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An unprotected vulnerable relict subtropical conifer-Keteleeria evelyniana: Its forests, populations, growth and endangerment by invasive alien plant species in China

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Plant Diversity 2024年第5期46卷 648-660页

作者： Cindy Q.Tang Min-Rui Du Huan-Chong Wang You-cai Shi Jia-Le Zeng Shu-Li Xiao Peng-Bin Han Jian-Ran Wen Shi-Qian Yao Ming-Chun Peng Chong-Yun Wang Yong-ping Li Jordi López-Pujol Institute of Ecology and Geobotany College of Ecology and Environmental ScienceYunnan UniversityBuilding#3Guozhong DalouDongwaihuan South RoadUniversity TownChenggong New DistrictKunming 650504YunnanChina College of Life Sciences Yunnan UniversityShengming Kexueyuan Building#2Chenggong CampusDongwaihuan South RoadUniversity TownChenggong New DistrictKunming 650504YunnanChina College of Natural Resources Yunnan UniversityChenggong CampusDongwaihuan South RoadUniversity TownChenggong New DistrictKunming 650504YunnanChina Botanic Institute of Barcelona(IBB CSIC-CMCNC)Passeig del Migdia s/nBarcelona 08038CataloniaSpain Escuela de Ciencias Ambientales Universidad Espíritu Santo(UEES)Samborondon 091650Ecuador

Relict subtropical coniferous forests in China face severe fragmentation,resulting in declining populations,and some are under significant threat from invasive alien *** the crucial importance of understanding forest dynamics,knowledge gaps persist,particularly regarding the impact of invasive plants on vulnerable natives like Keteleeria *** this study,we investigated the impact of invasive plants on the regeneration of forests dominated by ***,a subtropical relict species in southwestern *** this purpose,we characterized forest dynamics of 160 forest plots featuring *** as the primary dominant species and determined whether the presence of invasive plants was correlated with regeneration of *** identified four distinct forest types in which *** was *** found that radial growth of *** trees is faster in younger ageclasses today than it was for older trees at the same *** population structure of *** in each forest type exhibited a multimodal age-class ***,three forest types lacked established saplings younger than 10 years old,a situation attributed to the dense coverage of the invasive alien Ageratina *** invasive species resulted in a reduction of understory species ***,our analysis uncovered a significant negative correlation in phylogenetic relatedness(net relatedness index)between native and invasive alien plant species in eastern *** suggests closely related invasive species face heightened competition,hindering successful *** together,our findings indicate that successful establishment and habitat restoration of *** seedling/saplings require effective measures to control invasive plants.

关键词： Keteleeria evelyniana Age structure Regeneration Species diversity Invasive alien species Phylogenetic relatedness

Coupling and characterization of a Si/SiGe triple quantum dot array with a microwave resonator

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Chinese Physics B 2024年第9期33卷 139-143页

作者： Shun-Li Jiang Tian-Yi Jiang Yong-Qiang Xu Rui Wu Tian-Yue Hao Shu-Kun Ye Ran-Ran cai Bao-Chuan Wang Hai-Ou Li Gang Cao Guo-ping Guo CAS Key Laboratory of Quantum Information University of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China Origin Quantum Computing Company Limited Hefei 230088China

Scaling up spin qubits in silicon-based quantum dots is one of the pivotal challenges in achieving large-scale semiconductor quantum *** satisfy the connectivity requirements and reduce the lithographic complexity,utilizing the qubit array structure and the circuit quantum electrodynamics(cQED)architecture together is expected to be a feasible scaling scheme.A triple-quantum dot(TQD)coupled with a superconducting resonator is regarded as a basic cell to demonstrate this extension *** this article,we investigate a system consisting of a silicon TQD and a high-impedance TiN coplanar waveguide(CPW)*** TQD can couple to the resonator via the right double-quantum dot(RDQD),which reaches the strong coupling regime with a charge–photon coupling strength of g0/(2p)=175 ***,we illustrate the high tunability of the TQD through the characterization of stability diagrams,quadruple points(QPs),and the quantum cellular automata(QCA)*** results contribute to fostering the exploration of silicon-based qubit integration.

