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The evolution and morphological stability of a spherical crystal

Science china(Technological Sciences) 2008年第3期51卷 225-243页

作者： CHEN MingWen1,2, WANG ZiDong2 & XU JianJun3,4 1 School of Applied Sciences, university of Science and Technology beijing, beijing 100083, china 2 School of Materials Science and Engineering, university of Science and Technology beijing, beijing 100083, china 3 School of Mathematical Sciences, Nankai university, Tianjin 300071, china 4 department of Mathematics and Statistics, McGill university, Montreal H3A 2K6, Canada School of Applied Sciences University of Science and Technology Beijing Beijing China School of Materials Science and Engineering University of Science and Technology Beijing Beijing China School of Mathematical Sciences Nankai University Tianjin China department of Mathematics and Statistics McGill University Montreal Canada

The growth model of a spherical crystal in the undercooled melt including the surface energy, interfacial kinetics and convective flow is established. The effect of the convective flow induced by a small far field flow on the evolution and morphological stability of the interface of the spherical crystal is studied. The interface shape of the spherical crystal, which is affected by the far field flow, and the dispersion relation of the growth rate of amplitude of the perturbed interface are derived. It is shown that the convection induced by the far field flow makes the interface of the growing spherical crystal further grow in the upstream direction of the far field flow and inhibit growth in the downstream direction; the interface of the decaying spherical crystal further decays in the upstream direction and inhibits decay in the downstream direction. The theoretical result suggests that both the growth of the sphere in the upstream direction and the decay of the sphere in the downstream direction make the spherical crystal tend to evolve into an oval; the morphological stability of the interface depends on a certain radius R c such that the spherical crystal is unstable when its radius is greater than R c and stable when its radius is less than R c . The surface energy and interfacial kinetics have strong stabilizing effects on the growth of the spherical crystal. In the meantime interfacial kinetics is a table factor of the interface when the interface of the sphere is growing; it is an unstable factor of the interface when the interface is decaying.

关键词： solid-liquid interface spherical crystal convective flow crystal growth morphological stability

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Information flow and controlling in regularization inversion of quantitative remote sensing

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Science china Earth Sciences 2005年第1期48卷 74-83页

作者： YANG Hua, XU Wangli, ZHAO Hongrui, CHEN Xue & WANG Jindi Research Center for Remote Sensing and GIS, School of Geography, beijing Normal university, State Key Laboratory of Remote Sensing Science, beijing Key Laboratory for Remote Sensing of Environment and Digital Cities, beijing 100875, china department of Mathematics, beijing Normal university, beijing 100875, china Research Center for Remote Sensing and GIS School of Geography Beijing Normal University State Key Laboratory of Remote Sensing Science Beijing Key Laboratory for Remote Sensing of Environment and Digital Cities Beijing China department of Mathematics Beijing Normal University Beijing China

In order to minimize uncertainty of the inversed parameters to the largest extent by making full use of the limited information in remote sensing data, it is necessary to understand what the information flow in quantitative remote sensing model inversion is, thus control the information flow. Aiming at this, the paper takes the linear kernel-driven model inversion as an example. At first, the information flow in different inversion methods is calculated and analyzed, then the effect of information flow controlled by multi-stage inversion strategy is studied, finally, an information matrix based on USM is defined to control information flow in inversion. It shows that using Shannon entropy decrease of the inversed parameters can express information flow more properly. Changing the weight of a priori knowledge in inversion or fixing parameters and partitioning datasets in multi-stage inversion strategy can control information flow. In regularization inversion of remote sensing, information matrix based on USM may be a better tool for quantitatively controlling information flow.

关键词： regularization inversion, information flow, Shannon entropy decrease, information matrix.

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Distinct Pattern of Human Vδ1 γδ T Cells Recognizing MICA

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Cellular & Molecular Immunology 2005年第4期2卷 253-258页

作者： Jianqiang Li~1 Lianxian Cui~1 Wei He~(1,2) ~1department of Immunology,Institute of basic Medical Sciences,Chinese Academy of Medical Sciences and School of basic Medicine,Peking union Medical college,5 Dong Dan San Tiao,beijing 100005,china department of Immunology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences and School of Basic Medicine Peking Union Medical College Beijing 100005 China.

γδT cells represent one unique recognition pattern,the limited recognition,which distinguishes from the specificrecognition for αβT cells and pattern recognition for macrophages.Vδ1 γδT cell is the major subset of human γδT cells,which predominates in mucosal tissue including the intestinal ***,a few antigens thathuman Vδ1TCR can recognize have been *** them,MHC class I chain-related molecules A (MICA)have been studied most *** Vδ1TCR,MICA is also the ligand of NKG2D,a C-type lectin-likeactivating *** human,only Vδ1 cells can simultaneously express both types of receptors of MICAwhile NK cells,αβT cells and other subsets of γδT cells likewise express *** the precisemechanisms are still enigmatic,this distinct pattern of Vδ1 cells recognizing MICA predicts unique biologicalsignificance of Vδ1 cells in immune *** years,some progresses have been made in this *** thisreview we summarize the related reports and put forward some novel views based on our group’s ***& Molecular Immunology.2005;2(4):253-258.

