检索结果-南通市图书馆

Study of high throughput screening for 5 - LO inhibitor and its application

在线全文

cnki会议

学校读者我要写书评

暂无评论

Study of high throughput screening for 5 - LO inhibitor and ...

首届中医药发展国际论坛、首届中医药防治艾滋病国际研讨会和全国中医药科研院所长联谊会

作者： Lin Li, Zhang Li, Du Guan - hua, Qiao Yan - Jiang, Liu Jian - xun Xiyuan Hospital, China academy of TCM, Beijng 100091 College of Traditional chinese Pharmacy, {2. university of chinese Medicine, {2. 100102.National center for Pharmaceutical Screening, Institute of Materia Medica, chinese academy of Medical sciences, {2. (100050)

AIM: To develop a 5 - LO inhibitor screening model which can screen the anti - in- flammation ***: Enzymes and medicine were first incubated in a 384 - well *** drug anti - inflammation activity is assayed colorimetrically by monitoring the appearance of oxidized TMPD at 590 ***: NDGA shows that this model can be used to screen 5 - LO *** TCMs was screened, none of them showed a high *** of them exhibit a moderate inhibition and Semen artemisia halodendron show the highest inhibition CONCLUSION: The 5 - LO inhibitor screening model is easy to perform and suitable to high throughout screening.

关键词： 5-lipoxygenase inhibitors TCMs anti-inflammatory activity

Cloning and functional analysis of the sequences flanking mini-Tn5 in the magnetosomes deleted mutant NM4 of Magnetospirillum gryphiswaldense MSR-1

在线全文

cnki会议

学校读者我要写书评

暂无评论

Science China(Life sciences) 2005年第6期48卷 574-584页

作者： LI Feng1,2. LI Ying1, JIANG Wei1, WANG Zhenfang1 & LI Jilun1 1. State Key Laboratory for Agro-biotechnology and Department of Microbiology, China Agricultural university, beijing 100094, China 2. Department of Biology, Huaibei Coal Industry Teachers’ College, Huaibei 2.5000, China 1. State Key Laboratory for Agro-biotechnology and Department of Microbiology China Agricultural University 100094 Beijing China 2. Department of Biology Huaibei Coal Industry Teachers’ College 235000 Huaibei China

A magnetosome deleted mutant NM4 of Magnetospirillum gryphiswaldense MSR-1 was generated by mini-Tn5 transposon mutagenesis, and a 5045-bp fragment flanking mini-Tn5 in NM4 was cloned by Anchored PCR. Sequencing analysis showed that this fragment involved six putative open reading frames (ORFs); the mini-Tn5 was inserted into ORF4. Functional complementary test indicated that the 5045-bp fragment was required for biosynthesis of mag-netosomes in M. gryphiswaldense MSR-1. The protein encoded by ORF4 had 2.% of identity with the chemotaxis protein CheYIII of Caulobacter crescentus CB15, and the protein encoded by ORF4 contained a conserved signal receiver domain that can receive the signal from the sensor partner of the bacterial two-component systems. It was suggested that the protein en-coded by ORF4 may take part in the signal transduction relating to biosynthesis of magneto-somes.

关键词： Magnetospirillum gryphiswaldense, magnetosome deleted mutant, gene cloning, functional analysis.

紫色土丘陵区农田源头沟渠一氧化氮排放的季节差异及影响因素

在线全文

学校读者我要写书评

暂无评论

环境科学 2018年第4期39卷 1952-1961页

作者：田琳琳任光前朱波中国科学院水利部成都山地灾害与环境研究所成都610041 中国科学院山地表生过程与生态调控重点实验室成都610041 中国科学院大学北京100049 江苏大学环境与安全工程学院镇江212013

农田源头沟渠是农田养分迁移的重要水文通道和非常活跃的氮转化场所.本研究以紫色土丘陵区农田源头沟渠为对象,在2.14年12.~2.15年11月,采用静态箱-化学发光法对其一氧化氮(NO)排放开展原位观测.结果表明,有自然植被覆盖的农田源头沟... 详细信息