关键词： triple-quantum dot strong coupling circuit quantum electrodynamics (cQED) scalable siliconbased cQED architectures

基于贝叶斯网络的生态系统服务权衡协同关系强度及其空间格局优化:以汾河流域为例

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环境科学 2024年第5期45卷 2780-2792页

作者：蔡进危小建江平梁玉琦东华理工大学自然资源部环鄱阳湖区域矿山环境监测与治理重点实验室南昌330013 东华理工大学测绘与空间信息工程学院南昌330013 江西省测绘地理信息工程技术研究中心南昌330025 武汉大学资源与环境科学学院武汉430079

了解生态系统服务(ESs)间权衡协同关系强度对于汾河流域地区的生态环境管理和恢复至关重要,然而,迄今为止,对该地区ESs间关系强度变化的驱动变量和空间格局优化仍然缺乏足够的研究.在定量评估汾河流域2000年和2020年6种生态系统服务的... 详细信息

了解生态系统服务(ESs)间权衡协同关系强度对于汾河流域地区的生态环境管理和恢复至关重要,然而,迄今为止,对该地区ESs间关系强度变化的驱动变量和空间格局优化仍然缺乏足够的研究.在定量评估汾河流域2000年和2020年6种生态系统服务的基础上,引入了生态系统服务权衡协同指数(TSI)定量衡量两两ES间权衡协同关系的强度,同时构建了贝叶斯生态系统服务权衡协同关系强度网络,识别了权衡协同强度的驱动变量,通过敏感度分析确定了关键变量对权衡协同关系强度的影响程度,并在空间格局上刻画了ESs权衡协同关系强度的优化区.结果表明:①2000年和2020年汾河流域6种ESs时空差异较为显著,在时间尺度上,产水量、净初级生产力、粮食供给、土壤保持和碳储量均呈现波动上升的趋势,在空间尺度上,6种生态系统服务在20年里空间分布变化较小.②碳储量与生境质量、土壤保持以及净初级生产力的TSI在空间上呈现出四周高中部低的格局;与产水量有关的5对服务中TSI最大的地区均分布在流域西部和南部;粮食供给与其他服务之间的TSI自北向南呈现“高-中-高”的分布特征.③敏感性分析发现,产水量与土壤保持和生境质量的强度均受到降水、根系限制性深度和降雨侵蚀等的显著影响,且根据关键变量不同状态的条件概率,发现汾河流域中部的文水县、清徐县和祁县等是权衡协同强度的高值区,可作为生态修复重点区域.研究结果对于认识多种生态系统服务间权衡与协同强度的复杂关系及其驱动变量,对后续提出生态环境可持续治理和政策制定具有重要的理论和实践意义.

关键词：生态系统服务(ESs) 权衡协同指数(TSI) 贝叶斯网络区域优化汾河流域

Nomogram for predicting short-term response to anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration:An observational study

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World Journal of Radiology 2024年第9期16卷 418-428页

作者： Zhen-Huan Huang Xue-Zhao Tu Qi Lin Mei Tu Guo-cai Lin Kai-ping Zhang Department of Radiology Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 364000Fujian ProvinceChina Department of Orthopedics Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 364000Fujian ProvinceChina Department of Endocrinology Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 364000Fujian ProvinceChina Department of Ophthalmology Longyan First Affiliated Hospital of Fujian Medical UniversityLongyan 364000Fujian ProvinceChina

BACKGROUND Anti-vascular endothelial growth factor(anti-VEGF)therapy is critical for managing neovascular age-related macular degeneration(nAMD),but understanding factors influencing treatment efficacy is essential for optimizing patient *** To identify the risk factors affecting anti-VEGF treatment efficacy in nAMD and develop a predictive model for short-term *** In this study,65 eyes of exudative AMD patients after anti-VEGF treatment for≥1 mo were observed using optical coherence tomography *** were classified into non-responders(n=22)and responders(n=43).Logistic regression was used to determine independent risk factors for treatment response.A predictive model was created using the Akaike Information Criterion,and its performance was assessed with the area under the receiver operating characteristic curve,calibration curves,and decision curve analysis(DCA)with 500 bootstrap *** Multivariable logistic regression analysis identified the number of junction voxels[odds ratio=0.997,95%confidence interval(CI):0.993-0.999,P=0.010]as an independent predictor of positive anti-VEGF treatment *** predictive model incorporating the fractal dimension,number of junction voxels,and longest shortest path,achieved an area under the curve of 0.753(95%CI:0.622-0.873).Calibration curves confirmed a high agreement between predicted and actual outcomes,and DCA validated the model's clinical *** The predictive model effectively forecasts 1-mo therapeutic outcomes for nAMD patients undergoing anti-VEGF therapy,enhancing personalized treatment planning.

