopropyltriethoxysilane (APTES))-functionalised zeolite Y against normal human fibroblast cells were *** characterisation of unmodified and amine-functionalised zeolites Y (Z,ZA 0.04,ZA 0.4,and ZA 0.6) by Fourier transform infrared spectroscopy,X-ray powder diffraction,and energy dispersive X-ray analysis proved that the APTES molecules were grafted onto the zeolite Y surface without distorting its framework *** amine-functionalised zeolite Y samples possessed antibacterial activities against several ATCC bacteria that were correlated with the increased amount of APTES on the zeolite Y ***,when a higher concentration of APTES was grafted on the zeolite Y,higher cytotoxicity was observed against the fibroblast *** the ZA 0.6 sample (zeolite Y functionalised with 0.6 M of APTES) had higher antibacterial activity,it was cytotoxic to the ***,the selection of an antibacterial agent for human treatment purposes must also consider its cytotoxicity effect against human cells to ensure it is biocompatible.

关键词： Zeolite Y Amine functionalised zeolite Functionalisation Antibacterial agent Cytotoxicity

Analysis of optoelectronic properties of TiO_2 nanowiers/Si heterojunction arrays

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Chinese Physics B 2014年第10期23卷 469-471页

作者： Saeideh Ramezani sani Department of Physics Roudehen Branch Islamic Azad University

The optoelectronic properties of n-TiO2NW/p-Si heterojunction fabricated by depositing TiO2 nanowires on a p-Si substrate are studied. Under excitation at a wavelength of 370 nm, the TiO2 nanowires produce a light emission at 435 nm due to the emission of free excitons. The I-V characteristics are measured to investigate the heterojunction effects under the dark environment and ultraviolet （UV） illumination, n-TiOzNW/p-Si has a p-n junction formed in the n-TiOz/p-Si beterojunction. TiO2NW/Si photodiode produces a pbotocurrent larger than dark current under UV illumination. It is observed that UV photons are absorbed in TiO2 and the heterojunction shows a 0.034-A/W responsivity at 4-V reverse bias.

关键词： TiO2 nanowires photoresponse I-V characteristics heterojunction

Performance evaluation of laterite soil embankment stabilized with bottom ash,coir fiber,and lime

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Journal of Mountain Science 2024年第7期21卷 2334-2351页

作者： Yunusa Hamdanu sani Amin EISAZADEH School of Civil Engineering and Technology Sirindhorn International Institute of TechnologyThammasat UniversityPathum Thani 12120Thailand

In tropical regions,heavy rainfall induces erosion and shallow landslides on road ***-based stabilization methods,common in these regions,contribute to climate change due to their high carbon *** study explored the potential application of coir fiber-reinforced laterite soil-bottom ash mixtures as embankment materials in the *** objective is to enhance engineered embankment slopes'erosion resistance and stability while offering reuse options for industrial *** study examined various mix designs for unconfined compressive strength(UCS)and permeability,utilizing 30%bottom ash(BA)and 1%coir fiber(CF)with varying sizes ranging from 10 to 40 mm,6%lime,and laterite soil(LS),followed by microstructural *** results demonstrate that the compressive strength increases as the CF length increases to 25 *** contrast,permeability increases continuously with increasing CF ***-treated mixtures exhibit superior short-and long-term strength and reduce permeability owing to the formation of cementitious materials,as confirmed by microstructural analyses.A lab-scale slope box was constructed to evaluate the surface erosion of the stabilized laterite soil *** on the rainfall simulation results,the LS-BA-CF mixtures show better resistance to erosion and deformation compared to untreated LS,especially when lime is added to the top *** study provides insights into a sustainable and cost-effective approach for slope stabilization using BA and CF,offering a promising solution for tropical regions susceptible to surface erosion and landslides.

关键词： Lateritic soil Bottom ash Coir fiber lime Unconfined compressive strength Permeability FESEM/EDS Rainfall simulation tests

Anthropogenic disturbance of aquatic biodiversity and water quality of an urban river in Penang, Malaysia

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Water Science and Engineering 2023年第3期16卷 234-242页

作者： Nur Azalina Suzianti Feisal Noor Haziqah Kamaludin Muhammad Firdaus Abdullah sani Dayang Khairulnisa Awang ahmad Mohd Azwan ahmad Nur Faiza Abdul Razak Tengku Nilam Baizura Tengku Ibrahim Department of Environmental Health Faculty of Health SciencesMAHSA UniversityBandar Saujana Putra42610 JenjaromMalaysia Center of Environmental Health&Safety Faculty of Health SciencesUniversiti Teknologi MARA42300 Puncak AlamMalaysia NaturePRO Services Port Dickson71000 Negeri SembilanMalaysia Department of Environmental Health Faculty of Health SciencesUniversiti Teknologi MARACawangan Pulau PinangKampus Bertam13200 Pulau PinangMalaysia

Malaysia's rapid economic and demographic development have placed negative pressure on its water supplies and the quality of the Juru River, which is close to the nation's capital and its major source of water. Healthy aquatic ecosystems are supported by physicochemical properties and biological diversity. This study evaluated the anthropogenic impacts on aquatic biodiversity, especially plankton, fish, and macrobenthos, as well as the water quality of the Juru River in the Penang area. Aquatic biodiversity and river water parameters were collected from ten sampling stations along the Juru River. Seven variables were used to assess the physicochemical environment: pH, temperature, total suspended solids (TSS), salinity, dissolved oxygen (DO), biochemical oxygen demand (BOD), and chemical oxygen demand. At each sampling station, the total number of plankton, fish, and macrobenthic taxa were counted and analyzed. The relationships between the physicochemical parameters and aquatic biodiversity were investigated with biotypological analysis, principal component analysis, hierarchical cluster analysis, and linear regression analysis. These analyses showed that the richness and diversity indices were generally influenced by salinity, temperature, TSS, BOD, and pH. The data obtained in this study supported the bioindicator concept. The findings, as they related to scientifically informed conservation, could serve as a model for Juru River management, as well as for river management throughout Malaysia and other tropical Asian countries.