农田源头沟渠是农田养分迁移的重要水文通道和非常活跃的氮转化场所.本研究以紫色土丘陵区农田源头沟渠为对象,在2.14年12.~2.15年11月,采用静态箱-化学发光法对其一氧化氮(NO)排放开展原位观测.结果表明,有自然植被覆盖的农田源头沟渠生态系统(V)中的NO年累积排放量为14.17 g·(hm^2.a)^(-1),而无自然植被覆盖的对照处理(NV,代表沟渠中的沉积物-水界面系统)则为-0.4 g·(hm^2.a)^(-1).总体而言,沟渠生态系统的年综合排放通量是11.2. g·(hm^2.a)^(-1),全年平均排放通量为0.13μg·(m^2.h)^(-1).农田源头沟渠仅在夏季是NO的排放源,且夏季NO累积排放量显著高于(P<0.05)春季、秋季或冬季.沟渠上覆水NO_3^--N浓度和温度是影响NO排放季节变化的主要控制因素.同时,沟渠生态系统中植物存在可显著提高所观测的NO排放通量,但对全年NO累积排放量无显著影响.

关键词：沟渠生态系统一氧化氮间接排放硝态氮小流域氮循环温度

在线全文

学校读者我要写书评

暂无评论

髋关节MRI检查及诊断专家共识

中华放射学杂志 2024年第1期58卷 18-24页

作者：中华医学会放射学分会骨关节学组袁慧书王奇政郎宁不详北京大学第三医院放射科北京100191

髋关节MRI在临床诊疗中应用广泛,能够评估髋关节骨质、关节软骨及周围软组织解剖细节,但当前髋关节MRI的适应证、技术流程及影像评价缺乏规范标准,制约了髋关节疾病的规范化诊疗。为推动髋关节MRI在我国的规范化应用,中华医学会放射学... 详细信息

髋关节MRI在临床诊疗中应用广泛,能够评估髋关节骨质、关节软骨及周围软组织解剖细节,但当前髋关节MRI的适应证、技术流程及影像评价缺乏规范标准,制约了髋关节疾病的规范化诊疗。为推动髋关节MRI在我国的规范化应用,中华医学会放射学分会骨关节学组组织专家参阅文献并结合临床实践,经过反复讨论和修订达成髋关节MRI检查及诊断共识。

关键词：磁共振成像髋关节专家共识

Ca-rich Garnet-Clinopyroxene Rocks at Hujialin in the Su-Lu Terrane(Eastern China):Deeply Subducted Arc Cumulates?

在线全文

学校读者我要写书评

暂无评论

Ca-rich Garnet-Clinopyroxene Rocks at Hujialin in the Su-Lu ...

中国科学院地质与地球物理研究所2.06学术年会

作者： Jian-Jun Yang~(1,2. 1 State Key Laboratory of Lithospheric Evolution,Institute of Geology and Geophysics,chinese academy of {2.,Beitucheng Xilu 19,P.O.Box 982.,beijing 10002.,China 2.The Key Laboratory of Continental dynamics.Department of Geology,Northwest university,Xi’an 710069, China

Layers of Ca-rich garnet-clinopyroxene rocks enclosed in a serpentinite body at Hujialin,in the Su-Lu terrane of eastern China,preserve igneous textures,relict spinel in garnet, and exsolution lamellae of Ca-rich garnet,ilmenite/magnetite,Fe-rich spinel,and also amphibole in *** terms of their major and trace element compositions,the studied samples form a trend from arc cumulates towards Fe-Ti *** augite compositions plot on the trend for clinopyroxene in arc *** data suggest that the rocks crystallised from mantle-derived magmas differentiated to various extents beneath an *** Ca-rich garnet + diopside assemblage is inferred to have formed by compressing Ca-rich augite,whereas the relatively Mg-rich cores of garnet porphyroblasts may have formed at the expense of *** protolith cumulates were subducted from near the crust-mantle boundary(c.1 GPa) deep into the upper mantle(4.8±0.6 GPa and 750±50℃).Negatively sloped PT paths for the garnet-clinopyroxene rocks and the corollary of corner flow induced subduction of mantle wedge peridotite are not supported by the available *** with,or without,decompression of the cumulates after the igneous stage likely occurred prior to deep subduction.