关键词： Vδ1TCR MICA NKG2D γδ T cell

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Chinese expert consensus on refined diagnosis,treatment,and management of advanced primary liver cancer(2023 edition)

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肝脏研究（英文） 2024年第2期8卷 61-71页

作者： Xiufeng Liu Feng Xia Yue Chen Huichuan Sun Zhengqiang Yang Bo Chen Ming Zhao Xinyu Bi Tao Peng Aizier Ainiwaer Zhiwen Luo Fusheng Wang Yinying Lu National Clinical Research Center for Infectious Diseases Society of Hepatology,beijing Medical Association Translational Medicine Branch,china Association of Gerontology and Geriatrics department of Medical Oncology Bayi Hospital Affiliated to Nanjing Chinese Medical University NanjingJiangsuChina department of Hepatobiliary Surgery Southwest HospitalArmy Medical University ChongqingChina Senior department of Hepatology The Fifth Medical Center of PLA General HospitalBeijingChina department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina department of Interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina department of Radiation Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina department of Minimally Invasive Interventional Therapy Liver Cancer Study and Service GroupSun Yat-sen University Cancer CenterGuangzhouGuangdongChina department of Hepatobiliary Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina department of Hepatobiliary Surgery The First Affiliated Hospital of Guangxi Medical UniversityNanningGuangxiChina Senior department of Infectious Diseases The Fifth Medical Center of PLA General HospitalBeijingChina Comprehensive Liver Cancer Center The Fifth Medical Center of PLA General HospitalBeijingChina

Hepatocellular carcinoma(HCC),commonly known as primary liver cancer,is a major cause of malignant tumors and cancer-related deaths in china,accounting for approximately 85％of all cancer cases in the *** guidelines have been used to diagnose and treat liver ***,these guidelines provide a broad definition for classifying advanced liver cancer,with an emphasis on a singular approach,without considering treatment options for individual ***,it is necessary to establish a comprehensive and practical expert consensus,specifically for china,to enhance the diagnosis and treatment of HCC using the Delphi *** classification criteria were refined for Chinese patients with HCC,and the corresponding optimal treatment regimen recommendations were *** recommendations took into account various factors,including tumor characteristics,vascular tumor thrombus grade,distant metastasis,liver function status,portal hypertension,and the hepatitis B virus replication status of patients with primary HCC,along with treatment *** findings and rec-ommendations provide detailed,scientific,and reasonable individualized diagnosis and treatment strategies for clinicians.

关键词： Hepatocellular carcinoma (HCC) Targeted therapy Immunotherapy Refined diagnosis and treatment Expert consensus

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Deficit of mitochondria-derived ATP during oxidative stress impairs mouse MII oocyte spindles

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Cell Research 2006年第10期16卷 841-850页

作者： Xiao Zhang~(1,2,*) Xue Qing Wu~(1,3,*) Shuang Lu~(4,5,6) Ying Lu Guo~1 Xu Ma~(4,5,6) ~1Peking university First Hospital,Institute of Urology of Peking university,beijing 100034,china ~2Reproductive and Genetic Center of Peking university First Hospital,beijing 100034,china ~3department of Obstetrics and Gynecology,Shanxi Medical university Second Hospital,Taiyuan 030000,china ~4Reproductive and Genetic Center of National Research Institute for Family Planning,beijing 100038,china ~5department of Genetics, Peking union Medical college, beijing 100038. china ~6 WHO Collaborative Center for Research in Human Reproduction,beijing 100038,china Peking university First Hospital Institute of Urology of Peking University Beijing China Reproductive and Genetic Center of Peking university First Hospital Beijing China department of Obstetrics and Gynecology Shanxi Medical University Second Hospital Taiyuan China Reproductive and Genetic Center of National Research Institute for Family Planning Beijing China department of Genetics Peking Union Medical College Beijing China WHO Collaborative Center for Research in Human Reproduction Beijing China