关键词： Vascular endothelial growth factor Macular degeneration Neovascularization Age-related macular degeneration Choroidal neovascularization Optical coherence tomography angiography Nomogram

Engineering of cofactor preference and catalytic activity of methanol dehydrogenase by growth-coupled directed evolution

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Green Carbon 2024年第2期2卷 242-251页

作者： Jinxing Yang Liwen Fan Guimin Cheng Tao cai Jibin Sun ping Zheng Shuang Li Yu Wang School of Biology and Biological Engineering South China University of TechnologyGuangzhou 510006China Haihe Laboratory of Synthetic Biology Tianjin 300308China Key Laboratory of Engineering Biology for Low-Carbon Manufacturing Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China National Technology Innovation Center of Synthetic Biology Tianjin 300308China College of Biotechnology Tianjin University of Science and TechnologyTianjin 300222China

Methanol,produced from carbon dioxide,natural gas,and biomass,has drawn increasing attention as a promising green carbon feedstock for biomanufacturing due to its sustainable and energy-rich *** adenine dinucleotide(NAD^(+))-dependent methanol dehydrogenase(MDH)catalyzes the oxidation of methanol to formaldehyde via NADH generation,providing a highly active C1 intermediate and reducing power for subsequent ***,the unsatisfactory catalytic efficiency and cofactor bias of MDH significantly impede methanol valorization,especially in nicotinamide adenine dinucleotide phosphate(NADP^(+))-dependent ***,we employed synthetic NADH and NADPH auxotrophic Escherichia coli strains as growth-coupled selection platforms for the directed evolution of MDH from Bacillus stearothermophilus DSM *** or NADPH generated by MDH-catalyzed methanol oxidation enabled the growth of synthetic cofactor auxotrophs,establishing a positive correlation between the cell growth rate and MDH *** this principle,MDH mutants exhibiting a 20-fold improvement in catalytic efficiency(k_(cat)/K_(m))and a 90-fold cofactor specificity switch from NAD^(+)to NADP+without a decrease in specific enzyme activity,were efficiently screened from random and semi-rationally designed *** envision that these mutants will advance methanol valorization and that the synthetic cofactor auxotrophs will serve as versatile selection platforms for the evolution of NAD(P)^(+)-dependent enzymes.

关键词： Growth-coupled screening Methanol dehydrogenase Cofactor engineering Directed evolution C1 bioconversion

Application and optimization design of non-obstructive particle damping-phononic crystal vibration isolator in viaduct structure-borne noise reduction

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Journal of Central South University 2024年第7期31卷 2513-2531页

作者： SHI Duo-jia ZHAO cai-you ZHANG Xin-hao ZHENG Jun-yuan WEI Na-chao WANG ping Key Laboratory of High-speed Railway Engineering Ministry of EducationSouthwest Jiaotong UniversityChengdu 610031China School of Civil Engineering Southwest Jiaotong UniversityChengdu 610031China

The problems associated with vibrations of viaducts and low-frequency structural noise radiation caused by train excitation continue to increase in importance.A new floating-slab track vibration isolator-non-obstructive particle damping-phononic crystal vibration isolator is proposed herein,which uses the particle damping vibration absorption technology and bandgap vibration control *** vibration reduction performance of the NOPD-PCVI was analyzed from the perspective of vibration *** paper explores the structure-borne noise reduction performance of the NOPD-PCVIs installed on different bridge structures under varying service conditions encountered in practical engineering *** load transferred to the bridge is obtained from a coupled train-FST-bridge analytical model considering the different structural parameters of *** vibration responses are obtained using the finite element method,while the structural noise radiation is simulated using the frequency-domain boundary element *** the particle swarm optimization algorithm,the parameters of the NOPD-PCVI are optimized so that its frequency bandgap matches the dominant bridge structural noise frequency *** noise reduction performance of the NOPD-PCVIs is compared to the steel-spring isolation under different service conditions.

关键词： non-obstructive particle damping phononic crystal vibration isolator band gap optimization floating-slab track bridge structure-borne noise control particle swarm optimization

Integrated application of synthetic community reduces consumption of herbicide in field Phalaris minor control

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Soil Ecology Letters 2024年第2期6卷 125-136页

作者： Amina Hadayat Zahir Ahmad Zahir Peng cai Chun-Hui Gao National Key Laboratory of Agricultural Microbiology College of Resources and EnvironmentHuazhong Agricultural UniversityWuhan430070China Soil Microbiology and Biochemistry Laboratory Institute of Soil and Environmental SciencesUniversity of AgricultureFaisalabadPakistan

Herbicide-based weeds control impacts wheat crops as *** of Pseudomonas strains reduce the need for high-dose herbicides.100%Axial provides less weed control compared to 75%Axial with C4 *** 75%with C4 SynCom promotes... 详细信息