关键词： arc cumulates Ca-rich garnet garnet-clinopyroxene rocks Su-Lu terrane UHP metamorphism

New Isoflavonoside from Bupleurum Scorzonerifolium

在线全文

cnki会议

学校读者我要写书评

暂无评论

chinese Chemical Letters 1998年第1期9卷 71-73页

作者： Li TAN Yu Ying ZHAO Bin WANG Ru Yi ZHANG (Department of Phytochemistry, beijing Medical university, beijing 100083)Guang Zhong TU(beijing Institute of Microchemistry, beijing 100091) beijing Med Univ Dept Phytochem Beijing 100083 Peoples R China

A new isoflavonoside, 7-hydroxy-4'-methoxy-isoflavonone-7-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside was isolated from roots of Bupleurum scorzonerifolium Willd., and named as saikoisoflavonoside A. The st... 详细信息

关键词： Bupleurum scorzonerifolium isoflavonoside saikoisoflavonoside A

Photonic integrated technology for multi-wavelength laser emission

在线全文

学校读者我要写书评

暂无评论

Science Bulletin 2011年第Z2期 3064-3071页

作者： CHEN XiangFei 1 , LIU Wen 2., AN JunMing 3 , LIU Yu 3 , XU Kun 4 , WANG Xin 3 , LIU JianGuo 3 , JI YueFeng 4 & ZHU NingHua 3* 1 National Laboratory of Microstructures, Nanjing university, Nanjing 2.0093, China 2.State Key Laboratory of Optical Communication Technologies and Networks, Wuhan Research Institute of Posts & Telecommunications, Wuhan 430074, China 3 Institute of Semiconductors, chinese {2. of sciences, beijing 100083, China 4 Institute of Optical Communication and Optoelectronics, beijing university of Posts and Telecommunications, beijing 100876, China

We summarized the design, fabrication challenges and important technologies for multi-wavelength laser transmitting photonic integration. Technologies discussed include multi-wavelength laser arrays, monolithic integration and modularizing coupling and packaging. Fabrication technique requirements have significantly declined with the rise of reconstruction-equivalent-chirp and second nanoimprint mask technologies. The monolithic integration problem between active and passive waveguides can be overcome with Butt-joint and InP array waveguide grating technologies. The dynamic characteristics of multi-factors will be simultaneously measured with multi-port analyzing modules. The performance of photonic integration chips is significantly improved with the autoecious factors compensation packaging technique.

关键词： photonic integration laser multi-wavelength

Studies on Identification of Wheat-Barley 2. Alien Substitution Lines

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Studies on Identification of Wheat-Barley 2H Alien Substitut...

吉林省第六届生命科学大型学术报告会

作者： YUAN Ya-Ping~1 CHEN Xiao~2.ZOU Hong-Da~1 WU-Ying~1 SUN Wei~1 (~1 College of Plant Science,Jilin university,Changchun,130062.China ~2.ey Laboratory of Agricultural Ministry for Crop Genetics and Breeding.Institute of Crop Breeding and Cultivation,chinese {2. of Agricultural sciences,beijing,100081,China)

The genetic constitution of fifteen materials derived from the cross CS (Triticum aestivum ***. chinese Spring)x Betzes (Hordeum vulgate ***) was analyzed,and six disomic alien substitution lines were screened by *** chromosome configurations in pollen mother cells at meiotic metaphase I(PMCs M I) of F from each disomic substitution line respectively crossed with double ditelocentric lines 2.,2. and 2. of chinese Spring were observed,and a set of wheat-barley disomic alien substitution lines 2.(A),2.(B) and 2.(D) were *** RFLP analysis with the probe psr131 on the short arm of wheat homeologous group 2.combining with four restriction enzymes were carded *** results indicated that the probe psr131 could be used as molecular marker to tag the barley chromosome *** barley chromosome 2. had good genetic compensation ability for wheat chromosome 2. and 2. in vitality and other agronomic *** result of testing seed was that the wheat appearance starch quality had been changed from the half-farinaceous of CS to the half-cutin of substitution lines by transferring the barley chromosome 2. to wheat.

关键词： wheat barley substitution line Genomic in situ hybridization (GISH) RFLP

Improving dispersion of multiwalled carbon nanotubes in polylactide via grafting five hydroxyl-terminated polylactide

在线全文

cnki会议

学校读者我要写书评

暂无评论

Improving dispersion of multiwalled carbon nanotubes in poly...

4th International Symposium on Engineering Plastics

作者： Zhaohua XU Zhigang WANG~* CAS Key Laboratory of Engineering Plastics beijing National Laboratory for Molecular sciences Institute of Chemistry {2. academy of sciences beijing 100190 China

＜正＞Polylactide（PLA）,as a biodegradable polymer,is drawing increasing attention due to academic and commercial ***,the preparation of polymer nanocomposites with carbon nanotubes（CNTs） has already been proved to be an effective way to modify the polymers[1-5].Therefore,the combination of PLA and CNTs is expected to form nanocomposites with enhanced ***,the

关键词：