Although the role of oxidative stress in maternal aging and infertility has been suggested,the underlying mechanismsare not fully *** present study is designed to determine the relationship between mitochondrial functionand spindle stability in metaphase Ⅱ （MⅡ） oocytes under oxidative stress.MⅡ mouse oocytes were treated with H2O2inthe presence or absence of permeability transition pores （PTPs） blockers cyclosporin A （CsA）.In addition,antioxidantN-acetylcysteine （NAC）,F0/F1synthase inhibitor oligomycin A,the mitochondria uncoupler carbonyl cyanide 4-trifluoro-methoxyphenylhydrazone （FCCP） or thapsigargin plus 2.5 mM Ca2+(Th+2.5 mM Ca2+) were used in mechanistic *** analyses ofoocyte spindles and chromosomes were performed and mitochondrial membrane potential（Δψm）,cytoplasmic tree calcium concentration ([Ca2+]c) and cytoplasmic ATP content within oocytes were also *** a time- and H2O2dose-dependent manner,disruption of meiotic spindles was found after oocytes were treated withH2O2,which was prevented by pre-treatment with *** of H2O2led to a dissipation of Δψm,an increasein [Ca2+]cand a decrease in cytoplasmic ATP *** detrimental responses of oocytes to H20,treatment could beblocked by pre-incubation with *** to H2O2,both oligomycin A and FCCP dissipated Δψm,decreased cytoplas-mic ATP contents and disassembled MⅡ oocyte spindles,while high [Ca2+]calone had no effects on spindle *** conclusion,the decrease in mitochondria-derived ATP during oxidative stress may cause a disassembly of mouse MⅡoocyte spindles,presumably due to the opening of the mitochondrial PTPs.

关键词： spindle oxidative stress mitochondria permeability transition pore ATP

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Effects of Ganoderma lucidum polysaccharides on proliferation and cytotoxicity of cytokine-induced killer cells

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Acta Pharmacologica Sinica 2005年第9期26卷 1130-1137页

作者： Xiao-ling ZHU Zhi-bin LIN department of Pharmacology,School of basic Medical Science,Peking university Health Science Center,beijing 100083,china department of Pharmacology School of Basic Medical Science Peking University Health Science Center Beijing 100083 China

Aim:To study the effects(and the mechanisms thereof)of Ganoderma lucidumpolysaccharides(G/-PS)on the proliferation and the anti-tumor activity of cytokine-induced killer(CIK)cells,and to make use of CIK cells as a means to investigatethe interactions between Gl-PS and ***:CIK cells were preparedby using the standard protocol as a positive *** groups alsounderwent the standard protocol,except that Gl-PS(400 mg/L or 100 mg/L)wasadded and the dose of anti-CD3 and interleukin-2 they received was reduced by50% and 75%,*** negative controls,Gl-PS in the experimentalprotocol was replaced with soluble starch or methylcellulose(400 mg/L or 100 mg/L).CIK cell proliferation,cytotoxicity,and phenotype were determined by using theTrypan blue exclusion method,MTT assay,and flow ***:Bysynergizing cytokines,Gl-PS(400 mg/L or 100 mg/L)could decrease the amountof cytokine in lymphokine activated killer(LAK)cells and CIK cells culture,buthad no significant effect on the proliferation,cytotoxicity,or phenotype of LAKcells,or CIK cells induced by cytokines at higher doses alone,in which CIK cellsexpanded about 80-fold and the main effectors,CD3~+NK1.1~+ cells,expanded bymore than 15%.The cytotoxicity of CIK cells in experimental groups was 79.3%±4.7%,76.9%±6.8% versus the positive control 80.7%±6.8% against P815(P>0.05)and 88,9%±5.5%,84.7%±7.9% versus the positive control 89.8%±4.5% againstYAC-1(P>0.05).The activity of GI-PS could mostly be blocked by ***:GI-PS was shown to be a promising biological response modifier andimmune *** effect of GI-PS on CIK cells is possibly mediated prima-rily through complement receptor type 3.

关键词： Ganoderma lucidum polysaccharides cell proliferation cytotoxicity immunomodula-tion

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Multiparty quantum secret sharing of classical and quantum messages

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Progress in Natural Science:Materials International 2007年第1期17卷 26-31页

作者： CHEN Pan, DENG Fuguo and LONG Guilu ( Key Laboratory for Quantum Information and Measurements, and department of Physics, Tsinghua university, beijing 100084, china Key Laboratory of Beam Technology and Material Modification, MOE, Institute of Low Energy Nuclear Physics, and department of Material Science and Engineering, beijing Normal university, beijing 100875, china beijing Radiation Center, beijing 100875, china Key Laboratory for Atomic and Molecular Nano-Sciences, Tsinghua university, beijing 100084, china) Key Laboratory for Quantum Information and Measurements Department of Physics Tsinghua University Beijing 100084 China Key Laboratory of Beam Technology and Material Modification Beijing Normal University Beijing 100875 China Institute of Low Energy Nuclear Physics Department of Material Science and Engineering Beijing Normal University Beijing 100875 China beijing Radiation Center Beijing 100875 China Key Laboratory for Atomic and Molecular Nano-Sciences Tsinghua University Beijing 100084 China

A scheme for multiparty quantum secret sharing of classical and quantum messages is proposed by using entanglement swapping. This scheme can distribute not only the classical information but also the quantum informati... 详细信息

关键词： quantum secret sharing classical message quantum message EPR pair.