关键词： weed control synthetic microbial communities Phalaris minor wheat growth promotion synergistic effect

Re-evaluating the necessity of routine laboratory monitoring during isotretinoin therapy for acne

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World Journal of Clinical Cases 2024年第28期12卷 6237-6240页

作者： Yun-Xia Zhu Liang Wu Sheng-cai Zhu Xiu-ping Wang Deng Zhang Yan-ping Tan Xiao-Liang Ouyang Chun-Ming Li Department of Dermatology The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina Department of Dermatology Jiangxi Provincial Maternal and Child Health HospitalNanchang 330000Jiangxi ProvinceChina Department of Plastic Surgery The Second Affiliated HospitalJiangxi Medical CollegeNanchang UniversityNanchang 330006Jiangxi ProvinceChina

In this letter,we discuss the topic of necessity of routine laboratory monitoring during isotretinoin treatment for *** to Park and colleagues,it is advisable to monitor the levels of triglycerides,alanine aminotransferase,and aspartate aminotransferase every 5 to 6 ***,the levels of total cholesterol and low-density lipoprotein should be checked within the first two months of *** is a commonly prescribed agent mainly used to treat *** its high effectiveness,it necessitates regular monitoring of laboratory parameters due to its side effect ***,there remains a lack of consensus on the appropriate frequency for monitoring these parameters during treatment with *** letter will provide insight into this complex and controversial *** on existing literature,we concluded that the incidence of changes in lipid and liver aminotransferase levels during isotretinoin treatment for acne was low and likely clinically *** generally healthy people,we recommend testing lipid and liver profiles once at baseline and a second time at the peak ***,frequent testing might still be beneficial in certain populations of patients.

关键词： Acne Isotretinoin Laboratory monitoring Liver function Blood lipids

Huoxue Tongjiang decoction-resisted reflux esophagitis by activation stem cell factor/c-kit/interstitial cell of cajal pathway and regulating the T-helper 17/regulatory T-cells balance in rats

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Traditional Medicine Research 2024年第12期9卷 1-12页

作者： Yan Liu Yan-ping Tang Pei-cai Li Lei Liu Xi Liu Si-Yu Liu Lei Yang Division of Gastroenterology Hospital of Integrated Chinese and Western MedicineTianjin University of Traditional Chinese MedicineTianjin 300000China Tianjin Key Laboratory of Acute Abdomen Disease Associated Organ Injury and ITCWM Repair Hospital of Integrated Chinese and Western MedicineTianjin 300000China Institute of Integrative Medicine for Acute Abdominal Diseases Hospital of Integrated Chinese and Western MedicineTianjin 300000China

Background:Huoxue Tongjiang decoction(HXTJD)is an effective prescription for treating reflux esophagitis(RE).We investigated the effects of HXTJD on esophageal motility and mucosal inflammation in a rat RE ***:Chemical composition of HXTJD was analyzed by ultrahigh-performance liquid chromatography Q-Orbitrap mass spectrometry(MS).The change rates of mean contraction tension forces,mean amplitudes,and mean frequencies for the lower esophageal sphincter(LES)were recorded using the isolated tissue bath system,mechanical tension transducer,and PowerLab physiological *** weighing the stomach,the phenol red labeling method was used to measure the gastric emptying *** LES ultrastructure was observed through transmission electron *** and western blotting were used to detect the number of interstitial cells of Cajal(ICC)and the expression levels of c-kit protein,connexin43(Cx43),and stem cell factor(SCF).Flow cytometric analysis and enzyme-linked immunosorbent assay were conducted to detect the percentages of T helper 17(Th17)cells and regulatory T(Treg)cells and the serum concentrations of interleukin 6(IL-6),interleukin 17(IL-17),and interleukin 10(IL-10)in the ***:We identified 28 chemical constituents in *** esophageal motility,we revealed that HXTJD increased the mean contraction tension forces,mean amplitudes,and mean frequency change rate of LES and the gastric emptying rate;decreased stomach weight;and improved the LES ***,HXTJD increased the number of ICC-positive cells,and c-kit,Cx43,and SCF expression *** esophageal inflammation,HXTJD significantly decreased the percentage of Th17 cells,and IL-6 and IL-17 concentrations,and increased the percentage of Treg cells and IL-10 ***:HXTJD was found to be efficacious in the rat RE *** may promote esophageal motility and alleviate the inflammatory response by activating the SCF/c-kit/ICC

关键词： Huoxue Tongjiang decoction reflux esophagitis SCF/c-kit/ICC pathway Th17/Treg cell esophageal motility mucosal inflammation