关键词： Anthropogenic disturbance Aquatic biodiversity River water quality Urban river Hierarchical cluster analysis

Enhanced two-loop model predictive control design for linear uncertain systems

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Journal of Systems Engineering and Electronics 2021年第1期32卷 220-227页

作者： Mohammad-Ghassem FARAJZADEH-DEVIN Seyed Kamal HOSSEINI sani Department of Electrical Engineering Ferdowsi University of MashhadMashhad 1696700Iran

Model predictive controllers(MPC)with the two-loop scheme are successful approaches practically and can be classified into two main categories,tube-based MPC and MPCbased reference governors(RG).In this paper,an enhanced twoloop MPC design is proposed for a pre-stabilized system with the bounded uncertainty subject to the input and state *** proposed method offers less conservatism than the tube-based MPC methods by enlarging the restricted input *** to the MPC-based RGs,the investigated method improves tracking performance of the pre-stabilized system while satisfying the ***,the robust global asymptotic stability of the closed-loop system is guaranteed in a novel procedure with terminal constraint *** of the proposed method on a servo system shows its effectiveness in comparison to the others.

关键词： model predictive control(MPC) robust control cascade control constraint satisfaction

Genome wide identification and characterization of MAPK genes reveals their potential in enhancing drought and salt stress tolerance in Gossypium hirsutum

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Journal of Cotton Research 2022年第3期5卷 261-273页

作者： SADAU Salisu Bello MEHARI Teame Gereziher ahmad Adeel TAJO sani Muhammad IBRAHIM sani IQBAL Muhammad Shahid ELASAD Mohammed ZHANG Jingjing WEI Hengling YU Shuxun State Key Laboratory of Cotton Biology Institute of Cotton ResearchChinese Academy of Agricultural SciencesAnyangHenan 455000China Key Laboratory of Biology and Genetic Improvement of Oil Crops Ministry of AgricultureOil Crops Research InstituteChinese Academy of Agricultural SciencesWuhan 430062China Department of Science and Technology Education Bayero University KanoP.O.Box 3011KanoNigeria Agricultural Research Corporation(ARC) P.O.Box 126Wad MedaniSudan.

Background:The cotton crop is universally considered as protein and edible oil source besides the major contributor of natural fiber and is grown in tropical and subtropical regions around the world Unpredicted environmental stresses are becoming significant threats to sustainable cotton production,ultimately leading to a substantial irreversible economic ***-activated protein kinase(MAPK)is generally considered essential for recognizing environmental stresses through phosphorylating downstream signal pathways and plays a vital role in numerous biological ***:We have identified 74 MAPK genes across cotton,41 from ***,19 from ***,whereas 14 have been identified from *** MAPK gene-proteins have been further studied to determine their physicochemical characteristics and other essential *** this perspective,characterization,phylogenetic relationship,chromosomal mapping,gene motif,cis-regulatory element,and subcellular localization were carried *** on phylogenetic analysis,the MAPK family in cotton is usually categorized as A,B,C,D,and E *** to the results of the phylogenic relationship,cotton has more MAPKS genes in Clade A than Clade *** cis-elements identified were classified into five groups(hormone responsiveness,light responsiveness,stress responsiveness,cellular development,and binding site).The prevalence of such elements across the promoter region of these genes signifies their role in the growth and development of *** GHMAPK genes(GH_A07G1527,GH_D02G1138,GH_D03G0121,GH_D03G1517,GH_D05G1003,GH_D11G0040,and GH_D12G2528)were selected,and specific tissue expression and profiling were performed across drought and salt *** expressed that six genes were upregulated under drought treatment except for GH_D11G0040 which is *** all the seven genes have been upregulated at various hours of salt stress ***:RNA sequence and qPCR results showe

关键词： Cotton MAPK gene Drought stress Salt stress

Using Syntactic-Based Kernels for Classifying Temporal Relations

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Journal of Computer Science & Technology 2011年第1期26卷 68-80页

作者： Seyed Abolghasem Mirroshandel Gholamreza Ghassem-sani Mahdy Khayyamian Department of Computer Engineering Sharif University of Technology

Temporal relation classification is one of contemporary demanding tasks of natural language processing. This task can be used in various applications such as question answering, summarization, and language specific information retrieval. In this paper, we propose an improved algorithm for classifying temporal relations, between events or between events and time, using support vector machines （SVM）. Along with gold-standard corpus features, the proposed method aims at exploiting some useful automatically generated syntactic features to improve the accuracy of classification. Accordingly, a number of novel kernel functions are introduced and evaluated. Our evaluations clearly demonstrate that adding syntactic features results in a considerable improvement over the state-of-the-art method of classifying temporal relations.

关键词： temporal relation classification information retrieval text mining support vector machines kernel function