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Gas kinetic algorithm for flows in Poiseuille-like microchannels using Boltzmann model equation

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Science china(Physics,Mechanics & Astronomy) 2005年第4期48卷 496-512页

作者： LI Zhihui1,2, ZHANG Hanxin1 & FU Song2 ⒈ National Laboratory for CFD, Hypervelocity Aerodynamics Institute,china Aerodynamics Research and Development Center,Mianyang 621000,china 2.department of Engineering Mechanics,Tsinghua university,beijing 100084,china National Laboratory for CFD Hypervelocity Aerodynamics Institute China Aerodynamics Research and Development Center Mianyang China department of Engineering Mechanics Tsinghua University Beijing China

The gas-kinetic unified algorithm using Boltzmann model equation have been extended and developed to solve the micro-scale gas flows in Poiseuille-like micro-channels from Micro-Electro-Mechanical Systems (MEMS). The numerical modeling of the gas kinetic boundary conditions suitable for micro-scale gas flows is presented. To test the present method, the classical Couette flows with various Knudsen numbers, the gas flows from short microchannels like plane Poiseuille and the pressure-driven gas flows in two-dimensional short microchannels have been simulated and compared with the approximate solutions of the Boltzmann equation, the related DSMC results, the modified N-S solutions with slip-flow boundary theory, the gas-kinetic BGK-Burnett solutions and the experimental data. The comparisons show that the present gas-kinetic numerical algorithm using the mesoscopic Boltzmann simplified velocity distribution function equation can effectively simulate and reveal the gas flows in microchannels. The numerical experience indicates that this method may be a powerful tool in the numerical simulation of micro-scale gas flows from MEMS.

关键词： Boltzmann model equation, discrete velocity ordinate method, finite-difference scheme, Couette flow, Poiseuille flow, gas flow in short-microchannel.

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AR quivers,exceptional sequences and algorithms in derived Hall algebras

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Science china Mathematics 2010年第6期53卷 1609-1624页

作者： SHENG Jie department of Mathematical Sciences,Tsinghua university,beijing 100084,china department of Mathematical Sciences Tsinghua University Beijing China

Consider the canonical isomorphism between the positive part U+ of the quantum group Uq(g) and the Hall algebra H(Λ),where the semisimple Lie algebra g and the finite-dimensional hereditary algebra Λ share a Dynkin *** and Xiao have given two algorithms to decompose the root vectors into linear combinations of monomials of Chevalley generators of U+,respectively induced by the braid group action on the exceptional sequences of Λ-modules and the structure of the Auslander-Reiten quiver of Λ.In this paper,we obtain the corresponding algorithms for the derived Hall algebra DH(Λ),which was introduced by *** show that both algorithms are applicable to the lattice algebra and Heisenberg double in the sense of *** the new recursive formulae have the same flavor with the quantum Serre relations.

关键词： derived Hall algebra exceptional sequence AR quiver

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Chemiluminescence behavior of sodium hydrogen carbonate in the potassium permanganate-hydrogen peroxide reaction

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Science china Chemistry 2010年第8期53卷 1784-1792页

作者： CHEN Hui1,2,LU Chao1,LI RuiBo1,GUO GuangSheng1 & LIN Jin-Ming2 1State Key Laboratory of Chemical Resource Engineering beijing university of Chemical Technology,beijing 100029,china 2department of Chemistry,Tsinghua university,beijing 100084,china State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Beijing China department of Chemistry Tsinghua University Beijing China

Chemiluminescence (CL) phenomenon of hydrogen peroxide with potassium permanganate in the presence of sodium hydrogen carbonate was *** of the surfactant on the CL system were *** surfactants could effectively increase the CL *** scavengers and organic reagents such as nitro blue tetrazolium chloride (NBT),cytochrome c,sodium azide,ascorbic acid,thiourea,tert-butanol and dimethyl sulphoxide were used to study the emitting *** emission spectrum was recorded and the results showed that the maximal emission wavelengths of NaHCO3-H2O2-KMnO4 system were 440 and 634 *** mechanism was discussed based on electron spin resonance (ESR) spectra,fluorescence spectra and UV-vis absorption *** addition of rhodamine B or uranine into this CL system enhanced the CL *** was due to part of the energy transfer from singlet oxygen and excited triplet dimers of two CO2 molecules to rhodamine B or *** CL could be induced by excited rhodamine B or uranine.

关键词： chemiluminescence potassium permanganate emitting species energy transfer

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